Published in Mol Biol Cell on October 05, 2005
The life and miracles of kinetochores. EMBO J (2009) 4.59
Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing. BMC Genomics (2009) 3.22
Pericentric chromatin is organized into an intramolecular loop in mitosis. Curr Biol (2008) 2.33
CENP-A exceeds microtubule attachment sites in centromere clusters of both budding and fission yeast. J Cell Biol (2011) 2.04
The kinetochore. Cold Spring Harb Perspect Biol (2014) 1.64
Plasticity of fission yeast CENP-A chromatin driven by relative levels of histone H3 and H4. PLoS Genet (2007) 1.41
DNA binding of centromere protein C (CENPC) is stabilized by single-stranded RNA. PLoS Genet (2010) 1.38
Pericentromeric sister chromatid cohesion promotes kinetochore biorientation. Mol Biol Cell (2009) 1.31
Towards building a chromosome segregation machine. Nature (2010) 1.25
A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosome. BMC Genet (2009) 1.19
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol Biol Cell (2009) 1.19
The composition, functions, and regulation of the budding yeast kinetochore. Genetics (2013) 1.15
The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4. EMBO J (2011) 1.11
Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One (2009) 1.11
Condensin function at centromere chromatin facilitates proper kinetochore tension and ensures correct mitotic segregation of sister chromatids. Genes Cells (2007) 1.09
The CNA1 histone of the ciliate Tetrahymena thermophila is essential for chromosome segregation in the germline micronucleus. Mol Biol Cell (2005) 1.05
The requirement for the Dam1 complex is dependent upon the number of kinetochore proteins and microtubules. Curr Biol (2011) 1.02
Endogenous transcription at the centromere facilitates centromere activity in budding yeast. Curr Biol (2011) 1.00
CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans. Mol Microbiol (2011) 0.92
The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation. Genetics (2006) 0.92
Histone H3 localizes to the centromeric DNA in budding yeast. PLoS Genet (2012) 0.92
Gcn5p plays an important role in centromere kinetochore function in budding yeast. Mol Cell Biol (2007) 0.91
Live-cell analysis of kinetochore-microtubule interaction in budding yeast. Methods (2010) 0.91
A coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicans. PLoS Genet (2012) 0.89
SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae. PLoS Genet (2012) 0.86
Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast. Genetics (2013) 0.80
Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects. PLoS Genet (2016) 0.78
Re-replication of a centromere induces chromosomal instability and aneuploidy. PLoS Genet (2015) 0.78
Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization. Proc Natl Acad Sci U S A (2015) 0.78
A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. PLoS Genet (2016) 0.77
Synergistic Control of Kinetochore Protein Levels by Psh1 and Ubr2. PLoS Genet (2016) 0.76
Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment. Mol Biol Cell (2015) 0.76
The unconventional kinetoplastid kinetochore: from discovery toward functional understanding. Biochem Soc Trans (2016) 0.75
The interplay between chromosome stability and cell cycle control explored through gene-gene interaction and computational simulation. Nucleic Acids Res (2016) 0.75
Sir protein-independent repair of dicentric chromosomes in Saccharomyces cerevisiae. Mol Biol Cell (2016) 0.75
Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions. G3 (Bethesda) (2016) 0.75
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast (1998) 48.29
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev (1997) 7.81
Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs. Cell (1982) 7.01
Uninterrupted MCM2-7 function required for DNA replication fork progression. Science (2000) 6.27
Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell (1998) 5.43
NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae. J Cell Biol (1993) 4.96
A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes Dev (1995) 4.93
A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell (1991) 4.88
Functional analysis of kinetochore assembly in Caenorhabditis elegans. J Cell Biol (2001) 4.82
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev (1999) 4.69
The case for epigenetic effects on centromere identity and function. Trends Genet (1997) 4.57
Heat-inducible degron: a method for constructing temperature-sensitive mutants. Science (1994) 4.42
Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast. Cell (2000) 4.35
Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science (2000) 4.33
Heterochromatic deposition of centromeric histone H3-like proteins. Proc Natl Acad Sci U S A (2000) 4.27
Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell (1995) 4.23
Microbial determinations by flow cytometry. J Gen Microbiol (1979) 4.01
A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones. J Cell Biol (1987) 3.92
Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeast. Cell (2000) 3.70
Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell (2004) 3.68
Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell (2001) 3.67
The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions. Nat Cell Biol (2001) 3.59
Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice. Proc Natl Acad Sci U S A (2000) 3.53
Phylogenomics of the nucleosome. Nat Struct Biol (2003) 3.52
Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev (2003) 3.51
A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore. Genes Dev (1999) 3.50
Determining centromere identity: cyclical stories and forking paths. Nat Rev Genet (2001) 3.39
Structure, function, and regulation of budding yeast kinetochores. Annu Rev Cell Dev Biol (2003) 3.32
Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J Cell Biol (2003) 3.18
A histone-H3-like protein in C. elegans. Nature (1999) 3.14
