Published in Genes Cells on June 01, 2007
Regulation of alternative splicing by histone modifications. Science (2010) 7.98
Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases. Cold Spring Harb Symp Quant Biol (2011) 1.81
A role for mammalian Sin3 in permanent gene silencing. Mol Cell (2008) 1.59
Physical and functional HAT/HDAC interplay regulates protein acetylation balance. J Biomed Biotechnol (2010) 1.55
Jarid1b targets genes regulating development and is involved in neural differentiation. EMBO J (2011) 1.50
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes Dev (2010) 1.44
Physiological roles of class I HDAC complex and histone demethylase. J Biomed Biotechnol (2010) 1.33
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc Natl Acad Sci U S A (2011) 1.28
KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J (2011) 1.27
MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks. J Cell Sci (2010) 1.20
Histone demethylase retinoblastoma binding protein 2 is overexpressed in hepatocellular carcinoma and negatively regulated by hsa-miR-212. PLoS One (2013) 1.07
Sin3B expression is required for cellular senescence and is up-regulated upon oncogenic stress. Cancer Res (2009) 1.07
Histone demethylases and cancer. Adv Cancer Res (2009) 1.05
A novel mammalian complex containing Sin3B mitigates histone acetylation and RNA polymerase II progression within transcribed loci. Mol Cell Biol (2010) 1.03
PALB2: the hub of a network of tumor suppressors involved in DNA damage responses. Biochim Biophys Acta (2014) 1.01
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. Proc Natl Acad Sci U S A (2012) 0.99
Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4. Chromosome Res (2011) 0.98
Where splicing joins chromatin. Nucleus (2011) 0.98
Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma. Oncogene (2011) 0.98
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells. J Neurosci Res (2009) 0.94
Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions. J Biol Chem (2010) 0.91
Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing. PLoS Genet (2013) 0.90
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II. Proc Natl Acad Sci U S A (2012) 0.89
Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells. Oncotarget (2014) 0.88
Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders. Epigenomics (2015) 0.86
DAXX is a new AIRE-interacting protein. J Biol Chem (2010) 0.86
Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex. J Biol Chem (2014) 0.86
Emerging role of the MORF/MRG gene family in various biological processes, including aging. Ann N Y Acad Sci (2010) 0.85
Sequence requirements for combinatorial recognition of histone H3 by the MRG15 and Pf1 subunits of the Rpd3S/Sin3S corepressor complex. J Mol Biol (2012) 0.84
MRG15 activates the cdc2 promoter via histone acetylation in human cells. Exp Cell Res (2011) 0.82
Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor. Stem Cell Res (2011) 0.81
Histone demethylases in chromatin biology and beyond. EMBO Rep (2015) 0.81
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3. Epigenetics Chromatin (2016) 0.80
EBNA3C Directs Recruitment of RBPJ (CBF1) to Chromatin during the Process of Gene Repression in EBV Infected B Cells. PLoS Pathog (2016) 0.79
Regulation of oncogene-induced cell cycle exit and senescence by chromatin modifiers. Cancer Biol Ther (2012) 0.78
Suppression of cryptic intragenic transcripts is required for embryonic stem cell self-renewal. EMBO J (2011) 0.78
Structural Basis for Multi-specificity of MRG Domains. Structure (2015) 0.77
MRG15 is required for pre-mRNA splicing and spermatogenesis. Proc Natl Acad Sci U S A (2016) 0.76
The epigenetics of germ-line immortality: lessons from an elegant model system. Dev Growth Differ (2010) 0.76
Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization. J Biol Chem (2014) 0.76
The chromatin associated Phf12 protein maintains nucleolar integrity and prevents premature cellular senescence. Mol Cell Biol (2016) 0.75
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair. PLoS One (2016) 0.75
A microdeletion at Xq22.2 implicates a glycine receptor GLRA4 involved in intellectual disability, behavioral problems and craniofacial anomalies. BMC Neurol (2016) 0.75
MRGBP as a potential biomarker for the malignancy of pancreatic ductal adenocarcinoma. Oncotarget (2017) 0.75
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells (2006) 5.68
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet (2003) 4.56
Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem (2004) 3.73
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science (2008) 2.97
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol Cell (2009) 2.93
A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell (2011) 2.58
Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells (2003) 2.28
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression. Biochem Biophys Res Commun (2003) 2.27
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat Cell Biol (2008) 2.04
Conserved ribonuclease, Eri1, negatively regulates heterochromatin assembly in fission yeast. Curr Biol (2006) 2.03
Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol (2005) 2.02
The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus. Nat Cell Biol (2009) 1.75
siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription. Mol Cell (2008) 1.74
The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2. J Biol Chem (2002) 1.74
Loss of linker histone H1 in cellular senescence. J Cell Biol (2006) 1.71
Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation. Curr Biol (2012) 1.53
Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats. Nucleic Acids Res (2004) 1.53
Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body. J Biol Chem (2004) 1.49
Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast. Mol Cell Biol (2008) 1.45
Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatic gene silencing. Mol Cell (2012) 1.42
Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D. J Biol Chem (2005) 1.38
