Published in J Biol Chem on April 05, 1992
Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell Biol (1994) 2.12
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Natl Acad Sci U S A (1994) 1.77
Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem J (1992) 1.57
A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities. EMBO J (1995) 1.53
Regulation of cell structure and function by actin-binding proteins: villin's perspective. FEBS Lett (2008) 1.40
Effects of CapG overexpression on agonist-induced motility and second messenger generation. J Cell Biol (1995) 1.19
Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach. Protein Sci (1999) 1.16
Gelsolin modulates phospholipase C activity in vivo through phospholipid binding. J Cell Biol (1997) 1.05
Activation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates. Biochem J (1993) 1.03
Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines. Open Neurosci J (2009) 0.99
Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10. Br J Cancer (2003) 0.89
Role and regulation of sperm gelsolin prior to fertilization. J Biol Chem (2010) 0.85
Potentiation by cholera toxin of bradykinin-induced inositol phosphate production in the osteoblast-like cell line MC3T3-E1. Biochem J (1993) 0.84
Thrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cgamma1. Biochem J (1997) 0.80
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem (1993) 3.88
Pathology of hepatocellular carcinoma in Japan. 232 Consecutive cases autopsied in ten years. Cancer (1983) 3.28
Evidence implicating phospholipase as a virulence factor of Candida albicans. Infect Immun (1995) 2.75
Postexposure prophylaxis of varicella in family contact by oral acyclovir. Pediatrics (1993) 2.67
Comparison of aminoglycoside resistance patterns in Japan, Formosa, and Korea, Chile, and the United States. Antimicrob Agents Chemother (1985) 2.66
Characteristics of Ca2+- and Mg2+-induced tension development in chemically skinned smooth muscle fibers. J Gen Physiol (1978) 2.29
Biochemical characterization and biologic actions of two toxins (D-1 and D-2) from Clostridium difficile. Rev Infect Dis (1984) 2.26
Connectin, an elastic protein of muscle. Characterization and Function. J Biochem (1977) 2.14
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Invest (1999) 2.09
Cloning and disruption of caPLB1, a phospholipase B gene involved in the pathogenicity of Candida albicans. J Biol Chem (1998) 1.84
Hepatocellular carcinoma presenting as intrabile duct tumor growth: a clinicopathologic study of 24 cases. Cancer (1982) 1.80
Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells. Proc Natl Acad Sci U S A (1995) 1.79
In-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents. J Antimicrob Chemother (1985) 1.78
A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms. Lab Invest (1997) 1.74
Hepatocellular carcinoma with sarcomatous change. Clinicopathologic and immunohistochemical studies of 14 autopsy cases. Cancer (1987) 1.73
Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts. J Lab Clin Med (1999) 1.73
Molecular control of membrane properties during temperature acclimation. Fatty acid desaturase regulation of membrane fluidity in acclimating Tetrahymena cells. Biochemistry (1976) 1.72
The tumour-stromal interaction between intratumoral c-Met and stromal hepatocyte growth factor associated with tumour growth and prognosis in non-small-cell lung cancer patients. Br J Cancer (2004) 1.71
Simple and rapid purification of brevin. Biochem Biophys Res Commun (1990) 1.70
Periodic distribution of troponin along the thin filament. J Biochem (1967) 1.69
Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress. Leukemia (2010) 1.64
Retracted Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation. Circ Res (2001) 1.64
Increased activity and intranuclear expression of phospholipase D2 in human renal cancer. Biochem Biophys Res Commun (2000) 1.64
A method that preserves circulation during preparation of the pectoralis major myocutaneous flap in head and neck reconstruction. Plast Reconstr Surg (1998) 1.63
Functional characterization of the recombinant type 3 Ca2+ release channel (ryanodine receptor) expressed in HEK293 cells. J Biol Chem (1997) 1.61
A novel role for interleukin-18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseases. Arthritis Rheum (2001) 1.57
Clinical analysis of a series of vertebral aneurysm cases. Neurosurgery (1992) 1.57
Assessment of transesophageal Doppler echography in dissecting aortic aneurysm. J Am Coll Cardiol (1989) 1.56
