J J BURNS

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material. J Pharmacol Exp Ther 1953 3.60
2 The fate of pentobarbital in man and dog and a method for its estimation in biological material. J Pharmacol Exp Ther 1953 2.38
3 A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther 1957 2.20
4 Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs. J Pharmacol Exp Ther 1960 2.04
5 The metabolic fate of phenylbutazone (butazolidin) in man. J Pharmacol Exp Ther 1955 1.76
6 Ascorbic acid synthesis in normal and drug-treated rats, studied with L-ascorbic-1-C14 acid. J Biol Chem 1954 1.61
7 DRUG INTERACTIONS IN MAN. I. LOWERING EFFECT OF PHENOBARBITAL ON PLASMA LEVELS OF BISHYDROXYCOUMARIN (DICUMAROL) AND DIPHENYLHYDANTOIN (DILANTIN). Clin Pharmacol Ther 1965 1.55
8 The synthesis of l-ascorbic acid by the albino rat. J Biol Chem 1950 1.53
9 Metabolism of drugs in subjects with Laennec's cirrhosis. Med Exp Int J Exp Med 1959 1.38
10 Stimulatory effect of foreign compounds on ascorbic acid biosynthesis and on drug-metabolizing enzymes. Nature 1959 1.26
11 Missing step in guinea pigs required for the biosynthesis of L-ascorbic acid. Science 1956 1.22
12 Observations on the antirheumatic and physiologic effects of phenylbutazone (butazolidin) and some comparisons with cortisone. Am J Med 1954 1.22
13 Stimulatory effect of barbital on urinary excretion of L-ascorbic acid and nonconjugated D-glucuronic acid. J Biol Chem 1957 1.20
14 Results of a clinical trial of G-28315, a sulfoxide analog of phenylbutazone, as a uricosuric agent in gouty subjects. Arthritis Rheum 1958 1.18
15 Metabolism of ascorbic acid and related uronic acids, aldonic acids, and pentoses. Ann N Y Acad Sci 1961 1.15
16 Metabolic interactions between L-ascorbic acid and drugs. Ann N Y Acad Sci 1961 1.12
17 The metabolism of 1-C14-L-ascorbic acid in guinea pigs. J Biol Chem 1951 1.10
18 A study of the inverse relationship between pKa and rate of renal excretion of phenylbutazone analogs in man and dog. Am J Med 1960 1.08
19 Biochemical pharmacological considerations of phenylbutazone and its analogues. Ann N Y Acad Sci 1960 1.08
20 The biotransformation of ethyl biscoumacetate (tromexan) in man, rabbit and dog. J Pharmacol Exp Ther 1953 1.08
21 Phenylbutazone metabolites: antirheumatic, sodium-retaining and uricosuric effects in man. J Pharmacol Exp Ther 1958 1.07
22 The synthesis of L-ascorbic acid in the rat from D-glucuronolactone and L-gulonolactone. J Biol Chem 1956 1.07
23 Metabolism of L-ascorbic acid-1-C14 in man. J Biol Chem 1958 1.06
24 Studies on the glucuronic acid pathway of glucose metabolism. J Biol Chem 1959 1.06
25 Missing step in man, monkey and guinea pig required for the biosynthesis of L-ascorbic acid. Nature 1957 1.05
26 Zoxazolamine: physiological disposition, uricosuric properties. Am J Med 1958 1.04
27 Observations on the drug-induced synthesis of D-glucuronic, L-gulonic and L-ascorbic acids in rats. J Pharmacol Exp Ther 1960 1.03
28 STIMULATORY EFFECT OF PHENOBARBITAL ON THE METABOLISM OF DIPHENYLHYDANTOIN. J Pharmacol Exp Ther 1963 1.02
29 The physiological disposition and fate of meperidine (demerol) in man and a method for its estimation in plasma. J Pharmacol Exp Ther 1955 1.01
30 Intravenous anesthetics; new concepts. I. Experimental aspects. Curr Res Anesth Analg 1952 0.98
31 Further observations on the metabolism of L-ascorbic acid in guinea pigs. J Biol Chem 1956 0.97
32 Metabolism of L-gulonolactone in rats via pentose formation. Biochim Biophys Acta 1957 0.97
33 Observations on G-25671, a phenylbutazone analogue (4-phenylthioethyl)-1,2-diphenyl 3,5-pyrazolidinedione). Proc Soc Exp Biol Med 1955 0.97
34 The appearance of procaine in the spinal fluid during peridural block in man. J Pharmacol Exp Ther 1953 0.96
35 APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES. Ann N Y Acad Sci 1965 0.95
36 Observations on vitamin C activity of D-ascorbic acid. Proc Soc Exp Biol Med 1959 0.95
37 Relationship between pKa and uricosuric activity in phenylbutazone analogues. Nature 1958 0.95
38 INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS. Adv Enzyme Regul 1963 0.94
39 Effect of a phenylbutazone analog (4-[phenylthioethyl]-1, 2-diphenyl 3, 5-pyrazolidinedione) on urate clearance and other discrete renal functions in gouty subjects; evaluation as uricosuric agent. J Clin Invest 1956 0.93
