Published in J Am Chem Soc on November 26, 2003
A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity. Proc Natl Acad Sci U S A (2007) 1.56
Selective detection of mercury (II) ion using nonlinear optical properties of gold nanoparticles. J Am Chem Soc (2008) 1.29
Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. Inorg Chem (2006) 1.05
Kinetically controlled photoinduced electron transfer switching in Cu(I)-responsive fluorescent probes. J Am Chem Soc (2010) 0.99
Turn-on and ratiometric mercury sensing in water with a red-emitting probe. J Am Chem Soc (2007) 0.94
Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides. J Am Chem Soc (2006) 0.93
Phosphorescent sensor for biological mobile zinc. J Am Chem Soc (2011) 0.85
A highly selective and sensitive inorganic/organic hybrid polymer fluorescence "turn-on" chemosensory system for iron cations. J Am Chem Soc (2006) 0.83
Development of fluorescent probes for bioimaging applications. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.82
A portable and power-free microfluidic device for rapid and sensitive lead (Pb2+) detection. Sensors (Basel) (2012) 0.81
Fluorescence Sensing of Zinc and Mercury Ions with Hydrophilic 1,2,3-Triazolyl Fluorene Probes. Chem Mater (2010) 0.76
Fluorescent and Magnetic Mesoporous Hybrid Material: A Chemical and Biological Nanosensor for Hg(2+) Ions. Sci Rep (2016) 0.75
Dual-rhodamine urea derivative, a novel chemidosimeter for Hg(II) and its application in imaging Hg(II) in living cells. J Biol Inorg Chem (2009) 0.75
Naked-eye and Selective Detection of Mercury (II) Ions in Mixed Aqueous Media Using a Cellulose-based Support. Sensors (Basel) (2007) 0.75
Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov (2005) 9.47
Synthetic models for non-heme carboxylate-bridged diiron metalloproteins: strategies and tactics. Chem Rev (2004) 3.73
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc Natl Acad Sci U S A (2008) 3.62
Direct cellular responses to platinum-induced DNA damage. Chem Rev (2007) 3.42
Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(IV) anticancer drug design. J Am Chem Soc (2007) 2.82
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (2013) 2.61
Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. J Am Chem Soc (2008) 2.40
Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res (2006) 2.37
Visualization of nitric oxide in living cells by a copper-based fluorescent probe. Nat Chem Biol (2006) 2.33
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A (2010) 2.21
Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. J Am Chem Soc (2009) 2.16
Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc Natl Acad Sci U S A (2011) 2.16
Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. Acc Chem Res (2009) 2.07
Dioxygen activation in soluble methane monooxygenase. Acc Chem Res (2011) 2.07
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes Dev (2010) 1.95
Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins. Acc Chem Res (2006) 1.93
Mechanistic studies on the hydroxylation of methane by methane monooxygenase. Chem Rev (2003) 1.89
New metal complexes as potential therapeutics. Curr Opin Chem Biol (2003) 1.89
Inhibition of transcription by platinum antitumor compounds. Metallomics (2009) 1.88
A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. Cancer Res (2010) 1.79
Tools and tactics for the optical detection of mercuric ion. Chem Rev (2008) 1.77
Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem (2009) 1.71
Synthesis, characterization, and cytotoxicity of a series of estrogen-tethered platinum(IV) complexes. Chem Biol (2004) 1.66
cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proc Natl Acad Sci U S A (2008) 1.62
Characterization of the arene-oxidizing intermediate in ToMOH as a diiron(III) species. J Am Chem Soc (2007) 1.60
Imaging mobile zinc in biology. Curr Opin Chem Biol (2010) 1.57
Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing. Proc Natl Acad Sci U S A (2007) 1.53
Consequences of cisplatin binding on nucleosome structure and dynamics. Chem Biol (2010) 1.51
Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy. Inorg Chem (2006) 1.50
Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. J Am Chem Soc (2007) 1.50
Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages. Proc Natl Acad Sci U S A (2008) 1.49
Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile. Proc Natl Acad Sci U S A (2012) 1.48
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature. Bioconjug Chem (2007) 1.46
Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols. J Am Chem Soc (2012) 1.46
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proc Natl Acad Sci U S A (2002) 1.45
Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases. Acc Chem Res (2007) 1.43
Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate. Proc Natl Acad Sci U S A (2009) 1.43
Bacterial nitric-oxide synthases operate without a dedicated redox partner. J Biol Chem (2008) 1.41
The interface of inorganic chemistry and biology. J Am Chem Soc (2010) 1.41
X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc Natl Acad Sci U S A (2010) 1.39
X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase. Biochemistry (2006) 1.38
Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethers. J Am Chem Soc (2005) 1.38
Dioxygen activation in methane monooxygenase: a theoretical study. J Am Chem Soc (2004) 1.38
Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand. Inorg Chem (2003) 1.35
