Published in Cell on December 01, 1980
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Pattern of methylation of two genes coding for housekeeping functions. Proc Natl Acad Sci U S A (1983) 3.03
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells. Proc Natl Acad Sci U S A (1982) 2.92
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Phage particle-mediated gene transfer to cultured mammalian cells. Mol Cell Biol (1982) 2.47
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Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting. Proc Natl Acad Sci U S A (1983) 1.80
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Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol Cell Biol (1993) 1.57
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Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector. Proc Natl Acad Sci U S A (1984) 1.45
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High-frequency mutation at the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells due to deletion of the gene. Proc Natl Acad Sci U S A (1983) 1.09
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The 5'-flanking sequence of human interferon-beta 1 gene is responsible for viral induction of transcription. Nucleic Acids Res (1983) 1.08
Construction of microcell hybrid clones containing specific mouse chromosomes: application to autosomes 8 and 17. Mol Cell Biol (1982) 1.06
Molecular cloning of the mouse ouabain-resistance gene. Proc Natl Acad Sci U S A (1984) 1.01
Correction of a deletion mutant by gene targeting with an adenovirus vector. Mol Cell Biol (1993) 0.97
Transduction of the Chinese hamster ovary aprt gene by herpes simplex virus. J Virol (1984) 0.96
Chromosome-mediated gene transfer of hydroxyurea resistance and amplification of ribonucleotide reductase activity. Mol Cell Biol (1983) 0.95
Gene transfer method for transient gene expression, stable transformation, and cotransformation of suspension cell cultures. Mol Cell Biol (1985) 0.95
Analysis of signals controlling expression of the Chinese hamster ovary aprt gene. Mol Cell Biol (1988) 0.93
Comparison of phenotypic expression with genotypic transformation by using cloned, selectable markers. Mol Cell Biol (1982) 0.92
A novel selection system for recombinational and mutational events within an intron of a eucaryotic gene. Nucleic Acids Res (1990) 0.92
Stable expression of transfected Torpedo acetylcholine receptor alpha subunits in mouse fibroblast L cells. Proc Natl Acad Sci U S A (1987) 0.92
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DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135. Mol Cell Biol (1984) 0.88
Transcriptional activation of the adenine phosphoribosyltransferase promoter by an upstream butyrate-induced Moloney murine sarcoma virus enhancer-promoter element. J Virol (1990) 0.87
Structural alterations of the aprt locus induced by deoxyribonucleoside triphosphate pool imbalances in Chinese hamster ovary cells. Mol Cell Biol (1984) 0.85
DNA-mediated transfer of an RNA polymerase II gene: reversion of the temperature-sensitive hamster cell cycle mutant TsAF8 by mammalian DNA. Mol Cell Biol (1982) 0.83
Gene transfer in lymphoid cells: expression of the Thy-1.2 antigen by Thy-1.1 BW5147 lymphoma cells transfected with unfractionated cellular DNA. Proc Natl Acad Sci U S A (1984) 0.82
Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes. Mol Cell Biol (1983) 0.81
Carcinogen-induced trans activation of gene expression. Mol Cell Biol (1988) 0.80
Complementation of a methotrexate uptake defect in Chinese hamster ovary cells by DNA-mediated gene transfer. Mol Cell Biol (1989) 0.79
v-abl activates embryonic globin gene expression in mouse erythroleukemia cells. Proc Natl Acad Sci U S A (1986) 0.75
Gene rescue in plants by direct gene transfer of total genomic DNA into protoplasts. Nucleic Acids Res (1992) 0.75
The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell (1986) 22.26
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc Natl Acad Sci U S A (1979) 21.22
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell (1978) 19.44
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell (1977) 18.95
A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell (1991) 18.19
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region. Cell (1981) 12.73
Intragenic DNA spacers interrupt the ovalbumin gene. Proc Natl Acad Sci U S A (1978) 11.03
Visualizing an olfactory sensory map. Cell (1996) 8.79
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell (1985) 7.16
A spatial map of olfactory receptor expression in the Drosophila antenna. Cell (1999) 6.42
A soluble form of CD4 (T4) protein inhibits AIDS virus infection. Nature (1988) 6.39
The transfer and stable integration of the HSV thymidine kinase gene into mouse cells. Cell (1978) 6.38
Allelic inactivation regulates olfactory receptor gene expression. Cell (1994) 5.93
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Proc Natl Acad Sci U S A (1991) 5.83
