Published in J Mol Evol on September 01, 2003
DNA replication origins in the Schizosaccharomyces pombe genome. Proc Natl Acad Sci U S A (2004) 1.78
Transcription-coupled and splicing-coupled strand asymmetries in eukaryotic genomes. Nucleic Acids Res (2004) 1.38
Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis. BMC Mol Biol (2007) 1.17
DNA asymmetric strand bias affects the amino acid composition of mitochondrial proteins. DNA Res (2007) 0.93
GraphDNA: a Java program for graphical display of DNA composition analyses. BMC Bioinformatics (2007) 0.85
Strand bias structure in mouse DNA gives a glimpse of how chromatin structure affects gene expression. BMC Genomics (2008) 0.79
Genomic DNA from animals shows contrasting strand bias in large and small subsequences. BMC Genomics (2008) 0.78
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
The complete genome sequence of Escherichia coli K-12. Science (1997) 84.27
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature (2000) 70.33
Genome sequence of the nematode C. elegans: a platform for investigating biology. Science (1998) 61.48
Life with 6000 genes. Science (1996) 41.51
Genome sequence of the human malaria parasite Plasmodium falciparum. Nature (2002) 37.89
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature (1997) 19.08
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Replication dynamics of the yeast genome. Science (2001) 7.56
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi. Nature (2001) 7.53
Asymmetric substitution patterns in the two DNA strands of bacteria. Mol Biol Evol (1996) 7.18
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science (2001) 6.06
Analyzing genomes with cumulative skew diagrams. Nucleic Acids Res (1998) 3.71
Transcription-associated mutational asymmetry in mammalian evolution. Nat Genet (2003) 3.52
A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. Biochemistry (1990) 3.51
Base composition skews, replication orientation, and gene orientation in 12 prokaryote genomes. J Mol Evol (1998) 2.98
Paradoxes of eukaryotic DNA replication: MCM proteins and the random completion problem. Bioessays (2003) 2.54
Asymmetric substitution patterns: a review of possible underlying mutational or selective mechanisms. Gene (1999) 2.40
Asymmetrical directional mutation pressure in the mitochondrial genome of mammals. Mol Biol Evol (1998) 2.06
Universal replication biases in bacteria. Mol Microbiol (1999) 1.89
Strand compositional asymmetry in bacterial and large viral genomes. Proc Natl Acad Sci U S A (1998) 1.84
A simple vectorial representation of DNA sequences for the detection of replication origins in bacteria. Biochimie (1996) 1.73
Biological asymmetries and the fidelity of eukaryotic DNA replication. Bioessays (1992) 1.73
Initiation at closely spaced replication origins in a yeast chromosome. Science (1993) 1.67
Intrastrand parity rules of DNA base composition and usage biases of synonymous codons. J Mol Evol (1995) 1.65
Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosome. Proc Natl Acad Sci U S A (1998) 1.62
The contributions of replication orientation, gene direction, and signal sequences to base-composition asymmetries in bacterial genomes. J Mol Evol (2000) 1.58
Inequality in mutation rates of the two strands of DNA. Nature (1987) 1.47
Deamination as the basis of strand-asymmetric evolution in transcribed Escherichia coli sequences. Mol Biol Evol (2001) 1.47
Analyzing DNA strand compositional asymmetry to identify candidate replication origins of Borrelia burgdorferi linear and circular plasmids. Genome Res (2000) 1.31
Strand-specific compositional asymmetries in double-stranded DNA viruses. Virus Res (1999) 1.23
Properties of a general model of DNA evolution under no-strand-bias conditions. J Mol Evol (1995) 1.22
Skew of mononucleotide frequencies, relative abundance of dinucleotides, and DNA strand asymmetry. J Mol Evol (2001) 1.12
