Published in Dev Biol on January 22, 2008
Expression Profiling of Genes Related to Endothelial Cells Biology in Patients with Type 2 Diabetes and Patients with Prediabetes. Biomed Res Int (2016) 1.39
CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression. Blood (2008) 1.33
Role of PECAM-1 in arteriogenesis and specification of preexisting collaterals. Circ Res (2010) 1.20
Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol (2009) 1.18
Cell biology of embryonic migration. Birth Defects Res C Embryo Today (2008) 1.14
Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia. Endocrinology (2008) 1.08
PECAM-1: regulator of endothelial junctional integrity. Cell Tissue Res (2014) 1.05
Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1. Am J Pathol (2011) 1.00
Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases. Circ Res (2012) 1.00
PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions. Am J Physiol Cell Physiol (2010) 0.95
Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways. J Cell Sci (2013) 0.93
Opposing effects of bim and bcl-2 on lung endothelial cell migration. Am J Physiol Lung Cell Mol Physiol (2010) 0.90
PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis. Clin Sci (Lond) (2015) 0.85
Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1α-VEGF pathway inhibition. Diabetes (2014) 0.83
A murine model for retinopathy of prematurity identifies endothelial cell proliferation as a potential mechanism for plus disease. Invest Ophthalmol Vis Sci (2013) 0.82
Proteomic analysis of the hyaloid vascular system regression during ocular development. J Proteome Res (2008) 0.81
SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility. Am J Physiol Cell Physiol (2010) 0.81
Altered vascular expression of EphrinB2 and EphB4 in a model of oxygen-induced retinopathy. Dev Dyn (2010) 0.80
The hematopoietic chemokine CXCL12 promotes integration of human endothelial colony forming cell-derived cells into immature vessel networks. Stem Cells Dev (2014) 0.80
PTH receptor signaling in osteoblasts regulates endochondral vascularization in maintenance of postnatal growth plate. J Bone Miner Res (2015) 0.78
EC-18, a synthetic monoacetyldiacylglyceride, inhibits hematogenous metastasis of KIGB-5 biliary cancer cell in hamster model. J Korean Med Sci (2009) 0.78
A comparing study of quantitative staining techniques for retinal neovascularization in a mouse model of oxygen-induced retinopathy. Int J Ophthalmol (2012) 0.78
Caspase-14: a novel caspase in the retina with a potential role in diabetic retinopathy. Mol Vis (2012) 0.77
Inhibition of lung tumor growth in nude mice by siRNA(CD31) targeting PECAM-1. Oncol Lett (2014) 0.76
Influence of PECAM-1 ligand interactions on PECAM-1-dependent cell motility and filopodia extension. Physiol Rep (2016) 0.75
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell (1998) 10.61
Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci (1994) 10.46
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature (2005) 6.86
Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation (2006) 5.91
Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci U S A (1995) 5.66
Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell (1999) 4.17
Development of the retinal vasculature. Angiogenesis (2007) 2.93
Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proc Natl Acad Sci U S A (2005) 2.81
EndoCAM: a novel endothelial cell-cell adhesion molecule. J Cell Biol (1990) 2.71
Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions. J Immunol (1999) 2.55
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J Clin Invest (2002) 2.50
Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion. Invest Ophthalmol Vis Sci (2002) 2.46
Flow regulates arterial-venous differentiation in the chick embryo yolk sac. Development (2003) 2.43
Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis. Invest Ophthalmol Vis Sci (2002) 2.23
Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am J Pathol (1997) 2.17
Regression of the hyaloid vessels and pupillary membrane of the mouse. Anat Embryol (Berl) (1999) 2.06
Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J Cell Sci (2005) 1.95
Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique. Blood (2005) 1.92
EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells. FASEB J (2002) 1.58
Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice. Invest Ophthalmol Vis Sci (2001) 1.57
Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration. Dev Dyn (2003) 1.53
Signaling through CD31 protects endothelial cells from apoptosis. Transplantation (2001) 1.50
EphB4 controls blood vascular morphogenesis during postnatal angiogenesis. EMBO J (2006) 1.48
PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler Thromb Vasc Biol (2005) 1.47
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood (2005) 1.47
