Published in EMBO J on December 01, 1992
RNA editing in kinetoplastid protozoa. Microbiol Mol Biol Rev (1997) 2.58
Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activities. Proc Natl Acad Sci U S A (1996) 2.34
Identification of novel components of Trypanosoma brucei editosomes. RNA (2003) 2.30
Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complex. Mol Cell Biol (2001) 2.28
Complexes from Trypanosoma brucei that exhibit deletion editing and other editing-associated properties. Mol Cell Biol (1996) 2.27
Uridylate addition and RNA ligation contribute to the specificity of kinetoplastid insertion RNA editing. Mol Cell Biol (2000) 2.20
Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA (2001) 2.15
Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01
Kinetoplastid RNA-editing-associated protein 1 (REAP-1): a novel editing complex protein with repetitive domains. EMBO J (1998) 1.97
Four related proteins of the Trypanosoma brucei RNA editing complex. Mol Cell Biol (2001) 1.97
The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondria. Nucleic Acids Res (1997) 1.89
RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol (2007) 1.87
Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA (2006) 1.86
Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex business. RNA (2003) 1.85
Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs. Mol Cell Biol (1997) 1.82
Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21. EMBO J (2001) 1.73
Association of guide RNA binding protein gBP21 with active RNA editing complexes in Trypanosoma brucei. Mol Cell Biol (1998) 1.66
TbMP81 is required for RNA editing in Trypanosoma brucei. EMBO J (2002) 1.65
Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. EMBO J (2005) 1.61
Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editing. Eukaryot Cell (2002) 1.55
Assembly and function of the RNA editing complex in Trypanosoma brucei requires band III protein. Mol Cell Biol (2002) 1.53
Characterization of two classes of ribonucleoprotein complexes possibly involved in RNA editing from Leishmania tarentolae mitochondria. EMBO J (1994) 1.36
Trypanosoma brucei mitochondrial guide RNA-mRNA chimera-forming activity cofractionates with an editing-domain-specific endonuclease and RNA ligase and is mimicked by heterologous nuclease and RNA ligase. Mol Cell Biol (1995) 1.36
Assembly of mitochondrial ribonucleoprotein complexes involves specific guide RNA (gRNA)-binding proteins and gRNA domains but does not require preedited mRNA. Mol Cell Biol (1994) 1.35
Different Trypanosoma brucei guide RNA molecules associate with an identical complement of mitochondrial proteins in vitro. Nucleic Acids Res (1994) 1.34
Trypanosoma brucei U insertion and U deletion activities co-purify with an enzymatic editing complex but are differentially optimized. Nucleic Acids Res (1998) 1.34
Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Mol Cell Biol (2000) 1.31
A three-dimensional working model for a guide RNA from Trypanosoma brucei. Nucleic Acids Res (1997) 1.30
Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer. Wiley Interdiscip Rev RNA (2011) 1.29
Alternative editing of cytochrome c oxidase III mRNA in trypanosome mitochondria generates protein diversity. EMBO Rep (2006) 1.22
Composition of the editing complex of Trypanosoma brucei. Philos Trans R Soc Lond B Biol Sci (2002) 1.22
Cloning and characterization of two guide RNA-binding proteins from mitochondria of Crithidia fasciculata: gBP27, a novel protein, and gBP29, the orthologue of Trypanosoma brucei gBP21. Nucleic Acids Res (2001) 1.22
Editing domains of Trypanosoma brucei mitochondrial RNAs identified by secondary structure. Mol Cell Biol (1995) 1.21
Processing of polycistronic guide RNAs is associated with RNA editing complexes in Trypanosoma brucei. EMBO J (2000) 1.19
Trypanosoma brucei mitochondria contain RNA helicase activity. Nucleic Acids Res (1994) 1.17
Guide RNA-mRNA chimeras, which are potential RNA editing intermediates, are formed by endonuclease and RNA ligase in a trypanosome mitochondrial extract. Mol Cell Biol (1995) 1.16
RNA sequence and base pairing effects on insertion editing in Trypanosoma brucei. Mol Cell Biol (2002) 1.15
Trypanosoma brucei RNA editing complex: band II is structurally critical and maintains band V ligase, which is nonessential. Mol Cell Biol (2003) 1.10