Ongoing evolution of strand composition in bacterial genomes. Mol Biol Evol (2001) 1.11
Identification of a putative chromosomal replication origin from Helicobacter pylori and its interaction with the initiator protein DnaA. Nucleic Acids Res (2001) 1.08
Asymmetry of frameshift mutagenesis during leading and lagging-strand replication in Escherichia coli. Mutat Res (2002) 1.05
Strand symmetry around the beta-globin origin of replication in primates. Mol Biol Evol (2000) 1.00
Transcription-induced cytosine-to-thymine mutations are not dependent on sequence context of the target cytosine. J Bacteriol (2001) 1.00
DNA asymmetry and the replicational mutational pressure. J Appl Genet (2001) 0.97
Evolution of DNA base composition under no-strand-bias conditions when the substitution rates are not constant. Mol Biol Evol (1999) 0.96
Strand symmetry of mutation rates in the beta-globin region. J Mol Evol (1991) 0.94
Is there replication-associated mutational pressure in the Saccharomyces cerevisiae genome? J Theor Biol (2000) 0.90
Replication error rates for G.dGTP, T.dGTP, and A.dGTP mispairs and evidence for differential proofreading by leading and lagging strand DNA replication complexes in human cells. J Biol Chem (1995) 0.84
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol (2008) 3.36
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
Identification of cell cycle-regulated genes in fission yeast. Mol Biol Cell (2004) 2.29
InterDom: a database of putative interacting protein domains for validating predicted protein interactions and complexes. Nucleic Acids Res (2003) 1.94
Prediction of yeast protein-protein interaction network: insights from the Gene Ontology and annotations. Nucleic Acids Res (2006) 1.93
In vivo viscoelastic properties of the brain in normal pressure hydrocephalus. NMR Biomed (2010) 1.67
Xanthomonas campestris cell-cell communication involves a putative nucleotide receptor protein Clp and a hierarchical signalling network. Mol Microbiol (2007) 1.53
Genome scale analysis of diffusible signal factor regulon in Xanthomonas campestris pv. campestris: identification of novel cell-cell communication-dependent genes and functions. Mol Microbiol (2006) 1.41
Identification of Arabidopsis rat mutants. Plant Physiol (2003) 1.32
RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics (2011) 1.27
Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers. Proc Natl Acad Sci U S A (2012) 1.22
Alteration of brain viscoelasticity after shunt treatment in normal pressure hydrocephalus. Neuroradiology (2011) 1.21
Genetic uniformity characterizes the invasive spread of water hyacinth (Eichhornia crassipes), a clonal aquatic plant. Mol Ecol (2010) 1.20
Targeting activated Akt with GDC-0068, a novel selective Akt inhibitor that is efficacious in multiple tumor models. Clin Cancer Res (2013) 1.18
Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Res (2002) 1.15
An initial strategy for comparing proteins at the domain architecture level. Bioinformatics (2006) 1.14
Sequencing angiosperm plastid genomes made easy: a complete set of universal primers and a case study on the phylogeny of saxifragales. Genome Biol Evol (2013) 1.13
Nuclear and chloroplast DNA phylogeography reveal two refuge areas with asymmetrical gene flow in a temperate walnut tree from East Asia. New Phytol (2010) 1.09
Improving the measurement of semantic similarity between gene ontology terms and gene products: insights from an edge- and IC-based hybrid method. PLoS One (2013) 1.08
A nearly neutral model of biodiversity. Ecology (2008) 1.03
BPhyOG: an interactive server for genome-wide inference of bacterial phylogenies based on overlapping genes. BMC Bioinformatics (2007) 1.00
Female reproductive success decreases with display size in monkshood, Aconitum kusnezoffii (Ranunculaceae). Ann Bot (2009) 0.99
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors. J Med Chem (2012) 0.96
