| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.
|
Pharmacol Rev
|
2005
|
5.25
|
|
2
|
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.
|
EMBO J
|
2004
|
2.15
|
|
3
|
A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia.
|
Curr Biol
|
2007
|
1.70
|
|
4
|
Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels.
|
Mol Pharmacol
|
2008
|
1.63
|
|
5
|
Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons.
|
Proc Natl Acad Sci U S A
|
2006
|
1.62
|
|
6
|
The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution.
|
J Neurosci
|
2004
|
1.57
|
|
7
|
Ca(V)3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons.
|
Eur J Neurosci
|
2006
|
1.48
|
|
8
|
International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels.
|
Pharmacol Rev
|
2003
|
1.43
|
|
9
|
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures.
|
Sci Transl Med
|
2012
|
1.39
|
|
10
|
UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants.
|
Curr Biol
|
2007
|
1.36
|
|
11
|
Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines.
|
J Neurosci
|
2009
|
1.36
|
|
12
|
Role of voltage-gated calcium channels in ascending pain pathways.
|
Brain Res Rev
|
2008
|
1.35
|
|
13
|
Contributions of T-type calcium channel isoforms to neuronal firing.
|
Channels (Austin)
|
2010
|
1.20
|
|
14
|
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy.
|
J Neurosci
|
2009
|
1.20
|
|
15
|
Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate.
|
J Neurosci
|
2007
|
1.14
|
|
16
|
Differential inhibition of T-type calcium channels by neuroleptics.
|
J Neurosci
|
2002
|
1.11
|
|
17
|
The C. elegans T-type calcium channel CCA-1 boosts neuromuscular transmission.
|
J Exp Biol
|
2005
|
1.11
|
|
18
|
Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties.
|
J Neurosci
|
2003
|
1.11
|
|
19
|
T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome.
|
Proc Natl Acad Sci U S A
|
2011
|
1.06
|
|
20
|
Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies.
|
Channels (Austin)
|
2009
|
1.05
|
|
21
|
Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy.
|
J Biol Chem
|
2004
|
1.03
|
|
22
|
Pseudomigraine with lymphocytic pleocytosis: a calcium channelopathy? Clinical description of 10 cases and genetic analysis of the familial hemiplegic migraine gene CACNA1A.
|
Headache
|
2003
|
1.03
|
|
23
|
Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy.
|
Ann Neurol
|
2005
|
0.97
|
|
24
|
T-type calcium channels in burst-firing, network synchrony, and epilepsy.
|
Biochim Biophys Acta
|
2012
|
0.96
|
|
25
|
Splice-variant changes of the Ca(V)3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development.
|
Channels (Austin)
|
2010
|
0.95
|
|
26
|
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
|
J Pharmacol Exp Ther
|
2010
|
0.94
|
|
27
|
Contribution of calcium-dependent facilitation to synaptic plasticity revealed by migraine mutations in the P/Q-type calcium channel.
|
Proc Natl Acad Sci U S A
|
2010
|
0.93
|
|
28
|
A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement.
|
J Neurosci
|
2008
|
0.93
|
|
29
|
Voltage-gated calcium channels and disease.
|
Biofactors
|
2011
|
0.91
|
|
30
|
Low threshold T-type calcium channels as targets for novel epilepsy treatments.
|
Br J Clin Pharmacol
|
2014
|
0.89
|
|
31
|
Contributions of T-type voltage-gated calcium channels to postsynaptic calcium signaling within Purkinje neurons.
|
Cerebellum
|
2012
|
0.88
|
|
32
|
A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain.
|
Pain
|
2011
|
0.88
|
|
33
|
Functional implications of a novel EA2 mutation in the P/Q-type calcium channel.
|
Ann Neurol
|
2004
|
0.87
|
|
34
|
Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.
|
J Biol Chem
|
2007
|
0.87
|
|
35
|
Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin.
|
J Pharmacol Exp Ther
|
2003
|
0.86
|
|
36
|
Scaffold-based design and synthesis of potent N-type calcium channel blockers.
|
Bioorg Med Chem Lett
|
2009
|
0.86
|
|
37
|
Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy.
|
Epilepsia
|
2006
|
0.86
|
|
38
|
Modulation of low-voltage-activated T-type Ca²⁺ channels.
|
Biochim Biophys Acta
|
2012
|
0.83
|
|
39
|
Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6.
|
J Pharmacol Exp Ther
|
2005
|
0.81
|
|
40
|
Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
|
Mol Pharmacol
|
2011
|
0.81
|
|
41
|
Block of voltage-gated calcium channels stimulates dopamine efflux in rat mesocorticolimbic system.
|
Neuropharmacology
|
2009
|
0.81
|
|
42
|
A fluorescence-based high-throughput screening assay for the identification of T-type calcium channel blockers.
|
Assay Drug Dev Technol
|
2009
|
0.81
|
|
43
|
Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors.
|
Bioorg Med Chem Lett
|
2012
|
0.81
|
|
44
|
Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy.
|
Pflugers Arch
|
2014
|
0.80
|
|
45
|
Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons.
|
Mol Pain
|
2011
|
0.80
|
|
46
|
Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors.
|
Bioorg Med Chem Lett
|
2010
|
0.80
|
|
47
|
Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans.
|
PLoS Genet
|
2012
|
0.79
|
|
48
|
Modular, efficient synthesis of asymmetrically substituted piperazine scaffolds as potent calcium channel blockers.
|
Bioorg Med Chem Lett
|
2013
|
0.79
|
|
49
|
Malaysian siblings with friedreich ataxia and chorea: a novel deletion in the frataxin gene.
|
Can J Neurol Sci
|
2004
|
0.78
|
|
50
|
Advances in voltage-gated calcium channel structure, function and physiology.
|
Biochim Biophys Acta
|
2013
|
0.77
|
|
51
|
Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels.
|
J Neurochem
|
2011
|
0.76
|
|
52
|
Modulating modulation: crosstalk between regulatory pathways of presynaptic calcium channels.
|
Mol Interv
|
2002
|
0.76
|
|
53
|
Treatments for neuropathic pain differentially affect delayed matching accuracy by macaques: effects of amitriptyline and gabapentin.
|
Pain
|
2010
|
0.76
|
|
54
|
The unusual suspects: Regulation of retinal calcium channels by somatostatin.
|
Channels (Austin)
|
2015
|
0.75
|