Published in J Mammary Gland Biol Neoplasia on April 01, 2003
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer. Breast Cancer Res (2010) 3.53
Hormonal and local control of mammary branching morphogenesis. Differentiation (2006) 2.60
Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis. Breast Cancer Res (2005) 2.46
Involvement of insulin receptor substrate 2 in mammary tumor metastasis. Mol Cell Biol (2004) 1.55
The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells. Mol Endocrinol (2005) 1.52
Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer. Nucl Recept Signal (2007) 1.37
The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium. Breast Cancer Res (2006) 1.35
Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer. Breast Cancer Res (2005) 1.23
The biology of progesterone receptor in the normal mammary gland and in breast cancer. Mol Cell Endocrinol (2011) 1.19
Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis. Mol Cell Biol (2006) 1.19
Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Proc Natl Acad Sci U S A (2010) 1.14
Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy. Nucleic Acids Res (2011) 1.09
DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations. Cancer Epidemiol Biomarkers Prev (2009) 1.04
The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention. Mol Endocrinol (2010) 1.01
Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1). J Biol Chem (2011) 1.00
Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells. Proc Natl Acad Sci U S A (2009) 0.97
Progesterone receptor status and Ki-67 index may predict early relapse in luminal B/HER2 negative breast cancer patients: a retrospective study. PLoS One (2014) 0.93
Inhibiting gene expression with locked nucleic acids (LNAs) that target chromosomal DNA. Biochemistry (2007) 0.93
Immortalization of epithelial progenitor cells mediated by resveratrol. Oncogene (2007) 0.92
Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells. Mol Cell Biol (2012) 0.90
Social isolation reduces mammary development, tumor incidence, and expression of epigenetic regulators in wild-type and p53-heterozygotic mice. Cancer Prev Res (Phila) (2010) 0.87
Regulation of progesterone receptor signaling by BRCA1 in mammary cancer. Nucl Recept Signal (2006) 0.86
Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Mol Endocrinol (2014) 0.84
Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures. BMC Cancer (2006) 0.84
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters. Int J Cancer (2014) 0.84
Association of cellular and molecular responses in the rat mammary gland to 17β-estradiol with susceptibility to mammary cancer. BMC Cancer (2013) 0.82
Association of progesterone receptor polymorphism with idiopathic recurrent pregnancy loss in Taiwanese Han population. J Assist Reprod Genet (2010) 0.81
Integrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone. BMC Cancer (2014) 0.78
Deep sequencing reveals new aspects of progesterone receptor signaling in breast cancer cells. PLoS One (2014) 0.77
Hormone Signaling Requirements for the Conversion of Non-Mammary Mouse Cells to Mammary Cell Fate(s) in Vivo. J Mammary Gland Biol Neoplasia (2015) 0.75
The Effect of Menopausal Hormone Therapies on Breast Cancer: Avoiding the Risk. Endocrinol Metab Clin North Am (2015) 0.75
Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A (2003) 3.30
Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis (2005) 2.67
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice. Cancer Res (2008) 2.15
Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod (2010) 2.12
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet (2006) 2.11
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
Reproductive functions of progesterone receptors. Recent Prog Horm Res (2002) 1.82
WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J (2010) 1.79
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet (2007) 1.79
BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest (2013) 1.70
The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol (2009) 1.67
A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol (2002) 1.61
Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology (2005) 1.59
Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet (2013) 1.56
NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod (2012) 1.52
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
A repressive role for prohibitin in estrogen signaling. Mol Endocrinol (2007) 1.40
Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol (2002) 1.37
In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol (2008) 1.34
Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms. Steroids (2003) 1.34
Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology (2008) 1.33
Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A (2009) 1.28
Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice. Mol Cell Biol (2008) 1.24
Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development (2008) 1.22
Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus. Mol Endocrinol (2012) 1.22
Mouse models of implantation. Trends Endocrinol Metab (2007) 1.20
A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med (2012) 1.20
Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells. Cancer Res (2009) 1.19
Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J (2011) 1.19
Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids (2003) 1.19
The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology (2007) 1.15
Maternal heparin-binding-EGF deficiency limits pregnancy success in mice. Proc Natl Acad Sci U S A (2007) 1.15
Stromal progesterone receptors mediate induction of Indian Hedgehog (IHH) in uterine epithelium and its downstream targets in uterine stroma. Endocrinology (2009) 1.14
