Published in J Am Chem Soc on October 30, 2007
Conversion of fatty aldehydes to alka(e)nes and formate by a cyanobacterial aldehyde decarbonylase: cryptic redox by an unusual dimetal oxygenase. J Am Chem Soc (2011) 1.54
Structural consequences of effector protein complex formation in a diiron hydroxylase. Proc Natl Acad Sci U S A (2008) 1.47
A long-lived, substrate-hydroxylating peroxodiiron(III/III) intermediate in the amine oxygenase, AurF, from Streptomyces thioluteus. J Am Chem Soc (2009) 1.36
Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes. Chem Soc Rev (2010) 1.33
Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. J Am Chem Soc (2010) 1.24
Cyanobacterial alkane biosynthesis further expands the catalytic repertoire of the ferritin-like 'di-iron-carboxylate' proteins. Curr Opin Chem Biol (2011) 1.19
Characterization of a peroxodiiron(III) intermediate in the T201S variant of toluene/o-xylene monooxygenase hydroxylase from Pseudomonas sp. OX1. J Am Chem Soc (2009) 1.09
Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase. Biochemistry (2007) 1.03
Substrate-triggered addition of dioxygen to the diferrous cofactor of aldehyde-deformylating oxygenase to form a diferric-peroxide intermediate. J Am Chem Soc (2013) 1.01
Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites. J Inorg Biochem (2011) 1.01
Substrate-triggered activation of a synthetic [Fe2(μ-O)2] diamond core for C-H bond cleavage. J Am Chem Soc (2011) 1.00
Active site threonine facilitates proton transfer during dioxygen activation at the diiron center of toluene/o-xylene monooxygenase hydroxylase. J Am Chem Soc (2010) 0.96
Mössbauer, electron paramagnetic resonance, and density functional theory studies of synthetic S = 1/2 Fe(III)-O-Fe(IV)═O complexes. Superexchange-mediated spin transition at the Fe(IV)═O site. Inorg Chem (2010) 0.94
Kinetic characterization of the soluble butane monooxygenase from Thauera butanivorans, formerly 'Pseudomonas butanovora'. Microbiology (2009) 0.93
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An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway. J Am Chem Soc (2015) 0.88
Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV. J Am Chem Soc (2009) 0.87
Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1. Biochemistry (2011) 0.87
The manganese/iron-carboxylate proteins: what is what, where are they, and what can the sequences tell us? J Biol Inorg Chem (2010) 0.87
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Divergent mechanisms of iron-containing enzymes for hydrocarbon biosynthesis. J Biol Inorg Chem (2016) 0.86
Structure and mechanism of the diiron benzoyl-coenzyme A epoxidase BoxB. J Biol Chem (2011) 0.85
Insights into the different dioxygen activation pathways of methane and toluene monooxygenase hydroxylases. J Am Chem Soc (2011) 0.85
Hydrogen-bonding effects on the reactivity of [X-Fe(III)-O-Fe(IV)═O] (X = OH, F) complexes toward C-H bond cleavage. Inorg Chem (2013) 0.84
Characterization of a synthetic peroxodiiron(III) protein model complex by nuclear resonance vibrational spectroscopy. Chem Commun (Camb) (2011) 0.83
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The catalase activity of diiron adenine deaminase. Protein Sci (2011) 0.76
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Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. J Am Chem Soc (2007) 1.50
Intermediates in the oxygenation of a nonheme diiron(II) complex, including the first evidence for a bound superoxo species. Proc Natl Acad Sci U S A (2005) 1.43
X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase. Biochemistry (2006) 1.38
Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethers. J Am Chem Soc (2005) 1.38
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(Mu-1,2-peroxo)diiron(III/III) complex as a precursor to the diiron(III/IV) intermediate X in the assembly of the iron-radical cofactor of ribonucleotide reductase from mouse. Biochemistry (2007) 1.33
Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. J Am Chem Soc (2006) 1.32
Combined participation of hydroxylase active site residues and effector protein binding in a para to ortho modulation of toluene 4-monooxygenase regiospecificity. Biochemistry (2002) 1.29
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Phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas stutzeri OX1: interplay between two enzymes. Appl Environ Microbiol (2004) 1.26
Product bound structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): protein motion in the alpha-subunit. J Am Chem Soc (2005) 1.19
Structural and spectroscopic characterization of (mu-hydroxo or mu-oxo)(mu-peroxo)diiron(III) complexes: models for peroxo intermediates of non-heme diiron proteins. J Am Chem Soc (2005) 1.18
Aerobic degradation of tetrachloroethylene by toluene-o-xylene monooxygenase of Pseudomonas stutzeri OX1. Nat Biotechnol (2000) 1.16
Component interactions in the soluble methane monooxygenase system from Methylococcus capsulatus (Bath). Biochemistry (1999) 1.16
