Published in Cancer Res on November 01, 2003
Preventing re-replication of chromosomal DNA. Nat Rev Mol Cell Biol (2005) 5.82
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. Proc Natl Acad Sci U S A (2008) 3.29
Replication licensing and cancer--a fatal entanglement? Nat Rev Cancer (2008) 2.86
Rif1 regulates the replication timing domains on the human genome. EMBO J (2012) 1.87
Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage. Mol Biol Cell (2007) 1.65
Mining for coexpression across hundreds of datasets using novel rank aggregation and visualization methods. Genome Biol (2009) 1.52
Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells. Cell Cycle (2009) 1.49
Selective killing of cancer cells by suppression of geminin activity. Cancer Res (2009) 1.33
Cdk2 is required for p53-independent G2/M checkpoint control. PLoS Genet (2010) 1.21
Origin licensing and p53 status regulate Cdk2 activity during G(1). Cell Cycle (2009) 1.20
The functional role of Cdc6 in S-G2/M in mammalian cells. EMBO Rep (2006) 1.16
Functional domains of the Xenopus replication licensing factor Cdt1. Nucleic Acids Res (2005) 1.16
Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor. Mol Cell Biol (2011) 1.06
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment. Nat Cell Biol (2012) 1.05
Molecular architecture of the DNA replication origin activation checkpoint. EMBO J (2010) 1.04
Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis. J Cell Sci (2006) 1.01
Dormant origins, the licensing checkpoint, and the response to replicative stresses. Cold Spring Harb Perspect Biol (2012) 0.99
Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle. Oncogene (2010) 0.94
H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing. Nucleic Acids Res (2015) 0.92
HOXD13 binds DNA replication origins to promote origin licensing and is inhibited by geminin. Mol Cell Biol (2009) 0.87
The licensing checkpoint opens up. Cell Cycle (2009) 0.86
Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells. J Cell Biol (2006) 0.85
Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast. J Cell Sci (2006) 0.85
MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity. Mol Biol Int (2014) 0.85
Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival. Mol Biol Cell (2009) 0.84
Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression. J Med Microbiol (2008) 0.83
The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffolds. PLoS One (2014) 0.81
mRNA expression of the DNA replication-initiation proteins in epithelial dysplasia and squamous cell carcinoma of the tongue. BMC Cancer (2008) 0.79
Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS Genet (2016) 0.77
Behavior of replication origins in Eukaryota - spatio-temporal dynamics of licensing and firing. Cell Cycle (2015) 0.76
A Role of hIPI3 in DNA Replication Licensing in Human Cells. PLoS One (2016) 0.75
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines. Cell Chem Biol (2017) 0.75
Genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation. Proc Natl Acad Sci U S A (2011) 1.85
Water stress-responsive genes in loblolly pine (Pinus taeda) roots identified by analyses of expressed sequence tag libraries. Tree Physiol (2006) 1.51
Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast. Cell (2002) 1.44
Elevated matrix metalloproteinase expression after stent implantation is associated with restenosis. Int J Cardiol (2005) 1.43
Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle (2010) 1.43
Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p. J Cell Biol (2003) 1.15
Unique features of nuclear mRNA poly(A) signals and alternative polyadenylation in Chlamydomonas reinhardtii. Genetics (2008) 1.15
Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways. Basic Res Cardiol (2008) 1.07
Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells. Arterioscler Thromb Vasc Biol (2005) 1.06
Human ISCA1 interacts with IOP1/NARFL and functions in both cytosolic and mitochondrial iron-sulfur protein biogenesis. J Biol Chem (2009) 1.04
IKKalpha regulates the mitotic phase of the cell cycle by modulating Aurora A phosphorylation. Cell Cycle (2006) 1.04
Sequence analysis of bacterial artificial chromosome clones from the apospory-specific genomic region of Pennisetum and Cenchrus. Plant Physiol (2008) 1.03
Pairwise interactions of the six human MCM protein subunits. J Mol Biol (2004) 1.01
An annotated genetic map of loblolly pine based on microsatellite and cDNA markers. BMC Genet (2011) 1.01
Active cochlear amplification is dependent on supporting cell gap junctions. Nat Commun (2013) 1.00
Sorghum expressed sequence tags identify signature genes for drought, pathogenesis, and skotomorphogenesis from a milestone set of 16,801 unique transcripts. Plant Physiol (2005) 0.98
Risk of cardiac dysfunction with trastuzumab in breast cancer patients: a meta-analysis. Cancer Treat Rev (2010) 0.98
Autographa californica multiple nucleopolyhedrovirus 38K is a novel nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself. J Virol (2008) 0.98
Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6. J Biol Chem (2010) 0.95
