Published in Bioorg Med Chem Lett on November 17, 2003
Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Biochemistry (2006) 1.06
Autoinducer-2 and QseC control biofilm formation and in vivo virulence of Aggregatibacter actinomycetemcomitans. Infect Immun (2010) 1.03
A naturally occurring brominated furanone covalently modifies and inactivates LuxS. Bioorg Med Chem Lett (2009) 0.99
Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. Protein Sci (2010) 0.86
Arginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species. Anal Chem (2013) 0.84
Transcriptional regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK operons and their role in biofilm formation. J Bacteriol (2012) 0.83
Small molecule inhibitors of AI-2 signaling in bacteria: state-of-the-art and future perspectives for anti-quorum sensing agents. Int J Mol Sci (2013) 0.81
Differential transcriptional regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK operons by integration host factor protein. J Bacteriol (2014) 0.80
S-Ribosylhomocysteine analogs containing a [4-thio]ribose ring. Carbohydr Res (2015) 0.78
Zoosporic plant pathogens produce bacterial autoinducer-2 that affects Vibrio harveyi quorum sensing. FEMS Microbiol Lett (2009) 0.78
Synthesis and characterization of Se-adenosyl-L-selenohomocysteine selenoxide. J Sulphur Chem (2015) 0.75
S-Ribosylhomocysteine Analogues Modified at the Ribosyl C-4 Position. J Sulphur Chem (2016) 0.75
Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae. PLoS Genet (2017) 0.75
New Weapons to Fight Old Enemies: Novel Strategies for the (Bio)control of Bacterial Biofilms in the Food Industry. Front Microbiol (2016) 0.75
Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol (2005) 13.88
The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell (2004) 8.89
Structural identification of a bacterial quorum-sensing signal containing boron. Nature (2002) 8.11
Bacterial quorum-sensing network architectures. Annu Rev Genet (2009) 6.14
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci U S A (2002) 6.10
Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol (2003) 5.46
Bacterial small-molecule signaling pathways. Science (2006) 5.14
Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. Cell (2002) 5.12
LuxS quorum sensing: more than just a numbers game. Curr Opin Microbiol (2003) 3.76
Bacterial quorum sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med (2012) 3.65
The major Vibrio cholerae autoinducer and its role in virulence factor production. Nature (2007) 3.57
Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Mol Cell (2004) 3.36
Three parallel quorum-sensing systems regulate gene expression in Vibrio harveyi. J Bacteriol (2004) 3.30
Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. J Bacteriol (2005) 2.64
LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology (2002) 2.61
CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae. Mol Microbiol (2005) 2.56
Quorum sensing regulates type III secretion in Vibrio harveyi and Vibrio parahaemolyticus. J Bacteriol (2004) 2.55
Interspecies communication in bacteria. J Clin Invest (2003) 2.55
Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell (2006) 2.48
Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium. Mol Microbiol (2003) 2.47
A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A (2013) 2.46
Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. J Bacteriol (2008) 2.45
Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth. Mol Microbiol (2006) 2.43
Quantifying the integration of quorum-sensing signals with single-cell resolution. PLoS Biol (2009) 2.40
Multiple small RNAs act additively to integrate sensory information and control quorum sensing in Vibrio harveyi. Genes Dev (2007) 2.33
Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria. ACS Chem Biol (2007) 2.20
An open letter to Elias Zerhouni. Science (2005) 2.19
Interference with AI-2-mediated bacterial cell-cell communication. Nature (2005) 2.17
Bacterial social engagements. Trends Cell Biol (2004) 2.17
The Vibrio harveyi quorum-sensing system uses shared regulatory components to discriminate between multiple autoinducers. Genes Dev (2006) 2.17
Regulatory small RNAs circumvent the conventional quorum sensing pathway in pandemic Vibrio cholerae. Proc Natl Acad Sci U S A (2007) 2.13
The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters. Mol Microbiol (2008) 2.11
Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi. Cell (2008) 2.10
Vibrio harveyi quorum sensing: a coincidence detector for two autoinducers controls gene expression. EMBO J (2003) 1.99
Chemical communication among bacteria. Proc Natl Acad Sci U S A (2003) 1.98
Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell (2005) 1.94
AphA and LuxR/HapR reciprocally control quorum sensing in vibrios. Genes Dev (2011) 1.79
A negative feedback loop involving small RNAs accelerates Vibrio cholerae's transition out of quorum-sensing mode. Genes Dev (2008) 1.74
Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proc Natl Acad Sci U S A (2013) 1.71
A fitness trade-off between local competition and dispersal in Vibrio cholerae biofilms. Proc Natl Acad Sci U S A (2011) 1.59
Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism. Mol Microbiol (2010) 1.56
A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Mol Cell (2009) 1.55
Negative feedback loops involving small regulatory RNAs precisely control the Vibrio harveyi quorum-sensing response. Mol Cell (2010) 1.52