Mechanism of the gBP21-mediated RNA/RNA annealing reaction: matchmaking and charge reduction. Nucleic Acids Res (2002) 1.09
Mitochondrial RNA editing in trypanosomes: small RNAs in control. Biochimie (2014) 1.07
Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo. EMBO J (2009) 1.04
Uridine insertion into preedited mRNA by a mitochondrial extract from Leishmania tarentolae: stereochemical evidence for the enzyme cascade model. Mol Cell Biol (1996) 1.03
In vitro RNA editing-like activity in a mitochondrial extract from Leishmania tarentolae. EMBO J (1995) 1.03
UTP-dependent and -independent pathways of mRNA turnover in Trypanosoma brucei mitochondria. Mol Cell Biol (2000) 1.01
Alternative RNA editing produces a novel protein involved in mitochondrial DNA maintenance in trypanosomes. Mol Cell Biol (2008) 1.01
In Trypanosoma brucei RNA editing, band II enables recognition specifically at each step of the U insertion cycle. Mol Cell Biol (2005) 0.99
Mitochondrial glutamate dehydrogenase from Leishmania tarentolae is a guide RNA-binding protein. Mol Cell Biol (1997) 0.99
Dyskinetoplastic Trypanosoma brucei contains functional editing complexes. Eukaryot Cell (2003) 0.99
Guide RNA requirement for editing-site-specific endonucleolytic cleavage of preedited mRNA by mitochondrial ribonucleoprotein particles in Trypanosoma brucei. Mol Cell Biol (1997) 0.98
RNA binding and core complexes constitute the U-insertion/deletion editosome. Mol Cell Biol (2014) 0.98
Interactions of mRNAs and gRNAs involved in trypanosome mitochondrial RNA editing: structure probing of an mRNA bound to its cognate gRNA. RNA (2001) 0.98
Quantitation of RNA editing substrates, products and potential intermediates: implications for developmental regulation. Nucleic Acids Res (1995) 0.97
The specificity of nucleotide removal during RNA editing in Trypanosoma brucei. RNA (2001) 0.96
In Trypanosoma brucei RNA editing, TbMP18 (band VII) is critical for editosome integrity and for both insertional and deletional cleavages. Mol Cell Biol (2006) 0.92
Sequence and structural requirements for optimal guide RNA-directed insertional editing within Leishmania tarentolae. RNA (2003) 0.90
RNA-editing-associated protein 1 null mutant reveals link to mitochondrial RNA stability. RNA (2007) 0.88
TbDSS-1, an essential Trypanosoma brucei exoribonuclease homolog that has pleiotropic effects on mitochondrial RNA metabolism. Eukaryot Cell (2004) 0.88
RNA editing in Trypanosoma brucei: characterization of gRNA U-tail interactions with partially edited mRNA substrates. Nucleic Acids Res (2001) 0.88
T. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle. RNA (2006) 0.85
U-Insertion/Deletion mRNA-Editing Holoenzyme: Definition in Sight. Trends Parasitol (2015) 0.84
Trypanosoma brucei ATPase subunit 6 mRNA bound to gA6-14 forms a conserved three-helical structure. RNA (2008) 0.84
The yeast protein encoded by PUB1 binds T-rich single stranded DNA. Nucleic Acids Res (1994) 0.83
Complete cycles of bloodstream trypanosome RNA editing in vitro. RNA (2004) 0.82
Two distinct roles for terminal uridylyl transferases in RNA editing. Proc Natl Acad Sci U S A (2003) 0.78
The impact of mRNA structure on guide RNA targeting in kinetoplastid RNA editing. PLoS One (2010) 0.78
Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences. Cell (1985) 7.49
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell (1990) 6.24
The "spliceosome": yeast pre-messenger RNA associates with a 40S complex in a splicing-dependent reaction. Science (1985) 5.82
Guide RNAs in kinetoplastid mitochondria have a nonencoded 3' oligo(U) tail involved in recognition of the preedited region. Cell (1990) 3.45
Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma brucei. Cell (1988) 3.26
New culture medium for maintenance of tsetse tissues and growth of trypanosomatids. J Protozool (1977) 2.91
RNA editing and the mitochondrial cryptogenes of kinetoplastid protozoa. Cell (1989) 2.74
RNA editing involves indiscriminate U changes throughout precisely defined editing domains. Cell (1990) 2.40
Ribonucleoprotein complex formation during pre-mRNA splicing in vitro. Mol Cell Biol (1986) 2.33
Organization of minicircle genes for guide RNAs in Trypanosoma brucei. Cell (1990) 2.28
