Published in Genes Dev on September 02, 2003
Mapping of long-range associations throughout the fission yeast genome reveals global genome organization linked to transcriptional regulation. Nucleic Acids Res (2010) 2.96
A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast. EMBO J (2004) 2.45
Kinetochore and heterochromatin domains of the fission yeast centromere. Chromosome Res (2004) 1.85
Centromeric localization of dispersed Pol III genes in fission yeast. Mol Biol Cell (2009) 1.60
A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology. PLoS Pathog (2010) 1.55
A two-step model for senescence triggered by a single critically short telomere. Nat Cell Biol (2009) 1.51
Length regulation and dynamics of individual telomere tracts in wild-type Arabidopsis. Plant Cell (2004) 1.34
Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect. Genes Dev (2004) 1.30
RNA interference (RNAi)-dependent and RNAi-independent association of the Chp1 chromodomain protein with distinct heterochromatic loci in fission yeast. Mol Cell Biol (2005) 1.24
Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. Nucleic Acids Res (2006) 1.23
Subtelomeric proteins negatively regulate telomere elongation in budding yeast. EMBO J (2006) 1.11
Telomeres in evolution and evolution of telomeres. Chromosome Res (2005) 1.06
Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+. Genetics (2004) 1.06
Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing. Mol Cell Biol (2005) 1.01
Centromeres were derived from telomeres during the evolution of the eukaryotic chromosome. Proc Natl Acad Sci U S A (2007) 0.99
Telomere regulation and function during meiosis. Chromosome Res (2007) 0.97
Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast. Nucleic Acids Res (2011) 0.95
Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres. Mol Biol Cell (2004) 0.93
Centromeric motion facilitates the mobility of interphase genomic regions in fission yeast. J Cell Sci (2013) 0.85
The telomere bouquet regulates meiotic centromere assembly. Nat Cell Biol (2015) 0.85
A single internal telomere tract ensures meiotic spindle formation. EMBO Rep (2013) 0.84
Involvement of condensin-directed gene associations in the organization and regulation of chromosome territories during the cell cycle. Nucleic Acids Res (2015) 0.79
Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing. Nat Commun (2016) 0.77
An IF-FISH Approach for Covisualization of Gene Loci and Nuclear Architecture in Fission Yeast. Methods Enzymol (2016) 0.75
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Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05
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Establishment and maintenance of a heterochromatin domain. Science (2002) 9.34
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev (1997) 7.81
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Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev (1995) 4.52
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The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability. J Cell Biol (1995) 4.10
Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell (1997) 3.72
Telomere-led premeiotic chromosome movement in fission yeast. Science (1994) 3.70
Position effect variegation at fission yeast centromeres. Cell (1994) 3.51
The chromodomain protein Swi6: a key component at fission yeast centromeres. Science (1995) 3.40
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Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell (1997) 2.88
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A bouquet makes ends meet. Nat Rev Mol Cell Biol (2001) 2.79
Circular chromosome formation in a fission yeast mutant defective in two ATM homologues. Nat Genet (1998) 2.71
spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr Biol (2001) 2.64
Two modes of survival of fission yeast without telomerase. Science (1998) 2.57
The complex structure and dynamic evolution of human subtelomeres. Nat Rev Genet (2002) 2.57
Chromosomal inheritance of epigenetic states in fission yeast during mitosis and meiosis. Cell (1996) 2.31
Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes. EMBO J (1994) 2.31
A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis. Cell (2000) 2.13
General purpose tagging vectors for fission yeast. Gene (1997) 2.10
A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast. Genetics (1997) 2.02
Dynamics of chromosome organization and pairing during meiotic prophase in fission yeast. J Cell Biol (1994) 1.91
Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Curr Biol (2001) 1.89
Telomere directed fragmentation of mammalian chromosomes. Nucleic Acids Res (1993) 1.88
Telomere-led bouquet formation facilitates homologous chromosome pairing and restricts ectopic interaction in fission yeast meiosis. EMBO J (2000) 1.73
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A novel fission yeast gene, kms1+, is required for the formation of meiotic prophase-specific nuclear architecture. Mol Gen Genet (1997) 1.66
Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.48
Meiotic telomeres: a matchmaker for homologous chromosomes. Genes Cells (1998) 1.20
Characterization of terminal deletions at 7q32 and 22q13.3 healed by De novo telomere addition. Am J Hum Genet (2000) 1.17
Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences. Nucleic Acids Res (1999) 1.02
Sequence-specific binding of Taz1p dimers to fission yeast telomeric DNA. Nucleic Acids Res (2000) 1.02
Why do we have linear chromosomes? A matter of Adam and Eve. Mutat Res (1999) 0.92
Telomere transitions in yeast: the end of the chromosome as we know it. Curr Opin Genet Dev (2000) 0.89
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells (2006) 5.68
Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem (2004) 3.73
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science (2008) 2.97