PECAM-1 interacts with nitric oxide synthase in human endothelial cells: implication for flow-induced nitric oxide synthase activation. Arterioscler Thromb Vasc Biol (2004) 1.39
Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway. J Biol Chem (2002) 1.37
Loss of PECAM-1 function impairs alveolarization. J Biol Chem (2005) 1.35
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. Blood (2003) 1.33
Lack of platelet endothelial cell adhesion molecule-1 attenuates foreign body inflammation because of decreased angiogenesis. Am J Pathol (2003) 1.16
Homophilic PECAM-1(CD31) interactions prevent endothelial cell apoptosis but do not support cell spreading or migration. J Cell Sci (1999) 1.14
PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol (2007) 1.14
Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells. Blood (2002) 1.12
Normal vascular development in mice deficient in endothelial NO synthase: possible role of neuronal NO synthase. Mol Vis (2003) 1.09
Soluble forms of EphrinB2 and EphB4 reduce retinal neovascularization in a model of proliferative retinopathy. Invest Ophthalmol Vis Sci (2005) 1.07
Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. Mol Biol Cell (1997) 1.06
Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts. Biochem J (2002) 1.05
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. Am J Physiol Regul Integr Comp Physiol (2005) 1.05
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization. Invest Ophthalmol Vis Sci (2005) 1.04
Nitric oxide is proangiogenic in the retina and choroid. J Cell Physiol (2002) 1.03
EphB4 expression along adult rat microvascular networks: EphB4 is more than a venous specific marker. Microcirculation (2007) 1.01
The msr/apj gene encoding the apelin receptor is an early and specific marker of the venous phenotype in the retinal vasculature. Gene Expr Patterns (2003) 1.00
Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2. J Biol Chem (2005) 1.00
Oxygen modifies artery differentiation and network morphogenesis in the retinal vasculature. Dev Dyn (2005) 0.98
Role of ephrin B2 in human retinal endothelial cell proliferation and migration. Cell Signal (2003) 0.97
Effect of increased oxygen on the development of the retinal vessels; an experimental study. Br J Ophthalmol (1954) 0.96
PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: implications in inflammation and angiogenesis. J Cell Biochem (2006) 0.95
Endothelial ephrinB2 is controlled by microenvironmental determinants and associates context-dependently with CD31. Arterioscler Thromb Vasc Biol (2005) 0.90
Defective lung vascular development in endothelial nitric oxide synthase-deficient mice. Trends Cardiovasc Med (2006) 0.87
Down-regulation of endothelial ephrinB2 expression by laminar shear stress. Endothelium (2005) 0.86
KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetic patients. Clin Exp Pharmacol Physiol (2012) 2.23
Isolation and characterization of murine retinal endothelial cells. Mol Vis (2003) 1.80
Hypoxic induction of endoglin via mitogen-activated protein kinases in mouse brain microvascular endothelial cells. Stroke (2003) 1.70
Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration. Dev Dyn (2003) 1.53
Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach. J Proteome Res (2010) 1.47
Leflunomide: friend or foe for systemic lupus erythematosus? Rheumatol Int (2012) 1.45
Overexpression of glucose-regulated protein 78 in colon cancer. Clin Chim Acta (2005) 1.42
High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs. Am J Physiol Cell Physiol (2008) 1.41
Correlation of hypocalcemia with serum parathyroid hormone and calcitonin levels in pediatric intensive care unit. Indian J Pediatr (2014) 1.38
Analysis of SOX9 expression in colorectal cancer. Am J Clin Pathol (2008) 1.35
CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression. Blood (2008) 1.33
IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. Cancer Biol Ther (2007) 1.30
Attenuation of proliferation and migration of retinal pericytes in the absence of thrombospondin-1. Am J Physiol Cell Physiol (2009) 1.22
Fast spin state initialization in a singly charged InAs-GaAs quantum dot by optical cooling. Phys Rev Lett (2007) 1.22
Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice. Diabetes (2012) 1.21
Calcitriol is a potent inhibitor of retinal neovascularization. Invest Ophthalmol Vis Sci (2007) 1.15
PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol (2007) 1.14
Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis (2011) 1.12
IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1. J Zhejiang Univ Sci B (2006) 1.12
Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes (2011) 1.11
Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms. Am J Physiol Heart Circ Physiol (2002) 1.10
Bcl-2 expression modulates cell adhesion and migration promoting branching of ureteric bud cells. J Cell Physiol (2007) 1.09
Regulation of angiogenesis by histone chaperone HIRA-mediated incorporation of lysine 56-acetylated histone H3.3 at chromatin domains of endothelial genes. J Biol Chem (2010) 1.09
