Published in Science on July 26, 1957
The precipitin reaction between DNA and a serum factor in systemic lupus erythematosus. J Exp Med (1959) 5.26
Defective B cell tolerance checkpoints in systemic lupus erythematosus. J Exp Med (2005) 4.16
Anti-nuclear factors and serum complement in systemic lupus erythematosus. Bull N Y Acad Med (1962) 2.69
The reaction of the lupus erythematosus (L.E.) cell factor with deoxyribonucleoprotein of the cell nucleus. J Clin Invest (1959) 2.56
A clinical study of serum antinuclear factor. Br Med J (1961) 2.49
Release of DNA in circulating blood and induction of anti-DNA antibodies after injection of bacterial lipopolysaccharides. J Exp Med (1974) 2.34
Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J Clin Invest (1998) 2.27
SLOWLY SEDIMENTING MERCAPTOETHANOL-RESISTANT ANTINUCLEAR FACTORS RELATED ANTIGENICALLY TO M IMMUNOGLOBULINS (GAMMA-1M-GLOBULIN) IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS. J Clin Invest (1965) 2.19
The relation of immunoglobulin class, pattern of anti-nuclear antibody, and complement-fixing antibodies to DNA in sera from patients with systemic lupus erythematosus. J Clin Invest (1967) 1.82
A soluble acidic protein of the cell nucleus which reacts with serum from patients with systemic lupus erythermatosus and Sjögren's syndrome. J Clin Invest (1977) 1.82
Fluorescent antiglobulin studies in leukopenic and related disorders. J Clin Invest (1959) 1.71
Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis. J Exp Med (2004) 1.70
Complement and systemic lupus erythematosus. Arthritis Res (2002) 1.58
Serum factors in lupus erythematosus and other diseases reacting with cell nuclei and nucleoprotein extracts: electrophoretic. ultracentrifugal and chromatographic studies. J Clin Invest (1960) 1.53
Identification of DNA-binding lymphocytes in patients with systemic lupus erythematosus. J Clin Invest (1975) 1.38
ANTI-DNA ANTIBODIES IN HYPERIMMUNIZED RABBITS. J Exp Med (1965) 1.27
Serum anti-nuclear factor. Laboratory studies. Ann Rheum Dis (1962) 1.12
Studies on the mechanism of the lupus erythematosus (L.E.) phenomenon. J Clin Invest (1959) 1.08
Autoantigens in systemic autoimmunity: critical partner in pathogenesis. J Intern Med (2009) 1.07
Reaction of lupus erythematosus serum with nuclei of circulating and non-circulating cells. Br Med J (1958) 1.06
Comparison of a semiautomated fluorescent immunoassay system and indirect immunofluorescence for detection of antinuclear antibodies in human serum. J Clin Microbiol (1979) 1.04
Nuclear fluorescence employing antinucleoside immunoglobulins. J Exp Med (1967) 1.00
Neutrophil extracellular chromatin traps connect innate immune response to autoimmunity. Semin Immunopathol (2013) 0.99
Associations between antinuclear antibody staining patterns and clinical features of systemic lupus erythematosus: analysis of a regional Swedish register. BMJ Open (2013) 0.98
ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus. J Immunol (2009) 0.98
Relationship between deoxyribonucleoprotein and deoxyribonucleic acid antibodies in systemic lupus erythematosus. J Clin Invest (1973) 0.95
B cells as a therapeutic target in autoimmune disease. Arthritis Res Ther (2003) 0.90
COMPARATIVE STUDY FOR THE DETECTION OF ANTINUCLEAR FACTORS WITH THE FLUORESCENT ANTIBODY TECHNIQUE. Ann Rheum Dis (1964) 0.88
Fluorescent antibody procedure for lupus erythematosus: comparative use of nucleated erythrocytes and calf thymus cells. Am J Public Health Nations Health (1961) 0.87
The incidence of antibodies to a soluble nuclear antigen in the sera of patients with systemic lupus erythematosus and rheumatoid arthritis estimated with the mixed haemadsorption technique. Clin Exp Immunol (1967) 0.87
Anti-deoxyribonucleic acid antibody associated with persistent infection of mink with Aleutian disease virus. Infect Immun (1980) 0.86