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol Cell (2009) 2.93
A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity (2004) 2.54
Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells (2003) 2.28
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression. Biochem Biophys Res Commun (2003) 2.27
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat Cell Biol (2008) 2.04
Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol (2005) 2.02
The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev (2008) 1.82
The CD8alpha gene locus is regulated by the Ikaros family of proteins. Mol Cell (2002) 1.79
The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2. J Biol Chem (2002) 1.74
RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation. Genes Cells (2007) 1.71
Loss of linker histone H1 in cellular senescence. J Cell Biol (2006) 1.71
Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation. Curr Biol (2012) 1.53
Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats. Nucleic Acids Res (2004) 1.53
Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body. J Biol Chem (2004) 1.49
Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D. J Biol Chem (2005) 1.38
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest (2007) 1.36
Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity (2010) 1.35
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature (2013) 1.35
Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract. J Biol Chem (2011) 1.29
Unusual telomeric DNAs in human telomerase-negative immortalized cells. Mol Cell Biol (2008) 1.29
Cellular senescence and chromatin structure. Chromosoma (2007) 1.26
Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast. Genes Dev (2012) 1.15
Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells. Mol Cell Biol (2011) 1.14
Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase. Mol Cell Biol (2009) 1.13
Tel2 is required for activation of the Mrc1-mediated replication checkpoint. J Biol Chem (2006) 1.10
MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase. J Biol Chem (2002) 1.08
Cohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activation. J Biol Chem (2002) 1.03
Alternative lengthening of telomeres pathway: recombination-mediated telomere maintenance mechanism in human cells. J Biochem (2010) 1.02
Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs. Biochem Biophys Res Commun (2002) 1.00
The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway. J Mol Biol (2003) 0.98
Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast. J Biol Chem (2002) 0.97
Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha. Mol Cell Biol (2005) 0.97
Transcriptional regulation of the Ikzf1 locus. Blood (2013) 0.97
Transcription-induced chromatin association of RNA surveillance factors mediates facultative heterochromatin formation in fission yeast. Genes Cells (2013) 0.96
Molecular mechanisms of DNA end-loop formation by TRF2. Genes Cells (2004) 0.95
Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice. Mol Cell Biol (2002) 0.91
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. PLoS One (2012) 0.90
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development. J Immunol (2011) 0.89
Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomerase. FEBS Lett (2002) 0.88
Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. EMBO J (2006) 0.87
Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cells. J Biol Chem (2012) 0.86
Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus. EMBO J (2013) 0.86
ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence. Cancer Sci (2007) 0.85
Telomerase rescues the expression levels of keratinocyte growth factor and insulin-like growth factor-II in senescent human fibroblasts. Exp Cell Res (2002) 0.85
HIRA, a conserved histone chaperone, plays an essential role in low-dose stress response via transcriptional stimulation in fission yeast. J Biol Chem (2012) 0.83
Essential roles of Xenopus TRF2 in telomere end protection and replication. Genes Cells (2011) 0.82
Large defects of type I allergic response in telomerase reverse transcriptase knockout mice. J Leukoc Biol (2007) 0.81
Interaction between DNMT1 and DNA replication reactions in the SV40 in vitro replication system. Cancer Sci (2008) 0.80
Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance. Genes Cells (2010) 0.79
Kinetics of DNA replication and telomerase reaction at a single-seeded telomere in human cells. Genes Cells (2012) 0.79
Fission yeast Ku protein is required for recovery from DNA replication stress. Genes Cells (2009) 0.79
Timeless tunes: replicating happy endings. Cell Cycle (2012) 0.77
Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast. J Biol Chem (2013) 0.75
[Conserved telomeric-end structures among fission yeast and humans]. Tanpakushitsu Kakusan Koso (2008) 0.75
[Function of telomerase and heritable disease]. Tanpakushitsu Kakusan Koso (2003) 0.75
[Tumor-suppressing role of cellular senescence and chromatin structure]. Nihon Ronen Igakkai Zasshi (2007) 0.75
Stretch PCR assay. Methods Mol Biol (2002) 0.75
Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance. J Immunol (2016) 0.75
[Telomere maintenance by DNA damage sensor kinases, ATM and ATR]. Seikagaku (2014) 0.75
Cell-cycle-dependent regulation of telomere binding proteins: roles of Polo-like kinase. Cell Cycle (2006) 0.75
Ninth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 18-20 September, 2003. Cancer Sci (2004) 0.75
Tenth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 29 September-1 October 2005. Cancer Sci (2006) 0.75
Lewis Acid-Catalyzed Cyclization Reactions of Ethenetricarboxylates via Intramolecular Hydride Transfer. J Org Chem (2017) 0.75
[Molecular biology of aging]. Nihon Ronen Igakkai Zasshi (2004) 0.75
[Replicative stress in telomeres]. Tanpakushitsu Kakusan Koso (2006) 0.75
[Telomere dysfunction in cancer progression]. Rinsho Ketsueki (2012) 0.75