Published in Nat Struct Mol Biol on January 01, 2007
Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1). Curr Biol (2008) 2.38
Linking kinetochore-microtubule binding to the spindle checkpoint. Dev Cell (2008) 1.21
The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat Struct Mol Biol (2006) 4.62
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol (2004) 6.61
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature (2008) 3.77
Protein architecture of the human kinetochore microtubule attachment site. Cell (2009) 3.68
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
Aurora B is enriched at merotelic attachment sites, where it regulates MCAK. Curr Biol (2006) 3.22
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol (2002) 3.17
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol Cell (2005) 3.14
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science (2010) 3.13
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev (2003) 3.04
The spindle assembly and spindle position checkpoints. Annu Rev Genet (2003) 2.84
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56
Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1). Curr Biol (2008) 2.38
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol (2004) 2.31
Phosphorylation regulates SIRT1 function. PLoS One (2008) 2.30
Applications of orthogonal "click" chemistries in the synthesis of functional soft materials. Chem Rev (2009) 2.28
Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation. Science (2008) 2.28
The reversibility of mitotic exit in vertebrate cells. Nature (2006) 2.16
Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition. Cell (2007) 1.97
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly. J Cell Biol (2008) 1.91
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr Biol (2005) 1.88
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. Dev Cell (2006) 1.71
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. Mol Biol Cell (2007) 1.66
The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis. Cell Cycle (2002) 1.63
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. Mol Biol Cell (2005) 1.52
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci U S A (2004) 1.51
Complement activation on B lymphocytes opsonized with rituximab or ofatumumab produces substantial changes in membrane structure preceding cell lysis. J Immunol (2008) 1.46
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. Chromosoma (2007) 1.32
DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet (2008) 1.31
The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.30
Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics (2005) 1.26
Spindle poisons and cell fate: a tale of two pathways. Mol Interv (2011) 1.24
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.24
Linking kinetochore-microtubule binding to the spindle checkpoint. Dev Cell (2008) 1.21
Timing of events in mitosis. Curr Biol (2002) 1.20
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment. Cell (2007) 1.17
Multimodal microtubule binding by the Ndc80 kinetochore complex. Nat Struct Mol Biol (2012) 1.15
The Ndc80 complex: integrating the kinetochore's many movements. Chromosome Res (2011) 1.11
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. Curr Biol (2009) 1.08
Eliminating gene conversion improves high-throughput genetics in Saccharomyces cerevisiae. Genetics (2005) 1.07
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein. J Cell Biol (2011) 1.07
Cep57, a multidomain protein with unique microtubule and centrosomal localization domains. Biochem J (2008) 1.06
The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement. Mol Biol Cell (2011) 1.05
The immortal strand hypothesis: how could it work? Cell (2008) 1.03
Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. Mol Biol Cell (2008) 1.02
Pmr1, a Golgi Ca2+/Mn2+-ATPase, is a regulator of the target of rapamycin (TOR) signaling pathway in yeast. Proc Natl Acad Sci U S A (2006) 0.96
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint. Genes Dev (2012) 0.96
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. Chromosoma (2008) 0.94
Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae. Genetics (2007) 0.92
Aurora-A kinase and inhibitor-2 regulate the cyclin threshold for mitotic entry in Xenopus early embryonic cell cycles. Cell Cycle (2006) 0.92
Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell (2012) 0.91
Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. Curr Biol (2009) 0.90
The kinetochore NUPtials. Nat Cell Biol (2003) 0.90
Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor. Biochemistry (2012) 0.90
Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. Biochemistry (2007) 0.89
Use of yeast chemigenomics and COXEN informatics in preclinical evaluation of anticancer agents. Neoplasia (2011) 0.89
Assaying the spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Methods Mol Biol (2004) 0.89
EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B. J Cell Biol (2014) 0.89
Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers. Eur J Immunol (2011) 0.88
Differential kinetochore requirements for establishment and maintenance of the spindle checkpoint are dependent on the mechanism of checkpoint activation in Saccharomyces cerevisiae. Cell Cycle (2004) 0.83
Novel interactions between actin and the proteasome revealed by complex haploinsufficiency. PLoS Genet (2011) 0.82
Isolation of yeast genomic DNA for southern blot analysis. CSH Protoc (2006) 0.82
The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts. Nucleus (2015) 0.81
A redundant function for the N-terminal tail of Ndc80 in kinetochore-microtubule interaction in Saccharomyces cerevisiae. Genetics (2012) 0.81
Structural features and chaperone activity of the NudC protein family. J Mol Biol (2011) 0.81
Differential regulation of anaphase promoting complex/cyclosome substrates by the spindle assembly checkpoint in Saccharomyces cerevisiae. Genetics (2008) 0.80
Assay of β-Galactosidase in Yeast: Permeabilized Cell Assay. CSH Protoc (2006) 0.80
Yeast RNA isolation: small-scale. CSH Protoc (2006) 0.79
Analyzing the spindle checkpoint in yeast and frogs. Methods Mol Biol (2004) 0.79
Yeast DNA isolation: miniprep. CSH Protoc (2006) 0.79
High-efficiency transformation of yeast. CSH Protoc (2006) 0.79
Actin staining in fixed yeast cells. CSH Protoc (2006) 0.78
Purification of the Ndc80 kinetochore subcomplex from Xenopus eggs. Methods Mol Biol (2005) 0.78
Yeast Vital Stains: DAPI Stain of Nuclear and Mitochondrial DNA. CSH Protoc (2006) 0.78
Sister chromatids segregate at mitosis without mother-daughter bias in Saccharomyces cerevisiae. Genetics (2012) 0.77
Yeast vital stains: calcofluor staining of chitin and bud scars. CSH Protoc (2006) 0.77
Random spore analysis in yeast. CSH Protoc (2006) 0.77
Cdt1 throws kinetochore-microtubule attachments for a loop. Nat Cell Biol (2012) 0.77
"Quick and dirty" plasmid transformation of yeast colonies. CSH Protoc (2006) 0.77
Tetrad dissection. CSH Protoc (2006) 0.77
Probing kinetochore structure and function using Xenopus laevis frog egg extracts. Methods Mol Biol (2009) 0.76
Yeast colony PCR. CSH Protoc (2006) 0.76
Assay of β-Galactosidase in Yeast: Freeze/Thaw Assay by Chemiluminescence in 96-Well Plates. CSH Protoc (2006) 0.76
Inducing yeast cell synchrony: hydroxyurea arrest. CSH Protoc (2006) 0.76
Xenopus egg extracts as a simplified model system for structure-function studies of dynein regulators. Methods Mol Biol (2014) 0.75
Inducing Yeast Cell Synchrony: α-Factor Arrest Using bar1 Mutants. CSH Protoc (2006) 0.75
The quest for the holy "G" of chromosomal passengers. Dev Cell (2003) 0.75
A new histone at the centromere? Cell (2012) 0.75
Cell division: righting the check. Curr Biol (2009) 0.75
Isolation of plasmid DNA from yeast cells: a ten-minute preparation. CSH Protoc (2006) 0.75
Yeast DNA isolation: midiprep. CSH Protoc (2006) 0.75
Preparation of genomic DNA from yeast using glass beads. CSH Protoc (2006) 0.75
Preparation of yeast cells for flow cytometry. CSH Protoc (2006) 0.75