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1
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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus.
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N Engl J Med
|
2002
|
8.84
|
|
2
|
Diabetes and cancer: a consensus report.
|
Diabetes Care
|
2010
|
6.71
|
|
3
|
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.
|
J Histochem Cytochem
|
2005
|
4.40
|
|
4
|
A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes.
|
Diabetes
|
2005
|
4.19
|
|
5
|
Diabetes and cancer: a consensus report.
|
CA Cancer J Clin
|
2010
|
3.95
|
|
6
|
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.
|
Endocrinology
|
2003
|
3.93
|
|
7
|
Survival after pancreas transplantation in patients with diabetes and preserved kidney function.
|
JAMA
|
2003
|
3.33
|
|
8
|
Insulin secretion in type 1 diabetes.
|
Diabetes
|
2004
|
2.59
|
|
9
|
Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).
|
Transplantation
|
2003
|
2.48
|
|
10
|
Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes.
|
Diabetes Care
|
2009
|
2.02
|
|
11
|
Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway.
|
Endocrinology
|
2002
|
1.95
|
|
12
|
Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.
|
Diabetes Care
|
2003
|
1.86
|
|
13
|
Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes.
|
Diabetes
|
2014
|
1.81
|
|
14
|
Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes.
|
Diabetes Care
|
2013
|
1.81
|
|
15
|
Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.
|
Lancet
|
2002
|
1.76
|
|
16
|
Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus.
|
J Clin Invest
|
2004
|
1.50
|
|
17
|
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function.
|
J Biol Chem
|
2009
|
1.49
|
|
18
|
Ethnicity greatly influences cytokine gene polymorphism distribution.
|
Am J Transplant
|
2002
|
1.48
|
|
19
|
Ex vivo culture with human brain endothelial cells increases the SCID-repopulating capacity of adult human bone marrow.
|
Blood
|
2002
|
1.33
|
|
20
|
Pancreatic islet transplantation.
|
PLoS Med
|
2004
|
1.21
|
|
21
|
Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging.
|
Transplantation
|
2005
|
1.15
|
|
22
|
Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection.
|
Nat Biotechnol
|
2009
|
1.13
|
|
23
|
Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.
|
PLoS One
|
2009
|
1.11
|
|
24
|
Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance.
|
Mol Endocrinol
|
2004
|
1.10
|
|
25
|
Dynamic changes in pancreatic endocrine cell abundance, distribution, and function in antigen-induced and spontaneous autoimmune diabetes.
|
Diabetes
|
2009
|
1.10
|
|
26
|
Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes.
|
Diabetes Technol Ther
|
2011
|
1.07
|
|
27
|
A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets.
|
Endocrinology
|
2002
|
1.05
|
|
28
|
Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.
|
PLoS One
|
2009
|
0.99
|
|
29
|
T cell-directed therapies: lessons learned and future prospects.
|
Nat Immunol
|
2007
|
0.98
|
|
30
|
Resistin is expressed in pancreatic islets.
|
Biochem Biophys Res Commun
|
2003
|
0.97
|
|
31
|
Differences in the management of type 1 diabetes among adults under excellent control compared with those under poor control in the T1D Exchange Clinic Registry.
|
Diabetes Care
|
2013
|
0.97
|
|
32
|
Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site.
|
Diabetes
|
2002
|
0.96
|
|
33
|
Disruption of CD40/CD40-ligand interactions in a retinal autoimmunity model results in protection without tolerance.
|
J Immunol
|
2005
|
0.96
|
|
34
|
Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation.
|
J Transl Med
|
2007
|
0.94
|
|
35
|
Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation.
|
J Immunol
|
2003
|
0.94
|
|
36
|
The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge.
|
Int Immunol
|
2004
|
0.93
|
|
37
|
Insulinomas and expression of an insulin splice variant.
|
Lancet
|
2004
|
0.93
|
|
38
|
Humanized mice for the study of type 1 and type 2 diabetes.
|
Ann N Y Acad Sci
|
2011
|
0.92
|
|
39
|
Extrapancreatic autoantibody profiles in type I diabetes.
