Published in J Biol Chem on September 30, 2003
Peripheral chemoreceptors: function and plasticity of the carotid body. Compr Physiol (2012) 2.30
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AMP-activated protein kinase mediates carotid body excitation by hypoxia. J Biol Chem (2006) 1.32
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Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body. J Physiol (2005) 0.91
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AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest (2007) 3.32
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The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J Clin Invest (2005) 2.40
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A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ Res (2006) 2.12
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Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels. J Physiol (2002) 1.80
Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes. Eur Heart J (2013) 1.69
Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? J Biol Chem (2005) 1.64
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell Metab (2009) 1.59
Sensing of lysophospholipids by TRPC5 calcium channel. J Biol Chem (2005) 1.54
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase. Proc Natl Acad Sci U S A (2010) 1.50
Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current. Am J Respir Crit Care Med (2012) 1.50
Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. Am J Respir Cell Mol Biol (2008) 1.48
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. Free Radic Biol Med (2009) 1.41
The production of amyloid beta peptide is a critical requirement for the viability of central neurons. J Neurosci (2003) 1.39
A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells. EMBO J (2006) 1.34
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Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain (2007) 1.31
A scaleable and defined system for generating neural stem cells from human embryonic stem cells. Stem Cells (2006) 1.26
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Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances. J Physiol (2006) 1.22
Physiological roles for amyloid beta peptides. J Physiol (2006) 1.16
Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proc Natl Acad Sci U S A (2011) 1.15
Amyloid beta peptide as a physiological modulator of neuronal 'A'-type K+ current. Neurobiol Aging (2005) 1.13
Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels. Respir Physiol Neurobiol (2010) 1.12
The calcium-sensing receptor beyond extracellular calcium homeostasis: conception, development, adult physiology, and disease. Annu Rev Physiol (2011) 1.12
Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species. J Biol Chem (2008) 1.12
Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence. Proc Natl Acad Sci U S A (2009) 1.10
The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis. Am J Physiol Endocrinol Metab (2010) 1.09
Hypoxia suppresses glutamate transport in astrocytes. J Neurosci (2007) 1.08
VennPlex--a novel Venn diagram program for comparing and visualizing datasets with differentially regulated datapoints. PLoS One (2013) 1.08
AMPK: regulating energy balance at the cellular and whole body levels. Physiology (Bethesda) (2014) 1.06
Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice. Biochem J (2012) 1.04
Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. FASEB J (2011) 1.04
Testosterone is a potent inhibitor of L-type Ca(2+) channels. Biochem Biophys Res Commun (2004) 1.04
Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons. Proc Natl Acad Sci U S A (2012) 1.03
alpha-Synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells. J Neurochem (2009) 1.02
Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia. J Neurochem (2002) 0.99
Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol (2008) 0.99
Hypoxic modulation of Ca2+ signaling in human venous endothelial cells. Multiple roles for reactive oxygen species. J Biol Chem (2005) 0.97
Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia. Biochem J (2010) 0.97
AMP-activated protein kinase couples mitochondrial inhibition by hypoxia to cell-specific Ca2+ signalling mechanisms in oxygen-sensing cells. Novartis Found Symp (2006) 0.97
Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels. FASEB J (2004) 0.96
Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing. Curr Opin Anaesthesiol (2011) 0.96
Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels. J Biol Chem (2009) 0.95
Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: physiological impact in acidosis and alkalosis. Am J Physiol Cell Physiol (2003) 0.95