A novel ras-related gene family. Cell (1985) 5.81
Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene. Proc Natl Acad Sci U S A (1985) 5.40
An olfactory sensory map in the fly brain. Cell (2000) 5.29
Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei. Proc Natl Acad Sci U S A (1976) 5.27
Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences. Cell (1984) 5.12
A novel family of genes encoding putative pheromone receptors in mammals. Cell (1995) 4.88
Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature (1990) 4.81
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A chemosensory gene family encoding candidate gustatory and olfactory receptors in Drosophila. Cell (2001) 4.64
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The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytes. Cell (1985) 3.91
Altering genotype and phenotype by DNA-mediated gene transfer. Science (1980) 3.82
Integration, transcription, and control of a Drosophila heat shock gene in mouse cells. Proc Natl Acad Sci U S A (1981) 3.70
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Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell (1993) 3.53
Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1987) 3.50
Isolation of a cDNA for human acid alpha-glucosidase and detection of genetic heterogeneity for mRNA in three alpha-glucosidase-deficient patients. Proc Natl Acad Sci U S A (1986) 3.49
Transformation of mammalian cells with an amplifiable dominant-acting gene. Proc Natl Acad Sci U S A (1980) 3.39
Specific sites of interaction between histones and DNA in chromatin. Proc Natl Acad Sci U S A (1974) 3.25
Cleavage of DNA in nuclei and chromatin with staphylococcal nuclease. Biochemistry (1975) 3.20
Analysis of DNA of isolated chromatin subunits. Proc Natl Acad Sci U S A (1975) 3.17
Molecular characterization of a functional cDNA encoding the serotonin 1c receptor. Science (1988) 3.02
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Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature (1987) 2.89
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The regulated expression of beta-globin genes introduced into mouse erythroleukemia cells. Cell (1983) 2.75
Degradation of cellular mRNA during infection by herpes simplex virus. Proc Natl Acad Sci U S A (1977) 2.72
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Circulating progesterone levels and ongoing pregnancy rates in controlled ovarian stimulation cycles for in vitro fertilization: analysis of over 4000 cycles. Hum Reprod (2010) 2.65
Co-ordinate regulation of herpes simplex virus gene expression is mediated by the functional interaction of two immediate early gene products. J Mol Biol (1986) 2.65
Odorant receptors govern the formation of a precise topographic map. Cell (1998) 2.60
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development. Mol Cell Biol (2001) 2.60
Regulated expression of human growth hormone genes in mouse cells. Cell (1982) 2.58
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity. J Virol (1995) 2.56
Role of the F-box protein Skp2 in lymphomagenesis. Proc Natl Acad Sci U S A (2001) 2.55
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Requirement of protein synthesis for the degradation of host mRNA in Friend erythroleukemia cells infected wtih herpes simplex virus type 1. J Virol (1978) 2.51
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An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development (1994) 2.46
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Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. Proc Natl Acad Sci U S A (1999) 2.39
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Increasing uterine receptivity by decreasing estradiol levels during the preimplantation period in high responders with the use of a follicle-stimulating hormone step-down regimen. Fertil Steril (1998) 2.35
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Presence in human breast cancer of RNA homologous to mouse mammary tumour virus RNA. Nature (1972) 2.31
Molecular cloning and nucleotide sequence of the streptavidin gene. Nucleic Acids Res (1986) 2.30
Portability issues for a structured clinical vocabulary: mapping from Yale to the Columbia medical entities dictionary. J Am Med Inform Assoc (1996) 2.24
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Resident pulmonary lymphocytes expressing the gamma/delta T-cell receptor. Nature (1989) 2.16
Clinical diagnosis of Down's syndrome. Clin Genet (1976) 2.10
A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties. Neuron (1990) 2.10
The gene encoding the T-cell surface protein T4 is located on human chromosome 12. Proc Natl Acad Sci U S A (1986) 2.08
Differential expression of the ras gene family in mice. Mol Cell Biol (1987) 2.07
A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene. Proc Natl Acad Sci U S A (1984) 2.07
Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons. Neuron (1992) 2.04