Published in Proc Natl Acad Sci U S A on June 24, 1997
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc Natl Acad Sci U S A (1998) 3.24
Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc Natl Acad Sci U S A (2003) 2.48
Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. Proc Natl Acad Sci U S A (2001) 2.38
Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J Biol Chem (2000) 2.12
Identification of a photoreceptor cell-specific nuclear receptor. Proc Natl Acad Sci U S A (1999) 1.88
Identification of an endogenous ligand bound to a native orphan nuclear receptor. PLoS One (2009) 1.70
Were vertebrates octoploid? Philos Trans R Soc Lond B Biol Sci (2002) 1.62
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation. Biochim Biophys Acta (2011) 1.60
Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio). J Lipid Res (2009) 1.58
Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol (2001) 1.57
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1. Mol Cell Biol (1999) 1.40
Xenobiotic detoxification in the nematode Caenorhabditis elegans. J Exp Zool A Comp Exp Biol (2006) 1.36
Estrogen receptor beta in the brain: from form to function. Brain Res Rev (2007) 1.33
Explosive lineage-specific expansion of the orphan nuclear receptor HNF4 in nematodes. J Mol Evol (2005) 1.31
Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol. Mol Cell Biol (2003) 1.25
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. PLoS Biol (2010) 1.15
Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO. Biochemistry (2009) 1.13
Selective androgen receptor modulators in preclinical and clinical development. Nucl Recept Signal (2008) 1.11
Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and noradrenergic neuronal development. BMC Dev Biol (2007) 1.08
NUREBASE: database of nuclear hormone receptors. Nucleic Acids Res (2002) 1.08
Independent elaboration of steroid hormone signaling pathways in metazoans. Proc Natl Acad Sci U S A (2009) 1.07
Regulatory evolution and the origin of the bilaterians. Proc Natl Acad Sci U S A (2000) 1.07
The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. Proc Natl Acad Sci U S A (2001) 1.05
Hormone-activated estrogen receptors in annelid invertebrates: implications for evolution and endocrine disruption. Endocrinology (2008) 1.04
Nuclear receptor complement of the cnidarian Nematostella vectensis: phylogenetic relationships and developmental expression patterns. BMC Evol Biol (2009) 1.01
Nuclear receptors of the honey bee: annotation and expression in the adult brain. Insect Mol Biol (2006) 1.00
Creation and discovery of ligand-receptor pairs for transcriptional control with small molecules. Proc Natl Acad Sci U S A (2004) 0.99
Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease. Comp Hepatol (2003) 0.97
The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition. Dev Biol (2010) 0.97
Glucocorticoid-induced apoptosis of healthy and malignant lymphocytes. Prog Brain Res (2010) 0.96
Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2. J Biol Chem (1999) 0.95
Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors. PPAR Res (2013) 0.94
The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells. Mol Cell Biol (2008) 0.94
Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor. EMBO J (2007) 0.93
Complete sequence of the amphioxus (Branchiostoma lanceolatum) mitochondrial genome: relations to vertebrates. Nucleic Acids Res (1998) 0.92
Intrinsic disorder in nuclear hormone receptors. J Proteome Res (2008) 0.92
Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect. Proc Natl Acad Sci U S A (2008) 0.92
An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution. BMC Evol Biol (2008) 0.91
Retinoic acid X receptor in the diploblast, Tripedalia cystophora. Proc Natl Acad Sci U S A (1998) 0.90
Sex steroid receptor evolution and signalling in aquatic invertebrates. Ecotoxicology (2007) 0.89
Evolutionary history and functional characterization of androgen receptor genes in jawed vertebrates. Endocrinology (2009) 0.89
Sex steroids and potential mechanisms of non-genomic endocrine disruption in invertebrates. Ecotoxicology (2007) 0.89
A critical review of methods for comparing estrogenic activity of endogenous and exogenous chemicals in human milk and infant formula. Environ Health Perspect (2003) 0.89
Studying non-mammalian models? Not a fool's ERRand! Trends Endocrinol Metab (2006) 0.88
Nuclear hormone receptor signaling in amphioxus. Dev Genes Evol (2008) 0.88
Conservation and divergence of NF-Y transcriptional activation function. Nucleic Acids Res (1998) 0.88
Evolution of retinoid and steroid signaling: vertebrate diversification from an amphioxus perspective. Genome Biol Evol (2011) 0.86
Cloning and developmental expression of five estrogen-receptor related genes in the zebrafish. Dev Genes Evol (2004) 0.86
Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1. Proc Natl Acad Sci U S A (2001) 0.85
Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX. Mol Cell Biol (2000) 0.83
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. Xenobiotica (2009) 0.83
Impact of tributyltin and triphenyltin on ivory shell (Babylonia japonica) populations. Environ Health Perspect (2006) 0.82
The evolution of protein interaction networks in regulatory proteins. Comp Funct Genomics (2004) 0.81
Structural and functional analysis of the amphioxus IGFBP gene uncovers ancient origin of IGF-independent functions. Endocrinology (2013) 0.79
Nuclear hormone receptors in parasitic helminths. Mol Cell Endocrinol (2010) 0.79
A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor α. J Mol Graph Model (2014) 0.77
A canonical cation-π interaction stabilizes the agonist conformation of estrogen-like nuclear receptors. Eur Biophys J (2010) 0.77
IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING. Nucl Receptor Res (2014) 0.77
The role of nuclear receptors in the kidney in obesity and metabolic syndrome. Genes Nutr (2012) 0.77
3D model of lamprey estrogen receptor with estradiol and 15alpha-hydroxy-estradiol. PLoS One (2009) 0.76
Establishment of a polyclonal antibody against the retinoid X receptor of the rock shell Thais clavigera and its application to rock shell tissues for imposex research. Ecotoxicology (2009) 0.76
Hormonal signaling in cnidarians: do we understand the pathways well enough to know whether they are being disrupted? Ecotoxicology (2007) 0.75
Unique functional properties of a member of the Fushi Tarazu-Factor 1 family from Schistosoma mansoni. Biochem J (2004) 0.75
Conservation of estrogen receptor function in invertebrate reproduction. BMC Evol Biol (2017) 0.75
Controlling Sulfuryl-Transfer Biology. Cell Chem Biol (2016) 0.75
Nuclear receptor nhr-48 is required for pathogenicity of the second stage (J2) of the plant parasite Meloidogyne incognita. Sci Rep (2016) 0.75
Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution. PeerJ (2017) 0.75
'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res (1991) 19.71
The RXR heterodimers and orphan receptors. Cell (1995) 12.33
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc Natl Acad Sci U S A (1992) 5.28
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev (1992) 4.69
Gene duplications and the origins of vertebrate development. Dev Suppl (1994) 3.98
MUST, a computer package of Management Utilities for Sequences and Trees. Nucleic Acids Res (1993) 3.82
Evolution of the nuclear receptor gene superfamily. EMBO J (1992) 3.55
The yeast genome project: what did we learn? Trends Genet (1996) 3.53
Dopaminergic and ligand-independent activation of steroid hormone receptors. Science (1991) 2.33
Transcription factors 3: nuclear receptors. Protein Profile (1995) 2.02
An analysis of the origin of metazoans, using comparisons of partial sequences of the 28S RNA, reveals an early emergence of triploblasts. EMBO J (1991) 1.37
An evolutionary view of drug-receptor interaction: the bioamine receptor family. Trends Pharmacol Sci (1995) 1.33
Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states. Mol Cell Biol (1996) 1.32
The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors. Mol Endocrinol (1992) 1.21
Ligand occupancy is not required for vitamin D receptor and retinoid receptor-mediated transcriptional activation. Mol Endocrinol (1995) 1.03
The sound of silence. Nature (1995) 0.86
Phylogeny of the steroid receptor superfamily. Mol Phylogenet Evol (1994) 0.86
Dinucleotide biases in the platyhelminth Schistosoma mansoni. Int J Parasitol (1994) 0.84
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation. Nature (1979) 5.75
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med (1992) 5.29
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature (1984) 4.35
Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. Immunol Today (1991) 3.79
The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation. Nature (1990) 3.74
Evolution of the nuclear receptor gene superfamily. EMBO J (1992) 3.55
Treatment of hepatic hydatid disease with mebedazole: preliminary results in four cases. Br Med J (1977) 3.10
Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants. Virology (1977) 2.99
[Immunoenzymologic diagnosis of parasitic diseases. II. Quantitative immunoenzymology]. Lille Med (1976) 2.74
Nucleotide sequence of the human c-myc locus: provocative open reading frame within the first exon. EMBO J (1984) 2.55
The ets gene family. Trends Biochem Sci (1992) 2.48
Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res (1993) 2.47
Chromosomal localization of the human proto-oncogene c-ets. Nature (1984) 2.35
Immunity after treatment of human schistosomiasis: association between IgE antibodies to adult worm antigens and resistance to reinfection. Eur J Immunol (1992) 2.33
