Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

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Published in J Exp Med on February 01, 1992

Authors

H Groux1, G Torpier, D Monté, Y Mouton, A Capron, J C Ameisen

Author Affiliations

1: Unité Institut National de la Santé et de la Recherche Médicale U167-Centre National de la Recherche Scientifique 624, Instiut Pastéur, Lille, France.

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Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. EMBO J (1993) 1.86

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The apoptosis-1/Fas protein in human systemic lupus erythematosus. J Clin Invest (1994) 1.37

In vivo analysis of Fas/FasL interactions in HIV-infected patients. J Clin Invest (1998) 1.36

Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to disease. J Clin Invest (1994) 1.36

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Apoptotic regulation of T cells and absence of immune deficiency in virus-infected gamma interferon receptor knockout mice. J Virol (1998) 1.32

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Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes. J Virol (1998) 1.29

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Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism. J Virol (2003) 1.25

Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia. J Clin Invest (1996) 1.25

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CD28: a signalling perspective. Biochem J (1996) 1.08

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Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. Proc Natl Acad Sci U S A (1994) 1.07

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Enhanced expression of CTLA-4 (CD152) on CD4+ T cells in HIV infection. Clin Exp Immunol (1999) 1.04

T-cell activation influences initial DNA synthesis of simian immunodeficiency virus in resting T lymphocytes from macaques. J Virol (1993) 1.03

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Role of the Fas/FasL pathway in HIV or SIV disease. Retrovirology (2009) 1.02

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Cell death: the significance of apoptosis. Int Rev Cytol (1980) 24.88

The staphylococcal enterotoxins and their relatives. Science (1990) 11.99

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Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc Natl Acad Sci U S A (1990) 4.80

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The role of the T cell receptor in positive and negative selection of developing T cells. Science (1990) 3.64

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A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature (1991) 3.47

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance. J Exp Med (1990) 3.45

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature (1989) 3.23

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AIDS pathogenesis: a dynamic interaction between HIV and the immune system. Immunol Today (1990) 1.60

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[Immunoenzymologic diagnosis of parasitic diseases. II. Quantitative immunoenzymology]. Lille Med (1976) 2.74

PML induces a novel caspase-independent death process. Nat Genet (1998) 2.66

Immunity after treatment of human schistosomiasis: association between IgE antibodies to adult worm antigens and resistance to reinfection. Eur J Immunol (1992) 2.33

YOPRO-1 permits cytofluorometric analysis of programmed cell death (apoptosis) without interfering with cell viability. J Immunol Methods (1995) 2.25

Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc Natl Acad Sci U S A (1994) 2.21

Specific IgE antibodies in immune adherence of normal macrophages to Schistosoma mansoni schistosomules. Nature (1975) 2.19

Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia. Int Arch Allergy Appl Immunol (1983) 2.17

A new function for platelets: IgE-dependent killing of schistosomes. Nature (1983) 2.11

Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med (1986) 2.03

Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med (1994) 2.01

In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms. Antimicrob Agents Chemother (1996) 1.96

High-affinity IgE receptor on eosinophils is involved in defence against parasites. Nature (1994) 1.95

Ligand binding was acquired during evolution of nuclear receptors. Proc Natl Acad Sci U S A (1997) 1.94

On the evolution of programmed cell death: apoptosis of the unicellular eukaryote Leishmania major involves cysteine proteinase activation and mitochondrion permeabilization. Cell Death Differ (2002) 1.90

Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease. J Exp Med (1992) 1.88

Role of IgE receptors in effector function of human eosinophils. J Immunol (1984) 1.87

T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons. J Exp Med (1995) 1.80

Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection. J Exp Med (2001) 1.79

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc Natl Acad Sci U S A (2001) 1.74

Molecular crosstalk in host-parasite relationships: schistosome- and leech-host interactions. Parasitol Today (2000) 1.73

Molecular characterization of a 23-kilodalton major antigen secreted by Toxoplasma gondii. Proc Natl Acad Sci U S A (1989) 1.73

Adenovirus type 2 assembly analyzed by reversible cross-linking of labile intermediates. J Virol (1978) 1.72

