Published in J Exp Med on August 08, 2005
An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica | NCT00904826
Treatment Response Among Chinese Neuromyelitis Optica Spectrum Disorders (Momentum) | NCT04101058
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol (2011) 25.66
Astrocytes: biology and pathology. Acta Neuropathol (2009) 8.43
Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci (2009) 7.15
International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology (2015) 6.64
Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica. Ann Neurol (2009) 4.88
Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain (2010) 3.95
Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays. Neurology (2012) 3.79
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci (2008) 3.44
Neuromyelitis optica unique area postrema lesions: nausea, vomiting, and pathogenic implications. Neurology (2011) 3.30
AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance. Nat Rev Neurol (2010) 3.28
The spectrum of MOG autoantibody-associated demyelinating diseases. Nat Rev Neurol (2013) 3.13
Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain (2008) 2.96
Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med (2012) 2.90
Distinction of seropositive NMO spectrum disorder and MS brain lesion distribution. Neurology (2013) 2.77
Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. J Clin Invest (2006) 2.75
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nat Med (2007) 2.64
Development, maintenance and disruption of the blood-brain barrier. Nat Med (2013) 2.62
Aquaporin 4 and neuromyelitis optica. Lancet Neurol (2012) 2.58
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol (2012) 2.45
In vivo identification of morphologic retinal abnormalities in neuromyelitis optica. Neurology (2013) 2.43
Multiple sclerosis. J Clin Invest (2012) 2.41
Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders. J Neuroinflammation (2011) 2.35
Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation. J Clin Invest (2006) 2.32
Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. J Exp Med (2008) 2.26
Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J Neurosci (2009) 2.24
Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition. J Neurol Neurosurg Psychiatry (2012) 2.21
Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes. Proc Natl Acad Sci U S A (2011) 2.11
Aquaporin water channels in the nervous system. Nat Rev Neurosci (2013) 2.10
Reactive gliosis and the multicellular response to CNS damage and disease. Neuron (2014) 2.08
Neuromyelitis optica: potential roles for intravenous immunoglobulin. J Clin Immunol (2012) 2.06
Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem (2011) 1.98
Aquaporins in clinical medicine. Annu Rev Med (2012) 1.90
Prevalence of neuromyelitis optica spectrum disorder and phenotype distribution. J Neurol (2009) 1.88
Oligodendrocytes: biology and pathology. Acta Neuropathol (2009) 1.81
Diagnostic utility of aquaporin-4 in the analysis of active demyelinating lesions. Neurology (2014) 1.80
Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica. Acta Neuropathol (2013) 1.79
Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS). J Neurol (2013) 1.79
Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Ann Neurol (2012) 1.75
Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol (2011) 1.72
Patterns of antibody binding to aquaporin-4 isoforms in neuromyelitis optica. PLoS One (2010) 1.68
The complex genetics of multiple sclerosis: pitfalls and prospects. Brain (2008) 1.68
Treatment of Neuromyelitis Optica: Review and Recommendations. Mult Scler Relat Disord (2012) 1.62
Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica. PLoS Med (2007) 1.61
Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics (2010) 1.60
The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica. Brain Pathol (2014) 1.60
Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance. J Neuroinflammation (2010) 1.60
Variable responses to rituximab treatment in neuromyelitis optica (Devic's disease). Neurol Sci (2007) 1.59
A population-based study of neuromyelitis optica in Caucasians. Neurology (2011) 1.58
Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 protein assembly in orthogonal arrays. J Biol Chem (2012) 1.55
Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain. Ann Neurol (2012) 1.54
Astrocyte barriers to neurotoxic inflammation. Nat Rev Neurosci (2015) 1.53
Treatment of neuromyelitis optica: state-of-the-art and emerging therapies. Nat Rev Neurol (2014) 1.53
Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis. Neurology (2009) 1.52
Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation. FASEB J (2011) 1.50
Physiological roles of aquaporin-4 in brain. Physiol Rev (2013) 1.48
Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol (2012) 1.47
Aquaporins: important but elusive drug targets. Nat Rev Drug Discov (2014) 1.45
Aquaporin 4 molecular mimicry and implications for neuromyelitis optica. J Neuroimmunol (2013) 1.42
Neuromyelitis optica: clinical features, immunopathogenesis and treatment. Clin Exp Immunol (2014) 1.38
Intravenous neuromyelitis optica autoantibody in mice targets aquaporin-4 in peripheral organs and area postrema. PLoS One (2011) 1.38
NMO-IgG detected in CSF in seronegative neuromyelitis optica. Neurology (2009) 1.38
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. Acta Neuropathol (2010) 1.37
Evaluation of inner retinal layers in patients with multiple sclerosis or neuromyelitis optica using optical coherence tomography. Ophthalmology (2012) 1.34
Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells. J Biol Chem (2009) 1.34
The role of microbiome in central nervous system disorders. Brain Behav Immun (2013) 1.34
Neuromyelitis optica pathogenesis and aquaporin 4. J Neuroinflammation (2008) 1.32
Clinical and MRI features of Japanese patients with multiple sclerosis positive for NMO-IgG. J Neurol Neurosurg Psychiatry (2006) 1.31
Aquaporins: translating bench research to human disease. J Exp Biol (2009) 1.31
Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome. Autoimmunity (2009) 1.31
Mammalian aquaporins: diverse physiological roles and potential clinical significance. Expert Rev Mol Med (2008) 1.31
Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography. Mult Scler (2015) 1.30