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest (2007) 1.36
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature (2013) 1.35
Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract. J Biol Chem (2011) 1.29
hnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export. Science (2012) 1.29
Unusual telomeric DNAs in human telomerase-negative immortalized cells. Mol Cell Biol (2008) 1.29
Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats. Genes Dev (2003) 1.27
Cellular senescence and chromatin structure. Chromosoma (2007) 1.26
MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks. J Cell Sci (2010) 1.20
Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast. Genes Dev (2012) 1.15
Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells. Mol Cell Biol (2011) 1.14
Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase. Mol Cell Biol (2009) 1.13
Conversion of plasma membrane topology during epithelial tube connection requires Arf-like 3 small GTPase in Drosophila. Mech Dev (2007) 1.10
Tel2 is required for activation of the Mrc1-mediated replication checkpoint. J Biol Chem (2006) 1.10
Reconstitution of Arabidopsis thaliana SUMO pathways in E. coli: functional evaluation of SUMO machinery proteins and mapping of SUMOylation sites by mass spectrometry. Plant Cell Physiol (2009) 1.09
A conserved SET domain methyltransferase, Set11, modifies ribosomal protein Rpl12 in fission yeast. J Biol Chem (2008) 1.09
MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase. J Biol Chem (2002) 1.08
N-terminal phosphorylation of HP1{alpha} promotes its chromatin binding. Mol Cell Biol (2011) 1.04
Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin. Genes Dev (2009) 1.03
Cohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activation. J Biol Chem (2002) 1.03
Alternative lengthening of telomeres pathway: recombination-mediated telomere maintenance mechanism in human cells. J Biochem (2010) 1.02
Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs. Biochem Biophys Res Commun (2002) 1.00
The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway. J Mol Biol (2003) 0.98
IKKε regulates cell elongation through recycling endosome shuttling. Dev Cell (2011) 0.97
Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha. Mol Cell Biol (2005) 0.97
Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast. J Biol Chem (2002) 0.97
Transcription-induced chromatin association of RNA surveillance factors mediates facultative heterochromatin formation in fission yeast. Genes Cells (2013) 0.96
Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo. Mol Cancer Res (2013) 0.96
Gene expression and distribution of Swi6 in partial aneuploids of the fission yeast Schizosaccharomyces pombe. Cell Struct Funct (2007) 0.95
Molecular mechanisms of DNA end-loop formation by TRF2. Genes Cells (2004) 0.95
RNA and epigenetic silencing: insight from fission yeast. Dev Growth Differ (2011) 0.92
Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice. Mol Cell Biol (2002) 0.91
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. PLoS One (2012) 0.90
Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomerase. FEBS Lett (2002) 0.88
Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. EMBO J (2006) 0.87
Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cells. J Biol Chem (2012) 0.86
Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly. Proc Natl Acad Sci U S A (2012) 0.86
p54nrb/NonO and PSF promote U snRNA nuclear export by accelerating its export complex assembly. Nucleic Acids Res (2014) 0.85
Telomerase rescues the expression levels of keratinocyte growth factor and insulin-like growth factor-II in senescent human fibroblasts. Exp Cell Res (2002) 0.85
ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence. Cancer Sci (2007) 0.85
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity. J Biol Chem (2008) 0.84
HIRA, a conserved histone chaperone, plays an essential role in low-dose stress response via transcriptional stimulation in fission yeast. J Biol Chem (2012) 0.83
Genomic organization of zebra finch alpha and beta globin genes and their expression in primitive and definitive blood in comparison with globins in chicken. Dev Genes Evol (2009) 0.83
The WD40-repeat protein Pwp1p associates in vivo with 25S ribosomal chromatin in a histone H4 tail-dependent manner. Nucleic Acids Res (2006) 0.83
Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth. J Biol Chem (2010) 0.83
Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe. Mol Biol Cell (2006) 0.83
BetaA, the major beta globin in definitive red blood cells, is present from the onset of primitive erythropoiesis in chicken. Dev Dyn (2008) 0.82
Essential roles of Xenopus TRF2 in telomere end protection and replication. Genes Cells (2011) 0.82
Two different replication factor C proteins, Ctf18 and RFC1, separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV irradiation. Mol Cell Biol (2012) 0.82
Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing. J Biol Chem (2011) 0.81
Large defects of type I allergic response in telomerase reverse transcriptase knockout mice. J Leukoc Biol (2007) 0.81
C-terminus of the Sgf73 subunit of SAGA and SLIK is important for retention in the larger complex and for heterochromatin boundary function. Genes Cells (2013) 0.80
Interaction between DNMT1 and DNA replication reactions in the SV40 in vitro replication system. Cancer Sci (2008) 0.80
Fission yeast Ku protein is required for recovery from DNA replication stress. Genes Cells (2009) 0.79
Kinetics of DNA replication and telomerase reaction at a single-seeded telomere in human cells. Genes Cells (2012) 0.79
Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance. Genes Cells (2010) 0.79
Versatile strategy for isolating transcription activator-like effector nuclease-mediated knockout mutants in Caenorhabditis elegans. Dev Growth Differ (2013) 0.78
Fub1p, a novel protein isolated by boundary screening, binds the proteasome complex. Genes Genet Syst (2011) 0.78