Published in Proc Natl Acad Sci U S A on February 01, 1971
Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun (1974) 12.51
Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence. Proc Natl Acad Sci U S A (1975) 6.08
Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin. Infect Immun (1983) 5.03
Restoration of contact-inhibited growth to transformed cells by dibutyryl adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1971) 3.44
Isolation and characterization of myosin from cloned mouse fibroblasts. Proc Natl Acad Sci U S A (1972) 3.24
Further changes in differentiation state accompanying the conversion of Chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones. Proc Natl Acad Sci U S A (1971) 3.23
Changes in surface morphology of Chinese hamster ovary cells during the cell cycle. J Cell Biol (1973) 3.14
Membrane dynamics in the action of dibutyryl adenosine 3':5'-cyclic monophosphate and testosterone on mammalian cells. Proc Natl Acad Sci U S A (1972) 2.86
Isolation of a factor causing morphological changes of chinese hamster ovary cells from the culture filtrate of Vibrio parahaemolyticus. Infect Immun (1976) 2.56
Pleiotypic control by adenosine 3':5'-cyclic monophosphate: a model for growth control in animal cells. Proc Natl Acad Sci U S A (1973) 2.49
A scanning electron microscope study of surface features of viral and spontaneous transformants of mouse Balb-3T3 cells. J Cell Biol (1973) 2.30
Tubulin assembly sites and the organization of cytoplasmic microtubules in cultured mammalian cells. J Cell Biol (1981) 2.21
Isolation, characterization, and mapping of Escherichia coli mutants blocked in the synthesis of ornithine decarboxylase. J Bacteriol (1975) 2.07
Cyclic amp and cell morphology in cultured fibroblasts. Effects on cell shape, microfilament and microtubule distribution, and orientation to substratum. J Cell Biol (1975) 1.82
Pleiotypic control by cyclic AMP: interaction with cyclic GMP and possible role of microtubules. Proc Natl Acad Sci U S A (1973) 1.78
Prostaglandin E 1 effects on adenosine 3':5'-cyclic monophosphate concentration and phosphodiesterase activity in fibroblasts (mouse L cells-tissue culture-enzyme kinetics-prostaglandin homologues). Proc Natl Acad Sci U S A (1972) 1.68
Cytochalasin separates microtubule disassembly from loss of asymmetric morphology. J Cell Biol (1981) 1.63
Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells. J Cell Biol (1981) 1.58
Cyclic AMP, the microtubule-microfilament system, and cancer. Proc Natl Acad Sci U S A (1977) 1.50
Effect of insulin on the growth pattern and adenylate cyclase activity of BHK fibroblasts. Proc Natl Acad Sci U S A (1973) 1.45
Antioncogenic effect of adenovirus E1A in human tumor cells. Proc Natl Acad Sci U S A (1991) 1.44
Growth inhibition and morphological changes caused by lipophilic acids in mammalian cells. Proc Natl Acad Sci U S A (1973) 1.41
F-actin aggregates in transformed cells. J Cell Biol (1981) 1.40
Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. Environ Health Perspect (1989) 1.37
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1971) 1.34
Carbohydrate catabolism and the enhancement of uptake of galactose in hamster cells transformed by polyoma virus. Proc Natl Acad Sci U S A (1973) 1.34
Studies on the mechanism of action of nerve growth factor. Proc Natl Acad Sci U S A (1972) 1.32
Treatment of intra-abdominal and abdominal wall desmoid tumors with drugs that affect the metabolism of cyclic 3',5'-adenosine monophosphate. Ann Surg (1975) 1.32
Purification and identification of the fruiting-inducing substances in Coprinus macrorhizus. J Bacteriol (1973) 1.32
A mutant of 3T3 cells with cyclic AMP metabolism sensitive to temperature change. Proc Natl Acad Sci U S A (1973) 1.24
Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism. Mol Biol Cell (2000) 1.22
Cyclic AMP modulates microvillus formation and agglutinability in transformed and normal mouse fibroblasts. Proc Natl Acad Sci U S A (1975) 1.22
Effects of red light on the growth of intact wheat and barley coleoptiles. Plant Physiol (1975) 1.21
Conditions leading to enhanced response to glucagon, epinephrine, or prostaglandins by adenylate cyclase of normal and malignant cultured cells. Proc Natl Acad Sci U S A (1971) 1.20
Immunofluorescent localization of cyclic nucleotide-dependent protein kinases on the mitotic apparatus of cultured cells. J Cell Biol (1980) 1.19
Neoplastic transformation in vitro of a clone of adult liver epithelial cells into differentiated hepatoma-like cells under conditions of nutritional stress. Proc Natl Acad Sci U S A (1972) 1.16
Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells. Proc Natl Acad Sci U S A (1974) 1.15
Interaction of polymorphonuclear neutrophils with Escherichia coli. Effect of enterotoxin on phagocytosis, killing, chemotaxis, and cyclic AMP. J Clin Invest (1978) 1.13
