Published in J Biol Chem on August 14, 2003
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Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One (2010) 0.89
Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins. J Mol Cell Cardiol (2009) 0.87
Nitric oxide synthase inhibition affects sarcoplasmic reticulum Ca2+ release in skeletal muscle fibres from mouse. J Physiol (2005) 0.87
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RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. Cell (2008) 3.27
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The pore structure of the closed RyR1 channel. Structure (2005) 2.42
Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB J (2005) 1.97
Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A (2006) 1.85
Identification of cysteines involved in S-nitrosylation, S-glutathionylation, and oxidation to disulfides in ryanodine receptor type 1. J Biol Chem (2006) 1.85
Structure of calmodulin bound to the hydrophobic IQ domain of the cardiac Ca(v)1.2 calcium channel. Structure (2005) 1.83
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron (2008) 1.80
Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A (2008) 1.68
A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation. J Biol Chem (2006) 1.65
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc Res (2007) 1.63
Crosstalk between calcium and redox signaling: from molecular mechanisms to health implications. Antioxid Redox Signal (2008) 1.43
Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulins. Proc Natl Acad Sci U S A (2009) 1.41
Regulation of voltage-gated Ca2+ channels by calmodulin. Sci STKE (2006) 1.31
The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury. J Mol Cell Cardiol (2010) 1.31
Effects of S-glutathionylation and S-nitrosylation on calmodulin binding to triads and FKBP12 binding to type 1 calcium release channels. Antioxid Redox Signal (2005) 1.29
Structure of Ca2+ release channel at 14 A resolution. J Mol Biol (2005) 1.27
Apocalmodulin and Ca2+ calmodulin-binding sites on the CaV1.2 channel. Biophys J (2003) 1.26
Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proc Natl Acad Sci U S A (2011) 1.25
Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency. FASEB J (2004) 1.24
Characterization and temporal development of cores in a mouse model of malignant hyperthermia. Proc Natl Acad Sci U S A (2009) 1.22
A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice. Proc Natl Acad Sci U S A (2009) 1.22
Myotube depolarization generates reactive oxygen species through NAD(P)H oxidase; ROS-elicited Ca2+ stimulates ERK, CREB, early genes. J Cell Physiol (2006) 1.22
A noncontiguous, intersubunit binding site for calmodulin on the skeletal muscle Ca2+ release channel. J Biol Chem (2002) 1.19
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. Nat Med (2012) 1.19
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation. J Mol Cell Cardiol (2007) 1.18
Regulation of ryanodine receptors by FK506 binding proteins. Trends Cardiovasc Med (2004) 1.18
Dihydropyridine and ryanodine receptor binding after eccentric contractions in mouse skeletal muscle. J Appl Physiol (1985) (2003) 1.14
Regulation of voltage-gated Ca2+ channels by calmodulin. Sci STKE (2005) 1.13
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection. Cardiovasc Res (2007) 1.11
A Ca2+-binding domain in RyR1 that interacts with the calmodulin binding site and modulates channel activity. Biophys J (2005) 1.11
Lobe-dependent regulation of ryanodine receptor type 1 by calmodulin. J Biol Chem (2002) 1.10
Modulation of cardiac ryanodine receptor activity by ROS and RNS. Front Biosci (Landmark Ed) (2011) 1.09
NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells. J Biol Chem (2008) 1.08
Retracted C terminus L-type Ca2+ channel calmodulin-binding domains are 'auto-agonist' ligands in rabbit ventricular myocytes. J Physiol (2003) 1.07
Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF. Antioxid Redox Signal (2011) 1.04
The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A (2002) 1.04
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle. J Mol Cell Cardiol (2005) 1.02
Calmodulin interactions with IQ peptides from voltage-dependent calcium channels. Am J Physiol Cell Physiol (2004) 1.00
FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure. Hypertension (2007) 0.99
Sites on calmodulin that interact with the C-terminal tail of Cav1.2 channel. J Biol Chem (2004) 0.99
Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity. J Biol Chem (2011) 0.97
The ryanodine receptors Ca2+ release channels: cellular redox sensors? IUBMB Life (2005) 0.97
Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation. Antioxid Redox Signal (2014) 0.97
Superoxide-induced potentiation in the hippocampus requires activation of ryanodine receptor type 3 and ERK. J Neurophysiol (2008) 0.96
Calmodulin modulation of proteins involved in excitation-contraction coupling. Front Biosci (2002) 0.95
Exercise induces early and late myocardial preconditioning in dogs. Cardiovasc Res (2002) 0.95
Redox regulation of calcium release in skeletal and cardiac muscle. Biol Res (2002) 0.94
Phosphorylation of ryanodine receptors. Biol Res (2004) 0.93
Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury. J Cardiovasc Pharmacol (2014) 0.93
Determinants in CaV1 channels that regulate the Ca2+ sensitivity of bound calmodulin. J Biol Chem (2009) 0.92
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons. Cell Calcium (2006) 0.92
Signal transduction and gene expression regulated by calcium release from internal stores in excitable cells. Biol Res (2004) 0.91
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion. Biochim Biophys Acta (2009) 0.91
Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia. J Physiol (2013) 0.91
Eccentric contractions do not induce rhabdomyolysis in malignant hyperthermia susceptible mice. J Appl Physiol (1985) (2008) 0.90
Redox regulation of RyR-mediated Ca2+ release in muscle and neurons. Biol Res (2004) 0.89
Effect of iron on the activation of the MAPK/ERK pathway in PC12 neuroblastoma cells. Biol Res (2006) 0.89
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide. Free Radic Biol Med (2009) 0.89
High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and generates hydrogen peroxide, which jointly stimulate NF-κB activity. Antioxid Redox Signal (2010) 0.88
Effects of ATP, Mg2+, and redox agents on the Ca2+ dependence of RyR channels from rat brain cortex. Am J Physiol Cell Physiol (2007) 0.88
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem Biophys Res Commun (2009) 0.88
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex. J Neurosci (2008) 0.88
Effect of tachycardia on myocardial sarcoplasmic reticulum and Ca2+ dynamics: a mechanism for preconditioning? J Mol Cell Cardiol (2003) 0.88
Suramin interacts with the calmodulin binding site on the ryanodine receptor, RYR1. J Biol Chem (2002) 0.87
Mitochondria fine-tune the slow Ca(2+) transients induced by electrical stimulation of skeletal myotubes. Cell Calcium (2010) 0.84
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy. Cardiovasc Res (2013) 0.84
Increased hippocampal expression of the divalent metal transporter 1 (DMT1) mRNA variants 1B and +IRE and DMT1 protein after NMDA-receptor stimulation or spatial memory training. Neurotox Res (2009) 0.83
Calcium microdomains and gene expression in neurons and skeletal muscle cells. Cell Calcium (2006) 0.83
FKBP12 deficiency reduces strength deficits after eccentric contraction-induced muscle injury. J Appl Physiol (1985) (2008) 0.83
Insulin elicits a ROS-activated and an IP₃-dependent Ca²⁺ release, which both impinge on GLUT4 translocation. J Cell Sci (2014) 0.82
Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus. J Physiol (2002) 0.82
Cell signaling. Getting to the heart of mechanotransduction. Science (2011) 0.81
Fast kinetics of calcium dissociation from calsequestrin. Biol Res (2006) 0.80
Biochemical properties of V91G calmodulin: A calmodulin point mutation that deregulates muscle contraction in Drosophila. Protein Sci (2004) 0.80
Kinetic studies of calcium-induced calcium release in cardiac sarcoplasmic reticulum vesicles. Biophys J (2003) 0.80
Hypoxia stimulates via separate pathways ERK phosphorylation and NF-kappaB activation in skeletal muscle cells in primary culture. J Appl Physiol (1985) (2009) 0.80
Effect of prior exercise on thermal sensitivity of malignant hyperthermia-susceptible muscle. Muscle Nerve (2010) 0.79
Preconditioning tachycardia decreases the activity of the mitochondrial permeability transition pore in the dog heart. Biochem Biophys Res Commun (2011) 0.76
Exercise preconditioning of myocardial infarct size in dogs is triggered by calcium. J Cardiovasc Pharmacol (2015) 0.75
Amyloid β-peptide oligomers, ryanodine receptor-mediated Ca(2+) release, and Wnt-5a/Ca(2+) signaling: opposing roles in neuronal mitochondrial dynamics? Front Cell Neurosci (2013) 0.75
Role of essential oils in control of Rhizoctonia damping-off in tomato with bioactive Monarda herbage. Phytopathology (2010) 0.75
Redox-sensitive stimulation of type-1 ryanodine receptors by the scorpion toxin maurocalcine. Cell Calcium (2013) 0.75
Calcium signaling: a universal mechanism of cellular communication. Biol Res (2004) 0.75