40 BLOCKADE OF SOME METABOLIC EFFECTS OF CATECHOLAMINES BY N-ISOPROPYL METHOXAMINE (B.W. 61-43). J Pharmacol Exp Ther 1964 0.92
41 The passage of thiopental into brain. J Pharmacol Exp Ther 1957 0.91
42 IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY. Am J Med 1964 0.91
43 Observations on the metabolic transformation and effects of phenylbutazone in subjects with hepatic disease. Am J Med Sci 1954 0.91
44 The passage of thiobarbiturates and their oxygen analogs into brain. J Pharmacol Exp Ther 1958 0.90
45 Conversion of myo-inositol to D-glucuronic acid and L-gulonic acid in the rat. Biochim Biophys Acta 1959 0.87
46 Metabolism of sulfinpyrazone (Anturane) and other thio analogues of phenylbutazone in man. J Pharmacol Exp Ther 1961 0.87
47 Metabolism of C14-labeled ascorbic, dehydroascorbic and diketoglulonic acids in guinea pigs. Arch Biochem Biophys 1959 0.87
48 The control of prothrombin activity with tromexan therapy. Am J Med 1953 0.85
49 The physiological disposition of ethyl biscoumacetate (tromexan) in man and a method for its estimation in biological material. J Pharmacol Exp Ther 1952 0.84
50 INHIBITION OF LIPID MOBILIZATION BY N-ISOPROPYL METHOXAMINE (B.W. 61-43). J Pharmacol Exp Ther 1964 0.83
51 Metabolism of L-ascorbic acid in rat kidney. J Biol Chem 1958 0.82
52 Metabolism of D-galactose to D-glucuronic acid, L-gulonic acid and L-ascorbic acid in normal and barbital-treated rats. Biochim Biophys Acta 1960 0.82
53 Further observations on the biosynthesis of L-ascorbic acid from D-glucose in the rat. J Biol Chem 1956 0.82
54 Studies on the incorporation of C14 administered as L-sorbose into L-ascorbic acid and D-glucose in rats. J Biol Chem 1955 0.81
55 Biosynthesis of L-ascorbic acid; basic defect in scurvy. Am J Med 1959 0.80
56 Studies of the mechanism of L-xylulose formation by kidney enzymes. J Biol Chem 1959 0.80
57 The metabolic fate of zoxazolamine (flexin) in man. J Pharmacol Exp Ther 1960 0.78
58 The transmission of meperidine across the human placenta. Am J Obstet Gynecol 1952 0.77
59 PHYSIOLOGICAL DISTRIBUTION AND METABOLIC INACTIVATION OF CHLORCYCLIZINE AND CYCLIZINE. J Pharmacol Exp Ther 1965 0.77
60 Formation of L-lyxonic and L-xylonic acids from L-ascorbic acid in rat kidney. J Biol Chem 1960 0.77
61 Physiological disposition and metabolic fate of chlorzoxazone (paraflex) in man. J Pharmacol Exp Ther 1960 0.77
62 Stimulatory effect of chlorcyclizine on barbiturate metabolism. J Pharmacol Exp Ther 1961 0.75
63 Formation of L-xylulose from L-gulonic acid in rat kidney. Biochim Biophys Acta 1959 0.75
64 Clinical application of studies of the physiologic disposition of thiopental. N Y State J Med 1956 0.75
65 Biochemical pharmacological considerations of zoxazolamine and chlorzoxazone metabolism. Ann N Y Acad Sci 1960 0.75
66 Water-soluble vitamins, Part I. (Ascorbic acid, nicotinic acid, vitamin B6, biotin, inositol). Annu Rev Biochem 1960 0.75
67 Physiological disposition of certain N-alkyl thiobarbiturates. Anesthesiology 1955 0.75
68 Effect of phenylbutazone (butazolidin) on experimentally induced ocular inflammation. AMA Arch Ophthalmol 1955 0.75
69 Metabolism of D-ascorbic acid-1-C14 in guinea pigs and rats. J Biol Chem 1958 0.75
70 A p-nitro analogue of phenylbutazone possessing potent antirheumatic, sodium retaining and uricosuric properties. J Pharmacol Exp Ther 1959 0.75
71 Observations on bound ascorbic acid in guinea pig liver. Proc Soc Exp Biol Med 1956 0.75
72 THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM. Semin Hematol 1964 0.75
73 Physiologic disposition and uricosuric effect of a keto analog of oxyphenbutazone (G-29701). Arthritis Rheum 1960 0.75
74 Sites of sensory blockade during segmental spinal and segmental peridural anesthesia in man. Anesthesiology 1953 0.75
75 LOWERING EFFECT OF NEOSTIGMINE ON PLASMA FREE FATTY ACIDS. Nature 1964 0.75
76 Observations on effect of 3-methylcholanthrene in scorbutic guinea pigs. Proc Soc Exp Biol Med 1961 0.75
77 Intravenous anesthesia; new concepts. II. Clinical aspects. Curr Res Anesth Analg 1952 0.75
78 Role of ascorbic acid in the formation and maintenance of dental structures. Ann N Y Acad Sci 1961 0.75