Published in Cell Stem Cell on October 02, 2009
Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest (2014) 1.55
Sterols and oxysterols in immune cell function. Nat Immunol (2013) 1.41
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J Biol Chem (2009) 1.23
Coordinated regulation of niche and stem cell precursors by hormonal signaling. PLoS Biol (2011) 1.13
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nat Chem Biol (2012) 1.09
Sterol regulation of metabolism, homeostasis, and development. Annu Rev Biochem (2011) 1.08
Analysis of bioactive oxysterols in newborn mouse brain by LC/MS. J Lipid Res (2012) 0.97
Lipid pathway alterations in Parkinson's disease primary visual cortex. PLoS One (2011) 0.96
Concise review: diabetes, the bone marrow niche, and impaired vascular regeneration. Stem Cells Transl Med (2014) 0.95
Activation of liver X receptor improves viability of adipose-derived mesenchymal stem cells to attenuate myocardial ischemia injury through TLR4/NF-κB and Keap-1/Nrf-2 signaling pathways. Antioxid Redox Signal (2014) 0.88
Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse. Biochem Biophys Res Commun (2014) 0.87
The secretome of MUSE cells contains factors that may play a role in regulation of stemness, apoptosis and immunomodulation. Cell Cycle (2016) 0.86
Nuclear receptors in neurodegenerative diseases. Neurobiol Dis (2014) 0.85
LXR Regulation of Brain Cholesterol: From Development to Disease. Trends Endocrinol Metab (2016) 0.81
Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum. Proc Natl Acad Sci U S A (2015) 0.81
Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity. J Neurosci (2015) 0.81
Estrogen receptor β and Liver X receptor β: biology and therapeutic potential in CNS diseases. Mol Psychiatry (2014) 0.81
Targeting cholesterol homeostasis to fight hearing loss: a new perspective. Front Aging Neurosci (2015) 0.80
Nuclear receptors in stem cells and their therapeutic potential. Adv Drug Deliv Rev (2010) 0.80
Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development (2015) 0.80
Current trends in oxysterol research. Biochem Soc Trans (2016) 0.79
Role of Liver X Receptor in AD Pathophysiology. PLoS One (2015) 0.79
Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi. J Biol Chem (2014) 0.79
Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration. F1000Prime Rep (2015) 0.78
Quantitative detection of free 24S-hydroxycholesterol, and 27-hydroxycholesterol from human serum. BMC Neurosci (2014) 0.77
Oxysterols drive dopaminergic neurogenesis from stem cells. Cell Stem Cell (2009) 0.76
Lxr regulates lipid metabolic and visual perception pathways during zebrafish development. Mol Cell Endocrinol (2015) 0.76
Nuclear receptors: Oxysterols detour to neurodevelopment. Nat Chem Biol (2013) 0.75
Liver X receptor-β improves autism symptoms via downregulation of β-amyloid expression in cortical neurons. Ital J Pediatr (2016) 0.75
Cholesterolomics: An update. Anal Biochem (2017) 0.75
Nuclear receptors in neural stem/progenitor cell homeostasis. Cell Mol Life Sci (2017) 0.75
Estrogen receptors: how do they signal and what are their targets. Physiol Rev (2007) 5.27
Principles for modulation of the nuclear receptor superfamily. Nat Rev Drug Discov (2004) 4.19
Estrogen signaling: a subtle balance between ER alpha and ER beta. Mol Interv (2003) 2.88
Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. Genome Biol (2004) 2.77
Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci (2009) 2.69
Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc Natl Acad Sci U S A (2004) 2.64
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell (2009) 2.53
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science (2002) 2.45
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol Endocrinol (2003) 2.38
Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature (2008) 2.24
International Union of Pharmacology. LXIV. Estrogen receptors. Pharmacol Rev (2006) 2.15
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Estrogen receptor beta: an overview and update. Nucl Recept Signal (2008) 1.97
An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice. Proc Natl Acad Sci U S A (2003) 1.93
An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth. Proc Natl Acad Sci U S A (2002) 1.82
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (2006) 1.79
Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab (2010) 1.78
Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites. Mol Cell Biol (2011) 1.77
Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res (2007) 1.77
Derivation of mouse embryonic stem cells. Nat Protoc (2006) 1.76
Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev (2005) 1.75
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2004) 1.74
Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity. Endocrinology (2003) 1.73
Transcriptional corepression by SHP: molecular mechanisms and physiological consequences. Trends Endocrinol Metab (2005) 1.71
ERBB2 amplification is superior to protein expression status in predicting patient outcome in serous ovarian carcinoma. Gynecol Oncol (2004) 1.70
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis. Endocrinology (2005) 1.69
Liver X receptor biology and pharmacology: new pathways, challenges and opportunities. Trends Pharmacol Sci (2012) 1.67
Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland. Proc Natl Acad Sci U S A (2004) 1.66
Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration. Proc Natl Acad Sci U S A (2002) 1.65
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11. Oncogene (2005) 1.65
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J Cell Sci (2007) 1.65
Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium. Proc Natl Acad Sci U S A (2002) 1.63
Dopamine D2 receptor knockout mice develop features of Parkinson disease. Ann Neurol (2009) 1.62
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism. J Biol Chem (2003) 1.61
Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development (2006) 1.58
Increased estrogen receptor betacx expression during mammary carcinogenesis. Clin Cancer Res (2005) 1.56
Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine. Cell Microbiol (2007) 1.55
Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest (2014) 1.55
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses. Nat Med (2009) 1.54
Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha. Proc Natl Acad Sci U S A (2006) 1.53
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Genes Dev (2010) 1.52
Isoflavone treatment for acute menopausal symptoms. Menopause (2007) 1.52
False positives in MALDI-TOF detection of ERbeta in mitochondria. Biochem Biophys Res Commun (2006) 1.51
Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate. Proc Natl Acad Sci U S A (2004) 1.51
Genome-wide identification of estrogen receptor alpha-binding sites in mouse liver. Mol Endocrinol (2007) 1.50
Role of estrogen receptor beta in colonic epithelium. Proc Natl Acad Sci U S A (2006) 1.49
Dragon ERE Finder version 2: A tool for accurate detection and analysis of estrogen response elements in vertebrate genomes. Nucleic Acids Res (2003) 1.49
Disruption of estrogen receptor beta gene impairs spatial learning in female mice. Proc Natl Acad Sci U S A (2002) 1.47
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A (2007) 1.46
Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice. Physiol Behav (2004) 1.45
Putative metabolic effects of the liver X receptor (LXR). Diabetes (2004) 1.44
Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain. Proc Natl Acad Sci U S A (2003) 1.44
ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. J Biol Chem (2002) 1.44
Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses. Immunity (2012) 1.44
Regulation of postnatal lung development and homeostasis by estrogen receptor beta. Mol Cell Biol (2003) 1.44
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. J Biol Chem (2005) 1.44
Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. J Biol Chem (2002) 1.43
Estrogen receptor (ER) beta modulates ERalpha-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters. Mol Endocrinol (2005) 1.42
Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors. J Clin Endocrinol Metab (2004) 1.41
Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. Mol Cell Biol (2005) 1.40
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice. Am J Physiol Endocrinol Metab (2008) 1.40
Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells. Cancer Res (2009) 1.40
Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice. Proc Natl Acad Sci U S A (2005) 1.40
Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation. Oncogene (2003) 1.39
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J Biol Chem (2002) 1.39
Enterococcus faecalis from newborn babies regulate endogenous PPARgamma activity and IL-10 levels in colonic epithelial cells. Proc Natl Acad Sci U S A (2008) 1.38
Lung dysfunction causes systemic hypoxia in estrogen receptor beta knockout (ERbeta-/-) mice. Proc Natl Acad Sci U S A (2006) 1.37
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3. Mol Endocrinol (2006) 1.36
Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis. Carcinogenesis (2004) 1.36
Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β. PLoS One (2012) 1.36
Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts. Cancer Res (2006) 1.35
Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells. Cancer Res (2007) 1.35
Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha. J Biol Chem (2002) 1.35
Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma. PLoS Genet (2008) 1.35
Estrogen receptor and aryl hydrocarbon receptor signaling pathways. Nucl Recept Signal (2006) 1.35
Accumulation of foam cells in liver X receptor-deficient mice. Circulation (2002) 1.34
A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia. Proc Natl Acad Sci U S A (2009) 1.33
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha. J Biol Chem (2003) 1.33
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc Natl Acad Sci U S A (2005) 1.33
Female sex and estrogen receptor-beta attenuate cardiac remodeling and apoptosis in pressure overload. Am J Physiol Regul Integr Comp Physiol (2010) 1.32
A previously uncharacterized role for estrogen receptor beta: defeminization of male brain and behavior. Proc Natl Acad Sci U S A (2005) 1.32
Disruption of the estrogen receptor beta gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis. Proc Natl Acad Sci U S A (2003) 1.32
A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary. Biol Reprod (2002) 1.31
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proc Natl Acad Sci U S A (2010) 1.31
Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice. J Clin Invest (2009) 1.29
Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest (2008) 1.29
Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation. Mol Endocrinol (2003) 1.28
Estrogen receptor-alpha and -beta immunoreactive neurons in the brainstem and spinal cord of male and female mice: relationships to monoaminergic, cholinergic, and spinal projection systems. J Comp Neurol (2005) 1.28
The genome landscape of ERalpha- and ERbeta-binding DNA regions. Proc Natl Acad Sci U S A (2008) 1.27
Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting. Mol Pharmacol (2006) 1.27
Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia. Proc Natl Acad Sci U S A (2008) 1.26