Published in Immunology on March 01, 1992
The role of complement component C3b and its receptors in sperm-oocyte interaction. Proc Natl Acad Sci U S A (1993) 1.05
Differential expression of complement regulatory proteins decay-accelerating factor (CD55), membrane cofactor protein (CD46) and CD59 during human spermatogenesis. Immunology (1994) 1.02
Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59. J Clin Invest (1995) 0.98
Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line. Immunology (1994) 0.92
Expression of CD59, a complement regulator protein and a second ligand of the CD2 molecule, and CD46 in normal and neoplastic colorectal epithelium. Br J Cancer (1993) 0.90
Characterization of a glycosyl-phosphatidylinositol anchor-deficient subline of Raji cells. An analysis of the functional importance of complement inhibitors on the Raji cell line. Immunology (1995) 0.81
The lipopolysaccharide co-receptor CD14 is present and functional in seminal plasma and expressed on spermatozoa. Immunology (2001) 0.77
The complement regulatory proteins CD55 (decay accelerating factor) and CD59 are expressed on the inner acrosomal membrane of human spermatozoa as well as CD46 (membrane cofactor protein). Immunology (2006) 0.76
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
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CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. J Exp Med (1989) 4.19
Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology (1990) 2.77
The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol (1990) 2.48
Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria. J Clin Invest (1989) 2.01
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SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest (1988) 1.90
Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci U S A (1989) 1.85
Monoclonal antibodies capable of causing hemolysis of neuraminidase-treated human erythrocytes by homologous complement. J Immunol (1989) 1.70
Cobra venom factor: improved method for purification and biochemical characterization. J Immunol Methods (1984) 1.65
Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems. EMBO J (1989) 1.52
The human cell-surface glycoproteins HuLy-m5, membrane co-factor protein (MCP) of the complement system, and trophoblast leucocyte-common (TLX) antigen, are CD46. Immunology (1990) 1.45
The preparation and characterization of monoclonal antibodies to human complement component C8 and their use in purification of C8 and C8 subunits. Biochem J (1988) 1.41
The micro-sperm immobilization test: the use of only motile spermatozoa and studies of complement. Clin Exp Immunol (1978) 1.33
The detection of antibodies to spermatozoa and to blood group antigens in cervical mucus. J Reprod Fertil (1967) 1.33
The presence of complement in human cervical mucus and its possible relevance to infertility in women with complement-dependent sperm-immobilizing antibodies. Fertil Steril (1979) 1.32
Immune infertility and new approaches to treatment. Fertil Steril (1978) 1.25
Isolation and characterization of a membrane-attack-complex-inhibiting protein present in human serum and other biological fluids. Biochem J (1990) 1.22
Molecular cloning and characterization of MACIF, an inhibitor of membrane channel formation of complement. J Biochem (1989) 1.20
Interrelation between high levels of sperm antibodies, reduced penetration of cervical mucus by spermatozoa, and sterility in men. Acta Obstet Gynecol Scand (1968) 1.19
Expression of HRF20, a regulatory molecule of complement activation, on peripheral blood mononuclear cells. Immunology (1990) 1.17
Human seminal clusterin (SP-40,40). Isolation and characterization. J Clin Invest (1990) 1.12
Human seminal plasma inhibition of complement. J Lab Clin Med (1980) 1.11
Reversible cell damage by T-cell perforins. Calcium influx and propidium iodide uptake into K562 cells in the absence of lysis. Biochem J (1990) 1.05
Trophoblast/leukocyte-common antigen is expressed by human testicular germ cells and appears on the surface of acrosome-reacted sperm. Biol Reprod (1989) 1.04
Prognosis of fertility of men with sperm agglutinins in the serum. Fertil Steril (1974) 1.01
A new enzymatic method to obtain high-yield F(ab)2 suitable for clinical use from mouse IgGl. Mol Immunol (1991) 0.99
Sperm/cervical-mucus crossed hostility testing and antisperm antibodies in the husband. Lancet (1977) 0.99
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A new microassay for spermocytotoxic antibody: comparison with passive hemagglutination assay for antisperm antibodies in couples with unexplained fertility. J Immunol (1981) 0.83
A radiomicroassay for cytotoxic antibody to human spermatozoa. Quantification by tritiated actinomycin d. Clin Exp Immunol (1977) 0.81
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Identification of antisperm antibodies on sperm of infertile men. Fertil Steril (1982) 0.81
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The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature (1993) 7.39
A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med (2015) 4.95
Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology (1990) 2.77