Membrane-permeable and -impermeable sensors of the Zinpyr family and their application to imaging of hippocampal zinc in vivo. Chem Biol (2004) 1.33
Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes. Chem Soc Rev (2010) 1.33
Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. J Am Chem Soc (2006) 1.32
Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proc Natl Acad Sci U S A (2013) 1.30
Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450. Proc Natl Acad Sci U S A (2003) 1.30
ZP4, an improved neuronal Zn2+ sensor of the Zinpyr family. J Am Chem Soc (2003) 1.29
Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron (2011) 1.29
New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensor. J Am Chem Soc (2008) 1.28
A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proc Natl Acad Sci U S A (2004) 1.27
Nucleotide excision repair from site-specifically platinum-modified nucleosomes. Biochemistry (2003) 1.27
Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathway. Biochemistry (2009) 1.26
Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate Q. J Am Chem Soc (2002) 1.25
Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis. Proc Natl Acad Sci U S A (2011) 1.25
Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. J Am Chem Soc (2010) 1.24
Modeling dioxygen-activating centers in non-heme diiron enzymes: carboxylate shifts in diiron(II) complexes supported by sterically hindered carboxylate ligands. Inorg Chem (2002) 1.24
Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex. J Am Chem Soc (2010) 1.23
Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. Chem Biol (2004) 1.22
Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors. Annu Rev Biochem (2011) 1.21
Metal-based turn-on fluorescent probes for sensing nitric oxide. Acc Chem Res (2007) 1.20
Product bound structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): protein motion in the alpha-subunit. J Am Chem Soc (2005) 1.19
RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase. J Biol Chem (2005) 1.19
Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. J Am Chem Soc (2006) 1.18
Soluble methane monooxygenase: activation of dioxygen and methane. Curr Opin Chem Biol (2002) 1.18
Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting. Dalton Trans (2009) 1.17
Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes. J Am Chem Soc (2006) 1.16
Esterase-activated two-fluorophore system for ratiometric sensing of biological zinc(II). Inorg Chem (2005) 1.15
QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). J Am Chem Soc (2005) 1.14
Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn2+ sensors. J Am Chem Soc (2009) 1.14
Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. J Am Chem Soc (2008) 1.14
Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc (2004) 1.14
Meeting of the minds: metalloneurochemistry. Proc Natl Acad Sci U S A (2003) 1.14
Monofunctional and higher-valent platinum anticancer agents. Inorg Chem (2013) 1.13
Redox state-dependent interaction of HMGB1 and cisplatin-modified DNA. Biochemistry (2011) 1.13
Characterization of iron dinitrosyl species formed in the reaction of nitric oxide with a biological Rieske center. J Am Chem Soc (2010) 1.12
Control of substrate access to the active site in methane monooxygenase. Nature (2013) 1.12
Synthetic methods for the preparation of platinum anticancer complexes. Chem Rev (2013) 1.11
Selective labeling of extracellular proteins containing polyhistidine sequences by a fluorescein-nitrilotriacetic acid conjugate. J Am Chem Soc (2006) 1.10
Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols. J Am Chem Soc (2008) 1.10
Substrate hydroxylation in methane monooxygenase: quantitative modeling via mixed quantum mechanics/molecular mechanics techniques. J Am Chem Soc (2005) 1.10
Understanding and improving platinum anticancer drugs--phenanthriplatin. Anticancer Res (2014) 1.10
Reversible dioxygen binding to hemerythrin. J Am Chem Soc (2003) 1.09
Characterization of a peroxodiiron(III) intermediate in the T201S variant of toluene/o-xylene monooxygenase hydroxylase from Pseudomonas sp. OX1. J Am Chem Soc (2009) 1.09
X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior. J Am Chem Soc (2006) 1.09
Reactions of methane monooxygenase intermediate Q with derivatized methanes. J Am Chem Soc (2002) 1.08
Visualization of nitric oxide production in the mouse main olfactory bulb by a cell-trappable copper(II) fluorescent probe. Proc Natl Acad Sci U S A (2010) 1.08
Synthetic analogue of the [Fe(2)(mu-OH)(2)(mu-O(2)CR)](3+) core of soluble methane monooxygenase hydroxylase via synthesis and dioxygen reactivity of carboxylate-bridged diiron(II) complexes. Inorg Chem (2002) 1.08
Nature of full-length HMGB1 binding to cisplatin-modified DNA. Biochemistry (2003) 1.08
Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links. Biochemistry (2009) 1.08
A novel two-fluorophore approach to ratiometric sensing of Zn(2+). J Am Chem Soc (2003) 1.07
Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine? J Am Chem Soc (2003) 1.06
Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorg Chem (2004) 1.06
Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework. J Am Chem Soc (2011) 1.06
Synthesis of diethynyltriptycene-linked dipyridyl ligands. Org Lett (2005) 1.06
Redox activation of metal-based prodrugs as a strategy for drug delivery. Adv Drug Deliv Rev (2012) 1.06
Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. Inorg Chem (2006) 1.05