Signal transducer and activator of transcription-3 (Stat3) plays a critical role in implantation via progesterone receptor in uterus. FASEB J (2013) 1.14
WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development. Biol Reprod (2010) 1.12
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development (2013) 1.11
Revealing progesterone's role in uterine and mammary gland biology: insights from the mouse. Semin Reprod Med (2005) 1.07
Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human. Nucl Recept Signal (2007) 1.06
Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology (2005) 1.05
A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis (2010) 1.05
CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod (2012) 1.04
Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod (2010) 1.03
Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet (2013) 1.02
Epithelial-stromal interaction and progesterone receptors in the mouse uterus. Semin Reprod Med (2010) 1.01
VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Mol Med (2013) 1.00
Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Mol Endocrinol (2013) 1.00
Intact progesterone receptors are essential to counteract the proliferative effect of estradiol in a genetically engineered mouse model of endometriosis. Fertil Steril (2004) 0.99
Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology (2012) 0.99
Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod (2010) 0.98
Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability. Eur J Immunol (2012) 0.98
Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Mol Endocrinol (2010) 0.97
Connective tissue growth factor is required for normal follicle development and ovulation. Mol Endocrinol (2011) 0.96
The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression. Endocrinology (2009) 0.96
Liver receptor homolog-1 is essential for pregnancy. Nat Med (2013) 0.95
From the ranks of mammary progesterone mediators, RANKL takes the spotlight. Mol Cell Endocrinol (2011) 0.94
Bone growth and turnover in progesterone receptor knockout mice. Endocrinology (2008) 0.93
The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action. J Oncol (2009) 0.91
Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell (2012) 0.91
Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics. Breast Cancer Res (2002) 0.90
Progesterone signaling inhibits cervical carcinogenesis in mice. Am J Pathol (2013) 0.90
Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs. Mol Endocrinol (2013) 0.90
Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology (2011) 0.89
Targeting reverse tetracycline-dependent transactivator to murine mammary epithelial cells that express the progesterone receptor. Genesis (2007) 0.86
Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. Cancer Res (2013) 0.86
GATA2 is expressed at critical times in the mouse uterus during pregnancy. Gene Expr Patterns (2012) 0.86
Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest (2015) 0.86
ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod (2009) 0.85
Progesterone regulation of reproductive function through functionally distinct progesterone receptor isoforms. Rev Endocr Metab Disord (2002) 0.85
The pattern of beta-catenin responsiveness within the mammary gland is regulated by progesterone receptor. Development (2007) 0.85
Alterations in Wnt-β-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression. J Pathol (2013) 0.85
Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol (2006) 0.85
Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterus. FASEB J (2013) 0.84
β-Catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition. J Pathol (2013) 0.84
Generation of a mouse for conditional excision of progesterone receptor. Genesis (2006) 0.84
Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol (2012) 0.84
Stem cells: Cues from steroid hormones. Nature (2010) 0.83
Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology (2012) 0.83
Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development. Mol Endocrinol (2004) 0.82
Role of the progesterone receptor (PR) in susceptibility of mouse mammary gland to 7,12-dimethylbenz[a]anthracene-induced hormone-independent preneoplastic lesions in vitro. Cancer Lett (2002) 0.82
Functional role of progestin and the progesterone receptor in the suppression of spermatogenesis in rodents. Andrology (2013) 0.81
Targeting iCre expression to murine progesterone receptor cell-lineages using bacterial artificial chromosome transgenesis. Genesis (2006) 0.81
A mouse model for endometrioid ovarian cancer arising from the distal oviduct. Int J Cancer (2014) 0.81
A mouse transgenic approach to induce β-catenin signaling in a temporally controlled manner. Transgenic Res (2010) 0.80
Activated AKT pathway promotes establishment of endometriosis. Endocrinology (2014) 0.80
Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice. Biol Reprod (2014) 0.80
Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice. Mol Cell Endocrinol (2011) 0.80
Progesterone-action in the murine uterus and mammary gland requires steroid receptor coactivator 2: relevance to the human. Front Biosci (2007) 0.80
Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells. J Cell Sci (2013) 0.78
A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod (2014) 0.78
Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus. Biol Reprod (2013) 0.78
Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet (2015) 0.75
Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One (2015) 0.75
Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom (2013) 0.75
A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo. Mol Endocrinol (2014) 0.75
Application of (13) C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom (2015) 0.75