Frank Eisenhaber

Author PubWeight™ 119.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 2004 8.58
2 The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends Biochem Sci 2003 5.19
3 The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates. Mol Cell 2005 2.77
4 TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Curr Biol 2003 2.71
5 Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. Genes Dev 2004 2.33
6 Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II. Curr Biol 2004 2.28
7 The STIR-domain superfamily in signal transduction, development and immunity. Trends Biochem Sci 2003 2.24
8 N-terminal N-myristoylation of proteins: prediction of substrate proteins from amino acid sequence. J Mol Biol 2002 2.18
9 A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces pombe. J Mol Biol 2004 2.09
10 Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. Curr Biol 2006 2.04
11 Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Curr Biol 2002 2.04
12 Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. Mol Cell 2003 1.85
13 Refinement and prediction of protein prenylation motifs. Genome Biol 2005 1.84
14 Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence. J Mol Biol 2003 1.83
15 Glycosylphosphatidylinositol lipid anchoring of plant proteins. Sensitive prediction from sequence- and genome-wide studies for Arabidopsis and rice. Plant Physiol 2003 1.72
16 N-terminal N-myristoylation of proteins: refinement of the sequence motif and its taxon-specific differences. J Mol Biol 2002 1.72
17 Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites. Biol Direct 2009 1.70
18 Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol 2005 1.65
19 The ring between ring fingers (RBR) protein family. Genome Biol 2007 1.59
20 Towards complete sets of farnesylated and geranylgeranylated proteins. PLoS Comput Biol 2007 1.57
21 Motif refinement of the peroxisomal targeting signal 1 and evaluation of taxon-specific differences. J Mol Biol 2003 1.51
22 Myristoylation of viral and bacterial proteins. Trends Microbiol 2004 1.49
23 pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model. Biol Direct 2007 1.46
24 Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins. Bioessays 2003 1.45
25 Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes. Proc Natl Acad Sci U S A 2004 1.43
26 MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins. Genome Biol 2004 1.42
27 TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter. Bioinformatics 2004 1.37
28 A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus. PLoS Curr 2010 1.37
29 On filtering false positive transmembrane protein predictions. Protein Eng 2002 1.35
30 RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells. J Cell Sci 2010 1.33
31 The highly pathogenic H7N3 avian influenza strain from July 2012 in Mexico acquired an extended cleavage site through recombination with host 28S rRNA. Virol J 2013 1.33
32 S. pombe meiotic linear elements contain proteins related to synaptonemal complex components. J Cell Sci 2004 1.31
33 Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 2005 1.29
34 More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology. PLoS Comput Biol 2010 1.26
35 ANNIE: integrated de novo protein sequence annotation. Nucleic Acids Res 2009 1.19
36 Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol 2005 1.16
37 Beware of moving targets: reference proteome content fluctuates substantially over the years. J Bioinform Comput Biol 2012 1.16
38 Extending Asia Pacific bioinformatics into new realms in the "-omics" era. BMC Genomics 2009 1.15
39 Protein prenyltransferases. Genome Biol 2003 1.11
40 SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. Nucleic Acids Res 2005 1.08
41 Posttranslational modifications and subcellular localization signals: indicators of sequence regions without inherent 3D structure? Curr Protein Pept Sci 2007 1.08
42 SUMO conjugation in plants. Planta 2004 1.07
43 Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. Cell Cycle 2008 1.06
44 Linking transcriptional mediators via the GACKIX domain super family. Curr Biol 2004 1.02
45 The substrate specificity profile of human granzyme A. Biol Chem 2010 0.98
46 Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics 2009 0.97
47 Synthesizing non-natural parts from natural genomic template. J Biol Eng 2009 0.95
48 Prediction of posttranslational modification of proteins from their amino acid sequence. Methods Mol Biol 2010 0.94
49 All that glitters is not gold--founder effects complicate associations of flu mutations to disease severity. Virol J 2010 0.93
50 Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7. J Biol Chem 2011 0.93
51 Prediction of sequence signals for lipid post-translational modifications: insights from case studies. Proteomics 2004 0.93
52 Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins. Biol Direct 2011 0.92
53 Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins. Genome Biol 2004 0.92