Anti-dsDNA Antibodies are one of the many autoantibodies in systemic lupus erythematosus. F1000Res (2015) 0.85
Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers. J Exp Med (1985) 0.82
IMMUNOFLUORESCENT STUDIES ON THE OCCURRENCE OF ANTINUCLEAR FACTOR IN NORMAL HUMAN SERUM. Am J Pathol (1964) 0.82
Protein microarrays: a new tool for the study of autoantibodies in immunodeficiency. Front Immunol (2015) 0.80
Antinuclear factor in rheumatoid arthritis and related diseases. Ann Rheum Dis (1967) 0.80
In vitro effect of antibodies to DNA on the template activity of DNA. J Clin Invest (1968) 0.77
Pathogenesis of proliferative lupus nephritis from a historical and personal perspective. Clin Immunol (2016) 0.76
Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus. Eur J Immunol (2015) 0.76
Inhibition of antinuclear factor reaction by chloroquine. Immunology (1965) 0.75
Establishing a reference interval for serum anti-dsDNA antibody: A large Chinese Han population-based multi-center study. PLoS One (2017) 0.75
Targeted therapies in rheumatoid arthritis: Focus on rituximab. Biologics (2007) 0.75
Anti-DNP antibody responses to DNP-histone H1 in mice. Immunology (1979) 0.75
Comparison between the latex nucleoprotein test and the fluorescent method for the demonstration of antinuclear factor. Ann Rheum Dis (1962) 0.75
Antinucleic acid antibodies. J Clin Pathol Suppl (R Coll Pathol) (1979) 0.75
Pathology and Pathogenesis of the Diffuse Collagen Diseases : Part III. Can Med Assoc J (1960) 0.75
Spotlight on blisibimod and its potential in the treatment of systemic lupus erythematosus: evidence to date. Drug Des Devel Ther (2017) 0.75
Autoimmune disorders: a concept of treatment based on mechanisms of disease. Springer Semin Immunopathol (2003) 0.75
Zone electrophoresis in a starch supporting medium. Proc Soc Exp Biol Med (1952) 13.49
Electrophoresis of proteins on filter paper. J Gen Physiol (1951) 13.06
Zone electrophoresis. Methods Biochem Anal (1954) 10.49
Interaction of the rheumatoid factor with antigen-antibody complexes and aggregated gamma globulin. J Exp Med (1958) 7.85
Primary biliary cirrhosis. Medicine (Baltimore) (1950) 7.07
The carbohydrate of gamma-globulin and myeloma proteins. J Exp Med (1956) 5.85
An unusual protein component of high molecular weight in the serum of certain patients with rheumatoid arthritis. J Exp Med (1957) 5.79
H CHAIN SUBGROUPS OF MYELOMA PROTEINS AND NORMAL 7S GAMMA-GLOBULIN. J Exp Med (1964) 5.64
Gamma globulin complexes in rheumatoid arthritis and certain other conditions. J Clin Invest (1961) 5.62
Isolation of a thermolabile serum protein which precipitates gamma-globulin aggregates and participates in immune hemolysis. Proc Soc Exp Biol Med (1961) 5.41
Complement fixation with cell nuclei and DNA in lupus erythematosus. Proc Soc Exp Biol Med (1957) 5.31
The precipitin reaction between DNA and a serum factor in systemic lupus erythematosus. J Exp Med (1959) 5.26
Immunological relationships among the myeloma proteins. J Exp Med (1955) 5.11
Role of gamma globulins in pathogenesis of renal lesions in systemic lupus erythematosus and chronic membranous glomerulonephritis, with an observation on the lupus erythematosus cell reaction. J Exp Med (1957) 5.03
Lipoprotein patterns of serum obtained by zone electrophoresis. J Clin Invest (1952) 4.97
The localization of in vivo bound complement in tissue section. J Exp Med (1962) 4.46
Anti-gamma-globulin factors in human sera revealed by enzymatic splitting of anti-Rh antibodies. Vox Sang (1963) 4.32
Immunological studies of human gamma-globulin. Relation of the precipitin lines of whole gamma-globulin to those of the fragments produced by papain. J Exp Med (1960) 4.31
New hemoglobin in normal adult blood. Science (1955) 4.23