Specific IgE antibodies in immune adherence of normal macrophages to Schistosoma mansoni schistosomules. Nature (1975) 2.19
Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia. Int Arch Allergy Appl Immunol (1983) 2.17
Sequencing the erbA gene of avian erythroblastosis virus reveals a new type of oncogene. Science (1984) 2.12
A new function for platelets: IgE-dependent killing of schistosomes. Nature (1983) 2.11
Ancient DNA analysis reveals divergence of the cave bear, Ursus spelaeus, and brown bear, Ursus arctos, lineages. Curr Biol (2001) 2.11
Management of chronic obstructive pulmonary disease in the twenty-first century. Intern Med J (2001) 2.08
Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med (1986) 2.03
Transcription factors 3: nuclear receptors. Protein Profile (1995) 2.02
Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med (1994) 2.01
An ancestral whole-genome duplication may not have been responsible for the abundance of duplicated fish genes. Curr Biol (2001) 2.01
Spatial and temporal pattern of cellular myc oncogene expression in developing human placenta: implications for embryonic cell proliferation. Cell (1984) 1.99
High-affinity IgE receptor on eosinophils is involved in defence against parasites. Nature (1994) 1.95
Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein. Proc Natl Acad Sci U S A (1986) 1.89
Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease. J Exp Med (1992) 1.88
Role of IgE receptors in effector function of human eosinophils. J Immunol (1984) 1.87
The human DNA locus related to the oncogene myb of avian myeloblastosis virus (AMV): molecular cloning and structural characterization. EMBO J (1983) 1.87
Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection. J Exp Med (2001) 1.79
The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. Immunity (1997) 1.78
Activity of respiratory pump and upper airway muscles during sleep onset. J Appl Physiol (1985) (1998) 1.74
Molecular crosstalk in host-parasite relationships: schistosome- and leech-host interactions. Parasitol Today (2000) 1.73
IgA antibodies against P30 as markers of congenital and acute toxoplasmosis. Lancet (1988) 1.70
Relationship between replication of simian virus 40 DNA and specific events of the host cell cycle. J Virol (1973) 1.67
Molecular cloning of the avian acute transforming retrovirus MH2 reveals a novel cell-derived sequence (v-mil) in addition to the myc oncogene. EMBO J (1983) 1.64
Serodiagnosis of toxoplasma infection using a purified parasite protein (P30). Clin Exp Immunol (1985) 1.64
Fc receptors for IgE on human and rat eosinophils. J Immunol (1981) 1.63
Evidence for IgE-dependent cytotoxicity by rat eosinophils. J Immunol (1981) 1.61
Transcriptional targets shared by estrogen receptor- related receptors (ERRs) and estrogen receptor (ER) alpha, but not by ERbeta. EMBO J (1999) 1.58
v-mil induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages. Cell (1986) 1.52
Cost-effective method for bedside insertion of vena caval filters in trauma patients. J Trauma (1997) 1.50
Euteleost fish genomes are characterized by expansion of gene families. Genome Res (2001) 1.50
Molecular cloning of a protective antigen of schistosomes. Nature (1987) 1.49
The distribution of endogenous chicken retrovirus sequences in the DNA of galliform birds does not coincide with avian phylogenetic relationships. Cell (1979) 1.49
Schistosoma mansoni schistosomula reduce E-selectin and VCAM-1 expression in TNF-alpha-stimulated lung microvascular endothelial cells by interfering with the NF-kappaB pathway. Eur J Immunol (1999) 1.49
Interaction between IgE complexes and macrophages in the rat: a new mechanism of macrophage activation. Eur J Immunol (1977) 1.48
Analysis of the Mycobacterium tuberculosis 85A antigen promoter region. J Bacteriol (1995) 1.48
Quantitative determination of specific IgE antibodies to Echinococcus granulosus and IgE levels in sera from patients with hydatid disease. Immunology (1975) 1.47
Increased secretion of tumor necrosis factor alpha and interleukin-6 by alveolar macrophages consecutive to the development of the late asthmatic reaction. J Allergy Clin Immunol (1991) 1.46
The Ets family of proteins: weak modulators of gene expression in quest for transcriptional partners. Crit Rev Oncog (1994) 1.45
[Antigenic structure of helminthes. Immunological aspects of the host-parasite relationship]. Pathol Biol (1968) 1.45
Zinc tolerance and hyperaccumulation are genetically independent characters. Proc Biol Sci (1999) 1.44
Rearrangements of genetic material in Escherichia coli as observed on the bacteriophage P1 plasmid. Cold Spring Harb Symp Quant Biol (1979) 1.44
Involvement of immunoglobulin E in the secretory processes of alveolar macrophages from asthmatic patients. J Clin Invest (1983) 1.44