Flowering phenology and wind-pollination efficacy of heterodichogamous Juglans mandshurica (Juglandaceae). Ann Bot (2006) 0.95
Overlapping genes as rare genomic markers: the phylogeny of gamma-Proteobacteria as a case study. Trends Genet (2006) 0.94
The excess of 5' introns in eukaryotic genomes. Nucleic Acids Res (2005) 0.94
Adaptive significance of flexistyly in Alpinia blepharocalyx (Zingiberaceae): a hand-pollination experiment. Ann Bot (2007) 0.93
Overexpression of several Arabidopsis histone genes increases agrobacterium-mediated transformation and transgene expression in plants. Plant Cell (2009) 0.92
Excess of microRNAs in large and very 5' biased introns. Biochem Biophys Res Commun (2008) 0.91
Development of microsatellite loci for Blastophaga javana (Agaonidae), the pollinating wasp of Ficus hirta (Moraceae). Am J Bot (2011) 0.91
SPIDer: Saccharomyces protein-protein interaction database. BMC Bioinformatics (2006) 0.90
Demographic trade-offs in a neutral model explain death-rate--abundance-rank relationship. Ecology (2009) 0.89
Mating patterns and pollen dispersal in a heterodichogamous tree, Juglans mandshurica (Juglandaceae). New Phytol (2007) 0.89
Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res (2011) 0.87
Adaptive expression responses in the Pol-gamma null strain of S. pombe depleted of mitochondrial genome. BMC Genomics (2007) 0.86
A phylogenomic analysis of Escherichia coli / Shigella group: implications of genomic features associated with pathogenicity and ecological adaptation. BMC Evol Biol (2012) 0.85
Geographic variation in the structure of oak hybrid zones provides insights into the dynamics of speciation. Mol Ecol (2011) 0.85
Donald's Ideotype and growth redundancy: a pot experimental test using an old and a modern spring wheat cultivar. PLoS One (2013) 0.85
Life history trait differentiation and local adaptation in invasive populations of Ambrosia artemisiifolia in China. Oecologia (2014) 0.84
Autophagy, an Achilles' heel AKTing against cancer? Autophagy (2009) 0.83
Variation in floral sex allocation and reproductive success in sequentially flowering inflorescence of Corydalis remota var. lineariloba (Fumariaceae). J Integr Plant Biol (2009) 0.83
Increased maleness at flowering stage and femaleness at fruiting stage with size in an andromonoecious perennial, Veratrum nigrum. J Integr Plant Biol (2008) 0.82
Tetra: an improved program for population genetic analysis of allotetraploid microsatellite data. Mol Ecol Resour (2008) 0.82
Exploring species limits in two closely related Chinese oaks. PLoS One (2010) 0.81
Influence of harvest time on fuel characteristics of five potential energy crops in northern China. Bioresour Technol (2007) 0.80
Genome-wide inference of protein interaction sites: lessons from the yeast high-quality negative protein-protein interaction dataset. Nucleic Acids Res (2008) 0.80
Purification, crystallization and preliminary X-ray analysis of the DndE protein from Salmonella enterica serovar Cerro 87, which is involved in DNA phosphorothioation. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.80
The incidence and pattern of copollinator diversification in dioecious and monoecious figs. Evolution (2015) 0.80
Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. PLoS One (2011) 0.80
The role of late-acting self-incompatibility and early-acting inbreeding depression in governing female fertility in monkshood, Aconitum kusnezoffii. PLoS One (2012) 0.79
The distribution pattern of genetic variation in the transcript isoforms of the alternatively spliced protein-coding genes in the human genome. Mol Biosyst (2015) 0.79
Biotransformation of 4(20),11-taxadienes by cell suspension cultures of Platycodon grandiflorum. J Asian Nat Prod Res (2003) 0.79
The properties of hub proteins in a yeast-aggregated cell cycle network and its phase sub-networks. Proteomics (2009) 0.79
Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside. Mol Microbiol (2013) 0.79
Yeast protein-protein interaction binding sites: prediction from the motif-motif, motif-domain and domain-domain levels. Mol Biosyst (2010) 0.79
Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation. PLoS One (2012) 0.79
[Comparative study of four alkaloids contents and antitussive activities of Stemona tuberosa from different habitats of Guangxi Province]. Zhong Yao Cai (2014) 0.78
A new flavanone from the aerial parts of Penthorum chinense. Nat Prod Res (2014) 0.78
Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility. Biochem Biophys Res Commun (2011) 0.78
No evolutionary shift in the mating system of north American Ambrosia artemisiifolia (Asteraceae) following its introduction to China. PLoS One (2012) 0.77
Molecular dynamics simulations of the enhanced recovery of confined methane with carbon dioxide. Phys Chem Chem Phys (2015) 0.77
The evolutionary relationship of the domain architectures in the RhoGEF-containing proteins. Genomics Proteomics Bioinformatics (2005) 0.77
mTOR kinase inhibitor potentiates apoptosis of PI3K and MEK inhibitors in diagnostically defined subpopulations. Cancer Lett (2012) 0.77
Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo. Oncol Rep (2013) 0.77
Adsorption of p-nitrophenol from aqueous solutions onto activated carbon fiber. J Hazard Mater (2006) 0.76
The hepatoprotective effect of aqueous extracts of Penthorum chinense Pursh against acute alcohol-induced liver injury is associated with ameliorating hepatic steatosis and reducing oxidative stress. Food Funct (2015) 0.76
Promiscuous domains: facilitating stability of the yeast protein-protein interaction network. Mol Biosyst (2011) 0.76
Evolutionary dynamics of overlapped genes in Salmonella. PLoS One (2013) 0.75
[TcpC induces apoptosis of human vascular endothelial cells and its mechanisms]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2013) 0.75
Synthesis and evaluation of cytotoxic effects of novel α-methylenelactone tetracyclic diterpenoids. Bioorg Med Chem Lett (2012) 0.75
[Research progress of the biological characteristics of IkappaB kinase and its inhibitors]. Yao Xue Xue Bao (2011) 0.75
[DNA barcoding and its utility in commonly-used medicinal snakes]. Zhongguo Zhong Yao Za Zhi (2015) 0.75
[Reevaluate the effect of G-480 point mutation that determines the neurovirulence of type I vaccine polioviruses]. Bing Du Xue Bao (2007) 0.75
Feasibility study of enforcing immunization certificate check before primary school or kindergarten enrollment in Guizhou Province, China. Biomed Environ Sci (2007) 0.75
Wrinkled petals and stamens 1, is required for the morphogenesis of petals and stamens in Lotus japonicus. Cell Res (2006) 0.75
Effect of input pathways and altitudes on spatial distribution of polycyclic aromatic hydrocarbons in background soils, the Tibetan Plateau. Environ Sci Pollut Res Int (2015) 0.75
Dispersal limitation favors more fecund species in the presence of fitness-equalizing demographic trade-offs. Am Nat (2015) 0.75
[An analysis about the safe range of thickness of the residual corneal stroma bed after LASIK]. Zhonghua Yan Ke Za Zhi (2004) 0.75
Glycosylation of ent-kaurene derivatives and an evaluation of their cytotoxic activities. Chin J Nat Med (2013) 0.75
Hierarchical Map of Orthologous Genomic Regions Reconstructed from Two Closely Related Genomes: Cucumber Case Study. Plant Genome (2016) 0.75
[Classification and synthesis of ubiquitin-proteasome inhibitor]. Yao Xue Xue Bao (2009) 0.75
Self-assembly of fluorescent carbon dots in a N,N-dimethylmethanamide solution via Schiff base reaction. Nanoscale (2015) 0.75
A fast sequence assembly method based on compressed data structures. Conf Proc IEEE Eng Med Biol Soc (2014) 0.75
[Research on LC-based spectral imaging system for visible band]. Guang Pu Xue Yu Guang Pu Fen Xi (2011) 0.75