Microrheology, stress fluctuations, and active behavior of living cells. Phys Rev Lett (2003) 2.62
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med (1997) 2.61
GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron (1998) 2.34
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Immunoaffinity purification of human complement component C9 using monoclonal antibodies. J Immunol Methods (1983) 2.11
Electrocardiographs in general practice. BMJ (1989) 2.07
Prospective evaluation of stapled haemorrhoidopexy versus transanal haemorrhoidal dearterialisation for stage II and III haemorrhoids: three-year outcomes. Tech Coloproctol (2011) 1.92
Recovery of human neutrophils from complement attack: removal of the membrane attack complex by endocytosis and exocytosis. J Immunol (1987) 1.92
Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. Biochemistry (1994) 1.84
Identification of a new glucosinolate-rich cell type in Arabidopsis flower stalk. Plant Physiol (2000) 1.76
The management of Chlamydia trachomatis: combined community and hospital study. Sex Transm Infect (2000) 1.72
The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of alpha2delta subunits is key to trafficking voltage-gated Ca2+ channels. Proc Natl Acad Sci U S A (2005) 1.65
Prospective randomized trial to assess caloric and protein needs of critically Ill, anuric, ventilated patients requiring continuous renal replacement therapy. Nutrition (2003) 1.65
Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria. Blood (2001) 1.65
Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59. J Exp Med (1997) 1.65
Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir. Nat Struct Biol (1995) 1.62
A survey of basic resuscitation knowledge among resident paediatricians. Arch Dis Child (1993) 1.61
The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement. Am J Pathol (1993) 1.59
Monoclonal antibodies demonstrate protection of polymorphonuclear leukocytes against complement attack. Nature (1985) 1.59
Immunopathology of secondary-progressive multiple sclerosis. Ann Neurol (2001) 1.58
Peptide-specific antibodies as probes of the orientation of the glucose transporter in the human erythrocyte membrane. J Biol Chem (1987) 1.57
Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology (2000) 1.56
Myositis, polyserositis with a large pericardial effusion and constrictive pericarditis as manifestations of chronic graft-versus-host disease after non-myeloablative peripheral stem cell transplantation and subsequent donor lymphocyte infusion. Bone Marrow Transplant (2001) 1.54
Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement. Nature (1989) 1.49
The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium. Biochem J (1985) 1.49
Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14. J Exp Med (2000) 1.48
Is provisional stenting the effective option? The WIDEST study (Wiktor stent in de novo stenosis). Widest Trial Investigators' Group. Heart (2000) 1.48
Evaluation of the sporicidal activity of different chemical disinfectants used in hospitals against Clostridium difficile. J Hosp Infect (2011) 1.47
Detection of trisomy 18 and Y-derived sequences in fetal nucleated cells obtained by transcervical flushing. Lancet (1993) 1.46
Evidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channels. Biophys J (2001) 1.45
Current oxygenation practice in ventilated patients-an observational cohort study. Anaesth Intensive Care (2013) 1.45
Role and regulation of pig CD59 and membrane cofactor protein/CD46 expressed on pig aortic endothelial cells. Transplantation (2000) 1.43
Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement. Biochem J (1992) 1.43
A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 2. Laboratory results. J Neurol Neurosurg Psychiatry (1987) 1.42
Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion. J Comp Neurol (1984) 1.42
Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain. EMBO J (1997) 1.42
The preparation and characterization of monoclonal antibodies to human complement component C8 and their use in purification of C8 and C8 subunits. Biochem J (1988) 1.41
Reproducibility of the measurement of submucous fibroid protrusion into the uterine cavity using three-dimensional saline contrast sonohysterography. Ultrasound Obstet Gynecol (2006) 1.41
Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am J Pathol (1997) 1.41
Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent. J Cell Biol (1995) 1.40
Upper airways resistance and snoring in anaesthetized dogs. Eur Respir J (1988) 1.38
Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines. J Immunol (1995) 1.35
Inhibition of complement-induced [14C]sucrose release by intracellular and extracellular monoclonal antibodies to C9: evidence that C9 is a transmembrane protein. Biochem Biophys Res Commun (1984) 1.33
Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease. Exp Neurol (1999) 1.32
Streptococcal inhibitor of complement (SIC) inhibits the membrane attack complex by preventing uptake of C567 onto cell membranes. Immunology (2001) 1.31
Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis. J Immunol (1994) 1.30