Increased synthesis of leukotrienes in the mouse model of diabetic retinopathy. Invest Ophthalmol Vis Sci (2009) 1.08
Effect of eIF3a on response of lung cancer patients to platinum-based chemotherapy by regulating DNA repair. Clin Cancer Res (2011) 1.08
Attenuation of retinal vascular development and neovascularization during oxygen-induced ischemic retinopathy in Bcl-2-/- mice. Dev Biol (2005) 1.08
Heparin II domain of fibronectin uses alpha4beta1 integrin to control focal adhesion and stress fiber formation, independent of syndecan-4. J Biol Chem (2004) 1.08
Differential expression of mimecan and thioredoxin domain-containing protein 5 in colorectal adenoma and cancer: a proteomic study. Exp Biol Med (Maywood) (2007) 1.07
Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population. Pharmacogenet Genomics (2009) 1.06
Less cytotoxicity to combination therapy of 5-fluorouracil and cisplatin than 5-fluorouracil alone in human colon cancer cell lines. World J Gastroenterol (2002) 1.05
Regulation of cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells by convergence of distinct beta1 and beta3 integrin pathways. Invest Ophthalmol Vis Sci (2009) 1.05
Isolation and characterization of murine retinal astrocytes. Mol Vis (2005) 1.04
PEDF-deficient mice exhibit an enhanced rate of retinal vascular expansion and are more sensitive to hyperoxia-mediated vessel obliteration. Exp Eye Res (2008) 1.04
Attenuation of retinal vascular development and neovascularization in transgenic mice over-expressing thrombospondin-1 in the lens. Dev Dyn (2006) 1.03
A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis. Arterioscler Thromb Vasc Biol (2010) 1.01
Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1. Am J Pathol (2011) 1.00
A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer. Biochem Biophys Res Commun (2004) 0.99
Polyoma virus middle-T-transformed PECAM-1 deficient mouse brain endothelial cells proliferate rapidly in culture and form hemangiomas in mice. J Cell Physiol (2005) 0.99
Attenuation of retinal endothelial cell migration and capillary morphogenesis in the absence of bcl-2. Am J Physiol Cell Physiol (2008) 0.99
Meta-analysis on pharmacogenetics of platinum-based chemotherapy in non small cell lung cancer (NSCLC) patients. PLoS One (2012) 0.99
Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro. Cancer Biol Ther (2008) 0.97
Formation of the molten globule-like state during prolonged glycation of human serum albumin. Biochim Biophys Acta (2007) 0.97
Isolation and characterization of corneal endothelial cells from wild type and thrombospondin-1 deficient mice. Mol Vis (2007) 0.97
High glucose and diabetes modulate cellular proteasome function: Implications in the pathogenesis of diabetes complications. Biochem Biophys Res Commun (2013) 0.95
Inhibitory effects of arresten on bFGF-induced proliferation, migration, and matrix metalloproteinase-2 activation in mouse retinal endothelial cells. Curr Eye Res (2010) 0.95
PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: implications in inflammation and angiogenesis. J Cell Biochem (2006) 0.95
PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions. Am J Physiol Cell Physiol (2010) 0.95
Lack of thrombospondin 1 and exacerbation of choroidal neovascularization. Arch Ophthalmol (2012) 0.94
Alterations in cell-adhesive and migratory properties of proximal tubule and collecting duct cells from bcl-2 -/- mice. Am J Physiol Renal Physiol (2004) 0.94
MyD88-dependent pathways in leukocytes affect the retina in diabetes. PLoS One (2013) 0.94
Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucose-induced oxidative stress and apoptosis. J Pharmacol Exp Ther (2012) 0.94
Identification of differentially expressed proteins in colorectal cancer by proteomics: down-regulation of secretagogin. Proteomics (2006) 0.94
Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways. J Cell Sci (2013) 0.93
Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells. Microvasc Res (2006) 0.93
Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases. J Cell Biochem (2003) 0.92
Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation. PLoS One (2012) 0.92
Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence. J Cancer Res Clin Oncol (2008) 0.92
Sustained activation of MAPK/ERKs signaling pathway in cystic kidneys from bcl-2 -/- mice. Am J Physiol Renal Physiol (2002) 0.91
Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration. Arch Ophthalmol (2010) 0.91
Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway. Exp Cell Res (2010) 0.91
Expression pattern of alternatively spliced PECAM-1 isoforms in hematopoietic cells and platelets. J Cell Biochem (2002) 0.91
FAK and p38-MAP kinase-dependent activation of apoptosis and caspase-3 in retinal endothelial cells by alpha1(IV)NC1. Invest Ophthalmol Vis Sci (2009) 0.91