IgA antibodies against P30 as markers of congenital and acute toxoplasmosis. Lancet (1988) 1.70

Programmed cell death in mature erythrocytes: a model for investigating death effector pathways operating in the absence of mitochondria. Cell Death Differ (2001) 1.69

Serodiagnosis of toxoplasma infection using a purified parasite protein (P30). Clin Exp Immunol (1985) 1.64

A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier. J Cell Biol (1997) 1.64

The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response. EMBO Rep (2001) 1.64

Fc receptors for IgE on human and rat eosinophils. J Immunol (1981) 1.63

Cellular and molecular mechanisms of senescent erythrocyte phagocytosis by macrophages. A review. Biochimie (1998) 1.62

Evidence for IgE-dependent cytotoxicity by rat eosinophils. J Immunol (1981) 1.61

The glutathione transferase activity and tissue distribution of a cloned Mr28K protective antigen of Schistosoma mansoni. EMBO J (1988) 1.55

ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells. Br J Cancer (2003) 1.53

Schistosoma mansoni schistosomula reduce E-selectin and VCAM-1 expression in TNF-alpha-stimulated lung microvascular endothelial cells by interfering with the NF-kappaB pathway. Eur J Immunol (1999) 1.49

Molecular cloning of a protective antigen of schistosomes. Nature (1987) 1.49

Interaction between IgE complexes and macrophages in the rat: a new mechanism of macrophage activation. Eur J Immunol (1977) 1.48

Analysis of the Mycobacterium tuberculosis 85A antigen promoter region. J Bacteriol (1995) 1.48

Quantitative determination of specific IgE antibodies to Echinococcus granulosus and IgE levels in sera from patients with hydatid disease. Immunology (1975) 1.47

Increased secretion of tumor necrosis factor alpha and interleukin-6 by alveolar macrophages consecutive to the development of the late asthmatic reaction. J Allergy Clin Immunol (1991) 1.46

[Antigenic structure of helminthes. Immunological aspects of the host-parasite relationship]. Pathol Biol (1968) 1.45

Involvement of immunoglobulin E in the secretory processes of alveolar macrophages from asthmatic patients. J Clin Invest (1983) 1.44

Enzyme release and superoxide anion production by human alveolar macrophages stimulated with immunoglobulin E. Clin Exp Immunol (1980) 1.42

Receptor for IgG(Fc) and human beta2-microglobulin on S. mansoni schistosomula. Nature (1979) 1.41

Schistosomiasis co-infection in humans influences inflammatory markers in uncomplicated Plasmodium falciparum malaria. Parasite Immunol (2005) 1.40

A purified 28,000 dalton protein from Schistosoma mansoni adult worms protects rats and mice against experimental schistosomiasis. J Immunol (1987) 1.39

Functional role of human IgG subclasses in eosinophil-mediated killing of schistosomula of Schistosoma mansoni. J Immunol (1989) 1.39

Fibronectin receptors on Trypanosoma cruzi trypomastigotes and their biological function. Nature (1984) 1.38

[Hantavirus infection without renal involvement]. Rev Med Interne (1994) 1.38

Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina. Dev Dyn (2003) 1.38

[Eosinophils and pathology of the digestive tract]. Gastroenterol Clin Biol (1990) 1.38

CD3-mediated apoptosis of human medullary thymocytes and activated peripheral T cells: respective roles of interleukin-1, interleukin-2, interferon-gamma and accessory cells. Eur J Immunol (1993) 1.36

[Immunologic diagnosis of human echinococcosis. (Personal report apropos of 400 cases)]. Pathol Biol (Paris) (1970) 1.36

Cytophilic binding of IgE to the macrophage. II. Immunologic release of lysosomal enzyme from macrophages by IgE and anti-IgE in the rat: a new mechanism of macrophage activation. Cell Immunol (1979) 1.36

Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists. Blood (1996) 1.35

Production of tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 (IL-1) in patients with AIDS. Enhanced level of TNF-alpha is related to a higher cytotoxic activity. Clin Exp Immunol (1989) 1.35

