Published in J Bacteriol on April 01, 1992
Untwist and shout: a heavy metal-responsive transcriptional regulator. J Bacteriol (1992) 2.49
Bioluminescent sensors for detection of bioavailable Hg(II) in the environment. Appl Environ Microbiol (1993) 2.27
Where microbiology meets microengineering: design and applications of reporter bacteria. Nat Rev Microbiol (2010) 1.66
Comparative genomics of regulation of fatty acid and branched-chain amino acid utilization in proteobacteria. J Bacteriol (2008) 1.45
Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR. J Bacteriol (1999) 0.97
Mutations in the alpha and sigma-70 subunits of RNA polymerase affect expression of the mer operon. J Bacteriol (1997) 0.91
Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. J Bacteriol (2010) 0.89
Mercury resistance in Bacillus cereus RC607: transcriptional organization and two new open reading frames. J Bacteriol (1999) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene (1985) 213.67
Compilation and analysis of Escherichia coli promoter DNA sequences. Nucleic Acids Res (1983) 38.72
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res (1981) 24.41
Analysis of E. coli promoter sequences. Nucleic Acids Res (1987) 14.12
Mechanism and control of transcription initiation in prokaryotes. Annu Rev Biochem (1985) 11.99
Protein-nucleic acid interactions in transcription: a molecular analysis. Annu Rev Biochem (1984) 8.31
DNA recognition by proteins with the helix-turn-helix motif. Annu Rev Biochem (1990) 5.56
Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein. Mol Cell Biol (1989) 5.23
A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site. Proc Natl Acad Sci U S A (1985) 4.01
The molecular basis of DNA-protein recognition inferred from the structure of cro repressor. Nature (1982) 3.56
Stringent spacing requirements for transcription activation by CRP. Cell (1990) 3.52
Functional dissection of Escherichia coli promoters: information in the transcribed region is involved in late steps of the overall process. EMBO J (1986) 3.33
The three-dimensional structure of trp repressor. Nature (1985) 3.26
The MerR heavy metal receptor mediates positive activation in a topologically novel transcription complex. Cell (1989) 3.18
A simple and efficient procedure for saturation mutagenesis using mixed oligodeoxynucleotides. Gene (1986) 2.99
Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes. EMBO J (1989) 2.98
Organization, expression, and evolution of genes for mercury resistance. Annu Rev Microbiol (1986) 2.88
Overlapping divergent promoters control expression of Tn10 tetracycline resistance. Gene (1983) 2.85
Analysis of the sequence-specific interactions between Cro repressor and operator DNA by systematic base substitution experiments. Proc Natl Acad Sci U S A (1989) 2.76
Promoter-probe vectors for the analysis of divergently arranged promoters. Gene (1986) 2.73
Lambda repressor recognizes the approximately 2-fold symmetric half-operator sequences asymmetrically. Proc Natl Acad Sci U S A (1989) 2.61
Linker tailing: unphosphorylated linker oligonucleotides for joining DNA termini. DNA (1984) 2.56
Cloning and DNA sequence of the mercuric- and organomercurial-resistance determinants of plasmid pDU1358. Proc Natl Acad Sci U S A (1987) 2.48
Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes. Proc Natl Acad Sci U S A (1984) 2.45
The nucleotide sequence of the mercuric resistance operons of plasmid R100 and transposon Tn501: further evidence for mer genes which enhance the activity of the mercuric ion detoxification system. Mol Gen Genet (1986) 2.34
Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1. J Bacteriol (1979) 2.33
DNA-binding site of lac repressor probed by dimethylsulfate methylation of lac operator. J Mol Biol (1979) 2.20
Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites. Mol Cell Biol (1990) 2.00
Nucleotide sequence and expression of the mercurial-resistance operon from Staphylococcus aureus plasmid pI258. Proc Natl Acad Sci U S A (1987) 1.99
The DNA sequence of the mercury resistance operon of the IncFII plasmid NR1. J Mol Appl Genet (1984) 1.98
Tn5 insertion mutations in the mercuric ion resistance genes derived from plasmid R100. J Bacteriol (1983) 1.94
Hierarchies of base pair preferences in the P22 ant promoter. J Bacteriol (1991) 1.89
The MerR metalloregulatory protein binds mercuric ion as a tricoordinate, metal-bridged dimer. Science (1990) 1.76
Metalloregulatory DNA-binding protein encoded by the merR gene: isolation and characterization. Science (1987) 1.70
Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex. Proc Natl Acad Sci U S A (1990) 1.63
Genetic analysis of transcriptional activation and repression in the Tn21 mer operon. J Bacteriol (1989) 1.62