Enzyme release and superoxide anion production by human alveolar macrophages stimulated with immunoglobulin E. Clin Exp Immunol (1980) 1.42
Receptor for IgG(Fc) and human beta2-microglobulin on S. mansoni schistosomula. Nature (1979) 1.41
[Results of total hip replacement (control of the 1962--1968 operated cases)]. Z Orthop Ihre Grenzgeb (1972) 1.41
Tracking the origins of the cave bear (Ursus spelaeus) by mitochondrial DNA sequencing. Proc Natl Acad Sci U S A (1994) 1.41
Schistosomiasis co-infection in humans influences inflammatory markers in uncomplicated Plasmodium falciparum malaria. Parasite Immunol (2005) 1.40
A purified 28,000 dalton protein from Schistosoma mansoni adult worms protects rats and mice against experimental schistosomiasis. J Immunol (1987) 1.39
Functional role of human IgG subclasses in eosinophil-mediated killing of schistosomula of Schistosoma mansoni. J Immunol (1989) 1.39
DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss. Biochim Biophys Acta (2000) 1.38
Fibronectin receptors on Trypanosoma cruzi trypomastigotes and their biological function. Nature (1984) 1.38
The cellular oncogenes c-myc, c-myb and c-erb are transcribed in defined types of avian hematopoietic cells. Exp Cell Res (1983) 1.38
The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates. J Biol Chem (1998) 1.38
CD3-mediated apoptosis of human medullary thymocytes and activated peripheral T cells: respective roles of interleukin-1, interleukin-2, interferon-gamma and accessory cells. Eur J Immunol (1993) 1.36
[Immunologic diagnosis of human echinococcosis. (Personal report apropos of 400 cases)]. Pathol Biol (Paris) (1970) 1.36
Cytophilic binding of IgE to the macrophage. II. Immunologic release of lysosomal enzyme from macrophages by IgE and anti-IgE in the rat: a new mechanism of macrophage activation. Cell Immunol (1979) 1.36
Production of tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 (IL-1) in patients with AIDS. Enhanced level of TNF-alpha is related to a higher cytotoxic activity. Clin Exp Immunol (1989) 1.35
Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol Cell (1993) 1.34
Evolutionary rates of duplicate genes in fish and mammals. Mol Biol Evol (2001) 1.34
How many nuclear hormone receptors are there in the human genome? Trends Genet (2001) 1.34
Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina. Mol Cell Biol (1993) 1.33
c-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans. Am J Pathol (1992) 1.33
Eosinophil-dependent cytotoxicity in rat schistosomiasis. Involvement of IgG2a antibody and role of mast cells. Eur J Immunol (1978) 1.33
Ligand binding and nuclear receptor evolution. Bioessays (2000) 1.33
The receptor for IgE on blood platelets. Eur J Immunol (1986) 1.32
Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites. Exp Parasitol (1990) 1.32
The Ets family member Erg gene is expressed in mesodermal tissues and neural crests at fundamental steps during mouse embryogenesis. Mech Dev (2000) 1.30
IgA antibodies to a protective antigen in human Schistosomiasis mansoni. J Immunol (1993) 1.30
Activation of the osteopontin promoter by the orphan nuclear receptor estrogen receptor related alpha. Cell Growth Differ (1998) 1.30
Common cis-acting elements critical for the expression of several genes of Toxoplasma gondii. Mol Microbiol (1996) 1.30
Eosinophilic gastroenteritis: ultrastructural evidence for a selective release of eosinophil major basic protein. Clin Exp Immunol (1988) 1.29
Retrieval of renal function by revascularization. Study of preoperative outcome predictors. Ann Surg (1985) 1.29
Heterogeneity of human eosinophils. II. Variability of respiratory burst activity related to cell density. Clin Exp Immunol (1984) 1.28
Transcriptional activities of the orphan nuclear receptor ERR alpha (estrogen receptor-related receptor-alpha). Mol Endocrinol (1999) 1.28
[Amplification of mitochondrial DNA fragments from ancient human teeth and bones]. C R Acad Sci III (1990) 1.27
Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver. Gene (1994) 1.26
The chordate amphioxus: an emerging model organism for developmental biology. Cell Mol Life Sci (2004) 1.26
Circadian regulation of diverse gene products revealed by mRNA expression profiling of synchronized fibroblasts. J Biol Chem (2001) 1.26
Cytotoxicity of human and baboon mononuclear phagocytes against schistosomula in vitro: induction by immune complexes containing IgE and Schistosoma mansoni antigens. Clin Exp Immunol (1978) 1.26
Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene. Nucleic Acids Res (1991) 1.26
Detection and enumeration of transformation-defective strains of avian sarcoma virus with molecular hybridization. Virology (1977) 1.25
Characterization of the oncogene (erb) of avian erythroblastosis virus and its cellular progenitor. J Virol (1981) 1.24