Published in J Exp Med on December 01, 1958
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol (1963) 29.15
CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM. Proc Natl Acad Sci U S A (1965) 9.53
Steps in the neoplastic transformation of hamster embryo cells by polyoma virus. Proc Natl Acad Sci U S A (1963) 7.89
Morphological transformation of Chinese hamster cells by dibutyryl adenosine cyclic 3':5'-monophosphate and testosterone. Proc Natl Acad Sci U S A (1971) 6.12
Functional correlation between cell adhesive properties and some cell surface proteins. J Cell Biol (1977) 4.97
Genetic analysis of simian virus 40. 3. Characterization of a temperature-sensitive mutant blocked at an early stage of productive infection in monkey cells. J Virol (1972) 4.76
Cellular kinetics associated with the development of acquired cellular resistance. J Exp Med (1969) 3.94
LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. II. CELLS FROM THE CHINESE HAMSTER OVARY GROWN IN SUSPENSION CULTURE. Biophys J (1964) 3.49
THE SOMATIC CHOMOSOMES OF MAN. Proc Natl Acad Sci U S A (1958) 3.33
Genetics of somatic mammalian cells. IV. Properties of Chinese hamster cell mutants with respect to the requirement for proline. Genetics (1967) 3.03
A human skin culture technique used for cytological examinations. Br J Exp Pathol (1960) 2.86
Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med (2004) 2.67
Early events in polyoma virus infection: attachment, penetration, and nuclear entry. J Virol (1976) 2.65
Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis. J Virol (1992) 2.25
Types and frequencies of human chromosome aberrations induced by x-rays. Proc Natl Acad Sci U S A (1961) 2.16
Sex chromatin, sex chromosomes and sex anomalies. Can Med Assoc J (1960) 2.12
Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells. J Cell Biol (1980) 2.12
Genetics of somatic mammalian cells: lethal antigens as genetic markers for study of human linkage groups. Proc Natl Acad Sci U S A (1971) 2.00
Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site. J Cell Biol (1995) 1.90
ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY FORMING CELLS AFTER ANTIGEN. J Exp Med (1965) 1.79
Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells. J Cell Biol (1984) 1.70
The submembranous fibrils of human blood platelets. J Cell Biol (1970) 1.70
THE REQUIREMENT FOR HYDROCORTISONE IN ANTIBODY-FORMING TISSUE CULTIVATED IN SERUM-FREE MEDIUM. J Exp Med (1964) 1.67
A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase. Proc Natl Acad Sci U S A (1973) 1.65
Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines. Cytotechnology (2007) 1.63
Synergistic action of streptomycin with other antibiotics of intracellular Brucella abortus in vitro. J Bacteriol (1962) 1.60
A major transactivator of varicella-zoster virus, the immediate-early protein IE62, contains a potent N-terminal activation domain. J Virol (1993) 1.59
Cellular differentiation in colonies derived from single cells platings of freshly isolated chick embryo muscle cells. Proc Natl Acad Sci U S A (1961) 1.58
Immunological memory in mice. I. Physical separation and partial characterization of memory cells for different immunoglobulin classes from each other and from antibody-producing cells. J Exp Med (1970) 1.57
Mouse-human heterokaryons support efficient human immunodeficiency virus type 1 assembly. J Virol (2001) 1.55
The susceptibility of differentiating muscle clones to Rous sarcoma virus. Proc Natl Acad Sci U S A (1966) 1.55
The interaction of mammalian cells with antibodies. I. J Exp Med (1961) 1.53
In vivo expression of mammalian BiP ATPase mutants causes disruption of the endoplasmic reticulum. Mol Biol Cell (1995) 1.53
Do you know the sex of your cells? Am J Physiol Cell Physiol (2013) 1.49
The effect of cell-to-cell contact on the surface morphology of Chinese hamster ovary cells. J Cell Biol (1973) 1.44
Biochemically differentiated neoplastic clone of Schwann cells. Proc Natl Acad Sci U S A (1972) 1.43