DNA distortion accompanies transcriptional activation by the metal-responsive gene-regulatory protein MerR. Biochemistry (1990) 1.57
Transcriptional regulation of the mercury-resistance genes of transposon Tn501. J Gen Microbiol (1986) 1.56
How Trp repressor binds to its operator. EMBO J (1990) 1.53
Conserved residues make similar contacts in two repressor-operator complexes. Science (1990) 1.48
Homologous metalloregulatory proteins from both gram-positive and gram-negative bacteria control transcription of mercury resistance operons. J Bacteriol (1989) 1.46
Promoter recognition by Escherichia coli RNA polymerase. Effects of substitutions in the spacer DNA separating the -10 and -35 regions. J Biol Chem (1986) 1.46
Ultrasensitivity and heavy-metal selectivity of the allosterically modulated MerR transcription complex. Proc Natl Acad Sci U S A (1990) 1.45
Purification and functional characterization of MerD. A coregulator of the mercury resistance operon in gram-negative bacteria. J Biol Chem (1991) 1.39
Activator-dependent preinduction binding of sigma-70 RNA polymerase at the metal-regulated mer promoter. Biochemistry (1990) 1.34
Site-specific insertion and deletion mutants in the mer promoter-operator region of Tn501; the nineteen base-pair spacer is essential for normal induction of the promoter by MerR. Nucleic Acids Res (1990) 1.29
Cadmium- and mercury-resistant Bacillus strains from a salt marsh and from Boston Harbor. Appl Environ Microbiol (1986) 1.24
Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving. Science (1990) 1.23
Regulation of transcription in Escherichia coli from the mer and merR promoters in the transposon Tn501. J Mol Biol (1989) 1.21
Control of transcription by the bacteriophage P22 repressor. J Mol Biol (1982) 1.21
Overexpression and DNA-binding properties of the mer-encoded regulatory protein from plasmid NR1 (Tn21). J Bacteriol (1987) 1.20
Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury(II) binding domains. Biochemistry (1989) 1.19
Saturation mutagenesis of the Tn10-encoded tet operator O1. Identification of base-pairs involved in Tet repressor recognition. J Mol Biol (1988) 1.14
Transcriptional switching by the metalloregulatory MerR protein: initial characterization of DNA and mercury (II) binding activities. Biochemistry (1989) 1.08
An NMR-based molecular dynamics simulation of the interaction of the lac repressor headpiece and its operator in aqueous solution. Proteins (1989) 0.86
Symmetric lac operator derivatives: effects of half-operator sequence and spacing on repressor affinity. Gene (1990) 0.86
Transposon Tn21, flagship of the floating genome. Microbiol Mol Biol Rev (1999) 4.65
Microbial transformations of metals. Annu Rev Microbiol (1978) 4.31
Mercury resistance in a plasmid-bearing strain of Escherichia coli. J Bacteriol (1972) 3.93
Plasmid-determined resistance to tellurium compounds. J Bacteriol (1977) 3.56
Organization, expression, and evolution of genes for mercury resistance. Annu Rev Microbiol (1986) 2.88
Outer membrane proteins of Escherichia coli. V. Evidence that protein 1 and bacteriophage-directed protein 2 are different polypeptides. J Bacteriol (1977) 2.57
Mercury released from dental "silver" fillings provokes an increase in mercury- and antibiotic-resistant bacteria in oral and intestinal floras of primates. Antimicrob Agents Chemother (1993) 2.40
Incidence and characterization of integrons, genetic elements mediating multiple-drug resistance, in avian Escherichia coli. Antimicrob Agents Chemother (1999) 2.27
Volatilization of mercuric chloride by mercury-resistant plasmid-bearing strains of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. J Bacteriol (1973) 2.23
The DNA sequence of the mercury resistance operon of the IncFII plasmid NR1. J Mol Appl Genet (1984) 1.98
Mercury exposure from "silver" tooth fillings: emerging evidence questions a traditional dental paradigm. FASEB J (1995) 1.94
Incidence of class 1 and 2 integrases in clinical and commensal bacteria from livestock, companion animals, and exotics. Antimicrob Agents Chemother (2001) 1.88
Rubrerythrin and rubredoxin oxidoreductase in Desulfovibrio vulgaris: a novel oxidative stress protection system. J Bacteriol (2001) 1.84
Cell-free mercury(II)-reducing activity in a plasmid-bearing strain of Escherichia coli. J Bacteriol (1974) 1.66
Polypeptides encoded by the mer operon. J Bacteriol (1982) 1.65
Genetic analysis of transcriptional activation and repression in the Tn21 mer operon. J Bacteriol (1989) 1.62
Plasmid-determined resistance to boron and chromium compounds in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1978) 1.58