Rheumatoid factor, complement, and conglutinin aberrations in patients with subacute bacterial endocarditis. J Clin Invest (1962) 3.96
Immunologic differences between the 19 S and 7 S components of normal human gamma-globulin. J Immunol (1957) 3.89
Physical properties of the red cell agglutinins in acquired hemolytic anemia. J Exp Med (1957) 3.79
Anti-cytoplasmic factors in the sera of patients with systemic lupus erythematosus and certain other diseases. Arthritis Rheum (1960) 3.66
Two types of gamma-globulin differing in carbohydrate content. Proc Soc Exp Biol Med (1956) 3.49
Genetic characters of human gamma-globulins in myeloma proteins. J Exp Med (1962) 3.26
The relationship between serum lipids and skin xanthomata in 18 patients with primary biliary cirrhosis. J Clin Invest (1949) 3.03
Ultracentrifugal studies of major non-lipide electrophoretic components of normal human serum. J Biol Chem (1957) 2.89
INDIVIDUAL ANTIGENIC SPECIFICITY OF MYELOMA PROTEINS. CHARACTERISTICS AND LOCALIZATION TO SUBUNITS. J Exp Med (1965) 2.87
Observations on the minor basic hemoglobin component in the blood of normal individuals and patients with thalassemia. J Clin Invest (1957) 2.84
Observations concerning positive serologic reactions for rheumatoid factor in certain patients with sarcoidosis and other hyperglobulinemic states. Arthritis Rheum (1958) 2.78
Relation between certain myeloma proteins and normal gamma globulin. Proc Soc Exp Biol Med (1951) 2.74
BETA-2A AGLOBULINEMIA IN TWO HEALTHY MEN. J Lab Clin Med (1964) 2.72
Filter paper electrophoresis with special reference to urinary proteins. J Lab Clin Med (1953) 2.70
Anti-nuclear factors and serum complement in systemic lupus erythematosus. Bull N Y Acad Med (1962) 2.69
Localization of two genetic factors to different areas of gamma-globulin molecules. Science (1962) 2.68
The problem of chronic liver disease in young women. Am J Med (1956) 2.56
Plasma proteins and the gastrointestinal tract. N Engl J Med (1962) 2.51
Antibodies to rabbit gamma-globulin after immunizing with various preparations of autologous gamma-globulin. Proc Soc Exp Biol Med (1963) 2.44
Unusual sedimentation and sulfhydryl sensitivity of certain isohemagglutinins and skin-sensitizing antibody. Proc Soc Exp Biol Med (1962) 2.44
Specificity of the reaction between rheumatoid factors and gamma globulin. J Exp Med (1961) 2.43
Studies on the isolation and characterization of the "rheumatoid factor". J Clin Invest (1959) 2.38
The occurrence of rheumatoid factor and other abnormalities in families of patients with agammaglobulinemia. Arthritis Rheum (1962) 2.31
ACTIVITY OF DISSOCIATED AND REASSOCIATED 19S ANTI-GAMMA-GLOBULINS. J Exp Med (1964) 2.29
AUTOANTIBODIES AND DISEASE. Adv Immunol (1964) 2.29
Abnormalities of copper metabolism in Wilson's disease and their relationship to the aminoaciduria. J Clin Invest (1954) 2.27
Relation of high molecular weight proteins to the serological reactions in rheumatoid arthritis. Ann Rheum Dis (1957) 2.13
The L. E. cell and the L. E. serum factors. Bull N Y Acad Med (1959) 2.12
A RELATIONSHIP BETWEEN THE H CHAIN GROUPS OF 7S GAMMA-GLOBULIN AND THE GM SYSTEM. Nature (1964) 2.12
Comparative levels of high molecular weight (19S) gamma globulin in maternal and umbilical cord sera. J Lab Clin Med (1958) 2.12
SEPARATION OF RHEUMATOID FACTORS OF DIFFERENT SPECIFICITIES USING COLUMNS CONJUGATED WITH GAMMA-GLOBULIN. Arthritis Rheum (1963) 2.07
Electrolyte studies on patients with cirrhosis of the liver. J Clin Invest (1950) 1.94
LOCALIZATION OF ANTIBODIES IN GROUP I AND GROUP II GAMMA-GLOBULINS. J Exp Med (1963) 1.92
Electrophoretic studies of oxytocin and vasopressin. J Biol Chem (1953) 1.91
High molecular weight antibodies. Ann N Y Acad Sci (1960) 1.88
STUDIES ON HUMAN ANTIBODIES. II. DISTRIBUTION OF GENETIC FACTORS. J Exp Med (1964) 1.79