54 Protein prenyltransferases: anchor size, pseudogenes and parasites. Biol Chem 2003 0.92
55 Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo. BMC Biochem 2006 0.91
56 Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise. Proteomics 2006 0.88
57 Parameterization of disorder predictors for large-scale applications requiring high specificity by using an extended benchmark dataset. BMC Genomics 2010 0.88
58 Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases. BMC Bioinformatics 2006 0.87
59 On the necessity of different statistical treatment for Illumina BeadChip and Affymetrix GeneChip data and its significance for biological interpretation. Biol Direct 2008 0.87
60 Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ. Cell Mol Life Sci 2010 0.87
61 A new piece in the puzzle of the novel avian-origin influenza A (H7N9) virus. Biol Direct 2013 0.87
62 Nuclear import of a lipid-modified transcription factor: mobilization of NFAT5 isoform a by osmotic stress. Cell Cycle 2011 0.86
63 SPACER: Server for predicting allosteric communication and effects of regulation. Nucleic Acids Res 2013 0.86
64 A CH domain-containing N terminus in NuMA? Protein Sci 2002 0.85
65 Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress. Biochim Biophys Acta 2014 0.84
66 Biomolecular pathway databases. Methods Mol Biol 2010 0.84
67 Databases of protein-protein interactions and complexes. Methods Mol Biol 2010 0.83
68 Structural insight into the glycosylphosphatidylinositol transamidase subunits PIG-K and PIG-S from yeast. J Struct Biol 2010 0.83
69 Transmembrane helix: simple or complex. Nucleic Acids Res 2012 0.82
70 Induction of short interspersed nuclear repeat-containing transcripts in epithelial cells upon infection with a chicken adenovirus. J Mol Biol 2003 0.82
71 Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4. J Biol Chem 2009 0.82
72 The Janus-faced E-values of HMMER2: extreme value distribution or logistic function? J Bioinform Comput Biol 2011 0.81
73 Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction. BMC Genomics 2010 0.81
74 Novel SNP improves differential survivability and mortality in non-small cell lung cancer patients. BMC Genomics 2014 0.81
75 Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing. Biochem J 2011 0.80
76 Arxes: retrotransposed genes required for adipogenesis. Nucleic Acids Res 2010 0.80
77 On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation. BMC Bioinformatics 2014 0.80
78 Reannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenoviruses. BMC Bioinformatics 2003 0.80
79 Is LGI2 the candidate gene for partial epilepsy with pericentral spikes? J Bioinform Comput Biol 2010 0.79
80 Integrated tools for biomolecular sequence-based function prediction as exemplified by the ANNOTATOR software environment. Methods Mol Biol 2010 0.79
81 Investigation of causes of oseltamivir chemoprophylaxis failures during influenza A (H1N1-2009) outbreaks. J Clin Virol 2010 0.79
82 A simple shortcut to unsupervised alignment-free phylogenetic genome groupings, even from unassembled sequencing reads. J Bioinform Comput Biol 2013 0.79
83 Detecting atypical examples of known domain types by sequence similarity searching: the SBASE domain library approach. Curr Protein Pept Sci 2010 0.78
84 Potential human adaptation mutation of influenza A(H5N1) virus, Canada. Emerg Infect Dis 2014 0.78
85 Sporadic human cases of swine-origin influenza before 2009 share the Sa epitope. Cell Cycle 2010 0.78
86 PhyloDome--visualization of taxonomic distributions of domains occurring in eukaryote protein sequence sets. Nucleic Acids Res 2005 0.77
87 Low-resolution structure of the soluble domain GPAA1 (yGPAA170-247) of the glycosylphosphatidylinositol transamidase subunit GPAA1 from Saccharomyces cerevisiae. Biosci Rep 2013 0.77
88 Tachyon search speeds up retrieval of similar sequences by several orders of magnitude. Bioinformatics 2012 0.77
89 Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2. BMC Biochem 2010 0.76
90 DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity. Nucleic Acids Res 2006 0.76
91 International Conference on Genome Informatics (GIW 2013) in Singapore: Introduction to the systems biology contributions. BMC Syst Biol 2013 0.75
92 Purification and crystallization of yeast glycosylphosphatidylinositol transamidase subunit PIG-S (PIG-S(71-467)). Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.75
93 Motif discovery with data mining in 3D protein structure databases: discovery, validation and prediction of the U-shape zinc binding ("Huf-Zinc") motif. J Bioinform Comput Biol 2013 0.75
94 Guest Editorial for the International Conference on Genome Informatics (GIW 2013). IEEE/ACM Trans Comput Biol Bioinform 2015 0.75
95 Automatic phylogenetic classification of bacterial beta-lactamase sequences including structural and antibiotic substrate preference information. J Bioinform Comput Biol 2013 0.75