17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells. J Steroid Biochem Mol Biol (2006) 0.95
Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. Int Immunopharmacol (2012) 0.92
CBrowse: a SAM/BAM-based contig browser for transcriptome assembly visualization and analysis. Bioinformatics (2012) 0.91
The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells. Cell Cycle (2010) 0.90
Circulating miR-214 is associated with the severity of coronary artery disease. J Geriatr Cardiol (2013) 0.90
A simple and efficient method for extracting DNA from old and burned bone. J Forensic Sci (2004) 0.89
AGEs increased migration and inflammatory responses of adventitial fibroblasts via RAGE, MAPK and NF-kappaB pathways. Atherosclerosis (2009) 0.89
Genome-wide analysis of tandem repeats in plants and green algae. G3 (Bethesda) (2014) 0.88
Concerted action of the new Genomic Peptide Finder and AUGUSTUS allows for automated proteogenomic annotation of the Chlamydomonas reinhardtii genome. Proteomics (2011) 0.88
Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast. J Cell Sci (2010) 0.88
Potent adjuvantic activity of a CCR1-agonistic bis-quinoline. Bioorg Med Chem Lett (2011) 0.88
Origin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae. J Biol Chem (2008) 0.88
Effectiveness of a national transitional care program in reducing acute care use. J Am Geriatr Soc (2014) 0.87
Discrimination of cinnamon bark and cinnamon twig samples sourced from various countries using HPLC-based fingerprint analysis. Food Chem (2011) 0.87
MAGIC database and interfaces: an integrated package for gene discovery and expression. Comp Funct Genomics (2004) 0.87
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading. Nucleic Acids Res (2011) 0.86
Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways. Atherosclerosis (2009) 0.85
Triterpene compounds isolated from Acer mandshuricum and their anti-inflammatory activity. Bioorg Med Chem Lett (2010) 0.85
Ctf4p facilitates Mcm10p to promote DNA replication in budding yeast. Biochem Biophys Res Commun (2010) 0.85
Vitamin E ameliorates ox-LDL-induced foam cells formation through modulating the activities of oxidative stress-induced NF-κB pathway. Mol Cell Biochem (2011) 0.84
Association analysis between the Cdc6 G1321A polymorphism and the risk for non-Hodgkin lymphoma and hepatocellular carcinoma. Mutat Res (2008) 0.84
A MATLAB-based tool for accurate detection of perfect overlapping and nested inverted repeats in DNA sequences. Bioinformatics (2013) 0.83
Ciglitazone inhibits oxidized-low density lipoprotein induced immune maturation of dendritic cells. J Cardiovasc Pharmacol (2004) 0.82
Ecdysone induces transcription and amplification in Sciara coprophila DNA puff II/9A. Dev Biol (2006) 0.82
Ssanghwa-tang, an oriental herbal cocktail, exerts anti-melanogenic activity by suppression of the p38 MAPK and PKA signaling pathways in B16F10 cells. BMC Complement Altern Med (2013) 0.81
Upregulation of lectinlike oxidized low-density lipoprotein receptor-1 expression contributes to the vein graft atherosclerosis: modulation by losartan. Atherosclerosis (2004) 0.80
Addressing the unmet need for visualizing conditional random fields in biological data. BMC Bioinformatics (2014) 0.80
A naturally enhanced green fluorescent protein from magnificent sea anemone (Heteractis magnifica) and its functional analysis. Biochem Biophys Res Commun (2003) 0.80
A DNase I hypersensitive site flanks an origin of DNA replication and amplification in Sciara. Chromosoma (2002) 0.80
ATP-dependent pre-replicative complex assembly is facilitated by Adk1p in budding yeast. J Biol Chem (2010) 0.80
Phenolic compounds from Artemisia iwayomogi and their effects on osteoblastic MC3T3-E1 cells. Biol Pharm Bull (2010) 0.79
Vicious cycle composed of gut flora and visceral fat: a novel explanation of the initiation and progression of atherosclerosis. Med Hypotheses (2007) 0.79
Myelodysplastic syndrome associated with clopidogrel: a case report. Int J Clin Pharmacol Ther (2012) 0.79
[Effect of advanced glycation end products on the function and angiogenesis of adipose tissue-derived stem cells and the protective effect of danhong injection: an experimental study]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2014) 0.79
Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex. J Cell Sci (2012) 0.79
Far3p domains involved in the interactions of Far proteins and pheromone-induced cell cycle arrest in budding yeast. FEMS Yeast Res (2010) 0.79
[Comparative study on algorithms for wave-front aberration reconstruction of human eye]. Guang Pu Xue Yu Guang Pu Fen Xi (2010) 0.79
mRNA expression of the DNA replication-initiation proteins in epithelial dysplasia and squamous cell carcinoma of the tongue. BMC Cancer (2008) 0.79
The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis. Cell Cycle (2012) 0.78
Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen-activated protein kinases. BMC Complement Altern Med (2014) 0.78
Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity. Biochem Biophys Res Commun (2003) 0.78
