Published in Int J Cancer on January 10, 2004
Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression. PLoS One (2009) 3.89
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am J Pathol (2005) 2.02
Endosialin (Tem1) is a marker of tumor-associated myofibroblasts and tumor vessel-associated mural cells. Am J Pathol (2008) 1.53
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity. Proc Natl Acad Sci U S A (2009) 1.34
Macrophage infiltration predicts a poor prognosis for human ewing sarcoma. Am J Pathol (2011) 1.30
Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices. Methods Mol Biol (2009) 1.27
Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. Am J Pathol (2007) 1.16
Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS One (2011) 1.16
Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment. Cancer Res (2013) 1.12
Changes in the expression of MMP2, MMP9, and ColIV in stromal cells in oral squamous tongue cell carcinoma: relationships and prognostic implications. J Exp Clin Cancer Res (2012) 1.07
Tumor stroma as targets for cancer therapy. Pharmacol Ther (2012) 1.06
The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions. BMC Cancer (2008) 1.00
Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling. Pflugers Arch (2014) 0.98
One cell, multiple roles: contribution of mesenchymal stem cells to tumor development in tumor microenvironment. Cell Biosci (2013) 0.97
Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions. Cell Commun Signal (2010) 0.95
Connexin43 expression levels influence intercellular coupling and cell proliferation of native murine cardiac fibroblasts. Cell Commun Adhes (2008) 0.93
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation. Am J Pathol (2010) 0.92
T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets. Cancer Microenviron (2010) 0.91
Temporal alterations in cardiac fibroblast function following induction of pressure overload. Cell Tissue Res (2010) 0.90
Breast tumor microenvironment: proteomics highlights the treatments targeting secretome. J Proteome Res (2008) 0.90
Loss of the promyelocytic leukemia protein in gastric cancer: implications for IP-10 expression and tumor-infiltrating lymphocytes. PLoS One (2011) 0.88
Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease. Am J Pathol (2007) 0.88
Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes. PLoS One (2013) 0.87
Proinflammatory cytokine synthesis by mucosal fibroblasts from mouse colitis is enhanced by interferon-gamma-mediated up-regulation of CD40 signalling. Clin Exp Immunol (2007) 0.86
Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression. Respir Res (2015) 0.85
Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway. Mol Cells (2013) 0.85
The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling. J Biol Chem (2014) 0.81
FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. BMC Cancer (2015) 0.80
Report on antibodies submitted to the stromal cell section of HLDA8. Cell Immunol (2005) 0.80
Fibroblast and T cells conditioned media induce maturation dendritic cell and promote T helper immune response. Vet Res Forum (2012) 0.79
Skin fibroblasts from individuals with Chediak-Higashi Syndrome (CHS) exhibit hyposensitive immunogenic response. Orphanet J Rare Dis (2014) 0.76
DNA Aptamers for the Characterization of Histological Structure of Lung Adenocarcinoma. Mol Ther Nucleic Acids (2016) 0.75
How Can We Treat Cancer Disease Not Cancer Cells? Cancer Res Treat (2016) 0.75
The influence of stromal cells and tumor-microenvironment-derived cytokines and chemokines on CD3(+)CD8(+) tumor infiltrating lymphocyte subpopulations. Oncoimmunology (2017) 0.75
11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI. J Endocrinol (2017) 0.75
Unusual dural substitute complications in pediatric patients. Childs Nerv Syst (2012) 0.75
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 7.32
Nomenclature of monocytes and dendritic cells in blood. Blood (2010) 6.63
In vivo analysis of dendritic cell development and homeostasis. Science (2009) 6.42
Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95
Langerhans cells arise from monocytes in vivo. Nat Immunol (2006) 5.46
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science (2010) 4.67
Multicellular tumor spheroids: an underestimated tool is catching up again. J Biotechnol (2010) 4.33
Migratory fate and differentiation of blood monocyte subsets. Immunobiology (2006) 4.30
Unravelling mononuclear phagocyte heterogeneity. Nat Rev Immunol (2010) 4.25
Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 4.17
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 4.04
Spheroid-based drug screen: considerations and practical approach. Nat Protoc (2009) 4.01
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques. Proc Natl Acad Sci U S A (2004) 3.85
Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol (2007) 3.75
Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med (2006) 3.43
Basophils enhance immunological memory responses. Nat Immunol (2008) 3.35
Comparison of gene expression profiles between human and mouse monocyte subsets. Blood (2009) 3.15
Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J Immunol (2008) 3.04
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A (2006) 3.00
Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res (2008) 2.84
Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells. Blood (2004) 2.76
Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J Exp Med (2008) 2.73
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med (2004) 2.68
Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood (2007) 2.64
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61
Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell (2007) 2.48
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. J Clin Invest (2011) 2.37
Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity (2004) 2.27
Modulation of dendritic cell trafficking to and from the airways. J Immunol (2006) 2.17
Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge? Int J Radiat Biol (2007) 2.12
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med (2009) 2.12
