Published in Clin Chem on December 04, 2003
Candidate-based proteomics in the search for biomarkers of cardiovascular disease. J Physiol (2004) 2.42
Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutr Metab (Lond) (2011) 1.58
Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment. Mol Genet Metab (2010) 1.03
A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab (2010) 1.00
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease. J Hepatol (2010) 0.99
A simple rapid immunoassay for S-adenosylhomocysteine in plasma. J Nutr Biochem (2007) 0.86
Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine. Mol Genet Metab (2011) 0.84
Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase. J Clin Biochem Nutr (2010) 0.81
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med (2009) 0.81
The use of mass spectrometry for analysing metabolite biomarkers in epidemiology: methodological and statistical considerations for application to large numbers of biological samples. Eur J Epidemiol (2016) 0.80
Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma. Clin Chim Acta (2013) 0.80
Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.80
Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts. FASEB J (2014) 0.79
Metabolic profiling of total homocysteine and related compounds in hyperhomocysteinemia: utility and limitations in diagnosing the cause of puzzling thrombophilia in a family. JIMD Rep (2013) 0.78
Epigenetic synergies between biotin and folate in the regulation of pro-inflammatory cytokines and repeats. Scand J Immunol (2013) 0.77
A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus. Clin Chim Acta (2008) 0.76
Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats. Nutrients (2016) 0.76
Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia. Metabolism (2007) 0.76
Mathematical Modeling of the Methionine Cycle and Transsulfuration Pathway in Individuals with Autism Spectrum Disorder. J Theor Biol (2016) 0.76
Time-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats. Sci Rep (2016) 0.75
Median nerve superficial to the transverse carpal ligament. Orthopedics (2015) 1.97
Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke (2005) 1.91
Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr (2007) 1.76
Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem (2008) 1.73
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. Am J Clin Nutr (2011) 1.53
Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther (2002) 1.51
Vitamin B12 deficiency as a worldwide problem. Annu Rev Nutr (2004) 1.46
Comparing McRoberts' and Rubin's maneuvers for initial management of shoulder dystocia: an objective evaluation. Am J Obstet Gynecol (2005) 1.40
Episiotomy versus fetal manipulation in managing severe shoulder dystocia: a comparison of outcomes. Am J Obstet Gynecol (2004) 1.39
Vitamin B12, homocysteine and carotid plaque in the era of folic acid fortification of enriched cereal grain products. CMAJ (2005) 1.34
Methyl balance and transmethylation fluxes in humans. Am J Clin Nutr (2007) 1.33
S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proc Natl Acad Sci U S A (2004) 1.32
High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations. Hum Mutat (2002) 1.29
Zinc, gravida, infection, and iron, but not vitamin B-12 or folate status, predict hemoglobin during pregnancy in Southern Ethiopia. J Nutr (2008) 1.29
Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans. Am J Clin Nutr (2012) 1.17
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem (2008) 1.14
Versatility in corrinoid salvaging and remodeling pathways supports corrinoid-dependent metabolism in Dehalococcoides mccartyi. Appl Environ Microbiol (2012) 1.14
Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency. Metabolism (2002) 1.08
Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency. Mol Genet Metab (2007) 1.04
Serum methionine metabolites are risk factors for metastatic prostate cancer progression. PLoS One (2011) 1.03
Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment. Mol Genet Metab (2010) 1.03
Hyperhomocysteinemia and vitamin B-12 deficiency in elderly using Title IIIc nutrition services. Am J Clin Nutr (2003) 1.01
MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr (2010) 1.01
Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol (2002) 1.01
A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab (2010) 1.00
Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death. J Biol Chem (2012) 1.00
Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA. J Biol Chem (2011) 0.99
Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns. Am J Clin Nutr (2004) 0.98
Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient with cystathionine beta-synthase (CBS) deficiency. Am J Med Genet (2002) 0.97
Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults. J Am Geriatr Soc (2002) 0.96
Enzymatic activity of methionine adenosyltransferase variants identified in patients with persistent hypermethioninemia. Mol Genet Metab (2010) 0.94
Cystathionine gamma-lyase: Clinical, metabolic, genetic, and structural studies. Mol Genet Metab (2009) 0.93
Prioritizing posterior arm delivery during severe shoulder dystocia. Obstet Gynecol (2003) 0.93