Chimeric gRNA-mRNA molecules with oligo(U) tails covalently linked at sites of RNA editing suggest that U addition occurs by transesterification. Cell (1991) 2.23
RNA editing: world's smallest introns? Cell (1991) 2.17
Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae. J Protozool (1974) 2.00
Kinetoplast DNA minicircles encode guide RNAs for editing of cytochrome oxidase subunit III mRNA. Cell (1990) 1.99
The Leishmania kinetoplast-mitochondrion contains terminal uridylyltransferase and RNA ligase activities. J Biol Chem (1989) 1.97
The sequence of the gene for cytochrome c oxidase subunit I, a frameshift containing gene for cytochrome c oxidase subunit II and seven unassigned reading frames in Trypanosoma brucei mitochondrial maxi-circle DNA. Nucleic Acids Res (1984) 1.95
Further characterization of the extremely small mitochondrial ribosomal RNAs from trypanosomes: a detailed comparison of the 9S and 12S RNAs from Crithidia fasciculata and Trypanosoma brucei with rRNAs from other organisms. Nucleic Acids Res (1985) 1.81
Specific cleavage of pre-edited mRNAs in trypanosome mitochondrial extracts. Mol Cell Biol (1992) 1.63
Kinetoplastid RNA editing: in vitro formation of cytochrome b gRNA-mRNA chimeras from synthetic substrate RNAs. Cell (1992) 1.63
Trypanosoma equiperdum minicircles encode three distinct primary transcripts which exhibit guide RNA characteristics. Mol Cell Biol (1991) 1.57
RNA editing in trypanosomes: is there a message? Trends Genet (1990) 1.54
Characterization of cytochrome c oxidase III transcripts that are edited only in the 3' region. Cell (1988) 1.52
Sedimentation analysis of polyadenylation-specific complexes. Mol Cell Biol (1988) 1.46
Intra-RNA and RNA-protein cross-linking techniques in Escherichia coli ribosomes. Methods Enzymol (1988) 1.31
Differential expression of mitochondrial genes between life cycle stages of Trypanosoma brucei. Proc Natl Acad Sci U S A (1985) 1.25
Diverse patterns of expression of the cytochrome c oxidase subunit I gene and unassigned reading frames 4 and 5 during the life cycle of Trypanosoma brucei. Mol Cell Biol (1985) 1.22
Transcription of kinetoplast DNA minicircles. Cell (1987) 1.17
RNA editing in kinetoplastid mitochondria. J Biol Chem (1990) 1.08
Transcripts from the frameshifted MURF3 gene from Crithidia fasciculata are edited by U insertion at multiple sites. EMBO J (1988) 1.07
The molecular biology of trypanosomes. Annu Rev Biochem (1982) 2.81
Addition of uridines to edited RNAs in trypanosome mitochondria occurs independently of transcription. J Biol Chem (1990) 2.76
Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and beta-thromboglobulin. Biochemistry (1986) 2.61
A block to human immunodeficiency virus type 1 assembly in murine cells. J Virol (2000) 2.47
RNA ligase and its involvement in guide RNA/mRNA chimera formation. Evidence for a cleavage-ligation mechanism of Trypanosoma brucei mRNA editing. J Biol Chem (1995) 2.46
Organization of minicircle genes for guide RNAs in Trypanosoma brucei. Cell (1990) 2.28
The mitochondrial tRNAs of Trypanosoma brucei are nuclear encoded. J Biol Chem (1990) 2.25
Killing of trypanosomes by the human haptoglobin-related protein. Science (1995) 2.18
Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA (2001) 2.15
Kinetoplastid RNA-editing-associated protein 1 (REAP-1): a novel editing complex protein with repetitive domains. EMBO J (1998) 1.97
Bacteriological survey of raw beef patties produced at establishments under federal inspection. Appl Microbiol (1975) 1.92
Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy. Hum Gene Ther (1999) 1.70
Kinetoplastid RNA editing: in vitro formation of cytochrome b gRNA-mRNA chimeras from synthetic substrate RNAs. Cell (1992) 1.63
Trypanosoma equiperdum minicircles encode three distinct primary transcripts which exhibit guide RNA characteristics. Mol Cell Biol (1991) 1.57
Comparative photocross-linking analysis of the tertiary structures of Escherichia coli and Bacillus subtilis RNase P RNAs. EMBO J (1998) 1.57
Developmental regulation of mitochondrial biogenesis in Trypanosoma brucei. J Bioenerg Biomembr (1994) 1.54
RNA editing in kinetoplastid mitochondria. FASEB J (1993) 1.48
Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes. J Cell Biol (1994) 1.46