Reduction in Legionella pneumophila through heat flushing followed by continuous supplemental chlorination of hospital hot water. J Infect Dis (1990) 1.51
Production of highly labeled adenoviruses. Appl Microbiol (1968) 1.50
A mer-lux transcriptional fusion for real-time examination of in vivo gene expression kinetics and promoter response to altered superhelicity. J Bacteriol (1992) 1.43
Phylogeny of mercury resistance (mer) operons of gram-negative bacteria isolated from the fecal flora of primates. Appl Environ Microbiol (1997) 1.38
Activator-dependent preinduction binding of sigma-70 RNA polymerase at the metal-regulated mer promoter. Biochemistry (1990) 1.34
The distribution and divergence of DNA sequences related to the Tn21 and Tn501 mer operons. Plasmid (1988) 1.32
Association of mercury resistance with antibiotic resistance in the gram-negative fecal bacteria of primates. Appl Environ Microbiol (1997) 1.30
Association of tellurium resistance and bacteriophage inhibition conferred by R plasmids. J Bacteriol (1979) 1.29
Roles of the Tn21 merT, merP, and merC gene products in mercury resistance and mercury binding. J Bacteriol (1992) 1.29
Wide-host-range plasmids function in the genus thiobacillus. Appl Environ Microbiol (1983) 1.25
Versatile mercury-resistant cloning and expression vectors. Gene (1985) 1.21
Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100. J Bacteriol (1982) 1.20
Overexpression and DNA-binding properties of the mer-encoded regulatory protein from plasmid NR1 (Tn21). J Bacteriol (1987) 1.20
Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury(II) binding domains. Biochemistry (1989) 1.19
Mercuric ion reduction and resistance in transgenic Arabidopsis thaliana plants expressing a modified bacterial merA gene. Proc Natl Acad Sci U S A (1996) 1.18
Physical and genetic map of the organomercury resistance (Omr) and inorganic mercury resistance (Hgr) loci of the IncM plasmid R831b. Gene (1984) 1.09
A second positive regulatory function in the mer (mercury resistance) operon. Gene (1983) 1.02
Transposition of mercury resistance from a transferable R plasmic of Escherichia coli. Plasmid (1980) 1.02
Tn1 generated mutants in the mercuric ion reductase of the Inc P plasmid, R702. Mol Gen Genet (1980) 1.01
Translation of merD in Tn21. J Bacteriol (1989) 0.99
Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR. J Bacteriol (1999) 0.97
MerR cross-links to the alpha, beta, and sigma 70 subunits of RNA polymerase in the preinitiation complex at the merTPCAD promoter. Biochemistry (1999) 0.97
Transpositional Mutagenesis of Thiobacillus novellus and Thiobacillus versutus. Appl Environ Microbiol (1985) 0.96
Synthesis and degradation of the mRNA of the Tn21 mer operon. J Mol Biol (1992) 0.95
The core metal-recognition domain of MerR. Biochemistry (1998) 0.95
A rubrerythrin operon and nigerythrin gene in Desulfovibrio vulgaris (Hildenborough). J Bacteriol (1997) 0.95
In vivo DNA-protein interactions at the divergent mercury resistance (mer) promoters. I. Metalloregulatory protein MerR mutants. J Biol Chem (1993) 0.95
Phytoremediation of methylmercury pollution: merB expression in Arabidopsis thaliana confers resistance to organomercurials. Proc Natl Acad Sci U S A (1999) 0.95
Mutations in the alpha and sigma-70 subunits of RNA polymerase affect expression of the mer operon. J Bacteriol (1997) 0.91
Developmental induction of Myxococcus xanthus myxospores. J Bacteriol (1979) 0.90
Cloning a promoter that puts the expression of tetracycline resistance under the control of the regulatory elements of the mer operon. Gene (1981) 0.88
Bacterial oxidation of mercury metal vapor, Hg(0). Appl Environ Microbiol (1998) 0.87
The structure of the mer operon. Basic Life Sci (1985) 0.86
Effect of catabolite repression on the mer operon. J Bacteriol (1982) 0.86
From genotype to phenotype: computer-based modeling of gene expression with STELLA II. Biotechniques (1993) 0.83
The quality of merC, a module of the mer mosaic. J Mol Evol (2000) 0.82
A glutamate uptake regulatory protein (Grp) in Escherichia coli? Mol Microbiol (1997) 0.81
In vivo DNA-protein interactions at the divergent mercury resistance (mer) promoters. II. Repressor/activator (MerR)-RNA polymerase interaction with merOP mutants. J Biol Chem (1993) 0.81
The impact of mercury released from dental "silver" fillings on antibiotic resistances in the primate oral and intestinal bacterial flora. Met Ions Biol Syst (1997) 0.81
Near-zero background cloning of PCR products. Biotechniques (1997) 0.76
The dental amalgam mercury controversy--inorganic mercury and the CNS; genetic linkage of mercury and antibiotic resistances in intestinal bacteria. Toxicology (1995) 0.76
New policy for titles of letters to the editor. Antimicrob Agents Chemother (1994) 0.75