Infantile hypermethioninemia and hyperhomocysteinemia due to high methionine intake: a diagnostic trap. Mol Genet Metab (2003) 0.92
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells. Chem Biol Interact (2004) 0.92
Sustainable growth of Dehalococcoides mccartyi 195 by corrinoid salvaging and remodeling in defined lactate-fermenting consortia. Appl Environ Microbiol (2014) 0.91
Cystathionine beta-synthase is coordinately regulated with proliferation through a redox-sensitive mechanism in cultured human cells and Saccharomyces cerevisiae. J Cell Physiol (2002) 0.90
Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population. Am J Clin Nutr (2010) 0.90
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration. J Nutr (2012) 0.89
Prevalence and predictors of anemia in a population-based study of octogenarians and centenarians in Georgia. J Gerontol A Biol Sci Med Sci (2011) 0.89
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr (2012) 0.88
Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. Am J Clin Nutr (2013) 0.87
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk. Mol Genet Metab (2011) 0.86
Elevated methylmalonic acid is related to cognitive impairement in older adults enrolled in an elderly nutrition program. J Nutr Elder (2005) 0.85
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. Clin Chim Acta (2008) 0.84
Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine. Mol Genet Metab (2011) 0.84
Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria. Mol Genet Metab (2011) 0.83
Profiles of cognitive functioning in a population-based sample of centenarians using factor mixture analysis. Exp Aging Res (2013) 0.82
Age-related hearing loss, methylmalonic acid, and vitamin B12 status in older adults. J Nutr Elder (2006) 0.82
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women. Clin Chim Acta (2007) 0.82
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med (2009) 0.81
Shoulder dystocia. Clin Perinatol (2007) 0.80
Cost-effective therapeutic hypothermia treatment device for hypoxic ischemic encephalopathy. Med Devices (Auckl) (2013) 0.80
Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes. Mol Genet Metab (2012) 0.80
Maternal diet supplemented with methyl-donors protects against atherosclerosis in F1 ApoE(-/-) mice. PLoS One (2013) 0.80
Risk factors for brachial plexus injury with and without shoulder dystocia. Am J Obstet Gynecol (2006) 0.79
Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice. J Nutr (2013) 0.79
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells. Mutat Res (2008) 0.78
Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. Free Radic Biol Med (2005) 0.78
Brachial plexus palsy causation. Birth (2003) 0.78
Randomized trial of McRoberts versus lithotomy positioning to decrease the force that is applied to the fetus during delivery. Am J Obstet Gynecol (2004) 0.78
Metabolic profiling of total homocysteine and related compounds in hyperhomocysteinemia: utility and limitations in diagnosing the cause of puzzling thrombophilia in a family. JIMD Rep (2013) 0.78
Increased MMA concentration and body mass index are associated with spontaneous abortion in Brazilian women: a pilot study. Clin Chim Acta (2009) 0.78
Elevated serum S-adenosylhomocysteine in cobalamin-deficient elderly and response to treatment. Am J Clin Nutr (2006) 0.77
Measuring bioimpedance in the human uterine cervix: towards early detection of preterm labor. Conf Proc IEEE Eng Med Biol Soc (2004) 0.76
Reducing the risk of shoulder dystocia and associated brachial plexus injury. Obstet Gynecol Clin North Am (2011) 0.76
Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia. Metabolism (2007) 0.76
Severe brachial plexus injury in the posterior arm: An alternative explanation. Am J Obstet Gynecol (2002) 0.75
On redefining shoulder dystocia and at-risk populations. Am J Obstet Gynecol (2006) 0.75
Reply: To PMID 25611425. Orthopedics (2015) 0.75
Complete brachial plexus impairment: a traction-related injury. Am J Obstet Gynecol (2003) 0.75
Computer modeling of shoulder dystocia. Am J Obstet Gynecol (2004) 0.75
Management of shoulder dystocia. Lancet (2005) 0.75
The descent curve of the grand multiparous woman. Am J Obstet Gynecol (2003) 0.75
Effect of operative vaginal delivery on the outcome of permanent brachial plexus injury. J Reprod Med (2003) 0.75
After shoulder dystocia: managing the subsequent pregnancy and delivery. Semin Perinatol (2007) 0.75
Effect of epidural anaesthesia on clinician-applied force during vaginal delivery. Am J Obstet Gynecol (2004) 0.75
Simulating complicated human birth for research and training. Conf Proc IEEE Eng Med Biol Soc (2004) 0.75
Severe shoulder dystocia with a small-for-gestationaI-age infant: a case report. J Reprod Med (2011) 0.75
Intrapartum risk factors for permanent brachial plexus injury. Am J Obstet Gynecol (2003) 0.75
Assessment of upper airway patency in spontaneously breathing non-intubated neonates and infants undergoing conventional MRI of head and neck. Childs Nerv Syst (2015) 0.75
A biofidelic birthing simulator. Models for research and training in complicated human births. IEEE Eng Med Biol Mag (2005) 0.75