|
PLoS One
|
2012
|
0.88
|
|
40
|
Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model.
|
Am J Transplant
|
2002
|
0.87
|
|
41
|
Combination induction therapy with monoclonal antibodies specific for CD80, CD86, and CD154 in nonhuman primate renal transplantation.
|
Transplantation
|
2002
|
0.87
|
|
42
|
Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression.
|
J Clin Endocrinol Metab
|
2002
|
0.85
|
|
43
|
Induction of diabetes in nonhuman primates by means of temporary arterial embolization and selective arterial injection of streptozotocin.
|
Radiology
|
2004
|
0.85
|
|
44
|
Sirolimus-induced interstitial pneumonitis in an islet transplant recipient.
|
Diabetes Care
|
2003
|
0.84
|
|
45
|
Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes.
|
Diabetes Care
|
2009
|
0.84
|
|
46
|
Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates.
|
Transplantation
|
2002
|
0.84
|
|
47
|
Counterpoint: clinical islet transplantation: not ready for prime time.
|
Diabetes Care
|
2009
|
0.83
|
|
48
|
Beta cell-specific CD80 (B7-1) expression disrupts tissue protection from autoantigen-specific CTL-mediated diabetes.
|
J Autoimmun
|
2003
|
0.83
|
|
49
|
Immune intervention with anti-CD3 in diabetes.
|
Nat Med
|
2005
|
0.83
|
|
50
|
Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.
|
Transplantation
|
2003
|
0.82
|
|
51
|
Assessment of islet function following islet and pancreas transplantation.
|
Curr Diab Rep
|
2006
|
0.81
|
|
52
|
Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy.
|
Cell Transplant
|
2011
|
0.81
|
|
53
|
Islet transplantation: where do we stand now?
|
Diabetes Metab Res Rev
|
2003
|
0.81
|
|
54
|
Effects of combined treatment with CD25- and CD154-specific monoclonal antibodies in non-human primate allotransplantation.
|
Am J Transplant
|
2003
|
0.80
|
|
55
|
Islet transplantation as a treatment for diabetes.
|
N Engl J Med
|
2004
|
0.80
|
|
56
|
State of the art: islet transplantation for the cure of type 1 diabetes mellitus.
|
Rev Endocr Metab Disord
|
2003
|
0.80
|
|
57
|
Resistin serum levels in type 1 diabetes pre- and post-islet transplantation.
|
Metabolism
|
2004
|
0.78
|
|
58
|
Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors.
|
Virol J
|
2009
|
0.78
|
|
59
|
Pulmonary angiography for the diagnosis of thromboembolic events in the non-human primate.
|
Transplantation
|
2004
|
0.78
|
|
60
|
Islet neogenesis associated protein transgenic mice are resistant to hyperglycemia induced by streptozotocin.
|
J Endocrinol
|
2006
|
0.77
|
|
61
|
Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity.
|
Ann N Y Acad Sci
|
2007
|
0.77
|
|
62
|
The pancreatic β-cell transcriptome and integrated-omics.
|
Curr Opin Endocrinol Diabetes Obes
|
2014
|
0.76
|
|
63
|
Infant formula, autoimmune triggers, and type 1 diabetes.
|
N Engl J Med
|
2010
|
0.75
|
|
64
|
Comment on: Keenan et al. (2010) residual insulin production and pancreatic ß-Cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes 2010;59:2846-2853.
|
Diabetes
|
2010
|
0.75
|
|
65
|
Corrigendum: Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
|
Nat Biotechnol
|
2016
|
0.75
|
|
66
|
The Clinical Center's blood glucose management service: a story in quality integrated care.
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Diabetes Educ
|
2011
|
0.75
|
|
67
|
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
|
Nat Med
|
2017
|
0.75
|
|
68
|
Diabetes: 8 strategies to put into practice.
|
J Fam Pract
|
2013
|
0.75
|
|
69
|
Islet transplantation and the challenges of treating type 1 diabetes.
|
Discov Med
|
2005
|
0.75
|
|
70
|
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
|
Nat Med
|
2017
|
0.75
|