The ultrastructure of neuroblastoma glioma somatic cell hybrids. Expression of neuronal characteristics stimulated by dibutyryl adenosine 3',5' cyclic monophosphate. J Cell Biol (1974) 1.12
Control of cell volume in the J774 macrophage by microtubule disassembly and cyclic AMP. J Cell Biol (1981) 1.09
Transformation of chick-embryo fibroblasts by wild-type and temperature-sensitive Rous sarcoma virus alters adenylate cyclase activity. Proc Natl Acad Sci U S A (1973) 1.08
Measurement of the ability of cells to infiltrate normal tissues in vitro. Br J Cancer (1974) 1.06
Deposition of fibronectin in the course of reverse transformation of Chinese hamster ovary cells by cyclic AMP. Proc Natl Acad Sci U S A (1980) 1.06
Adenosine 3',5'-cyclic monophosphate-deficient mutants of Vibrio cholerae. J Bacteriol (1974) 1.06
Evidence for pleiotropic changes in lines of Chinese hamster ovary cells resistant to concanavalin A and phytohemagglutinin-P. J Cell Biol (1973) 1.06
Growth-and density-dependent inhibition of deoxyglucose transport in Balb 3T3 cells and its absence in cells transformed by murine sarcoma virus. Proc Natl Acad Sci U S A (1973) 1.05
The content and metabolism of cyclic adenosine 3', 5'-monophosphate and cyclic guanosine 3', 5'-monophosphate in adenocarcinoma of the human colon. J Clin Invest (1976) 1.05
Morphological alterations and ganglioside sialyltransferase activity induced by small fatty acids in HeLa cells. J Cell Biol (1975) 1.04
Growth of normal and transformed rat embryo fibroblasts: effects of glycolipids from Salmonella minnesota R mutants. J Cell Biol (1973) 1.02
Membrane changes during cartilage maturation. Increase in 5'-nucleotidase and decrease in adenosine inhibition of adenylate cyclase. J Cell Biol (1977) 1.02
Dibutyryl cyclic adenosine 3'5' monophosphate, sugar transport, and regulatory control of cell division in normal and transformed cells. J Cell Biol (1973) 1.00
Dibutyryl cAMP-inducible alkaline phosphatase in animal cell plasma membranes: fluorescence detection of mutant clones on polyester cloth. Proc Natl Acad Sci U S A (1983) 0.99
Cyclic AMP and cyclic GMP concentrations in serum- and density-restricted fibroblast cultures. Proc Natl Acad Sci U S A (1975) 0.98
Cytoskeletal involvement in cAMP-induced sensitization of chromatin to nuclease digestion in transformed Chinese hamster ovary K1 cells. Proc Natl Acad Sci U S A (1984) 0.98
Alteration of nucleoside transport of Chinese hamster cells by dibutyryl adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1972) 0.96
Adenosine 3': 5'-cyclic monophosphate in young and senescent human fibroblasts during growth and stationary phase in vitro. Effects of prostaglandine E1 and of adrenaline. Biochem J (1974) 0.94
The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells. Proc Natl Acad Sci U S A (1990) 0.94
Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin. Infect Immun (1977) 0.94
Involvement of vimentin in the reverse transformation reaction. Proc Natl Acad Sci U S A (1989) 0.93
Cell to substratum adhesion-promoting activity released by normal and virus-transformed cells in culture. J Cell Biol (1976) 0.93
The effect of light on fruiting body formation and adenosine 3':5'-cyclic monophosphate metabolism in Coprinus macrorhizus. Proc Natl Acad Sci U S A (1974) 0.92
Microtubule assembly in cultivated Greene melanoma cells is stimulated by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin. J Cell Biol (1976) 0.91
Specificity of the cAMP-induced gene exposure reaction in CHO cells. Proc Natl Acad Sci U S A (1988) 0.91
Analysis of chemotaxis in white blood cells. Biophys J (1971) 0.90
Localization of the catalytic subunit of cyclic AMP-dependent. Protein kinase in cultured cells using a specific antibody. J Cell Biol (1982) 0.90
Cyclic AMP mediates the concanavalin A agglutinability of mouse fibroblasts. J Cell Biol (1974) 0.89
Relationship between dibutyryl cyclic AMP and microtubule organization in contracting heart muscle cells. Proc Natl Acad Sci U S A (1978) 0.88
Concomitant effects of insulin on surface membrane conformation and polysome profiles of serum-starved BALB-C 3T3 fibroblasts. J Cell Biol (1974) 0.88
Effects of cyclic AMP and Sephadex fractions of chick embryo extract on cloned retinal pigmented epithelium in tissue culture. J Cell Biol (1974) 0.88
Transformation of trophic Hartmannella culbertsoni into viable cysts of cyclic 3',5'-adenosine monophosphate. J Cell Biol (1972) 0.87
Antagonism by dibutyryl adenosine cyclic 3',5'-monophosphate and testololactone of concanavalin A capping. J Cell Biol (1975) 0.86
Calcium and microtubule dependence for increased ornithine decarboxylase activity stimulated by beta-adrenergic agonists, dibutyryl cyclic AMP, or serum in a rat astrocytoma cell line. Proc Natl Acad Sci U S A (1980) 0.86
Cyclic AMP-induced morphological transformation of cells infected by temperature-sensitive mouse sarcoma virus. Expression of transformation-associated markers. J Cell Biol (1977) 0.85