An ion-channel modulator from the saliva of the brown ear tick has a highly modified Kunitz/BPTI structure. J Mol Biol (2009) 0.95
Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin. FASEB J (2013) 0.94
Selective expression in carotid body type I cells of a single splice variant of the large conductance calcium- and voltage-activated potassium channel confers regulation by AMP-activated protein kinase. J Biol Chem (2011) 0.94
Differential involvement of TNF alpha in hypoxic suppression of astrocyte glutamate transporters. Glia (2008) 0.94
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition. J Biol Chem (2012) 0.92
Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. Stroke (2002) 0.92
Ion channel regulation by AMPK: the route of hypoxia-response coupling in thecarotid body and pulmonary artery. Ann N Y Acad Sci (2009) 0.91
Molecular requirements for L-type Ca2+ channel blockade by testosterone. Cell Calcium (2006) 0.91
Carbon monoxide: an emerging regulator of ion channels. J Physiol (2011) 0.91
Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons. PLoS One (2013) 0.90
Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. PLoS One (2011) 0.90
Airway chemotransduction: from oxygen sensor to cellular effector. Am J Respir Crit Care Med (2002) 0.89
AMP-activated protein kinase and hypoxic pulmonary vasoconstriction. Eur J Pharmacol (2008) 0.89
Lack of contribution of mitochondrial electron transport to acute O(2) sensing in model airway chemoreceptors. Biochem Biophys Res Commun (2002) 0.89
Thiazide diuretics directly induce osteoblast differentiation and mineralized nodule formation by interacting with a sodium chloride co-transporter in bone. J Am Soc Nephrol (2007) 0.89
Hypoxia stimulates Ca2+ release from intracellular stores in astrocytes via cyclic ADP ribose-mediated activation of ryanodine receptors. Cell Calcium (2005) 0.89
Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis. J Biol Chem (2013) 0.88
Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. J Neurochem (2002) 0.87
A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BK Ca channels. Pflugers Arch (2008) 0.87
Modulation of hTREK-1 by carbon monoxide. Neuroreport (2008) 0.87
Development of a lung slice preparation for recording ion channel activity in alveolar epithelial type I cells. Respir Res (2005) 0.86
Gasotransmitter regulation of ion channels: a key step in O2 sensing by the carotid body. Physiology (Bethesda) (2014) 0.86
Hypoxia potentiates exocytosis and Ca2+ channels in PC12 cells via increased amyloid beta peptide formation and reactive oxygen species generation. J Physiol (2002) 0.86
Oxygen sensing by ion channels. Essays Biochem (2007) 0.86
Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression. Neurosignals (2012) 0.85
Modulation of Ca(2+) signalling in human vascular endothelial cells by hydrogen sulfide. Atherosclerosis (2009) 0.85
Modulation of 'A'-type K+ current by rodent and human forms of amyloid beta protein. Neuroreport (2008) 0.85
Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels. Pflugers Arch (2014) 0.85
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels. J Bioenerg Biomembr (2013) 0.84
Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. FASEB J (2008) 0.84
Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. Pflugers Arch (2011) 0.84
Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol (2011) 0.84
Cysteine residue 911 in C-terminal tail of human BK(Ca)α channel subunit is crucial for its activation by carbon monoxide. Pflugers Arch (2011) 0.83
Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts. J Mol Cell Cardiol (2009) 0.83
Peroxynitrite mediates disruption of Ca2+ homeostasis by carbon monoxide via Ca2+ ATPase degradation. Antioxid Redox Signal (2012) 0.83
Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways. Brain Res Mol Brain Res (2004) 0.82
H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death. Pflugers Arch (2007) 0.82
Vanilloid receptor type 1-immunoreactivity is expressed by intrinsic afferent neurones in the guinea-pig myenteric plexus. Neurosci Lett (2002) 0.82
Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. PLoS One (2013) 0.82
Nrf2 orchestrates fuel partitioning for cell proliferation. Cell Metab (2012) 0.81
Chronic hypoxia up-regulates expression of adenosine A1 receptors in DDT1-MF2 cells. Biochem Pharmacol (2004) 0.81
Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain. J Biol Chem (2005) 0.81
Novel regulatory aspects of the extracellular Ca2+-sensing receptor, CaR. Pflugers Arch (2009) 0.81
Key roles for AMP-activated protein kinase in the function of the carotid body? Adv Exp Med Biol (2008) 0.81
An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Exp Lung Res (2011) 0.81