Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.
|
Nat Prod Rep
|
2013
|
5.38
|
2
|
Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone.
|
J Am Chem Soc
|
2003
|
1.67
|
3
|
Distribution and evolution of circular miniproteins in flowering plants.
|
Plant Cell
|
2008
|
1.37
|
4
|
Cyclotides: a novel type of cytotoxic agents.
|
Mol Cancer Ther
|
2002
|
1.32
|
5
|
Cytotoxic cyclotides from Viola tricolor.
|
J Nat Prod
|
2004
|
1.18
|
6
|
Selective cytotoxicity evaluation in anticancer drug screening of fractionated plant extracts.
|
J Biomol Screen
|
2002
|
1.18
|
7
|
A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae).
|
Plant Cell
|
2005
|
1.16
|
8
|
Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa.
|
Biopolymers
|
2010
|
1.13
|
9
|
Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids.
|
J Agric Food Chem
|
2012
|
1.10
|
10
|
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
|
Proc Natl Acad Sci U S A
|
2013
|
1.07
|
11
|
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold.
|
J Biol Chem
|
2009
|
1.05
|
12
|
Variations in cyclotide expression in viola species.
|
J Nat Prod
|
2004
|
1.00
|
13
|
The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.
|
Chembiochem
|
2007
|
0.99
|
14
|
Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa.
|
J Nat Prod
|
2010
|
0.98
|
15
|
Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes.
|
J Nat Prod
|
2007
|
0.98
|
16
|
The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria.
|
J Antimicrob Chemother
|
2010
|
0.97
|
17
|
Naturally occurring xanthones; latest investigations: isolation, structure elucidation and chemosystematic significance.
|
Curr Med Chem
|
2009
|
0.96
|
18
|
The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: discovery of an active cardiac glycoside from Urginea maritima.
|
J Ethnopharmacol
|
2012
|
0.89
|
19
|
Natural products in modern life science.
|
Phytochem Rev
|
2010
|
0.89
|
20
|
Ultra-stable peptide scaffolds for protein engineering-synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2.
|
Chembiochem
|
2008
|
0.89
|
21
|
Chemistry and biology of cyclotides: circular plant peptides outside the box.
|
J Nat Prod
|
2014
|
0.89
|
22
|
Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice.
|
Biopolymers
|
2010
|
0.88
|
23
|
Primary and 3-D modelled structures of two cyclotides from Viola odorata.
|
Phytochemistry
|
2003
|
0.88
|
24
|
Antifouling activity of brominated cyclopeptides from the marine sponge Geodia barretti.
|
J Nat Prod
|
2004
|
0.86
|
25
|
Cyclotide proteins and precursors from the genus Gloeospermum: filling a blank spot in the cyclotide map of Violaceae.
|
Phytochemistry
|
2009
|
0.86
|
26
|
Interlocking disulfides in circular proteins: toward efficient oxidative folding of cyclotides.
|
Antioxid Redox Signal
|
2010
|
0.86
|
27
|
Cyclotide-membrane interactions: defining factors of membrane binding, depletion and disruption.
|
Biochim Biophys Acta
|
2011
|
0.85
|
28
|
Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin.
|
Peptides
|
2006
|
0.84
|
29
|
Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands.
|
J Nat Prod
|
2006
|
0.84
|
30
|
The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity.
|
Phytochemistry
|
2008
|
0.84
|
31
|
Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands.
|
J Nat Prod
|
2011
|
0.83
|
32
|
A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products.
|
J Nat Prod
|
2002
|
0.81
|
33
|
Biomedicine in the environment: cyclotides constitute potent natural toxins in plants and soil bacteria.
|
Environ Toxicol Chem
|
2011
|
0.81
|
34
|
Cycloviolacin O2 (CyO2) suppresses productive infection and augments the antiviral efficacy of nelfinavir in HIV-1 infected monocytic cells.
|
Biopolymers
|
2013
|
0.81
|
35
|
Recruitment in the field of Balanus improvisus and Mytilus edulis in response to the antifouling cyclopeptides barettin and 8,9-dihydrobarettin from the marine sponge Geodia barretti.
|
Biofouling
|
2004
|
0.81
|
36
|
Chemical composition and repellency of essential oils from four medicinal plants against Ixodes ricinus nymphs (Acari: Ixodidae).
|
J Med Entomol
|
2012
|
0.81
|
37
|
Cytotoxic potency of small macrocyclic knot proteins: structure-activity and mechanistic studies of native and chemically modified cyclotides.
|
Org Biomol Chem
|
2011
|
0.80
|
38
|
Antifouling activity of a dibrominated cyclopeptide from the marine sponge Geodia barretti.
|
J Nat Prod
|
2008
|
0.78
|
39
|
A liquid chromatography-electrospray ionization-mass spectrometry method for quantification of cyclotides in plants avoiding sorption during sample preparation.
|
J Chromatogr A
|
2011
|
0.78
|
40
|
Two brominated cyclic dipeptides released by the coldwater marine sponge Geodia barretti act in synergy as chemical defense.
|
J Nat Prod
|
2011
|
0.78
|
41
|
Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation.
|
Int J Pept Res Ther
|
2012
|
0.78
|
42
|
Cyclization of pyrrhocoricin retains structural elements crucial for the antimicrobial activity of the native peptide.
|
Biopolymers
|
2004
|
0.78
|
43
|
The flavouring phytochemical 2-pentanone reduces prostaglandin production and COX-2 expression in colon cancer cells.
|
Biol Pharm Bull
|
2008
|
0.77
|
44
|
Antimicrobial activity of filamentous fungi isolated from highly antibiotic-contaminated river sediment.
|
Infect Ecol Epidemiol
|
2012
|
0.77
|
45
|
A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis.
|
Biopolymers
|
2013
|
0.77
|
46
|
An in vitro study on the DNA damaging effects of phytochemicals partially isolated from an extract of Glinus lotoides.
|
Phytother Res
|
2012
|
0.77
|
47
|
Genotoxicity and cellular uptake of cyclotides: evidence for multiple modes of action.
|
Mutat Res
|
2012
|
0.76
|
48
|
A cactus-derived toxin-like cystine knot Peptide with selective antimicrobial activity.
|
Chembiochem
|
2015
|
0.75
|
49
|
Affinity states of biocides determine bioavailability and release rates in marine paints.
|
Biofouling
|
2015
|
0.75
|