Tissue distribution of complement regulatory membrane proteins in rats. Immunology (1994) 1.29
The glycosylation of the complement regulatory protein, human erythrocyte CD59. J Biol Chem (1997) 1.28
Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients. Pain (2011) 1.28
Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis. Am J Pathol (2000) 1.27
Dominant-negative synthesis suppression of voltage-gated calcium channel Cav2.2 induced by truncated constructs. J Neurosci (2001) 1.27
Human factor H-related protein 5 (FHR-5). A new complement-associated protein. J Biol Chem (2000) 1.26
Posterior sternoclavicular dislocations--a diagnosis easily missed. Ann R Coll Surg Engl (1999) 1.26
Intracellular Ca2+ and cell injury: a paradoxical role of Ca2+ in complement membrane attack. Cell Calcium (1986) 1.25
Ocular abnormalities in Alagille syndrome. Ophthalmology (1999) 1.25
Time course of complement activation and inhibitor expression after ischemic injury of rat myocardium. Am J Pathol (1994) 1.24
The nucleotide sequence of Staphylococcus aureus plasmid pT48 conferring inducible macrolide-lincosamide-streptogramin B resistance and comparison with similar plasmids expressing constitutive resistance. J Gen Microbiol (1988) 1.22
Functionally active complement proteins C6 and C7 detected in C6- and C7-deficient individuals. Clin Exp Immunol (1991) 1.22
The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis. J Immunol (1998) 1.22
Soluble complement receptor 1 (sCR1) protects against experimental autoimmune myasthenia gravis. J Neuroimmunol (1996) 1.21
Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation. J Neuroimmunol (1989) 1.20
Characteristics of growth of a Pseudomonas species in culture media containing chlorhexidine. Biochem J (1968) 1.20
Human and rodent decay-accelerating factors (CD55) are not species restricted in their complement-inhibiting activities. Immunology (2000) 1.19
A pilot study of urokinase therapy in cerebral infarction. Stroke (1976) 1.19
Failure of thrombolysis by streptokinase: detection with a simple electrocardiographic method. Heart (2000) 1.19
A dislocated mobile bearing from a unicondylar knee replacement--a complication not to be missed. Ann R Coll Surg Engl (2010) 1.17
The human and mouse GATA-6 genes utilize two promoters and two initiation codons. J Biol Chem (1999) 1.17
Comparison of the action of vantocil, cetrimide and chlorhexidine on Escherichia coli and its spheroplasts and the protoplasts of gram positive bacteria. J Appl Bacteriol (1968) 1.17
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Complement regulation at the molecular level: the structure of decay-accelerating factor. Proc Natl Acad Sci U S A (2004) 1.17
Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma. Leukemia (2007) 1.17
Genetic analysis of the epidermal differentiation complex (EDC) on human chromosome 1q21: chromosomal orientation, new markers, and a 6-Mb YAC contig. Genomics (1996) 1.17
Influence of lung stretch receptors on the cough reflex in rabbits. Respiration (1984) 1.17
Complement in multiple sclerosis: its role in disease and potential as a biomarker. Clin Exp Immunol (2008) 1.17
Accidental vulval injuries in childhood. BMJ (1989) 1.17
Characterization of the membrane attack complex inhibitory protein CD59 antigen on human amniotic cells and in amniotic fluid. Immunology (1992) 1.17
A phase II study investigating the re-induction of endocrine sensitivity following chemotherapy in androgen-independent prostate cancer. Br J Cancer (2008) 1.15
Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J Immunol (1995) 1.14
Endoscopic reconstruction of the anterior cruciate ligament with an ipsilateral patellar tendon autograft. A prospective longitudinal five-year study. J Bone Joint Surg Br (2000) 1.13
The role of complement in the pathogenesis of experimental allergic encephalomyelitis. Brain (1989) 1.13
Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies. J Neurol Sci (1989) 1.13
A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial. Curr Med Res Opin (2009) 1.13
Stimulation of human rheumatoid synovial cells by non-lethal complement membrane attack. Immunology (1990) 1.12
The practical management of claudication. BMJ (2000) 1.12
Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition. Blood (1999) 1.10
A pericentric inversion of chromosome six in a patient with Peutz-Jeghers' syndrome and the use of FISH to localise the breakpoints on a genetic map. Hum Genet (1996) 1.10
Cellular stress induces a redistribution of the glucose transporter. FASEB J (1990) 1.10
Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement. J Clin Invest (1995) 1.10
Efficient generation of monoclonal antibodies against surface-expressed proteins by hyperexpression in rodent cells. J Immunol Methods (1999) 1.09
Coronary care in a general practitioner hospital. Br Med J (Clin Res Ed) (1982) 1.09
Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. Arthritis Rheum (2004) 1.09
Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clin Exp Immunol (2009) 1.09
Immunoradiometric assay for human complement component C9 utilising monoclonal antibodies. Clin Chim Acta (1983) 1.08