The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J (2001) 3.02
Genetic manipulation of centromere function. Mol Cell Biol (1987) 2.97
Molecular mechanisms of kinetochore capture by spindle microtubules. Nature (2005) 2.90
The spindle assembly and spindle position checkpoints. Annu Rev Genet (2003) 2.84
Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J Cell Sci (2001) 2.82
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis. J Cell Biol (2001) 2.72
Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. Plant Cell (2002) 2.72
Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr Biol (1996) 2.71
Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J (2002) 2.68
Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle. Nature (2004) 2.64
The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev (2002) 2.60
Centromeric retroelements and satellites interact with maize kinetochore protein CENH3. Plant Cell (2002) 2.55
Stable kinetochore-microtubule attachment constrains centromere positioning in metaphase. Curr Biol (2004) 2.48
Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Curr Biol (2004) 2.38
Detecting and measuring cotranslational protein degradation in vivo. Science (2000) 2.34
The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain. Mol Cell Biol (2000) 2.08
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1. Mol Cell Biol (2005) 2.00
An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell (2003) 1.90
Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics (2001) 1.89
Condensin restructures chromosomes in preparation for meiotic divisions. J Cell Biol (2004) 1.85
The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex. J Cell Biol (1999) 1.84
Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrity. Mol Biol Cell (2001) 1.70
Analysis of primary structural determinants that distinguish the centromere-specific function of histone variant Cse4p from histone H3. Mol Cell Biol (1999) 1.67
Captivating capture: how microtubules attach to kinetochores. Curr Biol (2003) 1.62
Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.61
Histone-histone interactions and centromere function. Mol Cell Biol (2000) 1.49
A delay in the Saccharomyces cerevisiae cell cycle that is induced by a dicentric chromosome and dependent upon mitotic checkpoints. Mol Cell Biol (1992) 1.31
The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centromere protein essential for chromosome transmission. Proc Natl Acad Sci U S A (2002) 1.26
Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J Cell Biol (2003) 1.21
The Drosophila melanogaster condensin subunit Cap-G interacts with the centromere-specific histone H3 variant CID. Chromosoma (2004) 1.10
Identification of xenopus CENP-A and an associated centromeric DNA repeat. Mol Biol Cell (2005) 1.03
The spindle checkpoint: tension versus attachment. Trends Cell Biol (2005) 3.63
The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores. Nat Cell Biol (2005) 3.61
The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage. Cell (2006) 3.45
Tension directly stabilizes reconstituted kinetochore-microtubule attachments. Nature (2010) 2.99
Centromere identity is specified by a single centromeric nucleosome in budding yeast. Proc Natl Acad Sci U S A (2007) 2.58
Histone variants: deviants? Genes Dev (2005) 2.50
Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Curr Biol (2004) 2.38
Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. Mol Biol Cell (2002) 2.26
Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores. Curr Biol (2012) 2.00
The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol (2003) 1.99
Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2009) 1.91
An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell (2003) 1.90
An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain. Mol Cell (2010) 1.78
The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nat Struct Mol Biol (2012) 1.76
Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev (2014) 1.65
Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast. Curr Biol (2009) 1.61
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Mol Cell Biol (2006) 1.50
A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly. Dev Cell (2007) 1.48
Pericentromeric sister chromatid cohesion promotes kinetochore biorientation. Mol Biol Cell (2009) 1.31
Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae. Genetics (2009) 1.10
Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanisms. Proc Natl Acad Sci U S A (2013) 0.98
Microtubule capture: a concerted effort. Cell (2006) 0.96
The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation. Genetics (2006) 0.92
The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast. Genetics (2013) 0.88
Cdc14-dependent dephosphorylation of a kinetochore protein prior to anaphase in Saccharomyces cerevisiae. Genetics (2010) 0.87
The Mub1/Ubr2 ubiquitin ligase complex regulates the conserved Dsn1 kinetochore protein. PLoS Genet (2013) 0.86
The Helicobacter pylori autotransporter ImaA (HP0289) modulates the immune response and contributes to host colonization. Infect Immun (2012) 0.86
An efficient purification system for native minichromosome from Saccharomyces cerevisiae. Methods Mol Biol (2012) 0.84
Conserved transcriptional unit organization of the cag pathogenicity island among Helicobacter pylori strains. Front Cell Infect Microbiol (2012) 0.84
Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast. Genetics (2013) 0.80
Reconstituting the kinetochore–microtubule interface: what, why, and how. Chromosoma (2012) 0.78
Top-SUMO wrestles centromeric cohesion. Dev Cell (2002) 0.77
Correcting SYNful attachments. Nat Cell Biol (2004) 0.76
Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (2007) 0.75
Sue Biggins: how kinetochores keep control of mitosis. Interview by Caitlin Sedwick. J Cell Biol (2012) 0.75
Corrigendum: Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2016) 0.75