Published in BMC Med Genomics on November 11, 2008
Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1). J Toxicol Environ Health A (2010) 1.02
Switching off malignant mesothelioma: exploiting the hypoxic microenvironment. Genes Cancer (2016) 0.75
Pathway deviation-based biomarker and multi-effect target identification in asbestos-related squamous cell carcinoma of the lung. Int J Mol Med (2017) 0.75
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
The Gene Ontology (GO) project in 2006. Nucleic Acids Res (2006) 13.79
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med (2000) 5.90
Ubiquitylation and cell signaling. EMBO J (2005) 4.65
Iterative Group Analysis (iGA): a simple tool to enhance sensitivity and facilitate interpretation of microarray experiments. BMC Bioinformatics (2004) 3.57
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Ubiquitin and ubiquitin-like proteins in cancer pathogenesis. Nat Rev Cancer (2006) 2.90
Calcium and cancer: targeting Ca2+ transport. Nat Rev Cancer (2007) 2.65
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Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clin Cancer Res (2005) 1.99
Ion channels in cell proliferation and apoptotic cell death. J Membr Biol (2005) 1.69
Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am J Respir Cell Mol Biol (2006) 1.51
Induction by asbestos fibers of anaphase abnormalities: mechanism for aneuploidy induction and possibly carcinogenesis. Carcinogenesis (1985) 1.46
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A gene from human chromosome region 3p21 with reduced expression in small cell lung cancer. Cancer Res (1992) 1.15
Mechanisms of the combined effect of asbestos and smoking in the etiology of lung cancer. Scand J Work Environ Health (1994) 1.14
Asbestos exposure and the risk of lung cancer in a general urban population. Scand J Work Environ Health (1994) 1.14
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines. BMC Genomics (2007) 1.12
Voltage-gated Na+ channels: multiplicity of expression, plasticity, functional implications and pathophysiological aspects. Eur Biophys J (2004) 1.09
Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme. J Biochem (2005) 1.08
Inherited sodium channelopathies: a continuum of channel dysfunction. Trends Cardiovasc Med (2004) 1.07
Asbestos-induced pulmonary toxicity: role of DNA damage and apoptosis. Exp Biol Med (Maywood) (2003) 1.02
The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis. Am J Respir Cell Mol Biol (2003) 0.99
Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res (2006) 0.97
Exposure to crocidolite and the incidence of different histological types of lung cancer. Occup Environ Med (1996) 0.96
Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer. Oncogene (2007) 0.95
Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin-proteasome pathway as a therapeutic target in poor prognosis tumors. Oncogene (2006) 0.91
Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer. Cancer Res (2004) 0.90
Lung cancer cell type and asbestos exposure. JAMA (1985) 0.88
Incidence of cancer among Finnish patients with asbestos-related pulmonary or pleural fibrosis. Cancer Causes Control (1999) 0.88
Human muscle voltage-gated ion channels and hereditary disease. Curr Opin Pharmacol (2001) 0.88
Asbestos exposure among Finnish lung cancer patients: occupational history and fiber concentration in lung tissue. Am J Ind Med (1993) 0.87
Levels of 8-hydroxy-2'-deoxyguanosine in DNA of white blood cells from workers highly exposed to asbestos in Germany. Mutat Res (2000) 0.87
Cell signaling pathways elicited by asbestos. Environ Health Perspect (1997) 0.84
Molecular interplay between ion channels and the regulation of apoptosis. Biol Res (2002) 0.82
Increased incidence of DNA double-strand breaks and anti-ds DNA antibodies in blood of workers occupationally exposed to asbestos. Hum Exp Toxicol (1994) 0.81
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature (2006) 3.60
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet (2008) 2.79
Review: Biological relevance of disseminated tumor cells in cancer patients. Int J Cancer (2008) 2.72
CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma -A miRNA microarray analysis. Genes Chromosomes Cancer (2009) 2.09
Uniparental disomy in cancer. Trends Mol Med (2009) 1.99
Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity. PLoS Med (2008) 1.94
Specificity, selection and significance of gene amplifications in cancer. Semin Cancer Biol (2006) 1.86
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell (2008) 1.82
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS. Genes Chromosomes Cancer (2013) 1.77
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis (2006) 1.70
Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer. Cancer Genet Cytogenet (2004) 1.54
Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families. Cancer Res (2002) 1.54
Manifestation, mechanisms and mysteries of gene amplifications. Cancer Lett (2005) 1.53
Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia. Blood (2003) 1.52
Absence of CCR4 exacerbates skin inflammation in an oxazolone-induced contact hypersensitivity model. J Invest Dermatol (2010) 1.51
Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro. Physiol Genomics (2007) 1.51
Peroxiredoxins and tropomyosins as plasma biomarkers for lung cancer and asbestos exposure. Lung Cancer (2012) 1.49
Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res (2002) 1.46
Driver gene mutations of non-small-cell lung cancer are rare in primary carcinoids of the lung: NGS study by ion Torrent. Lung (2015) 1.45
The catalytic cycle of cytochrome c oxidase is not the sum of its two halves. Proc Natl Acad Sci U S A (2003) 1.41
Undifferentiated intimal sarcoma of large systemic blood vessels: report of 14 cases with immunohistochemical profile and review of the literature. Am J Surg Pathol (2005) 1.40
Infantile onset spinocerebellar ataxia is caused by recessive mutations in mitochondrial proteins Twinkle and Twinky. Hum Mol Genet (2005) 1.38
CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Genes Chromosomes Cancer (2005) 1.38
Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array. Oncogene (2002) 1.38
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis. Haematologica (2002) 1.37
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J Pathol (2012) 1.34
Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP. Cancer Res (2002) 1.33
Acute lymphoblastic leukemia in adolescents and young adults in Finland. Haematologica (2008) 1.32
Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. Clin Cancer Res (2003) 1.31
CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis. Carcinogenesis (2003) 1.28
Distinct differentiation characteristics of individual human embryonic stem cell lines. BMC Dev Biol (2006) 1.24
MicroRNA profiling differentiates colorectal cancer according to KRAS status. Genes Chromosomes Cancer (2011) 1.24
Proteomic characterization of engineered nanomaterial-protein interactions in relation to surface reactivity. ACS Nano (2011) 1.24
Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis (2005) 1.23
Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. Oncogene (2005) 1.22
Gating of proton and water transfer in the respiratory enzyme cytochrome c oxidase. Proc Natl Acad Sci U S A (2005) 1.20
Unregulated smooth-muscle myosin in human intestinal neoplasia. Proc Natl Acad Sci U S A (2008) 1.20
Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas. Cancer Res (2005) 1.19
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion. Clin Cancer Res (2009) 1.19
Can bladder adenocarcinomas be distinguished from schistosomiasis-associated bladder cancers by using array comparative genomic hybridization analysis? Cancer Genet Cytogenet (2007) 1.16
Targeted resequencing reveals ALK fusions in non-small cell lung carcinomas detected by FISH, immunohistochemistry, and real-time RT-PCR: a comparison of four methods. Biomed Res Int (2013) 1.15
Epigenetic signatures of familial cancer are characteristic of tumor type and family category. Cancer Res (2008) 1.15
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines. BMC Genomics (2007) 1.12
Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators. Oncogene (2004) 1.12
Cytogenetic and molecular genetic changes in malignant mesothelioma. Cancer Genet Cytogenet (2006) 1.12
Array CGH in molecular diagnosis of mental retardation - A study of 150 Finnish patients. Am J Med Genet A (2010) 1.12
Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors. Clin Cancer Res (2009) 1.12
ALK/EML4 fusion gene may be found in pure squamous carcinoma of the lung. J Thorac Oncol (2014) 1.11
Aberrant p16 promoter methylation in smokers and former smokers with nonsmall cell lung cancer. Int J Cancer (2003) 1.09
Candidate driver genes in microsatellite-unstable colorectal cancer. Int J Cancer (2011) 1.08
Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes. Int J Cancer (2008) 1.07
Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome. J Clin Oncol (2009) 1.07
Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia. Leuk Lymphoma (2003) 1.07
Genomic imbalances in Schistosoma-associated and non-Schistosoma-associated bladder carcinoma. An array comparative genomic hybridization analysis. Cancer Genet Cytogenet (2007) 1.06
Characterization of recombinant amino-terminal NC4 domain of human collagen IX: interaction with glycosaminoglycans and cartilage oligomeric matrix protein. J Biol Chem (2004) 1.05
Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma. Br J Haematol (2003) 1.05
Combined use of expression and CGH arrays pinpoints novel candidate genes in Ewing sarcoma family of tumors. BMC Cancer (2009) 1.04
Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes. Genes Chromosomes Cancer (2007) 1.04
Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review. Am J Epidemiol (2009) 1.04
CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. Biomarkers (2005) 1.02
Changes in apoptosis-related pathways in acute myelocytic leukemia. Cancer Genet Cytogenet (2003) 1.01
Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma. Cancer Genet Cytogenet (2002) 1.00
Indicative oligodendrocyte dysfunction in spinal cords of human fetuses suffering from a lethal motoneuron disease. J Neurobiol (2005) 1.00
Targeted resequencing of 9p in acute lymphoblastic leukemia yields concordant results with array CGH and reveals novel genomic alterations. Genomics (2013) 1.00
Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: a cDNA array study. Br J Haematol (2002) 1.00
Gene amplifications in osteosarcoma-CGH microarray analysis. Genes Chromosomes Cancer (2005) 0.99
CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: an array CGH study. Leuk Res (2008) 0.99
Predictive value of histopathologic parameters in early squamous cell carcinoma of oral tongue. Oral Oncol (2007) 0.99
Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer. Genes Chromosomes Cancer (2011) 0.99
Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases. Virchows Arch (2005) 0.99
COX-2 is widely expressed in metaplastic epithelium in pulmonary fibrous disorders. Am J Clin Pathol (2006) 0.98
Coamplified and overexpressed genes at ERBB2 locus in gastric cancer. Int J Cancer (2004) 0.98
Ultrastructural and chromosomal studies on manganese superoxide dismutase in malignant mesothelioma. Am J Respir Cell Mol Biol (2004) 0.98
Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumors. Genes Chromosomes Cancer (2007) 0.98
Does comparative genomic hybridization reveal distinct differences in DNA copy number sequence patterns between leiomyosarcoma and malignant fibrous histiocytoma? Cancer Genet Cytogenet (2008) 0.98
Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res (2006) 0.97
CanGEM: mining gene copy number changes in cancer. Nucleic Acids Res (2007) 0.97
Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas. Mol Cancer Res (2006) 0.97
Sequence analysis of the cbb3 oxidases and an atomic model for the Rhodobacter sphaeroides enzyme. Biochemistry (2006) 0.97
Classification of human cancers based on DNA copy number amplification modeling. BMC Med Genomics (2008) 0.97