Ernest Arenas

Author PubWeight™ 84.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci 2009 2.69
2 Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature 2008 2.24
3 Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A 2003 2.14
4 Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell 2009 1.84
5 A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development 2006 1.79
6 Derivation of mouse embryonic stem cells. Nat Protoc 2006 1.76
7 Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J Cell Sci 2007 1.65
8 Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 2006 1.58
9 Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest 2014 1.55
10 Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A 2007 1.46
11 Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proc Natl Acad Sci U S A 2010 1.31
12 Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest 2008 1.29
13 Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal 2006 1.26
14 Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci 2010 1.26
15 Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. J Neurochem 2005 1.24
16 GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. J Cell Sci 2004 1.24
17 Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J Biol Chem 2009 1.23
18 The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. Mol Biol Cell 2008 1.23
19 An efficient method for the derivation of mouse embryonic stem cells. Stem Cells 2005 1.20
20 Wnt5a regulates midbrain dopaminergic axon growth and guidance. PLoS One 2011 1.18
21 Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. Eur J Neurosci 2006 1.14
22 Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. PLoS One 2008 1.14
23 Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev 2003 1.13
24 The p75 neurotrophin receptor interacts with multiple MAGE proteins. J Biol Chem 2002 1.13
25 Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proc Natl Acad Sci U S A 2013 1.12
26 Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep 2008 1.12
27 Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol Cell Neurosci 2005 1.09
28 Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nat Chem Biol 2012 1.09
29 Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model. Development 2007 1.09
30 Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells. Stem Cells 2009 1.08
31 NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem Cells Dev 2005 1.08
32 Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia 2008 1.06
33 Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. PLoS One 2011 1.06
34 Differential expression of Wnts after spinal cord contusion injury in adult rats. PLoS One 2011 1.03
35 Vang-like protein 2 and Rac1 interact to regulate adherens junctions. J Cell Sci 2010 1.02
36 Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling. Biochem Biophys Res Commun 2009 1.02
37 Neural progenitors organize in small-world networks to promote cell proliferation. Proc Natl Acad Sci U S A 2013 1.01
38 Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency. PLoS One 2013 1.00
39 Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Mol Cell Neurosci 2004 0.99
40 Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway. BMC Cell Biol 2008 0.98
41 Function of Wnts in dopaminergic neuron development. Neurodegener Dis 2006 0.97
42 Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha. Circ Res 2008 0.97
43 Analysis of bioactive oxysterols in newborn mouse brain by LC/MS. J Lipid Res 2012 0.97
44 Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Exp Cell Res 2006 0.96
45 Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Mol Biosyst 2009 0.96
46 Control of neural stem cell adhesion and density by an electronic polymer surface switch. Langmuir 2008 0.94
47 Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons. Stem Cells Dev 2010 0.94
48 The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. Exp Cell Res 2008 0.93
49 Wnts are expressed in the spinal cord of adult mice and are differentially induced after injury. J Neurotrauma 2014 0.92
50 Delayed dopaminergic neuron differentiation in Lrp6 mutant mice. Dev Dyn 2010 0.90
51 Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease. Stem Cells 2005 0.90
52 SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem Cells 2012 0.90
53 The antimicrobial peptide rCRAMP is present in the central nervous system of the rat. J Neurochem 2005 0.89
54 Wnt2 regulates progenitor proliferation in the developing ventral midbrain. J Biol Chem 2009 0.87
55 Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation 2012 0.86
56 Alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres. Stem Cells 2008 0.86
57 Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Development 2003 0.86
58 Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs. Biochem Biophys Res Commun 2009 0.86
59 A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease. Stem Cells 2010 0.85
60 Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. Mol Cell Biol 2012 0.85
61 Genetic interaction between Lrp6 and Wnt5a during mouse development. Dev Dyn 2010 0.85
62 Region-specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons. Glia 2003 0.83
63 Increased Wnt levels in the neural tube impair the function of adherens junctions during neurulation. Mol Cell Neurosci 2005 0.82
64 Microarray analyses support a role for Nurr1 in resistance to oxidative stress and neuronal differentiation in neural stem cells. Stem Cells 2006 0.82
65 WNT unrelated activities in commercially available preparations of recombinant WNT3a. J Cell Biochem 2010 0.82
66 Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. J Neurosci Res 2012 0.81
67 Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity. Biochem Biophys Res Commun 2004 0.81
68 Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development 2013 0.81
69 Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. PLoS One 2012 0.81
70 BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors. J Neurochem 2006 0.80
71 Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. PLoS One 2011 0.80
72 Transplantable midbrain dopamine neurons: a moving target. Exp Neurol 2010 0.79
73 The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury. J Neurotrauma 2013 0.78
74 Stem-cell-based strategies for the treatment of Parkinson's disease. Neurodegener Dis 2007 0.77
75 Peptide-presenting two-dimensional protein matrix on supported lipid bilayers: an efficient platform for cell adhesion. Biointerphases 2007 0.77
76 BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors. J Neurobiol 2002 0.77
77 Neurturin is a neuritogenic but not a survival factor for developing and adult central noradrenergic neurons. J Neurochem 2002 0.76
78 Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. J Neurobiol 2002 0.75
79 Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule. Cell 2017 0.75