Eosinophil-dependent cytotoxicity in rat schistosomiasis. Involvement of IgG2a antibody and role of mast cells. Eur J Immunol (1978) 1.33

The receptor for IgE on blood platelets. Eur J Immunol (1986) 1.32

Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites. Exp Parasitol (1990) 1.32

IgA antibodies to a protective antigen in human Schistosomiasis mansoni. J Immunol (1993) 1.30

Common cis-acting elements critical for the expression of several genes of Toxoplasma gondii. Mol Microbiol (1996) 1.30

Eosinophilic gastroenteritis: ultrastructural evidence for a selective release of eosinophil major basic protein. Clin Exp Immunol (1988) 1.29

Heterogeneity of human eosinophils. II. Variability of respiratory burst activity related to cell density. Clin Exp Immunol (1984) 1.28

Cytotoxicity of human and baboon mononuclear phagocytes against schistosomula in vitro: induction by immune complexes containing IgE and Schistosoma mansoni antigens. Clin Exp Immunol (1978) 1.26

Early neutrophil alveolitis after antigen inhalation in hypersensitivity pneumonitis. Chest (1985) 1.25

Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV. Biochem J (1995) 1.24

Inhibition of lymphocyte proliferation by factor(s) produced by Schistosoma mansoni. Eur J Immunol (1977) 1.24

Macrophage triggering by aggregated immunoglobulins. I. Delayed effect of IgG aggregates or immune complexes. J Immunol (1981) 1.24

Evaluation of the enzyme-linked immunosorbent assay (ELISA) and other serological tests for the diagnosis of toxoplasmosis. Bull World Health Organ (1980) 1.23

Cytophilic binding of IgE to the macrophage. I. Binding characteristics of IgE on the surface of macrophages in the rat. Cell Immunol (1979) 1.23

Symptomatic hyperlactataemia: an emerging complication of antiretroviral therapy. AIDS (2000) 1.23

Immunoglobulin E and effector cells in schistosomiasis. Science (1994) 1.22

Is PCR a useful tool for the diagnosis of tuberculosis in 1995? Tuber Lung Dis (1995) 1.22

Subgenomic mRNA in OK10 defective leukemia virus-transformed cells. J Virol (1982) 1.22

Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes. J Exp Med (1999) 1.22

Molecular characterization of a dense granule antigen (Gra 2) associated with the network of the parasitophorous vacuole in Toxoplasma gondii. Mol Biochem Parasitol (1993) 1.22

Circulating immune complexes in schistosomiasis. Immunology (1977) 1.20

Major surface protein of Toxoplasma gondii (p30) contains an immunodominant region with repetitive epitopes. Eur J Immunol (1985) 1.20

Similarities between the primary structures of two distinct major surface proteins of Toxoplasma gondii. J Biol Chem (1994) 1.20

In vitro and in vivo effector function of rat IgG2a monoclonal anti-S. mansoni antibodies. J Immunol (1982) 1.19

Rat mast cell-eosinophil interaction in antibody-dependent eosinophil cytotoxicity to Schistosoma mansoni schistosomula. J Immunol (1978) 1.19

Cytophilic IgE on human blood and tissue eosinophils: detection by flow microfluorometry. J Immunol (1985) 1.18

Dipetalonema viteae in hamsters: effect of antiserum or immunization with parasite extracts on production of microfilariae. Parasitology (1978) 1.18

Arsenic-interferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation. Blood (2000) 1.18

Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella. Proc Natl Acad Sci U S A (1994) 1.16

Tumor necrosis factor alpha and interleukin-6 production by human mononuclear phagocytes from allergic asthmatics after IgE-dependent stimulation. Am Rev Respir Dis (1992) 1.16

Trypanosoma cruzi infection inhibited by peptides modeled from a fibronectin cell attachment domain. Science (1986) 1.15

Recognition of Toxoplasma gondii excreted and secreted antigens by human sera from acquired and congenital toxoplasmosis: identification of markers of acute and chronic infection. Clin Exp Immunol (1988) 1.15

Incidence of primary opportunistic infections in two human immunodeficiency virus-infected French clinical cohorts. Int J Epidemiol (2001) 1.15