Published in Gene Expr Patterns on August 01, 2003
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol (2007) 1.54
ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease. Circulation (2014) 1.18
Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice. Dev Biol (2008) 1.11
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart. Nat Commun (2014) 0.93
PGC-1α regulates normal and pathological angiogenesis in the retina. Am J Pathol (2012) 0.89
Chronic whole-body hypoxia induces intussusceptive angiogenesis and microvascular remodeling in the mouse retina. Microvasc Res (2010) 0.86
Apelin and pulmonary hypertension. Pulm Circ (2011) 0.86
Attenuation of ephrinB2 reverse signaling decreases vascularized area and preretinal vascular tuft formation in the murine model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci (2012) 0.81
MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation. Nat Commun (2016) 0.81
Altered vascular expression of EphrinB2 and EphB4 in a model of oxygen-induced retinopathy. Dev Dyn (2010) 0.80
Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse. Cardiovasc Res (2010) 0.80
Apelin is required for non-neovascular remodeling in the retina. Am J Pathol (2011) 0.79
Endothelium as a gatekeeper of fatty acid transport. Trends Endocrinol Metab (2013) 0.79
Apelin in epiretinal membranes of patients with proliferative diabetic retinopathy. Mol Vis (2014) 0.78
UXT potentiates angiogenesis by attenuating Notch signaling. Development (2015) 0.77
Effects of apelin on the cardiovascular system. Heart Fail Rev (2015) 0.77
Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery. J Med Chem (2015) 0.76
Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology (2005) 1.88
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors. Dev Cell (2007) 1.68
Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. FASEB J (2004) 1.29
The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase. J Biol Chem (2006) 1.15
The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments. J Biol Chem (2006) 1.12
Apelin (65-77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein. Biochem Biophys Res Commun (2002) 1.08
Expression of the murine msr/apj receptor and its ligand apelin is upregulated during formation of the retinal vessels. Mech Dev (2002) 1.06
Therapeutic potential of interfering with apelin signalling. Drug Discov Today (2006) 1.03
[Apelin signalisation and vascular physiopathology]. J Soc Biol (2009) 0.85