Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMID 14654167)

Published in Life Sci on December 26, 2003

Authors

Shih-Hua Fang1, Yu-Chi Hou, Weng-Cheng Chang, Su-Lan Hsiu, Pei-Dawn Lee Chao, Bor-Luen Chiang

Author Affiliations

1: Department of Microbiology, School of Medicine, China Medical University, Taichung 404, Taiwan. shfang@mail.cmu.edu.tw

Articles citing this

Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex. Int J Nanomedicine (2011) 0.92

Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis. Clin Cancer Res (2007) 0.91

Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice. Cancer Chemother Pharmacol (2010) 0.89

Role of pigment epithelium-derived factor in stem/progenitor cell-associated neovascularization. J Biomed Biotechnol (2012) 0.85

Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. Evid Based Complement Alternat Med (2011) 0.84

Alleviating effects of morin against experimentally-induced diabetic osteopenia. Diabetol Metab Syndr (2013) 0.80

D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. Int J Mol Sci (2013) 0.80

Preclinical cancer chemoprevention studies using animal model of inflammation-associated colorectal carcinogenesis. Cancers (Basel) (2012) 0.78

Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats. Neurol Sci (2014) 0.78

Compositional and proteomic analyses of genetically modified broccoli (Brassica oleracea var. italica) harboring an agrobacterial gene. Int J Mol Sci (2014) 0.76

Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase. Int J Oncol (2016) 0.75

Online Coupling of Lab-on-Valve Format to Amperometry Based on Polyvinylpyrrolidone-Doped Carbon Paste Electrode and Its Application to the Analysis of Morin. J Anal Methods Chem (2012) 0.75

MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS. Afr J Tradit Complement Altern Med (2017) 0.75

Anti-inflammatory effect of certain dimethoxy flavones. Inflammopharmacology (2015) 0.75

Articles by these authors

Waning immunity to plasma-derived hepatitis B vaccine and the need for boosters 15 years after neonatal vaccination. Hepatology (2004) 2.74

Epidemiologic features of Kawasaki disease in Taiwan, 2003-2006. Pediatrics (2009) 1.85

Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71. Pediatr Res (2006) 1.50

Changing clinical presentations and survival pattern in trisomy 18. Pediatr Neonatol (2009) 1.48

Humoral and cellular immune responses to a hepatitis B vaccine booster 15-18 years after neonatal immunization. J Infect Dis (2008) 1.43

Quantitative assessment of allergic shiners in children with allergic rhinitis. J Allergy Clin Immunol (2009) 1.41

Antitumor and antimetastatic activity of IL-23. J Immunol (2003) 1.38

Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. J Pharm Pharmacol (2003) 1.35

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Res (2005) 1.21

Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus. Immunology (2006) 1.21

Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis. Drug Metab Dispos (2005) 1.21

Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways. J Leukoc Biol (2005) 1.20

Clinical characteristics of childhood erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in Taiwanese children. J Microbiol Immunol Infect (2004) 1.20

Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis. J Autoimmun (2006) 1.17

Epidemiologic features of Kawasaki disease in Taiwan, 1996-2002. Pediatrics (2004) 1.15

The immunobiology of Henoch-Schönlein purpura. Autoimmun Rev (2007) 1.13

Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life Sci (2002) 1.13

Oral immunization of mice using transgenic tomato fruit expressing VP1 protein from enterovirus 71. Vaccine (2006) 1.13

Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. Carcinogenesis (2003) 1.12

Proteomics and immunological analysis of a novel shrimp allergen, Pen m 2. J Immunol (2003) 1.12

Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus. Immunology (2008) 1.09

Clinical manifestations and outcomes of Henoch-Schönlein purpura: comparison between adults and children. Pediatr Neonatol (2009) 1.07

Enterovirus 71 virus-like particle vaccine: improved production conditions for enhanced yield. Vaccine (2010) 1.07

Small B cell lymphocytic lymphoma presenting as obstructive sleep apnea. World J Surg Oncol (2004) 1.06

Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites. J Agric Food Chem (2009) 1.04

Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Biol Pharm Bull (2003) 1.03

Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles. Vaccine (2011) 1.02

Proteome mining for novel IgE-binding proteins from the German cockroach (Blattella germanica) and allergen profiling of patients. Proteomics (2010) 1.01

Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases. Clin Rheumatol (2012) 1.00

Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives. J Autoimmun (2005) 1.00

Staphylococcus colonization in atopic dermatitis treated with fluticasone or tacrolimus with or without antibiotics. Ann Allergy Asthma Immunol (2007) 0.99

Necrotizing pneumococcal pneumonia in children: the role of pulmonary gangrene. Pediatr Pulmonol (2006) 0.99

Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome. J Formos Med Assoc (2005) 0.97

The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis. Autoimmun Rev (2011) 0.96

The protease allergen Pen c 13 induces allergic airway inflammation and changes in epithelial barrier integrity and function in a murine model. J Biol Chem (2011) 0.95

Antioxidant and anti-inflammatory potential of hesperetin metabolites obtained from hesperetin-administered rat serum: an ex vivo approach. J Agric Food Chem (2011) 0.95

Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid. J Nutr Biochem (2005) 0.95

Impact of maternal and neonatal factors on CD34+ cell count, total nucleated cells, and volume of cord blood. Pediatr Transplant (2008) 0.95

An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and MAPK pathways. J Leukoc Biol (2009) 0.94

Antioxidative and hypolipidemic effects of barley leaf essence in a rabbit model of atherosclerosis. Jpn J Pharmacol (2002) 0.94

Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling. J Immunol (2009) 0.94

Patient data, early SARS epidemic, Taiwan. Emerg Infect Dis (2004) 0.94

A new insight into hepatitis C vaccine development. J Biomed Biotechnol (2010) 0.94

Renal manifestations in Henoch-Schönlein purpura: a 10-year clinical study. Pediatr Nephrol (2005) 0.93

Effect of sulforaphane on growth inhibition in human brain malignant glioma GBM 8401 cells by means of mitochondrial- and MEK/ERK-mediated apoptosis pathway. Cell Biochem Biophys (2012) 0.93

Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. Biol Pharm Bull (2004) 0.93

Juvenile idiopathic arthritis-associated uveitis: a nationwide population-based study in Taiwan. PLoS One (2013) 0.93

Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma. Br J Pharmacol (2010) 0.92

Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: identification of two functional regions. J Immunol (2004) 0.92

A novel phycobiliprotein alleviates allergic airway inflammation by modulating immune responses. Am J Respir Crit Care Med (2010) 0.92

Sex differences in spontaneous versus induced animal models of autoimmunity. Autoimmun Rev (2011) 0.92

Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness. Mol Ther (2007) 0.91

Over-expression of receptor activator of nuclear factor-kappaB ligand (RANKL), inflammatory cytokines, and chemokines in periprosthetic osteolysis of loosened total hip arthroplasty. Biomaterials (2009) 0.91

Propolis extracts exhibit an immunoregulatory activity in an OVA-sensitized airway inflammatory animal model. Int Immunopharmacol (2006) 0.91

Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-γ+CD4+ regulatory T cells to control transplant arteriosclerosis. J Immunol (2013) 0.91

Methimazole-induced lupus erythematosus: a case report. J Microbiol Immunol Infect (2003) 0.91

Potential ex vivo immunomodulatory effects of San-Huang-Xie-Xin-Tang and its component herbs on mice and humans. J Ethnopharmacol (2009) 0.90

Rhizomes of Gastrodia elata B(L) possess antidepressant-like effect via monoamine modulation in subchronic animal model. Am J Chin Med (2009) 0.90

Retrospective analysis of mortality and morbidity of pediatric systemic lupus erythematosus in the past two decades. J Microbiol Immunol Infect (2003) 0.90

Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan. J Infect Dis (2005) 0.90

Increased levels of serum-specific immunoglobulin e to staphylococcal enterotoxin a and B in patients with allergic rhinitis and bronchial asthma. Int Arch Allergy Immunol (2005) 0.90

Effect of ethanol extracts of three Chinese medicinal plants with anti-diarrheal properties on ion transport of the rat intestinal epithelia. J Pharmacol Sci (2004) 0.89

The inhibitory mechanism of YC-1, a benzyl indazole, on smooth muscle cell proliferation: an in vitro and in vivo study. J Pharmacol Sci (2004) 0.89

Genetics and immunopathogenesis of IgA nephropathy. Clin Rev Allergy Immunol (2011) 0.89

Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis. Planta Med (2004) 0.89

Correlation between age and allergens in pediatric atopic dermatitis. Ann Allergy Asthma Immunol (2004) 0.89

Regulatory T cells induced by mucosal B cells alleviate allergic airway hypersensitivity. Am J Respir Cell Mol Biol (2011) 0.89

Aortic aneurysm in systemic lupus erythematosus. J Microbiol Immunol Infect (2004) 0.88

Separation and detection of rare cells in a microfluidic disk via negative selection. Lab Chip (2010) 0.88

Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. Ann Allergy Asthma Immunol (2008) 0.88

Co-delivery of GM-CSF gene enhances the immune responses of hepatitis C viral core protein-expressing DNA vaccine: role of dendritic cells. J Med Virol (2002) 0.88

Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats. J Pharm Sci (2010) 0.88

Role of bacterial pathogens in atopic dermatitis. Clin Rev Allergy Immunol (2007) 0.88

Carnosic acid prevents the migration of human aortic smooth muscle cells by inhibiting the activation and expression of matrix metalloproteinase-9. Br J Nutr (2008) 0.88

Early or late surgical ligation of medical refractory patent ductus arteriosus in premature infants. J Formos Med Assoc (2009) 0.88

The antioxidant effects of quercetin metabolites on the prevention of high glucose-induced apoptosis of human umbilical vein endothelial cells. Br J Nutr (2008) 0.87

α-Galactosylceramide-induced airway eosinophilia is mediated through the activation of NKT cells. J Immunol (2011) 0.87

Dermatophagoides pteronyssinus 2 regulates nerve growth factor release to induce airway inflammation via a reactive oxygen species-dependent pathway. Am J Physiol Lung Cell Mol Physiol (2010) 0.87

Pharmacokinetic and pharmacodynamic interactions of morin and cyclosporin. Toxicol Appl Pharmacol (2005) 0.87

Type I IL-1 receptor (IL-1RI) as potential new therapeutic target for bronchial asthma. Mediators Inflamm (2010) 0.87

Effects of overexpression of IL-10, IL-12, TGF-beta and IL-4 on allergen induced change in bronchial responsiveness. Respir Res (2006) 0.86

Fas-ligand-expressing adenovirus-transfected dendritic cells decrease allergen-specific T cells and airway inflammation in a murine model of asthma. J Mol Med (Berl) (2006) 0.86

Increase of adiponectin receptor gene expression by physical exercise in soleus muscle of obese Zucker rats. Eur J Appl Physiol (2006) 0.86

Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model. Int Immunopharmacol (2005) 0.86

Cyclosporin A therapy for steroid-dependent Henoch-Schönlein purpura. J Microbiol Immunol Infect (2003) 0.86

Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J Leukoc Biol (2007) 0.86

The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells. BMC Immunol (2009) 0.86

Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Planta Med (2010) 0.86

Effects of adenovirus-expressing IL-10 in alleviating airway inflammation in asthma. J Gene Med (2006) 0.85

Autologous mesenchymal stem cells prevent transplant arteriosclerosis by enhancing local expression of interleukin-10, interferon-γ, and indoleamine 2,3-dioxygenase. Cell Transplant (2012) 0.85