Studies of a Waldenstrom-type macroglobulin with rheumatoid factor properties. J Lab Clin Med (1961) 1.78
Correlation of antinuclear antibodies and nuclear staining patterns. Lancet (1961) 1.67
Clinical studies of seven patients with rheumatoid arthritis and uniquely large amounts of rheumatoid factor. Arthritis Rheum (1958) 1.61
The stabilization of serum lipid emulsions by serum phospholipids. J Exp Med (1949) 1.61
Localization of Cu64 in serum fractions following oral administration: an alteration in Wilson's disease. Proc Soc Exp Biol Med (1954) 1.59
Anuphylactic reactions in the skin of the guinea pig with high and low molecular weight antibodies and gamma globulins. J Exp Med (1960) 1.52
The relationship between serum lipids and the electrophoretic pattern, with particular reference to patients with primary biliary cirrhosis. J Clin Invest (1949) 1.50
Antibodies to genetic types of gamma globulin after multiple transfusions. Science (1963) 1.48
The alpha2 lipoproteins of human serum; correlation of ultracentrifugal and electrophoretic properties. J Clin Invest (1956) 1.46
Ultracentrifugal characteristics and carbohydrate content of macromolecular gamma-globulins. Clin Chim Acta (1959) 1.42
ISOLATION OF 7S AND 19S GAMMA GLOBULINS. Methods Med Res (1964) 1.38
Minor hemoglobin components of normal human blood. Fed Proc (1957) 1.38
Metabolic studies in Wilson's disease using Cu64. J Lab Clin Med (1955) 1.28
Isozymes of lactice dehydrogenase; their alterations in arthritic synovial fluid and sera. J Clin Invest (1962) 1.24
Increased portal pressure and ascites in rats following ligation of portal vein. Proc Soc Exp Biol Med (1949) 1.24
Phospholipid studies of different serum lipoproteins employing P32. Proc Soc Exp Biol Med (1955) 1.13
Passive cutaneous anaphylaxis reactions with a systemic lupus erythematosus serum factor and isolated DNA. J Immunol (1960) 1.12
Observation on the amino acid composition of human hemoglobins. Biochim Biophys Acta (1957) 1.11
Significance of the rheumatoid factor. Arthritis Rheum (1958) 1.05
Systemic lupus erythematosus--disease of an unusual immunologic responsiveness? Am J Med (1959) 1.01
Portal blood in collateral veins of patients with cirrhosis; acetylation by the intestine. Proc Soc Exp Biol Med (1950) 1.01
RHEUMATOID ARTHRITIS. Annu Rev Med (1964) 1.00
GENETIC CHARACTERS AND THE POLYPEPTIDE CHAINS OF VARIOUS TYPES OF GAMMA-GLOBULIN. Cold Spring Harb Symp Quant Biol (1964) 0.99
Studies of the rabbit antibodies which sensitize red blood cells for agglutination by rheumatoid factors. Arthritis Rheum (1961) 0.97
The L.E. cell phenomenon. Annu Rev Med (1960) 0.94
Osmotic pressure measurements of serum and ascitic fluid in patients with cirrhosis of the liver. J Clin Invest (1954) 0.85
IMMUNOLOGICAL ASPECTS OF CONNECTIVE TISSUE DISORDERS. Fed Proc (1964) 0.81
GENETIC STUDIES OF SYSTEMIC LUPUS ERYTHEMATOSUS. Arthritis Rheum (1963) 0.79
MYELOMA PROTEINS AND ANTIBODIES. Am J Med (1965) 0.78
THE STRUCTURE OF RHEUMATOID FACTORS. Arthritis Rheum (1963) 0.77
Infectious hepatitis; clinical aspects. Bull N Y Acad Med (1948) 0.75
Arteriosclerosis and serum lipids in diabetes mellitus. Angiology (1950) 0.75
Value and limitations of the thymol turbidity test as an index of liver disease. Am J Med (1948) 0.75
Estimation of alterations of serum gamma globulin by a turbidimetric technique. Proc Soc Exp Biol Med (1947) 0.75
Application of turbidimetric methods for estimation of gamma globulin and total lipid to the study of patients with liver disease. Gastroenterology (1948) 0.75
Turbidimetric studies of serum lipids in liver disease. Trans Conf Liver Inj (1948) 0.75
The use of concentrated human serum albumin in the treatment of cirrhosis of the liver. J Clin Invest (1948) 0.75
Chronic liver disease following infectious hepatitis; abnormal convalescence from initial attack. Ann Intern Med (1947) 0.75