Microfibrils of blood platelets: their relationship TO MICROTUBULES AND THE CONTRACTILE PROTEIN. J Clin Invest (1969) 1.43
THE SOMATIC CHROMOSOMAL CONSTITUTION OF SOME HUMAN SUBJECTS WITH GENETIC DEFECTS. Proc Natl Acad Sci U S A (1959) 1.42
Cell cycle-specific changes in histone phosphorylation associated with cell proliferation and chromosome condensation. J Cell Biol (1974) 1.40
Gibbon ape leukemia virus and the amphotropic murine leukemia virus 4070A exhibit an unusual interference pattern on E36 Chinese hamster cells. J Virol (1993) 1.35
THE HUMAN CHROMOSOMAL SATELLITES IN NORMAL PERSONS AND IN TWO PATIENTS WITH MARFAN'S SYNDROME. Proc Natl Acad Sci U S A (1960) 1.32
Growth and division of single cells of higher plants in vitro. J Gen Physiol (1960) 1.31
Next-generation sequencing of the CHO cell transcriptome. BMC Proc (2011) 1.29
THE FREQUENCY OF SISTER CHROMATID EXCHANGES FOLLOWING EXPOSURE TO VARYING DOSES OF H3-THYMIDINE OR X-RAYS. J Cell Biol (1964) 1.27
The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner. Nucleic Acids Res (1997) 1.26
Surface antigens of mammalian cells as genetic markers. II. J Exp Med (1973) 1.25
Construction of a normalized cDNA library by introduction of a semi-solid mRNA-cDNA hybridization system. Nucleic Acids Res (1994) 1.25
Adhesion of phospholipid vesicles to Chinese hamster fibroblasts. Role of cell surface proteins. J Cell Biol (1977) 1.23
Properties of acatalasic cells growing in vitro. J Exp Med (1962) 1.22
Role of microtubules in low density lipoprotein processing by cultured cells. J Clin Invest (1979) 1.18
Metabolic event involved in the bactericidal activity of normal mouse macrophages. Infect Immun (1971) 1.17
A ubiquitous beta-tubulin disrupts microtubule assembly and inhibits cell proliferation. Mol Biol Cell (2004) 1.15
Studies on cell lines developed from the tissues of patients with galactosemia. J Exp Med (1961) 1.15
Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes. J Cell Biol (1986) 1.14
ANTIGENIC SPECIFICITIES ACQUIRED FROM THE GROWTH MEDIUM BY CELLS IN TISSUE CULTURE. Immunology (1963) 1.14
Astrocyte senescence as a component of Alzheimer's disease. PLoS One (2012) 1.11
Inhibition of group B arbovirus antigen production and replication in cells enucleated with cytochalasin B. J Virol (1975) 1.09
EFFECT OF CURRENT ON TRANSMEMBRANE POTENTIALS IN CULTURED CHICK HEART CELLS. J Gen Physiol (1964) 1.08
The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein. Cytotechnology (2002) 1.08
Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2. Nucleic Acids Res (2002) 1.05
MULTIPLICATION OF BRUCELLA IN CULTURED LYMPHOID AND NONLYMPHOID CELLS. J Bacteriol (1964) 1.02
PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome. J Cell Biol (2012) 1.01
Heritability and control of differentiated function in cultured cells. J Gen Physiol (1963) 0.99
Differential modulation of doxorubicin toxicity to multidrug and intrinsically drug resistant cell lines by anti-oestrogens and their major metabolites. Br J Cancer (1993) 0.98
First CHO genome. Nat Biotechnol (2011) 0.97
Cell elongation in the cultured embryonic chick lens epithelium with and without protein synthesis. Involvement of microtubules. J Cell Biol (1972) 0.97
Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate. BMC Genomics (2012) 0.96
Designer TGFβ superfamily ligands with diversified functionality. PLoS One (2011) 0.96
Standardization of human diploid cell cultivation. Appl Microbiol (1970) 0.95
Phosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirus. Antimicrob Agents Chemother (2002) 0.94
A correlation between membrane fluidity and the critical temperature for cell adhesion. J Cell Biol (1976) 0.93
Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability. Radiat Res (2010) 0.93
Relationship between chromosomal changes and alterations in the behaviour of a strain of human synovial cells during its life history in vitro. Ann Rheum Dis (1968) 0.93
Recent advances in mammalian protein production. FEBS Lett (2013) 0.93
Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells. Mol Cell Biol (1988) 0.93
Agrin-induced reorganization of extracellular matrix components on cultured myotubes: relationship to AChR aggregation. J Cell Biol (1990) 0.93
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation. Eur J Immunol (2011) 0.93
Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance. J Biol Chem (2009) 0.92
The chromosome complements of human somatic cells. Am J Hum Genet (1960) 0.90
Malignant transformation and tumor promoter treatment increase levels of a transcript for a secreted glycoprotein. Mol Cell Biol (1985) 0.90
Cell cycle parameters of Chinese hamster ovary cells during exponential, polyamine-limited growth. Mol Cell Biol (1981) 0.90
Transcriptional initiation and postinitiation effects of murine leukemia virus long terminal repeat R-region sequences. J Virol (1991) 0.90
Sites of nucleolus production in cultured Chinese hamster cells. J Cell Biol (1969) 0.90
The Gardner syndrome: a cell culture study on kindred 109. J Med Genet (1978) 0.89
Schwann cell proliferation and localized proteolysis: expression of plasminogen-activator activity predominates in the proliferating cell populations. Proc Natl Acad Sci U S A (1984) 0.89
Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines. PLoS One (2014) 0.88
Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation. J Cell Biol (1995) 0.88
Regulation of microtubule assembly in cultured fibroblasts. J Cell Biol (1980) 0.88
Effects of cyclic AMP and Sephadex fractions of chick embryo extract on cloned retinal pigmented epithelium in tissue culture. J Cell Biol (1974) 0.88
Decreased tumorigenicity correlates with expression of altered cell surface carbohydrates in Lec9 CHO cells. Mol Cell Biol (1986) 0.88
Chinese hamster ovary cell population density affects intracellular concentrations of calcium-dependent regulator and ability of regulator to inhibit adenylate cyclase activity. Proc Natl Acad Sci U S A (1979) 0.87
Inhibition of induced aldosterone biosynthesis with a specific antagonist of angiotensin II. Proc Natl Acad Sci U S A (1974) 0.87
Maintenance of serum immunoglobulin G antibodies to Epstein-Barr virus (EBV) nuclear antigen 2 in healthy individuals from different age groups in a Japanese population with a high childhood incidence of asymptomatic primary EBV infection. Clin Diagn Lab Immunol (2004) 0.86
Repair DNA synthesis in differentiated embryonic muscle cells. J Cell Biol (1972) 0.86
Human chromosome 13 compensates a DNA repair defect in UV-sensitive mouse cells by mouse--human cell hybridization. Proc Natl Acad Sci U S A (1983) 0.85
Expression of chicken DEC205 reflects the unique structure and function of the avian immune system. PLoS One (2013) 0.85
Gene inactivation as a mechanism for the expression of recessive phenotypes. Am J Hum Genet (1989) 0.84
CHO microRNA engineering is growing up: recent successes and future challenges. Biotechnol Adv (2013) 0.84
Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem (2015) 0.83
Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer. J Exp Med (1956) 22.68
Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture. J Exp Med (1958) 8.81
Clonal growth in vitro of human cells with fibroblastic morphology; comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs. J Exp Med (1957) 6.35
GENETICS OF SOMATIC MAMMALIAN CELLS : I. DEMONSTRATION OF THE EXISTENCE OF MUTANTS WITH DIFFERENT GROWTH REQUIREMENTS IN A HUMAN CANCER CELL STRAIN (HELA). J Exp Med (1956) 4.57
Neoplastic changes developing in epithelial cell lines derived from normal persons. Science (1956) 3.81
A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis. Nature (1949) 3.70
ACTION OF RADIATION ON MAMMALIAN CELLS III. RELATIONSHIP BETWEEN REPRODUCTIVE DEATH AND INDUCTION OF CHROMOSOME ANOMALIES BY X-IRRADIATION OF EUPLOID HUMAN CELLS IN VITRO. Proc Natl Acad Sci U S A (1958) 3.48
Some aspects of the constitution and behavior of normal and malignant cells maintained in continuous culture. Harvey Lect (1956) 3.04