Clinical and virological analyses of 21 infants with exanthem subitum (roseola infantum) and central nervous system complications. Ann Neurol (1993) 1.55
Myosin II is involved in transmitter release at synapses formed between rat sympathetic neurons in culture. Neuron (1994) 1.52
Bacterial and crystal adherence to the surfaces of indwelling urethral catheters. J Urol (1990) 1.52
Tetrodotoxin and manganese ions: effects on electrical activity and tension in taenia coli of guinea pig. Science (1966) 1.50
Importance of left atrial function in patients with myocardial infarction. Circulation (1983) 1.46
Importance of left ventricular systolic function in the assessment of left ventricular diastolic function with Doppler transmitral flow velocity recording. J Am Coll Cardiol (1991) 1.46
HLA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression. Dig Dis Sci (1995) 1.45
New disease-modifying antirheumatic drug 2 acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid (KE-298) selectively augments activation-induced T cell death. J Lab Clin Med (2001) 1.42
Molecular identification of the ryanodine receptor Ca2+ sensor. J Biol Chem (1998) 1.41
Accumulation of diacylgylcerol in platelet phosphoinositide turnover in schizophrenia: a biological marker of good prognosis? Biol Psychiatry (1989) 1.41
Hepatocellular carcinoma with intra-atrial tumor growth. A clinicopathologic study of 18 autopsy cases. Arch Pathol Lab Med (1984) 1.40
Retreatment of chronic hepatitis C with interferon. Am J Gastroenterol (1994) 1.39
Significance of early measurement of serum hepatitis C virus RNA in predicting response to interferon therapy in patients with chronic hepatitis C. Eur J Gastroenterol Hepatol (1997) 1.39
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. J Immunol (2001) 1.37
Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. J Clin Invest (1998) 1.37
The amino acid sequence of Clostridium pasteurianum ferredoxin. Biochemistry (1966) 1.37
Bradykinin-induced rapid breakdown of phosphatidylinositol 4,5-bisphosphate in neuroblastoma X glioma hybrid NG108-15 cells. J Biol Chem (1984) 1.36
Freeze-fracture ultrastructural alterations induced by filipin, pimaricin, nystatin and amphotericin B in the plasmia membranes of Epidermophyton, Saccharomyces and red complex-induced membrane lesions. Biochim Biophys Acta (1976) 1.34
The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells. J Biol Chem (1988) 1.34
Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of Lens culinaris agglutinin-reactive alpha-fetoprotein. J Gastroenterol Hepatol (2001) 1.33
Pathologic characteristics of hepatocellular carcinoma. Semin Liver Dis (1986) 1.32
Structure of liver ribosomes studied by negative staining. J Mol Biol (1971) 1.32
Normal bronchial mucus contains high levels of cancer-associated antigens, CA125, CA19-9, and carcinoembryonic antigen. Cancer (1990) 1.32
Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection. J Hepatol (2000) 1.32
Hepatocellular carcinoma without cirrhosis in Japanese patients. Gastroenterology (1989) 1.31
Why is the interferon sensitivity-determining region (ISDR) system useful in Japan? J Hepatol (1999) 1.31
Smoking and drinking habits as risk factors for hearing loss in the elderly: epidemiological study of subjects undergoing routine health checks in Aichi, Japan. Public Health (2001) 1.30
Human herpesvirus-6 DNA in cerebrospinal fluid of a child with exanthem subitum and meningoencephalitis. Pediatrics (1992) 1.29
The amino acid sequence of the Tetrahymena calmodulin which specifically interacts with guanylate cyclase. Biochem Biophys Res Commun (1981) 1.27
Involvement of an acidic protein in regulation of smooth muscle contraction by the tropomyosin-leiotonin system. J Biochem (1978) 1.25
Human herpesvirus-6 infection in bone marrow transplantation. Blood (1991) 1.25
Multiple occurrence of carcinoma in the upper aerodigestive tract associated with esophageal cancer: reference to smoking, drinking and family history. Int J Cancer (1994) 1.25
Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum). Pediatrics (1994) 1.24
Ca2+-dependent modulator proteins from Tetrahymena pyriformis, sea anemone, and scallop and guanylate cyclase activation. J Biol Chem (1981) 1.23
The amino acid sequence of Clostridium pasteurianum ferredoxin. Biochem Biophys Res Commun (1964) 1.22
Increased activity of oleate-dependent type phospholipase D during actinomycin D-induced apoptosis in Jurkat T cells. J Immunol (1998) 1.22
Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor. Circ Res (1998) 1.22
Myofilaments in smooth muscle of guinea pigs taenia coli. J Cell Biol (1968) 1.21
Endoscopic management and follow up of Dieulafoy lesion in the upper gastrointestinal tract. Endoscopy (2005) 1.20
Essential role of myosin light chain kinase in the mechanism for MgATP-dependent priming of exocytosis in adrenal chromaffin cells. J Neurosci (1994) 1.20
Structure of human fetal and adult olfactory neuroepithelium. Arch Otolaryngol (1984) 1.19
Formation of hilar collaterals or cavernous transformation after portal vein obstruction by hepatocellular carcinoma. Observations in ten patients. Gastroenterology (1984) 1.18
Tetrahymena: a system for studying dynamic membrane alterations within the eukaryotic cell. Biochim Biophys Acta (1977) 1.18
Angiotensin II type 2 receptor is upregulated in human heart with interstitial fibrosis, and cardiac fibroblasts are the major cell type for its expression. Circ Res (1998) 1.17
Nonmuscle and smooth muscle myosin light chain mRNAs are generated from a single gene by the tissue-specific alternative RNA splicing. J Biol Chem (1987) 1.17
Molecular control of membrane properties during temperature acclimation. Membrane fluidity regulation of fatty acid desaturase action? Biochemistry (1976) 1.16
Functional B-cell response in intrahepatic lymphoid follicles in chronic hepatitis C. Hepatology (1999) 1.16
dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates. EMBO J (1995) 1.16
Performance evaluation of fuzzy classifier systems for multidimensional pattern classification problems. IEEE Trans Syst Man Cybern B Cybern (1999) 1.16
Effect of calcium removal on thermosensitivity of preoptic neurons in hypothalamic slices. Neurosci Lett (1980) 1.16
Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. Cell Death Differ (2000) 1.16
Clinicopathologic features of encapsulated hepatocellular carcinoma: a study of 26 cases. Cancer (1977) 1.15
Asplenia and polysplenia syndrome. Acta Pathol Jpn (1982) 1.14
Psychological effects of forest environments on healthy adults: Shinrin-yoku (forest-air bathing, walking) as a possible method of stress reduction. Public Health (2006) 1.14
Effects of antifungal agents on ergosterol biosynthesis in Candida albicans and Trichophyton mentagrophytes: differential inhibitory sites of naphthiomate and miconazole. J Invest Dermatol (1985) 1.14
An evaluation of methanolysis for thin-layer chromatographic analysis of the monosaccharides in an immunologically active polysaccharide-peptide complex. J Chromatogr (1969) 1.14
Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C. Biochem Biophys Res Commun (1988) 1.13
Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation. J Biol Chem (1998) 1.13
MDM2 enhances the function of estrogen receptor alpha in human breast cancer cells. Biochem Biophys Res Commun (2001) 1.13
Studies of membrane formation in Tetrahymena pyriformis. II. Isolation and lipid analysis of cell fractions. J Cell Biol (1971) 1.12
Fine structure of the human newborn and infant vocal fold mucosae. Ann Otol Rhinol Laryngol (2001) 1.11
The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood (1994) 1.11
Succinate dehydrogenase activities of fibers in the rat extensor digitorum longus, soleus, and cardiac muscles. Arch Histol Cytol (1999) 1.11
Quantitative analysis of contraction band and coagulation necrosis after ischemia and reperfusion in the porcine heart. Circulation (1987) 1.11
The ram: a novel low molecular weight GTP-binding protein cDNA from a rat megakaryocyte library. FEBS Lett (1990) 1.10
Alpha B-crystallin in skeletal muscle: purification and localization. J Biochem (1991) 1.10
Distribution of albumin- and/or alpha-fetoprotein-positive cells in hepatocellular carcinoma. Lab Invest (1981) 1.10
Detection of hepatocellular carcinoma during a clinical follow-up of chronic liver disease: observations in 31 patients. Gastroenterology (1978) 1.10
Liver pathology of idiopathic portal hypertension. Comparison with non-cirrhotic portal fibrosis of India. The Japan idiopathic portal hypertension study. Liver (1982) 1.09
Bradykinin-induced transient accumulation of inositol trisphosphate in neuron-like cell line NG108-15 cells. FEBS Lett (1985) 1.09
Unilateral associated laryngeal paralysis due to varicella-zoster virus: virus antibody testing and videofluoroscopic findings. J Laryngol Otol (2007) 1.09