A strategy for antagonizing quorum sensing. Mol Cell (2011) 1.47
A small-RNA-mediated negative feedback loop controls quorum-sensing dynamics in Vibrio harveyi. Mol Microbiol (2008) 1.47
An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases. Anal Biochem (2006) 1.47
An expeditious synthesis of DPD and boron binding studies. Org Lett (2005) 1.45
Mob psychology. J Bacteriol (2002) 1.40
Information processing and signal integration in bacterial quorum sensing. Mol Syst Biol (2009) 1.39
Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing. EMBO J (2009) 1.37
Distinct sensory pathways in Vibrio cholerae El Tor and classical biotypes modulate cyclic dimeric GMP levels to control biofilm formation. J Bacteriol (2008) 1.33
Quorum-sensing non-coding small RNAs use unique pairing regions to differentially control mRNA targets. Mol Microbiol (2012) 1.32
Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Mol Microbiol (2011) 1.31
An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases. Anal Biochem (2004) 1.30
Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. J Biol Chem (2005) 1.26
The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nat Chem Biol (2009) 1.26
The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori. J Bacteriol (2007) 1.26
Cutting through the complexity of cell collectives. Proc Biol Sci (2013) 1.20
Active regulation of receptor ratios controls integration of quorum-sensing signals in Vibrio harveyi. Mol Syst Biol (2011) 1.19
Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. ACS Chem Biol (2011) 1.19
A genetically encoded photocaged Nepsilon-methyl-L-lysine. Mol Biosyst (2010) 1.17
Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases. J Am Chem Soc (2010) 1.16
Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J Biol Chem (2002) 1.15
Individual and combined roles of the master regulators AphA and LuxR in control of the Vibrio harveyi quorum-sensing regulon. J Bacteriol (2012) 1.15
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor. J Bacteriol (2011) 1.13
Bgp, a secreted glycosaminoglycan-binding protein of Borrelia burgdorferi strain N40, displays nucleosidase activity and is not essential for infection of immunodeficient mice. Infect Immun (2006) 1.13
Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proc Natl Acad Sci U S A (2010) 1.12
The impact of single nucleotide polymorphisms on human aldehyde oxidase. Drug Metab Dispos (2012) 1.12
The small nucleoid protein Fis is involved in Vibrio cholerae quorum sensing. Mol Microbiol (2006) 1.12
Substrate profiling of PRMT1 reveals amino acid sequences that extend beyond the "RGG" paradigm. Biochemistry (2008) 1.11
AI-1 influences the kinase activity but not the phosphatase activity of LuxN of Vibrio harveyi. J Biol Chem (2006) 1.11
Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. PLoS Pathog (2012) 1.11
Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell. Biophys J (2010) 1.11
The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives. Mol Biosyst (2011) 1.10
Structure and catalytic properties of the most complex intergrown zeolite ITQ-39 determined by electron crystallography. Nat Chem (2012) 1.08
Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis. J Mol Biol (2005) 1.08
Observing bacteria through the lens of social evolution. J Biol (2008) 1.08
Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry. Anal Chem (2010) 1.05
Synthesis of proteins with defined posttranslational modifications using the genetic noncanonical amino acid incorporation approach. Mol Biosyst (2010) 1.05
A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation. Anal Biochem (2002) 1.04
Functional determinants of the quorum-sensing non-coding RNAs and their roles in target regulation. EMBO J (2013) 1.03
Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications. Bioorg Med Chem Lett (2009) 1.02
Synthesis of an extra-large molecular sieve using proton sponges as organic structure-directing agents. Proc Natl Acad Sci U S A (2013) 1.02
Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes. Pharm Res (2004) 1.01
Desulfurization of cysteine-containing peptides resulting from sample preparation for protein characterization by mass spectrometry. Rapid Commun Mass Spectrom (2010) 1.00
Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning. J Biol Chem (2010) 0.99
A convenient method for genetic incorporation of multiple noncanonical amino acids into one protein in Escherichia coli. Mol Biosyst (2010) 0.99
A naturally occurring brominated furanone covalently modifies and inactivates LuxS. Bioorg Med Chem Lett (2009) 0.99
Photoswitchable nanoparticles enable high-resolution cell imaging: PULSAR microscopy. J Am Chem Soc (2008) 0.98
Alternating DNA and pi-conjugated sequences. Thermophilic foldable polymers. J Am Chem Soc (2003) 0.97
Synthesis of LuxS inhibitors targeting bacterial cell-cell communication. Org Lett (2004) 0.96
Chemo-enzymatic detection of protein isoaspartate using protein isoaspartate methyltransferase and hydrazine trapping. Anal Chem (2008) 0.95
Ligand and antagonist driven regulation of the Vibrio cholerae quorum-sensing receptor CqsS. Mol Microbiol (2012) 0.94
Carbocyclic pyrimidine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase. Bioorg Med Chem (2006) 0.94
Quorum regulatory small RNAs repress type VI secretion in Vibrio cholerae. Mol Microbiol (2014) 0.92