Evaluation of virulence test procedures for Yersinia enterocolitica recovered from foods. J Appl Bacteriol (1981) 1.39
Modification of Trypanosoma brucei mitochondrial rRNA by posttranscriptional 3' polyuridine tail formation. Mol Cell Biol (1991) 1.36
Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Mol Cell Biol (2000) 1.31
Replication of kinetoplast DNA maxicircles. Cell (1984) 1.30
Developmental regulation of trypanosome mitochondrial gene expression. J Biol Chem (1987) 1.29
Two modified selenite media for the recovery of Yersinia enterocolitica from meats. Appl Environ Microbiol (1980) 1.27
Haptoglobin-related protein mediates trypanosome lytic factor binding to trypanosomes. J Biol Chem (2001) 1.27
Rational design of self-cleaving pre-tRNA-ribonuclease P RNA conjugates. Biochemistry (1994) 1.26
Identification of nuclear encoded precursor tRNAs within the mitochondrion of Trypanosoma brucei. J Biol Chem (1992) 1.25
RNA editing-associated protein 1 is an RNA binding protein with specificity for preedited mRNA. Mol Cell (2001) 1.22
Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme. RNA (2000) 1.22
Editing domains of Trypanosoma brucei mitochondrial RNAs identified by secondary structure. Mol Cell Biol (1995) 1.21
In vitro import of a nuclearly encoded tRNA into the mitochondrion of Trypanosoma brucei. Mol Cell Biol (1999) 1.21
Processing of polycistronic guide RNAs is associated with RNA editing complexes in Trypanosoma brucei. EMBO J (2000) 1.19
Transcription of kinetoplast DNA minicircles. Cell (1987) 1.17
Presence of a bent helix in fragments of kinetoplast DNA minicircles from several trypanosomatid species. Mol Biochem Parasitol (1984) 1.15
Biological characterization of Rev variation in equine infectious anemia virus. J Virol (1998) 1.14
The kinetoplast DNA of Trypanosoma equiperdum. Biochim Biophys Acta (1980) 1.10
Identification of individual nucleotides in the bacterial ribonuclease P ribozyme adjacent to the pre-tRNA cleavage site by short-range photo-cross-linking. Biochemistry (1998) 1.06
Posttranscriptional regulation of cytochrome c expression during the developmental cycle of Trypanosoma brucei. Mol Cell Biol (1988) 1.04
Trypanosoma brucei mitochondrial ribosomal RNA synthesis, processing and developmentally regulated expression. Mol Biochem Parasitol (1992) 1.04
Developmental regulation of Trypanosoma brucei cytochrome c reductase during bloodstream to procyclic differentiation. Mol Biochem Parasitol (1994) 1.04
A nuclear encoded and mitochondrial imported dicistronic tRNA precursor in Trypanosoma brucei. J Biol Chem (1999) 1.03
Identification of adenosine functional groups involved in substrate binding by the ribonuclease P ribozyme. Biochemistry (1999) 1.02
Organized packaging of kinetoplast DNA networks. Cell (1986) 1.02
Demonstration of kinetoplast DNA in dyskinetoplastic strains of Trypanosoma equiperdum. Science (1976) 1.00
The trypanosomatid Rieske iron-sulfur proteins have a cleaved presequence that may direct mitochondrial import. Biochim Biophys Acta (1995) 0.99
In vitro import of the Rieske iron-sulfur protein by trypanosome mitochondria. J Biol Chem (1996) 0.99
Biochemical methods for analysis of kinetoplastid RNA editing. Methods (1998) 0.99
Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide. Ann N Y Acad Sci (1996) 0.98
Guide RNA requirement for editing-site-specific endonucleolytic cleavage of preedited mRNA by mitochondrial ribonucleoprotein particles in Trypanosoma brucei. Mol Cell Biol (1997) 0.98
The lysosomal targeting and intracellular metabolism of trypanosome lytic factor by Trypanosoma brucei brucei. Mol Biochem Parasitol (2001) 0.97
Kinetoplast DNA of Bodo caudatus: a noncatenated structure. Mol Cell Biol (1986) 0.96
A single amino acid substitution in the group 1 Trypanosoma brucei gambiense haptoglobin-hemoglobin receptor abolishes TLF-1 binding. PLoS Pathog (2013) 0.95
The track of the pre-tRNA 5' leader in the ribonuclease P ribozyme-substrate complex. Biochemistry (1999) 0.93
Identification of haptoglobin as a natural inhibitor of trypanocidal activity in human serum. Proc Natl Acad Sci U S A (1995) 0.92
Insight into the mechanism of trypanosome lytic factor-1 killing of Trypanosoma brucei brucei. Mol Biochem Parasitol (2001) 0.92
Mechanisms and origins of RNA editing. Curr Opin Genet Dev (1994) 0.91