Molecular Growth Requirements of Single Mammalian Cells. Science (1957) 2.77
The deoxyribonucleic acid content of individual rat cell nuclei. Exp Cell Res (1954) 2.09
Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer. J Exp Med (1956) 22.68
Action of x-rays on mammalian cells. J Exp Med (1956) 13.53
The mechanism of virus attachment to host cells. I. The role of ions in the primary reaction. J Exp Med (1951) 10.50
Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture. J Exp Med (1958) 8.81
LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. I. A METHOD FOR LOCALIZING METABOLIC EVENTS WITHIN THE LIFE CYCLE, AND ITS APPLICATION TO THE ACTION OF COLCEMIDE AND SUBLETHAL DOSES OF X-IRRADIATION. Biophys J (1963) 8.65
Clonal growth in vitro of human cells with fibroblastic morphology; comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs. J Exp Med (1957) 6.35
Clonal growth in vitro of epithelial cells from normal human tissues. J Exp Med (1956) 5.38
The first two steps of the invasion of host cells by bacterial viruses. II. J Exp Med (1951) 5.01
Action of x-rays on mammalian cells. II. Survival curves of cells from normal human tissues. J Exp Med (1957) 4.23
LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. II. CELLS FROM THE CHINESE HAMSTER OVARY GROWN IN SUSPENSION CULTURE. Biophys J (1964) 3.49
The first steps of virus invasion. Cold Spring Harb Symp Quant Biol (1953) 3.36
Mechanism of cell wall penetration by viruses. I. An increase in host cell permeability induced by bacteriophage infection. J Exp Med (1954) 2.75
The mechanism of virus attachment to host cells. IV. Physicochemical studies on virus and cell surface groups. Arch Biochem Biophys (1954) 2.74
The use of x-irradiated HeLa cell giants to detect latent virus in mammalian cells. Virology (1957) 2.34
Mechanism of cell wall penetration by viruses. II. Demonstration of cyclic permeability change accompanying virus infection of Escherichia coli B cells. J Exp Med (1955) 2.28
Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 HeLa cell produced by low doses of x-rays. Proc Natl Acad Sci U S A (1961) 1.95
STUDIES OF THE LIFE CYCLE OF MAMMALIAN CELLS. Cold Spring Harb Symp Quant Biol (1964) 1.88
The interaction of mammalian cells with antibodies. I. J Exp Med (1961) 1.53
An absolute method for assay of virus hemagglutinins. J Exp Med (1953) 1.49
SEX CHROMATIN IN NEWBORNS: PRESUMPTIVE EVIDENCE FOR EXTERNAL FACTORS IN HUMAN NONDISJUNCTON. Science (1965) 1.45
The hydrolytic products of fetuin. Arch Biochem Biophys (1962) 1.37
Host-cell interaction of animal viruses. I. Titration of cell-killing by viruses. Virology (1958) 1.33
The genetics of somatic mammalian cells. Adv Biol Med Phys (1957) 1.32
Some effects of inorganic ions on the active transport of phenol red by isolated kidney tubules of the flounder. J Cell Physiol (1952) 1.24
Familial primary amenorrhea due to testicular feminization: A human gene affecting sex differenctiation. Proc Soc Exp Biol Med (1960) 1.18
Date on the occurrence of hemoglobin C and other abnormal hemoglobins in some African populations. Am J Hum Genet (1956) 1.17
The action of ultraviolet radiation on mammalian cells as studied by single-cell techniques. Radiat Res (1960) 1.17
THE ASSAY OF GALACTOKINASE AND GALACTOSE-1-PHOSPHATE URIDYL TRANSFERASE ACTIVITY IN HUMAN ERYTHROCYTES. A PRESUMED TEST FOR HETEROZYGOUS CARRIERS OF THE GALACTOSEMIC DEFECT. J Exp Med (1963) 1.12
The lethal effect of relative humidity on air-borne bacteria. J Exp Med (1948) 1.11
The separate dental school library. Bull Med Libr Assoc (1952) 1.08
In vitro studies on the radiation biology of mammalian cells. Prog Biophys Mol Biol (1960) 1.04
Ataxia-telangiectasia presenting with craniostenosis. Arch Dis Child (1962) 1.00
A regulated incubator controlling CO2 concentration, humidity and temperature for use in animal cell culture. Proc Soc Exp Biol Med (1962) 0.99
Tuberculin hypersensitivity in tuberculous infants treated with isoniazid. N Engl J Med (1955) 0.98
Tuberculous meningitis in infants and children. AMA Am J Dis Child (1954) 0.97