The pathological spectrum of CNS inflammatory demyelinating diseases. Semin Immunopathol (2009) 1.29
Optimization of current and future therapy for autoimmune diseases. Nat Med (2012) 1.29
Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis. Neurol Neuroimmunol Neuroinflamm (2014) 1.29
Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss. Acta Neuropathol (2012) 1.28
Myasthenia gravis and neuromyelitis optica spectrum disorder: a multicenter study of 16 patients. Neurology (2012) 1.25
The history of neuromyelitis optica. J Neuroinflammation (2013) 1.25
Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis. PLoS One (2013) 1.21
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome. J Neuroinflammation (2016) 1.20
Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica. J Biol Chem (2011) 1.20
Impaired olfaction in mice lacking aquaporin-4 water channels. FASEB J (2008) 1.19
Current and future treatment approaches for neuromyelitis optica. Ther Adv Neurol Disord (2011) 1.19
Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis. PLoS One (2013) 1.18
Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab. Mod Rheumatol (2012) 1.17
Revised diagnostic criteria for neuromyelitis optica (NMO). Application in a series of suspected patients. J Neurol (2007) 1.17
Idiopathic inflammatory-demyelinating diseases of the central nervous system. Neuroradiology (2007) 1.16
Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays. J Autoimmun (2012) 1.16
Functions of aquaporins in the eye. Prog Retin Eye Res (2008) 1.16
Aquaporin-4 autoimmunity. Neurol Neuroimmunol Neuroinflamm (2015) 1.15
Familial neuromyelitis optica. Neurology (2010) 1.14
Functional characterization of aquaporin-4 specific T cells: towards a model for neuromyelitis optica. PLoS One (2011) 1.13
Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica. PLoS One (2010) 1.13
Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica. J Clin Invest (2013) 1.12
Development of extensive brain lesions following interferon beta therapy in relapsing neuromyelitis optica and longitudinally extensive myelitis. J Neurol (2007) 1.12
Early high-dose intravenous methylprednisolone is effective in preserving retinal nerve fiber layer thickness in patients with neuromyelitis optica. Graefes Arch Clin Exp Ophthalmol (2010) 1.11
Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica. FASEB J (2012) 1.10
Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. Arch Neurol (2009) 1.10
Neuromyelitis optica: an antibody-mediated disorder of the central nervous system. Neurol Res Int (2012) 1.10
Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding. J Biol Chem (2011) 1.10
New insights into neuromyelitis optica. J Clin Neurol (2011) 1.09
A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet (2004) 13.18
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol (2000) 9.73
The clinical course of neuromyelitis optica (Devic's syndrome). Neurology (1999) 8.03
A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain (2002) 6.85
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med (2000) 6.27
Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy. Nature (2002) 3.96
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J (2004) 3.80
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest (1997) 3.45
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proc Natl Acad Sci U S A (1994) 3.20
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem (1994) 2.85
Aquaporin water channels: molecular mechanisms for human diseases. FEBS Lett (2003) 2.47
Aquaporin-4 expression is increased in oedematous human brain tumours. J Neurol Neurosurg Psychiatry (2002) 2.42
Plasma exchange for severe attacks of CNS demyelination: predictors of response. Neurology (2002) 2.41
Neuromyelitis optica: clinical predictors of a relapsing course and survival. Neurology (2003) 2.28
Devic's neuromyelitis optica: a clinicopathological study of 8 patients. Ann Neurol (1993) 2.23
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice. Proc Natl Acad Sci U S A (2002) 1.97
Aquaporin-4 deficiency in skeletal muscle and brain of dystrophic mdx mice. FASEB J (2001) 1.84
Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease. J Clin Invest (2003) 1.80
Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport. Neuroscience (2004) 1.80
Passive transfer of autoimmune autonomic neuropathy to mice. J Neurosci (2004) 1.78
Devic's neuromyelitis optica: a prospective study of seven patients treated with prednisone and azathioprine. Neurology (1998) 1.53
Pure optic-spinal form of multiple sclerosis in Japan. Brain (2002) 1.41
Role of aquaporin-4 water channel in the development and integrity of the blood-brain barrier. J Cell Sci (2001) 1.28
Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier. Neuroreport (2001) 1.17
A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet (2004) 13.18
The spectrum of neuromyelitis optica. Lancet Neurol (2007) 11.83
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med (2000) 6.27
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest (2002) 4.97
Tracking of single fluorescent particles in three dimensions: use of cylindrical optics to encode particle position. Biophys J (1994) 4.77
Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol (1997) 4.53
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain (2007) 4.50
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem (2003) 4.40
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature (2005) 4.20
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. J Clin Invest (2005) 4.19
Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain (2010) 3.95
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J (2004) 3.80
Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys J (1998) 3.61
Determinants of the translational mobility of a small solute in cell cytoplasm. J Cell Biol (1993) 3.46
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest (1997) 3.45
Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem (2000) 3.29
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol (2004) 3.10
Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem (1998) 3.00
Crowding effects on diffusion in solutions and cells. Annu Rev Biophys (2008) 3.00
Adult-onset opsoclonus-myoclonus syndrome. Arch Neurol (2012) 2.95
Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome. Ann Neurol (2004) 2.91
Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem (1999) 2.91
Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. Kidney Int (2006) 2.89
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem (1994) 2.85
Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob disease. Arch Neurol (2008) 2.80
Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis. Ann Neurol (2006) 2.80
Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein. Cell Stress Chaperones (1996) 2.80
Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Natl Acad Sci U S A (1998) 2.73
Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry. J Cell Biol (1991) 2.73
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem (2010) 2.66
[(18)F]-fluorodeoxyglucose-positron emission tomography in patients with active myelopathy. Mayo Clin Proc (2013) 2.64
Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J (1999) 2.59
Aquaporin 4 and neuromyelitis optica. Lancet Neurol (2012) 2.58
Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem (1997) 2.56
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J Cell Sci (1995) 2.55
Autoimmune epilepsy: clinical characteristics and response to immunotherapy. Arch Neurol (2012) 2.49
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci (2005) 2.48
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol (2012) 2.45
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities. FEBS Lett (2001) 2.38
Mechanism and cellular applications of a green fluorescent protein-based halide sensor. J Biol Chem (2000) 2.38
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci U S A (1995) 2.37
Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica. Neurology (2013) 2.34
Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol (2005) 2.32
Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. J Exp Med (2008) 2.26
Intractable vomiting as the initial presentation of neuromyelitis optica. Ann Neurol (2010) 2.26
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. J Biol Chem (2003) 2.25
Localization of the CHIP28 water channel in rat kidney. Am J Physiol (1992) 2.17
Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol (2002) 2.16
The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J Biol Chem (1996) 2.16
Functional evaluation and cancer risk assessment of BRCA2 unclassified variants. Cancer Res (2005) 2.16
Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J Cell Biol (1998) 2.12
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proc Natl Acad Sci U S A (2001) 2.10
Glycine receptor autoimmune spectrum with stiff-man syndrome phenotype. JAMA Neurol (2013) 2.10
Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem (2005) 2.08
Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J (2006) 2.07
Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest (2000) 2.07
Aquaporins and cell migration. Pflugers Arch (2007) 2.02
Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder. Am J Physiol (1991) 2.01
Do not treat from CIS onset: evaluate disease course and prognosis first--yes. Mult Scler (2012) 2.01
Monte Carlo analysis of obstructed diffusion in three dimensions: application to molecular diffusion in organelles. Biophys J (1998) 2.00
Chronic pain as a manifestation of potassium channel-complex autoimmunity. Neurology (2012) 2.00
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. J Biol Chem (2001) 1.99
CFTR: folding, misfolding and correcting the ΔF508 conformational defect. Trends Mol Med (2011) 1.99
Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol (2003) 1.99
Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem (2011) 1.98
K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods (2005) 1.98
Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion. Biophys J (1998) 1.95
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A (2000) 1.94
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci (2004) 1.90
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem (2002) 1.89
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.87
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. J Clin Invest (1998) 1.87
Autoimmune dementia: clinical course and predictors of immunotherapy response. Mayo Clin Proc (2010) 1.85
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A (1998) 1.85
Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem (1992) 1.85
Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol Pharmacol (2007) 1.85
Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol (1993) 1.84
Three-dimensional organization of a human water channel. Nature (1997) 1.83
Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am J Physiol (1996) 1.82
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest (2001) 1.80
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol (2005) 1.80
Cytoplasmic viscosity near the cell plasma membrane: translational diffusion of a small fluorescent solute measured by total internal reflection-fluorescence photobleaching recovery. Biophys J (1996) 1.79
Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol (2003) 1.79
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. J Biol Chem (2002) 1.79
Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J Cell Sci (1997) 1.78
Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping. JAMA Neurol (2013) 1.78
Sleep manifestations of voltage-gated potassium channel complex autoimmunity. Arch Neurol (2011) 1.77
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorg Med Chem (2008) 1.75
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways. FASEB J (2004) 1.75
Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts. J Cell Biol (1992) 1.74
An outbreak of neurological autoimmunity with polyradiculoneuropathy in workers exposed to aerosolised porcine neural tissue: a descriptive study. Lancet Neurol (2009) 1.73
Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J (2006) 1.72
Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity. Biophys J (1990) 1.72
Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol (2011) 1.72
Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J (2010) 1.71
AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience (2009) 1.70
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem (2000) 1.70