X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior. J Am Chem Soc (2006) 1.09
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X-ray crystal structures of reduced rubrerythrin and its azide adduct: a structure-based mechanism for a non-heme diiron peroxidase. J Am Chem Soc (2002) 1.08
Insight into the mechanism of aromatic hydroxylation by toluene 4-monooxygenase by use of specifically deuterated toluene and p-xylene. Proc Natl Acad Sci U S A (2003) 1.07
Rational reprogramming of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase. J Am Chem Soc (2001) 1.05
Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase. Biochemistry (2007) 1.03
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Biochemical, Mössbauer, and EPR studies of the diiron cluster of phenol hydroxylase from Pseudomonas sp. strain CF 600. Biochemistry (2002) 0.96
Regioselective arene hydroxylation mediated by a (mu-peroxo)diiron(III) complex: a functional model for toluene monooxygenase. J Am Chem Soc (2007) 0.96
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Dioxygen-initiated oxidation of heteroatomic substrates incorporated into ancillary pyridine ligands of carboxylate-rich diiron(II) complexes. Inorg Chem (2006) 0.91
Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexes. Inorg Chem (2006) 0.84
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Generation and characterization of [(P)M-(X)-Co(TMPA)]n+ assemblies; P = Porphyrinate, M = FeIII and CoIII, X = O2-, OH-, O2(2-), and TMPA = tris(2-pyridylmethyl)amine. Inorg Chem (2007) 0.78
Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov (2005) 9.47
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Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc Natl Acad Sci U S A (2008) 3.62
Direct cellular responses to platinum-induced DNA damage. Chem Rev (2007) 3.42
Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(IV) anticancer drug design. J Am Chem Soc (2007) 2.82
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (2013) 2.61
Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. J Am Chem Soc (2008) 2.40
Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res (2006) 2.37
Visualization of nitric oxide in living cells by a copper-based fluorescent probe. Nat Chem Biol (2006) 2.33
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A (2010) 2.21
Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. J Am Chem Soc (2009) 2.16
Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc Natl Acad Sci U S A (2011) 2.16
Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. Acc Chem Res (2009) 2.07
Dioxygen activation in soluble methane monooxygenase. Acc Chem Res (2011) 2.07
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes Dev (2010) 1.95
Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins. Acc Chem Res (2006) 1.93
Mechanistic studies on the hydroxylation of methane by methane monooxygenase. Chem Rev (2003) 1.89
New metal complexes as potential therapeutics. Curr Opin Chem Biol (2003) 1.89
Inhibition of transcription by platinum antitumor compounds. Metallomics (2009) 1.88
Chloroplast monothiol glutaredoxins as scaffold proteins for the assembly and delivery of [2Fe-2S] clusters. EMBO J (2008) 1.81
A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. Cancer Res (2010) 1.79
Tools and tactics for the optical detection of mercuric ion. Chem Rev (2008) 1.77
Formation and properties of [4Fe-4S] clusters on the IscU scaffold protein. Biochemistry (2007) 1.76
The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry (2009) 1.75
Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem (2009) 1.71
MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters. Biochemistry (2007) 1.68
Synthesis, characterization, and cytotoxicity of a series of estrogen-tethered platinum(IV) complexes. Chem Biol (2004) 1.66
Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster. Proc Natl Acad Sci U S A (2003) 1.63
cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proc Natl Acad Sci U S A (2008) 1.62
Imaging mobile zinc in biology. Curr Opin Chem Biol (2010) 1.57
Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing. Proc Natl Acad Sci U S A (2007) 1.53
In vitro activation of apo-aconitase using a [4Fe-4S] cluster-loaded form of the IscU [Fe-S] cluster scaffolding protein. Biochemistry (2007) 1.51
Consequences of cisplatin binding on nucleosome structure and dynamics. Chem Biol (2010) 1.51
Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy. Inorg Chem (2006) 1.50
Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. J Am Chem Soc (2007) 1.50
Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages. Proc Natl Acad Sci U S A (2008) 1.49
Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile. Proc Natl Acad Sci U S A (2012) 1.48
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature. Bioconjug Chem (2007) 1.46
Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols. J Am Chem Soc (2012) 1.46
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proc Natl Acad Sci U S A (2002) 1.45
Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases. Acc Chem Res (2007) 1.43
Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate. Proc Natl Acad Sci U S A (2009) 1.43
Bacterial nitric-oxide synthases operate without a dedicated redox partner. J Biol Chem (2008) 1.41
The interface of inorganic chemistry and biology. J Am Chem Soc (2010) 1.41
Coordination of adenosylmethionine to a unique iron site of the [4Fe-4S] of pyruvate formate-lyase activating enzyme: a Mössbauer spectroscopic study. J Am Chem Soc (2002) 1.41
Characterization of the cofactor composition of Escherichia coli biotin synthase. Biochemistry (2004) 1.40
X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc Natl Acad Sci U S A (2010) 1.39
X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase. Biochemistry (2006) 1.38
Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethers. J Am Chem Soc (2005) 1.38
Dioxygen activation in methane monooxygenase: a theoretical study. J Am Chem Soc (2004) 1.38
Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis. J Biol Chem (2004) 1.36
Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand. Inorg Chem (2003) 1.35
Membrane-permeable and -impermeable sensors of the Zinpyr family and their application to imaging of hippocampal zinc in vivo. Chem Biol (2004) 1.33
(Mu-1,2-peroxo)diiron(III/III) complex as a precursor to the diiron(III/IV) intermediate X in the assembly of the iron-radical cofactor of ribonucleotide reductase from mouse. Biochemistry (2007) 1.33
Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes. Chem Soc Rev (2010) 1.33
Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. J Am Chem Soc (2006) 1.32
Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proc Natl Acad Sci U S A (2013) 1.30
Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450. Proc Natl Acad Sci U S A (2003) 1.30
ZP4, an improved neuronal Zn2+ sensor of the Zinpyr family. J Am Chem Soc (2003) 1.29
Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron (2011) 1.29
New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensor. J Am Chem Soc (2008) 1.28
A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proc Natl Acad Sci U S A (2004) 1.27
A proposed role for the Azotobacter vinelandii NfuA protein as an intermediate iron-sulfur cluster carrier. J Biol Chem (2008) 1.27
A flavodiiron protein and high molecular weight rubredoxin from Moorella thermoacetica with nitric oxide reductase activity. Biochemistry (2003) 1.27
Nucleotide excision repair from site-specifically platinum-modified nucleosomes. Biochemistry (2003) 1.27
Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathway. Biochemistry (2009) 1.26
Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate Q. J Am Chem Soc (2002) 1.25
Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis. Proc Natl Acad Sci U S A (2011) 1.25
Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. J Am Chem Soc (2010) 1.24
Modeling dioxygen-activating centers in non-heme diiron enzymes: carboxylate shifts in diiron(II) complexes supported by sterically hindered carboxylate ligands. Inorg Chem (2002) 1.24
Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex. J Am Chem Soc (2010) 1.23
Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. Chem Biol (2004) 1.22
NifS-mediated assembly of [4Fe-4S] clusters in the N- and C-terminal domains of the NifU scaffold protein. Biochemistry (2005) 1.21
Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors. Annu Rev Biochem (2011) 1.21
Metal-based turn-on fluorescent probes for sensing nitric oxide. Acc Chem Res (2007) 1.20
Product bound structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): protein motion in the alpha-subunit. J Am Chem Soc (2005) 1.19
RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase. J Biol Chem (2005) 1.19
Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. J Am Chem Soc (2006) 1.18
Stoichiometric production of hydrogen peroxide and parallel formation of ferric multimers through decay of the diferric-peroxo complex, the first detectable intermediate in ferritin mineralization. Biochemistry (2002) 1.18
Soluble methane monooxygenase: activation of dioxygen and methane. Curr Opin Chem Biol (2002) 1.18
A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. J Am Chem Soc (2003) 1.18
Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting. Dalton Trans (2009) 1.17
Native Escherichia coli SufA, coexpressed with SufBCDSE, purifies as a [2Fe-2S] protein and acts as an Fe-S transporter to Fe-S target enzymes. J Am Chem Soc (2009) 1.16
Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes. J Am Chem Soc (2006) 1.16
Role of the [2Fe-2S] cluster in recombinant Escherichia coli biotin synthase. Biochemistry (2004) 1.15
Esterase-activated two-fluorophore system for ratiometric sensing of biological zinc(II). Inorg Chem (2005) 1.15
Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. J Am Chem Soc (2008) 1.14
Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn2+ sensors. J Am Chem Soc (2009) 1.14
Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc (2004) 1.14