Transmission and control of respiratory disease in army barracks. III. The suppression of dust-borne bacteria by oiling floors and bedclothes. J Infect Dis (1952) 0.96
Importance of bronchial involvement in primary tuberculosis of childhood. J Am Med Assoc (1951) 0.96
Cellular aspects of irradiation and aging in mammals. Fed Proc (1961) 0.93
Radiation and the human cell. Sci Am (1960) 0.92
THE ELECTROCARDIOGRAM DURING EXCHANGE TRANSFUSION. Arch Dis Child (1963) 0.85
EMERGENCY HYPOTHERMIA IN MENINGOCOCCAL MENINGITIS. Lancet (1965) 0.84
Quantitation of growth of mammalian cells. Harvey Lect (1961) 0.83
CELLULAR ASPECTS OF THE MAMMALIAN RADIATION SYNDROME: NUCLEATED CELL DEPLETION IN THE BONE MARROW. Proc Natl Acad Sci U S A (1964) 0.82
The human chromosomes. Am J Dis Child (1961) 0.80
Quantitative colonial growth of single mammalian cells. Ann N Y Acad Sci (1958) 0.78
Growth and genetics in somatic mammalian cells in vitro. J Cell Physiol Suppl (1958) 0.78
A proposed standard system of nomenclature of human mitotic chromosomes. JAMA (1960) 0.77
The effect of specific therapy in primary tuberculosis of the child. J Pediatr (1956) 0.75
[Not Available]. Bol Trimest Hosp Vina del Mar (1949) 0.75
The dispersion and control of triethylene glycol vapors for aerial disinfection. Ind Med Surg (1946) 0.75
Nutritional status of children; blood serum vitamin A and carotenoids. J Am Diet Assoc (1948) 0.75
Amino acids in turtle egg. Arch Biochem (1946) 0.75
Osteoarthritis of the hip. Can Med Assoc J (1949) 0.75
The tabloid newspaper as a medium of mass public venereal disease education. J Vener Dis Inf (1948) 0.75
Industrial and office hygiene. J R Inst Public Health (1963) 0.75
Atresia of the tricuspid valve with transposition of the great vessels. Am J Dis Child (1948) 0.75
Minor cyanide poisoning. J R Nav Med Serv (1956) 0.75
Pulmonary tuberculosis: the primary lesion; specific vs. nonspecific therapy. Pediatr Clin North Am (1957) 0.75
Studies in vapor-liquid equilibria; a new dynamic method for the determination of vapor pressures of liquids. J Phys Chem (1946) 0.75
The oil treatment of bedclothes for the control of dust-borne infection; principles underlying the development and use of a satisfactory oil-in-water emulsion. Am J Hyg (1946) 0.75
A modified radioiodine test for thyroid function. J Lab Clin Med (1952) 0.75
Proposed standard system of nomenclature of human mitotic chromosomes. N Engl J Med (1960) 0.75
A case of cyanide poisoning. J R Nav Med Serv (1959) 0.75
Concentrations of active isoniazid in serum and cerebrospinal fluid of patients with tuberculosis treated with isoniazid. Pediatrics (1958) 0.75
A housing survey in an Asiatic community. J R Nav Med Serv (1950) 0.75
Barrier creams and hand-cleansers in industry. J R Nav Med Serv (1961) 0.75
Human milk studies; ascorbic acid and dehydroascorbic acid in colostrum and mature human milk. Am J Dis Child (1945) 0.75
A source of error in the shipment and storage of plasma samples for alkaline phosphatase determination. J Lab Clin Med (1950) 0.75
Acute osteomyelitis of the superior maxilla in infants. J Mt Sinai Hosp N Y (1948) 0.75
Studies by the Commission on airborne infections on the disinfection of air by glycol vapors. J Bacteriol (1946) 0.75
The treatment of primary tuberculosis in infancy. J Pediatr (1955) 0.75
Electrocardiographic studies in experimental Chagas' disease in mice (Mus musculus). Tex Rep Biol Med (1958) 0.75
Metabolism of women during the reproductive cycle; the effect of multivitamin supplements on the secretion of vitamin A in human milk. J Am Diet Assoc (1948) 0.75
SELECTIVE ANGIOCARDIOGRAPHY FOR DIAGNOSIS OF CONGENITAL CARDIAC DEFECTS IN INFANCY. Am J Roentgenol Radium Ther Nucl Med (1965) 0.75
Special responsibilities of the medical school in view of the biological revolution. J Med Educ (1962) 0.75
Stimulation of the use of the dental library. Bull Med Libr Assoc (1953) 0.75
Molecular growth requirements of single mammalian cells. Science (1957) 0.75