Published in Annu Rev Genet on January 01, 2003
Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Mol Biol Cell (2004) 2.48
Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J Cell Biol (2007) 2.18
APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol Biol Cell (2005) 2.14
Pericentric chromatin is an elastic component of the mitotic spindle. Curr Biol (2007) 2.10
Kinetochore orientation during meiosis is controlled by Aurora B and the monopolin complex. Cell (2007) 2.00
The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci U S A (2010) 1.98
Activation of the DNA damage checkpoint in yeast lacking the histone chaperone anti-silencing function 1. Mol Cell Biol (2004) 1.94
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly. EMBO J (2006) 1.81
Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure. BMC Cell Biol (2005) 1.75
Kinetochore microtubule interaction during S phase in Saccharomyces cerevisiae. Genes Dev (2007) 1.72
The origins and evolution of functional modules: lessons from protein complexes. Philos Trans R Soc Lond B Biol Sci (2006) 1.71
An overview of Cdk1-controlled targets and processes. Cell Div (2010) 1.66
The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation. Chromosome Res (2004) 1.60
Retracted Role of senescence and mitotic catastrophe in cancer therapy. Cell Div (2010) 1.51
Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice. J Cell Biol (2009) 1.51
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Mol Cell Biol (2006) 1.50
Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol Biol Cell (2005) 1.49
The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae. Genetics (2004) 1.49
Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores. Genes Dev (2007) 1.45
Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts. Dev Biol (2008) 1.43
On the number of steady states in a multiple futile cycle. J Math Biol (2007) 1.39
The kinetochore protein Ndc10p is required for spindle stability and cytokinesis in yeast. Proc Natl Acad Sci U S A (2005) 1.34
Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.34
DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet (2008) 1.31
De novo kinetochore assembly requires the centromeric histone H3 variant. Mol Biol Cell (2005) 1.30
Kinetochore-microtubule interactions: steps towards bi-orientation. EMBO J (2010) 1.30
The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.30
Analysis of the subcellular localization, function, and proteolytic control of the Arabidopsis cyclin-dependent kinase inhibitor ICK1/KRP1. Plant Physiol (2006) 1.28
Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics (2005) 1.26
The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles. Genetics (2005) 1.25
Spindle poisons and cell fate: a tale of two pathways. Mol Interv (2011) 1.24
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.24
Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis. Cancer Res (2009) 1.23
Linking kinetochore-microtubule binding to the spindle checkpoint. Dev Cell (2008) 1.21
Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism. Curr Biol (2010) 1.20
The protein phosphatase 2A functions in the spindle position checkpoint by regulating the checkpoint kinase Kin4. Genes Dev (2009) 1.20
Novel response to microtubule perturbation in meiosis. Mol Cell Biol (2005) 1.17
A cell cycle timer for asymmetric spindle positioning. PLoS Biol (2009) 1.16
Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.16
Emerging roles for centromeres in meiosis I chromosome segregation. Nat Rev Genet (2008) 1.14
Mouse emi1 has an essential function in mitotic progression during early embryogenesis. Mol Cell Biol (2006) 1.13
CtBPs promote cell survival through the maintenance of mitotic fidelity. Mol Cell Biol (2009) 1.12
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. Curr Biol (2009) 1.12
Msc1 acts through histone H2A.Z to promote chromosome stability in Schizosaccharomyces pombe. Genetics (2007) 1.12
Evaluating putative mechanisms of the mitotic spindle checkpoint. Proc Natl Acad Sci U S A (2005) 1.12
Mitotic exit and separation of mother and daughter cells. Genetics (2012) 1.10
Cell cycle checkpoint regulators reach a zillion. Cell Cycle (2013) 1.10
Schizosaccharomyces pombe Bub3 is dispensable for mitotic arrest following perturbed spindle formation. Genetics (2008) 1.07
The chromosome cycle: coordinating replication and segregation. Second in the cycles review series. EMBO Rep (2005) 1.06
The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint. Mol Biol Cell (2006) 1.06
Chromosome bi-orientation on the mitotic spindle. Philos Trans R Soc Lond B Biol Sci (2005) 1.05
Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms. Proc Natl Acad Sci U S A (2010) 1.05
Atypical regulation of a green lineage-specific B-type cyclin-dependent kinase. Plant Physiol (2005) 1.05
Phosphoserines on maize CENTROMERIC HISTONE H3 and histone H3 demarcate the centromere and pericentromere during chromosome segregation. Plant Cell (2005) 1.03
Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae. Mol Biol Cell (2008) 1.02
Elm1 kinase activates the spindle position checkpoint kinase Kin4. J Cell Biol (2010) 1.01
Uncovering novel cell cycle players through the inactivation of securin in budding yeast. Genetics (2004) 1.00
The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function. Mol Biol Cell (2004) 0.99
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1. Mol Cell Biol (2004) 0.99
Tem1 localization to the spindle pole bodies is essential for mitotic exit and impairs spindle checkpoint function. J Cell Biol (2011) 0.99
Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit. Biochem J (2005) 0.98
Noise resistance in the spindle assembly checkpoint. Mol Syst Biol (2006) 0.96
The coordination of centromere replication, spindle formation, and kinetochore-microtubule interaction in budding yeast. PLoS Genet (2008) 0.96
RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans. J Cell Biol (2007) 0.95
Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation. Genetics (2004) 0.94
The mitotic exit network Mob1p-Dbf2p kinase complex localizes to the nucleus and regulates passenger protein localization. Mol Biol Cell (2005) 0.94
Histone h3 exerts a key function in mitotic checkpoint control. Mol Cell Biol (2009) 0.93
Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap. Bioessays (2012) 0.93
Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis. PLoS Genet (2012) 0.93
Consequences of defective tubulin folding on heterodimer levels, mitosis and spindle morphology in Saccharomyces cerevisiae. Genetics (2006) 0.93
A characterization of scale invariant responses in enzymatic networks. PLoS Comput Biol (2012) 0.93
The spindle assembly checkpoint regulates the phosphorylation state of a subset of DNA checkpoint proteins in Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.92
A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis. J Cell Biol (2005) 0.92
Meiosis-driven genome variation in plants. Curr Genomics (2007) 0.92
The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation. Genetics (2006) 0.92
Spindle position is coordinated with cell-cycle progression through establishment of mitotic exit-activating and -inhibitory zones. Mol Cell (2010) 0.91
Live-cell analysis of kinetochore-microtubule interaction in budding yeast. Methods (2010) 0.91
Cyclin G1 regulates the outcome of taxane-induced mitotic checkpoint arrest. Oncogene (2011) 0.90
Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae. Genetics (2005) 0.90
Signaling pathways of ESE-16, an antimitotic and anticarbonic anhydrase estradiol analog, in breast cancer cells. PLoS One (2013) 0.89
Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae. Eukaryot Cell (2004) 0.87
Novel role for Cdc14 sequestration: Cdc14 dephosphorylates factors that promote DNA replication. Mol Cell Biol (2006) 0.87
Ran GTPase regulates Mad2 localization to the nuclear pore complex. Eukaryot Cell (2005) 0.86
The centrosome and asymmetric cell division. Prion (2009) 0.86
Fly meets yeast: checking the correct orientation of cell division. Trends Cell Biol (2011) 0.86
The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling. Nat Commun (2015) 0.86
Budding yeast dma proteins control septin dynamics and the spindle position checkpoint by promoting the recruitment of the Elm1 kinase to the bud neck. PLoS Genet (2012) 0.85
The spindle position checkpoint in budding yeast: the motherly care of MEN. Cell Div (2006) 0.85
In vivo characterization of the nonessential budding yeast anaphase-promoting complex/cyclosome components Swm1p, Mnd2p and Apc9p. Genetics (2005) 0.84
Hym1p affects cell cycle progression in Saccharomyces cerevisiae. Curr Genet (2004) 0.84
A dominant interfering Bub1 mutant is insufficient to induce or alter thymic tumorigenesis in vivo, even in a sensitized genetic background. Mol Cell Biol (2005) 0.84
Stable preanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck. Eukaryot Cell (2007) 0.82
Decoding ubiquitin for mitosis. Genes Cancer (2012) 0.82
SepBCTF4 is required for the formation of DNA-damage-induced UvsCRAD51 foci in Aspergillus nidulans. Genetics (2005) 0.82
The energy costs of insulators in biochemical networks. Biophys J (2013) 0.82
A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae. Curr Genet (2004) 0.82
Anaphase-promoting complex in Caenorhabditis elegans. Mol Cell Biol (2004) 0.81
Saccharomyces CDK1 phosphorylates Rad53 kinase in metaphase, influencing cellular morphogenesis. J Biol Chem (2009) 0.81
Differential regulation of anaphase promoting complex/cyclosome substrates by the spindle assembly checkpoint in Saccharomyces cerevisiae. Genetics (2008) 0.80
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev (2003) 3.04
Applications of orthogonal "click" chemistries in the synthesis of functional soft materials. Chem Rev (2009) 2.28
The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. Cell Cycle (2002) 1.63
DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet (2008) 1.31
The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.30
Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics (2005) 1.26
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.24
Eliminating gene conversion improves high-throughput genetics in Saccharomyces cerevisiae. Genetics (2005) 1.07
The immortal strand hypothesis: how could it work? Cell (2008) 1.03
Pmr1, a Golgi Ca2+/Mn2+-ATPase, is a regulator of the target of rapamycin (TOR) signaling pathway in yeast. Proc Natl Acad Sci U S A (2006) 0.96
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint. Genes Dev (2012) 0.96
Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae. Genetics (2007) 0.92
Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. Curr Biol (2009) 0.90
A Hec of a microtubule attachment. Nat Struct Mol Biol (2007) 0.89
Assaying the spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Methods Mol Biol (2004) 0.89
Use of yeast chemigenomics and COXEN informatics in preclinical evaluation of anticancer agents. Neoplasia (2011) 0.89
Differential kinetochore requirements for establishment and maintenance of the spindle checkpoint are dependent on the mechanism of checkpoint activation in Saccharomyces cerevisiae. Cell Cycle (2004) 0.83
Isolation of yeast genomic DNA for southern blot analysis. CSH Protoc (2006) 0.82
Novel interactions between actin and the proteasome revealed by complex haploinsufficiency. PLoS Genet (2011) 0.82
A redundant function for the N-terminal tail of Ndc80 in kinetochore-microtubule interaction in Saccharomyces cerevisiae. Genetics (2012) 0.81
Differential regulation of anaphase promoting complex/cyclosome substrates by the spindle assembly checkpoint in Saccharomyces cerevisiae. Genetics (2008) 0.80
Assay of β-Galactosidase in Yeast: Permeabilized Cell Assay. CSH Protoc (2006) 0.80
Yeast DNA isolation: miniprep. CSH Protoc (2006) 0.79
Analyzing the spindle checkpoint in yeast and frogs. Methods Mol Biol (2004) 0.79
Yeast RNA isolation: small-scale. CSH Protoc (2006) 0.79
High-efficiency transformation of yeast. CSH Protoc (2006) 0.79
Actin staining in fixed yeast cells. CSH Protoc (2006) 0.78
Yeast Vital Stains: DAPI Stain of Nuclear and Mitochondrial DNA. CSH Protoc (2006) 0.78
Sister chromatids segregate at mitosis without mother-daughter bias in Saccharomyces cerevisiae. Genetics (2012) 0.77
Random spore analysis in yeast. CSH Protoc (2006) 0.77
Tetrad dissection. CSH Protoc (2006) 0.77
Yeast vital stains: calcofluor staining of chitin and bud scars. CSH Protoc (2006) 0.77
"Quick and dirty" plasmid transformation of yeast colonies. CSH Protoc (2006) 0.77
Inducing yeast cell synchrony: hydroxyurea arrest. CSH Protoc (2006) 0.76
Assay of β-Galactosidase in Yeast: Freeze/Thaw Assay by Chemiluminescence in 96-Well Plates. CSH Protoc (2006) 0.76
Yeast colony PCR. CSH Protoc (2006) 0.76
Inducing Yeast Cell Synchrony: α-Factor Arrest Using bar1 Mutants. CSH Protoc (2006) 0.75
Assay of β-Galactosidase in Yeast: Freeze/Thaw Assay by Chemiluminescence in Microcentrifuge Tubes. CSH Protoc (2006) 0.75
Yeast DNA isolation: midiprep. CSH Protoc (2006) 0.75
Isolation of plasmid DNA from yeast cells: a ten-minute preparation. CSH Protoc (2006) 0.75
Inducing yeast cell synchrony: nocodazole arrest. CSH Protoc (2006) 0.75
Measuring yeast cell density by spectrophotometry. CSH Protoc (2006) 0.75
Preparation of genomic DNA from yeast using glass beads. CSH Protoc (2006) 0.75
Making a tetrad dissection needle. CSH Protoc (2006) 0.75
Determining plating efficiency in yeast: indirect method. CSH Protoc (2006) 0.75
Plate assay for carboxypeptidase y in yeast cells. CSH Protoc (2006) 0.75
Chromatin immunoprecipitation in yeast. CSH Protoc (2006) 0.75
Yeast Vital Stains: Visualizing Vacuoles and Endocytic Compartments with FM4-64. CSH Protoc (2006) 0.75
Logarithmic growth. CSH Protoc (2006) 0.75
PCR-Mediated Gene Disruption: One-Step Method. CSH Protoc (2006) 0.75
Inducing Yeast Cell Synchrony: α-Factor Arrest Using Low pH. CSH Protoc (2006) 0.75
Tandem Affinity Protein (TAP) Purification from Yeast. CSH Protoc (2006) 0.75
Inducing Yeast Cell Synchrony: α-Factor Arrest Using Low Cell Concentration. CSH Protoc (2006) 0.75
Hydroxylamine mutagenesis of plasmid DNA. CSH Protoc (2006) 0.75
Yeast protein extracts. CSH Protoc (2006) 0.75
Yeast immunofluorescence. CSH Protoc (2006) 0.75
Yeast Vital Stains: Visualizing Mitochondria with DiOC6 or DiIC5(3). CSH Protoc (2006) 0.75
Inducing yeast cell synchrony: dilution of stationary-phase cultures. CSH Protoc (2006) 0.75
Ethyl Methane Sulfonate (EMS) Mutagenesis. CSH Protoc (2006) 0.75
Yeast RNA isolation: large-scale. CSH Protoc (2006) 0.75
Assay of β-Galactosidase in Yeast: Assay of Crude Extracts. CSH Protoc (2006) 0.75
Preparation of yeast cells for flow cytometry. CSH Protoc (2006) 0.75
Picking zygotes. CSH Protoc (2006) 0.75
Determining plating efficiency in yeast: direct method. CSH Protoc (2006) 0.75