Published in Immunogenetics on January 01, 1992
Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection. Springer Semin Immunopathol (2006) 2.09
Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene. J Exp Med (1994) 1.53
Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes. Nucleic Acids Res (1993) 1.21
Interferon regulatory factor expression in human breast cancer. Ann Surg (2001) 0.98
Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes. Gene (2011) 0.96
A novel interferon regulatory factor (IRF), IRF-10, has a unique role in immune defense and is induced by the v-Rel oncoprotein. Mol Cell Biol (2002) 0.93
Transcriptional regulation of HLA-A and -B: differential binding of members of the Rel and IRF families of transcription factors. Proc Natl Acad Sci U S A (1993) 0.89
What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules? Immunol Res (2010) 0.86
The SCHOOL of nature: IV. Learning from viruses. Self Nonself (2010) 0.77
Functional polymorphisms of interferon-gamma affect pneumonia-induced sepsis. PLoS One (2014) 0.76
IRF1 Downregulation by Ras/MEK Is Independent of Translational Control of IRF1 mRNA. PLoS One (2016) 0.75
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature (2001) 25.15
A physical map of the DNA regions flanking the rabbit beta-globin gene. Cell (1977) 12.96
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell (1997) 12.68
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science (1995) 11.38
Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature (1998) 11.08
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell (2001) 9.33
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (2000) 8.56
Localization of DNA sequences necessary for transcription of the rabbit beta-globin gene in vitro. Cell (1981) 8.48
DNA methylation in the human gamma delta beta-globin locus in erythroid and nonerythroid tissues. Cell (1980) 8.41
Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science (1990) 7.33
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature (1996) 7.27
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity (2000) 6.97
CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol (1998) 6.83
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell (1998) 6.79
DNA methylation and the regulation of globin gene expression. Cell (1983) 6.49
The rabbit beta-globin gene contains a large large insert in the coding sequence. Cell (1977) 6.45
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med (2000) 6.32
A method for the recovery of DNA from agarose gels. Nucleic Acids Res (1978) 6.24
MspI, an isoschizomer of hpaII which cleaves both unmethylated and methylated hpaII sites. Nucleic Acids Res (1978) 6.01
Isolation of beta-globin-related genes from a human cosmid library. Gene (1981) 5.97
Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow. J Exp Med (2001) 5.97
The construction of cosmid libraries which can be used to transform eukaryotic cells. Nucleic Acids Res (1982) 5.66
ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature (2001) 5.32
Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance. Cell (1978) 5.30
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature (1997) 5.29
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science (1997) 5.16
Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices. Nat Biotechnol (1999) 5.13
DNA sequences necessary for transcription of the rabbit beta-globin gene in vivo. Nature (1982) 4.97
DNA methylation at a CCGG sequence in the large intron of the rabbit beta-globin gene: tissue-specific variations. Nucleic Acids Res (1978) 4.77
The sequence GGCmCGG is resistant to MspI cleavage. Nucleic Acids Res (1983) 4.75
Essential role of phosphoinositide metabolism in synaptic vesicle recycling. Cell (1999) 4.70
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron (1999) 4.51
Mice deficient for the CD40 ligand. Immunity (1994) 4.45
Defective T cell differentiation in the absence of Jnk1. Science (1998) 4.40
Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse. Nature (1984) 4.22
Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med (1997) 4.06
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice. Immunity (1997) 3.99
The structure of a mutant H-2 gene suggests that the generation of polymorphism in H-2 genes may occur by gene conversion-like events. Nature (1983) 3.99
The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens. EMBO J (1983) 3.95
Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns. Nature (1978) 3.86
Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells. Nat Med (2001) 3.74
Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. Immunity (1998) 3.70
Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease. Infect Immun (1994) 3.59
Beta + thalassemia: aberrant splicing results from a single point mutation in an intron. Cell (1981) 3.51
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Borrelia burgdorferi genes selectively expressed in the infected host. Proc Natl Acad Sci U S A (1995) 3.42
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell (1995) 3.34
Turnover of carbon isotopes in tail hair and breath CO2 of horses fed an isotopically varied diet. Oecologia (2004) 3.14
Sequence requirements for the transcription of the rabbit beta-globin gene in vivo: the -80 region. Nucleic Acids Res (1982) 3.11
Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature (1995) 3.07
Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice. Infect Immun (1992) 3.04
Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice. Proc Natl Acad Sci U S A (1992) 2.99
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature (1996) 2.98
Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J (1999) 2.96
Beta-globin gene inactivation by DNA translocation in gamma beta-thalassaemia. Nature (1984) 2.83
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J Biol Chem (1998) 2.75
Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis. J Infect Dis (1994) 2.72
Structure and expression of a cloned beta o thalassaemic globin gene. Nucleic Acids Res (1981) 2.71
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol (1997) 2.71
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci U S A (1996) 2.70
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. EMBO J (1999) 2.70
gamma-beta-Thalassaemia studies showing that deletion of the gamma- and delta-genes influences beta-globin gene expression in man. Nature (1980) 2.68
Molecular mapping of Osp-A mediated immunity against Borrelia burgdorferi, the agent of Lyme disease. J Immunol (1991) 2.61
Domain interactions of H-2 class I antigens alter cytotoxic T-cell recognition sites. Nature (1984) 2.60
Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med (1998) 2.55
Borrelia burgdorferi strain 25015: characterization of outer surface protein A and vaccination against infection. J Immunol (1992) 2.49
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. Genes Dev (2001) 2.48
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc Natl Acad Sci U S A (1999) 2.43
Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon. Cell (1983) 2.42
Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice. Infect Immun (1994) 2.42
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J Exp Med (1994) 2.42
CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J Exp Med (1996) 2.42
Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway. EMBO J (1998) 2.41
Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity. Immunity (1997) 2.38
Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. Science (1996) 2.36
The DNA sequence of the 5' flanking region of the human beta-globin gene: evolutionary conservation and polymorphic differences. Nucleic Acids Res (1982) 2.36
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell (1988) 2.36
JNK is required for effector T-cell function but not for T-cell activation. Nature (2000) 2.33
The role of Fas in autoimmune diabetes. Cell (1997) 2.30
Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression. Immunity (1996) 2.28
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression. J Immunol (2000) 2.23
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci U S A (1997) 2.21
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. J Exp Med (1996) 2.21
Cell fate decision: T-helper 1 and 2 subsets in immune responses. Arthritis Res (2000) 2.21
Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH). Nucleic Acids Res (1980) 2.20
The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells. Cell (1993) 2.19
A potential donor gene for the bm1 gene conversion event in the C57BL mouse. Nature (1984) 2.18
Regulated expression of the human beta-globin gene family in murine erythroleukaemia cells. Nature (1983) 2.16
Defective antigen processing in GILT-free mice. Science (2001) 2.16
Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level. Immunity (2001) 2.15
A nonpolymorphic class I gene in the murine major histocompatibility complex. Cell (1984) 2.12
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat Med (2000) 2.11
Nonspecific proliferative responses of murine lymphocytes to Borrelia burgdorferi antigens. J Infect Dis (1992) 2.11
Response to local inflammation of IL-1 beta-converting enzyme- deficient mice. J Immunol (1997) 2.10
Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell (1996) 2.09
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J (1994) 2.08
A novel MHC class II epitope expressed in thymic medulla but not cortex. Nature (1989) 2.06
Mechanisms of programmed cell death in the developing brain. Trends Neurosci (2000) 2.05
Structure of the human fetal globin gene locus. Nature (1979) 2.02