Monocyte trafficking in acute and chronic inflammation. Trends Immunol (2011) 2.05
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity (2012) 1.98
CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. J Exp Med (2011) 1.95
Identification of transcriptional regulators in the mouse immune system. Nat Immunol (2013) 1.79
Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.76
Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling. Arterioscler Thromb Vasc Biol (2010) 1.75
CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges. J Pathol (2012) 1.75
Optimization of methods to study pulmonary dendritic cell migration reveals distinct capacities of DC subsets to acquire soluble versus particulate antigen. J Immunol Methods (2008) 1.69
Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes. Immunity (2006) 1.63
The transcriptional landscape of αβ T cell differentiation. Nat Immunol (2013) 1.61
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression. Blood (2005) 1.58
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest (2013) 1.57
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis. Am J Pathol (2009) 1.54
Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells. Blood (2003) 1.47
Hypercholesterolemic mice exhibit lymphatic vessel dysfunction and degeneration. Am J Pathol (2009) 1.47
Lipopolysaccharide or whole bacteria block the conversion of inflammatory monocytes into dendritic cells in vivo. J Exp Med (2003) 1.39
CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity. FASEB J (2006) 1.34
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol (2009) 1.33
In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors. Cancer Res (2007) 1.30
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol (2008) 1.27
Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs. Nat Immunol (2006) 1.26
A reliable tool to determine cell viability in complex 3-d culture: the acid phosphatase assay. J Biomol Screen (2007) 1.23
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. J Immunol (2009) 1.22
RGD peptide functionalized and reconstituted high-density lipoprotein nanoparticles as a versatile and multimodal tumor targeting molecular imaging probe. FASEB J (2010) 1.21
MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells. J Immunol (2009) 1.21
Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity. J Immunol (2012) 1.21
Defects in N-glycosylation induce apoptosis in yeast. Mol Microbiol (2006) 1.20
GFP-transfected tumor cells are useful in examining early metastasis in vivo, but immune reaction precludes long-term tumor development studies in immunocompetent mice. Clin Exp Metastasis (2003) 1.19
Inflammation, lymphatic function, and dendritic cell migration. Lymphat Res Biol (2006) 1.19
FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. J Clin Invest (2003) 1.18
Tumor-associated fibroblasts recruit blood monocytes into tumor tissue. Eur J Immunol (2003) 1.16
Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J Immunol (2012) 1.15
Lymphatic transport of high-density lipoproteins and chylomicrons. J Clin Invest (2014) 1.15
Local apoptosis mediates clearance of macrophages from resolving inflammation in mice. Blood (2013) 1.12
Tumor-induced modulation of dendritic cell function. Cytokine Growth Factor Rev (2007) 1.09
Tumor metabolism as modulator of immune response and tumor progression. Semin Cancer Biol (2012) 1.09
Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release. Int J Oncol (2011) 1.08
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation. Int J Cancer (2011) 1.08
Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages. Virology (2006) 1.07
Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists? J Cancer Res Clin Oncol (2003) 1.07
Heat shock protein 70-reactivity is associated with increased cell surface density of CD94/CD56 on primary natural killer cells. Cell Stress Chaperones (2003) 1.07
Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma. PPAR Res (2009) 1.06
A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells. J Immunol (2006) 1.06
CD11b⁺, Ly6G⁺ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog (2011) 1.05
Suppression of T-cell responses by tumor metabolites. Cancer Immunol Immunother (2011) 1.04
Dendritic cell migration through the lymphatic vasculature to lymph nodes. Adv Immunol (2013) 1.03
Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem (2011) 1.03
Methods to study pulmonary dendritic cell migration. Methods Mol Biol (2010) 1.03
Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma. J Cell Biochem (2009) 0.99
FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments. J Immunol (2004) 0.98
Tumor necrosis factor-alpha activates NFkappaB to inhibit renin transcription by targeting cAMP-responsive element. J Biol Chem (2003) 0.97
EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells. Cancer Res (2012) 0.96
Brave little world: spheroids as an in vitro model to study tumor-immune-cell interactions. Cell Cycle (2006) 0.96
Autocrine type I IFN and contact with endothelium promote the presentation of influenza A virus by monocyte-derived APC. J Immunol (2003) 0.95
Inverse regulation of the ADAM-family members, decysin and MADDAM/ADAM19 during monocyte differentiation. Immunology (2003) 0.95
Cancer stem cells as a predictive factor in radiotherapy. Semin Radiat Oncol (2012) 0.95
Three-dimensional fibroblast-tumor cell interaction causes downregulation of RACK1 mRNA expression in breast cancer cells in vitro. Int J Cancer (2002) 0.94
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders. J Exp Med (2013) 0.94
Warburg phenotype in renal cell carcinoma: high expression of glucose-transporter 1 (GLUT-1) correlates with low CD8(+) T-cell infiltration in the tumor. Int J Cancer (2011) 0.94
Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia. J Immunol (2013) 0.93
Functional specialization of islet dendritic cell subsets. J Immunol (2012) 0.92
Genome and transcriptome profiles of CD133-positive colorectal cancer cells. Am J Pathol (2011) 0.92
CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell lines HCT-116. Radiother Oncol (2009) 0.92