Cholera toxin treatment stimulates tumorigenicity of Rous sarcoma virus-transformed cells. Mol Cell Biol (1984) 0.85
Desensitization of enucleated cells to hormones and role of cytoskeleton in control of normal hormonal response. Proc Natl Acad Sci U S A (1980) 0.85
Neoplastic transformation of cultured mammalian cells by estrogens and estrogenlike chemicals. Environ Health Perspect (1997) 0.84
Affinity purification of cardiac adenylate cyclase: dependence on prior hydrophobic resolution. Proc Natl Acad Sci U S A (1978) 0.83
Response of Dictyostelium plasma membranes to adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1973) 0.83
Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model. J Cell Biol (1983) 0.82
Role of tumor invasiveness, the extracellular matrix, and chromatin sequestration in the susceptibility of uveal melanoma to herpes simplex virus type 1. Exp Eye Res (2007) 0.82
Colchicine binding to bovine anterior pituitary slices and inhibition of growth-hormone release. Biochem J (1975) 0.81
Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period. Acta Neuropathol (1980) 0.81
An "external" RNA removable from mammalian cells by mild proteolysis. Proc Natl Acad Sci U S A (1974) 0.80
Phosphorylation of high-molecular-weight membrane protein species in Chinese-hamster ovary cells in culture: effect of 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate plus testosterone. Biochem J (1973) 0.80
Antagonism by dibutyryl adenosine cyclic 3',5'-monophosphate and testosterone of cell rounding reactions. J Cell Biol (1973) 0.78
Comparative studies on the carbohydrate-containing membrane components of normal and adenosine 3':5'-cyclic monophosphate-treated Chinese hamster ovary cells. Biochem J (1973) 0.78
Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone. Biochem J (1998) 0.78
Bacterial expression of Chinese hamster regulatory type-I and catalytic subunits of cyclic AMP-dependent protein kinase and mutational analysis of the type-I regulatory subunit. Biochem J (1994) 0.78
Effect of dibutyryl adenosine cyclic 3',5'-monophosphate and testololactone on concanavalin A binding and cell killing. J Cell Biol (1974) 0.78
Promotion of monolayer formation in cultured whole pancreatic islets by 3-isobutyl-1-methylxanthine. Proc Natl Acad Sci U S A (1978) 0.77
Interplay of cyclic AMP and microtubules in modulating the initiation of DNA synthesis in 3T3 cells. J Cell Biol (1983) 0.77
cAMP induces co-translational modification of proteins in IPC-81 cells. Biochem J (1999) 0.77
Patterns of cyclic nucleotides in normal and leukaemic human leucocytes. Br J Cancer (1980) 0.77
Surface morphology of normal and neoplastic rat cells. Am J Pathol (1977) 0.77
Elevation of cyclic AMP activates an actin-dependent contraction in teleost retinal rods. J Cell Biol (1982) 0.76
Morphological evidence for cyclic AMP-induced reverse transformation in vole cells infected with avian sarcoma virus. Mol Cell Biol (1982) 0.75
Adenovirus type 12 transformation involves loss of beta-adrenergic receptors and isoproterenol responsiveness. Mol Cell Biol (1982) 0.75
An analysis of lectin-initiated cell agglutination in a series of CHO subclones which respond morphologically to growth in dibutyryl cyclic AMP. J Cell Biol (1976) 0.75
Differential morphological reaction of experimental CNS tumour clones in vitro to dibutyryl cyclic AMP or serum-free medium, resp. Acta Neuropathol (1975) 0.75
Dibutyryladenosine 3':5'-cyclic monophosphate-mediated changes in rat cells involve macromolecular alterations in vinblastine-precipitable proteins. Biochem J (1978) 0.75
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Mammalian cell growth proteins. I. Growth stimulation of fetuin. Proc Natl Acad Sci U S A (1968) 2.40
Complementation analysis on virus-fused Chinese hamster cells with nutritional markers. Science (1969) 2.12
An analysis of the mechanism of neoplastic cell transformation by polyoma virus, hydrocarbons, and x-irradiation. Curr Top Dev Biol (1967) 1.64
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Further changes in differentiation state accompanying the conversion of Chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones. Proc Natl Acad Sci U S A (1971) 3.23
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Phenotypic expression time of mutagen-induced 6-thioguanine resistance in Chinese hamster ovary cells (CHO/HGPRT system). Mutat Res (1979) 0.90
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Steady-state concentrations of glucose-6-phosphate, 6-phosphogluconate, and reduced nicotinamide adenine dinucleotide phosphate in strains of Escherichia coli sensitive and resistant to catabolite repression. J Bacteriol (1969) 0.88
The role of butyrate in the reverse transformation reaction in mammalian cells. J Cell Physiol (1978) 0.88
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