New camptothecin and ellagic acid analogues from the root bark of Camptotheca acuminata. Planta Med (2004) 0.78
Gene expression analysis of CL-20-induced reversible neurotoxicity reveals GABA(A) receptors as potential targets in the earthworm Eisenia fetida. Environ Sci Technol (2012) 0.78
High-resolution retinal imaging with micro adaptive optics system. Appl Opt (2011) 0.78
Extraction of poly(A) sites from large-scale RNA-Seq data. Methods Mol Biol (2015) 0.78
[Evaluation of genomic amplification of the human telomerase RNA component gene in the screening of cervical lesions]. Zhonghua Fu Chan Ke Za Zhi (2008) 0.77
Comparative analysis of error-prone replication mononucleotide repeats across baculovirus genomes. Virus Res (2013) 0.77
Effect of serum interleukin 21 on the development of coronary artery disease. APMIS (2014) 0.77
Randomized Comparison of 3 Hemostasis Techniques After Transradial Coronary Intervention. J Cardiovasc Nurs (2016) 0.77
Oxidized high-density lipoprotein impairs endothelial progenitor cells' function by activation of CD36-MAPK-TSP-1 pathways. Antioxid Redox Signal (2014) 0.76
Study on CCR5 analogs and affinity peptides. Protein Eng Des Sel (2012) 0.76
PeanutDB: an integrated bioinformatics web portal for Arachis hypogaea transcriptomics. BMC Plant Biol (2012) 0.76
Pattern analysis approach reveals restriction enzyme cutting abnormalities and other cDNA library construction artifacts using raw EST data. BMC Biotechnol (2012) 0.76
ERK5 knock down aggravates detrimental effects of hypothermal stimulation on cardiomyocytes via Bim upregulation. Environ Toxicol Pharmacol (2013) 0.76
[Effects of shexiang baoxin pill on function and nitric oxide secretion of endothelial progenitor cells]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2009) 0.76
Evidence of airborne transmission of SARS. N Engl J Med (2004) 0.75
APOE genotype-function relationship: evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes risk. PLoS One (2011) 0.75
Y-chromosomal haplotyping of single sperm cells isolated from semen mixtures - a successful identification of three perpetrators in a multi-suspect sexual assault case. Croat Med J (2014) 0.75
Myocardial bridging is a potential risk factor of very late stent thrombosis of drug eluting stent. Med Sci Monit (2012) 0.75
[Comparative study on the performance of deformable mirror of NIR based human eye aberration correction system]. Guang Pu Xue Yu Guang Pu Fen Xi (2012) 0.75
Protective effect of silymarin against rapamycin-induced apoptosis and proliferation inhibition in endothelial progenitor cells. Nat Prod Commun (2015) 0.75
Corrigendum: Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing. Sci Rep (2017) 0.75
[Increased lectin-like oxidized low density lipoprotein receptor-1 expression in the autologous vein grafts and vein graft atherosclerosis]. Zhonghua Xin Xue Guan Bing Za Zhi (2006) 0.75
[Regulation of [12Asp]K-ras4B on transcriptional activity of estrogen receptor in endometrial carcinoma HEC-1A cell lines]. Zhonghua Fu Chan Ke Za Zhi (2004) 0.75
[Regulation of human progesterone receptor isoforms A and B in uterine endometrial carcinoma by estrogen and insulin-like growth factor-1]. Zhonghua Yi Xue Za Zhi (2002) 0.75
Effect of interleukin-2 level and genetic variants on coronary artery disease. Inflammation (2013) 0.75
Comparison of the time to onset of action on myocardial ischaemia following intravenous administration of isosorbide dinitrate and 5-isosorbide mononitrate in Chinese patients. Arzneimittelforschung (2004) 0.75
Soluble expression of a strong thrombolytic pro-urokinase mutant in Escherichia coli. Protein Expr Purif (2006) 0.75
[Applications of DNA identification technology in protection of wild animals]. Fa Yi Xue Za Zhi (2011) 0.75
Reduced T-Cell Thymic Export Reflected by sj-TREC in Patients with Coronary Artery Disease. J Atheroscler Thromb (2016) 0.75
Aspirin as a promising drug for slow coronary flow. Med Hypotheses (2012) 0.75
[High-concentration palmitic acid inhibits the proliferation of peripheral blood-derived human endothelial progenitor cells in vitro]. Nan Fang Yi Ke Da Xue Xue Bao (2008) 0.75
[Evaluation on cardio-ankle vascular index derived from ultrasound]. Zhonghua Xin Xue Guan Bing Za Zhi (2008) 0.75
[Algorithm of locally adaptive region growing based on multi-template matching applied to automated detection of hemorrhages]. Guang Pu Xue Yu Guang Pu Fen Xi (2013) 0.75
Mitoxantrone suppresses vascular smooth muscle cell proliferation and balloon injury-induced neointima formation: An in vitro and in vivo study. Bosn J Basic Med Sci (2017) 0.75
[Genetic polymorphism of penta e locus in four Chinese nationalities]. Yi Chuan (2006) 0.75
Dysfunction of AQP7 in the periadventitial fat: A novel trigger of atherosclerosis. Med Hypotheses (2007) 0.75
[Time-dependent and dose-dependent regulation of human progesterone receptor isoforms A and B in uterine endometrial carcinoma by human insulin-like growth factor-I]. Zhonghua Fu Chan Ke Za Zhi (2002) 0.75
[Clinical application of telomerase RNA component gene amplification assay in cervical lesions.]. Zhonghua Fu Chan Ke Za Zhi (2009) 0.75