Cytochrome c reductase purified from Crithidia fasciculata contains an atypical cytochrome c1. J Biol Chem (1992) 0.91
Mechanism of resistance of African trypanosomes to cytotoxic human HDL. Nature (1997) 0.89
Detection of multiple variable antigen types in metacyclic populations of Trypanosoma brucei. Trans R Soc Trop Med Hyg (1979) 0.89
Cytochromes c1 of kinetoplastid protozoa lack mitochondrial targeting presequences. Biochim Biophys Acta (1993) 0.88
Bacteriological survey of frozen meat and gravy produced at establishments under federal inspection. Appl Microbiol (1973) 0.87
Import of a constitutively expressed protein into mitochondria from procyclic and bloodstream forms of Trypanosoma brucei. Mol Biochem Parasitol (2000) 0.87
Spontaneous epidural spinal hemorrhage. Am J Roentgenol Radium Ther Nucl Med (1969) 0.85
Concentration of testosterone in testis fluid of the rat. Endocrinology (1974) 0.83
Protein stability regulates the expression of cytochrome c during the developmental cycle of Trypanosoma brucei. Mol Biochem Parasitol (1993) 0.83
Expression and localization of serum resistance associated protein in Trypanosoma brucei rhodesiense. Mol Biochem Parasitol (1999) 0.83
Two-stage tuberculin testing with control antigens in patients residing in two chronic disease hospitals. J Am Geriatr Soc (1987) 0.83
Absence of detectable alteration in the kinetoplast DNA of a Trypanosoma brucei clone following loss of ability to infect the insect vector (Glossina morsitans). Mol Biochem Parasitol (1981) 0.81
Androgen levels in the rete testis fluid during sexual development. Experientia (1981) 0.81
Antigenic variation during the developmental cycle of Trypanosoma brucei. J Protozool (1984) 0.81
Molecular modeling to predict the structural and biological effects of mutations in a highly conserved histone mRNA loop sequence. J Biomol Struct Dyn (1992) 0.80
Reconstitution of the trypanolytic factor from components of a subspecies of human high-density lipoproteins. Mol Biochem Parasitol (1995) 0.80
Long-term results in the treatment of hydrocephalus. Neurosurg Clin N Am (1993) 0.79
Effects of hydroxyurea on Crithidia fasciculata. J Protozool (1979) 0.79
Kinetoplast DNA from normal and dyskinetoplastic strains of Trypanosoma equiperdum. Biochim Biophys Acta (1979) 0.79
Light and electron microscopical observations of the effects of high-density lipoprotein on growth of Plasmodium falciparum in vitro. Parasitology (2004) 0.78
Sequence of Trypanosoma brucei tRNA genes encoding cytosolic tRNAs. Nucleic Acids Res (1992) 0.78
Dyskinetoplasty in two species of trypanosomatids. J Cell Sci (1979) 0.78
Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase. J Neurochem (1995) 0.78
Developmentally regulated sensitivity of Trypanosoma brucei brucei to the cytotoxic effects of human high-density lipoprotein. Exp Parasitol (1995) 0.77
Relapse of monomorphic and pleomorphic Trypanosoma brucei infections in the mouse after chemotherapy. Z Parasitenkd (1982) 0.77
Rapid detection of staphylococcal thermonuclease on casings of naturally contaminated fermented sausages. Appl Environ Microbiol (1980) 0.77
Activity of human trypanosome lytic factor in mice. Mol Biochem Parasitol (2001) 0.77
Dream content and its relation to self-reported interpersonal behavior. Psychiatry (1977) 0.75
Notes on the endocrine system. J Am Assoc Nurse Anesth (1969) 0.75
Intussusception in the cat. Vet Rec (1968) 0.75
Squamous cell carcinoma of the parotid gland. Minn Med (1965) 0.75
Regulation of testosterone and dihydrotestosterone levels in rete testis fluid. Evidence for androgen biosynthesis in seminiferous tubules in vivo. Curr Top Mol Endocrinol (1975) 0.75
Cholestatic jaundice during imipramine therapy. JAMA (1968) 0.75
Another look at personal validation. J Pers Assess (1979) 0.75
Otitis externa associated with Pseudomonas aeruginosa infection. Vet Rec (1978) 0.75
Notes on the excretory system. J Am Assoc Nurse Anesth (1969) 0.75
Vascular trauma. J Lancet (1966) 0.75
Effects of testosterone and dihydrotestosterone on spermatogenesis, rete testis fluid, and peripheral androgen levels in hypophysectomized rats. Fertil Steril (1977) 0.75
Maintenance of rate testis fluid testosterone and dihydrotestosterone levels by pregnenolone and other C21 steroids in hypophysectomized rats. Endocrinology (1975) 0.75