Published in Gene on December 24, 2003
Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell (2008) 3.15
p53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genet (2014) 0.93
Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish. Dev Biol (2014) 0.89
p63 mediates an apoptotic response to pharmacological and disease-related ER stress in the developing epidermis. Dev Cell (2011) 0.89
Zebrafish models of p53 functions. Cold Spring Harb Perspect Biol (2010) 0.88
Transcriptional control of terminal nephron differentiation. Am J Physiol Renal Physiol (2008) 0.85
Differential expression of four protocadherin alpha and gamma clusters in the developing and adult zebrafish: DrPcdh2gamma but not DrPcdh1gamma is expressed in neuronal precursor cells, ependymal cells and non-neural epithelia. Dev Genes Evol (2007) 0.82
p53 selectively regulates developmental apoptosis of rod photoreceptors. PLoS One (2013) 0.79
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nat Methods (2011) 2.85
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell (2008) 2.17
The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol (2007) 2.10
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev (2002) 2.02
FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish. Dev Biol (2007) 2.02
Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. Dev Cell (2008) 1.82
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (2003) 1.79
Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm. Dev Cell (2002) 1.68
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (2007) 1.66
PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med (2013) 1.66
Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. PLoS One (2006) 1.60
Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol (2007) 1.58
Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation. Development (2006) 1.57
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development (2008) 1.54
parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. Development (2002) 1.53
Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: implications for the evolution of axial patterning. Dev Biol (2006) 1.44
Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet (2012) 1.43
Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol (2009) 1.42
REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Dev Dyn (2007) 1.38
Control of Dpp morphogen signalling by a secreted feedback regulator. Nat Cell Biol (2010) 1.38
Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet (2011) 1.37
Zebrafish in endocrine systems: recent advances and implications for human disease. Annu Rev Physiol (2011) 1.36
Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis. Development (2007) 1.32
SMIF, a Smad4-interacting protein that functions as a co-activator in TGFbeta signalling. Nat Cell Biol (2002) 1.31
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet (2009) 1.29
Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet (2010) 1.25
Adenohypophysis formation in the zebrafish and its dependence on sonic hedgehog. Dev Biol (2003) 1.21
Differentiation of the vertebrate retina is coordinated by an FGF signaling center. Dev Cell (2005) 1.20
Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev Cell (2008) 1.20
Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development (2004) 1.19
Diversin regulates heart formation and gastrulation movements in development. Proc Natl Acad Sci U S A (2006) 1.16
Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development (2004) 1.13
Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. Am J Hum Genet (2011) 1.12
Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling. Am J Hum Genet (2010) 1.11
Foxi3 transcription factors and Notch signaling control the formation of skin ionocytes from epidermal precursors of the zebrafish embryo. Dev Biol (2007) 1.11
Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development (2008) 1.11
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Mol Endocrinol (2003) 1.09
Zebrafish as a powerful vertebrate model system for in vivo studies of cell death. Semin Cancer Biol (2006) 1.08
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest (2014) 1.08
Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Dev Biol (2005) 1.07
Destabilization of DeltaNp63alpha by Nedd4-mediated ubiquitination and Ubc9-mediated sumoylation, and its implications on dorsoventral patterning of the zebrafish embryo. Cell Cycle (2005) 1.07
Induction and patterning of neuronal development, and its connection to cell cycle control. Curr Opin Neurobiol (2003) 1.05
Adult zebrafish as a model system for cutaneous wound-healing research. J Invest Dermatol (2013) 1.04
Maternally supplied Smad5 is required for ventral specification in zebrafish embryos prior to zygotic Bmp signaling. Dev Biol (2002) 1.02
Glucocorticoids play a key role in circadian cell cycle rhythms. PLoS Biol (2007) 1.01
PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis. Mol Cell Biol (2009) 1.00
The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish. Development (2009) 1.00
Ubc9 regulates mitosis and cell survival during zebrafish development. Mol Biol Cell (2006) 1.00
Pituitary-interrenal interaction in zebrafish interrenal organ development. Mol Endocrinol (2006) 0.98
Genetic analysis of adenohypophysis formation in zebrafish. Mol Endocrinol (2004) 0.96
The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis. Development (2006) 0.95
Hemicentin 2 and Fibulin 1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development. Dev Biol (2012) 0.95
Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened. Dev Biol (2006) 0.94
Zebrafish pit1 mutants lack three pituitary cell types and develop severe dwarfism. Mol Endocrinol (2004) 0.93
Bmp signaling exerts opposite effects on cardiac differentiation. Circ Res (2012) 0.92
A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet (2012) 0.91
Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One (2010) 0.91
A zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment. Mech Dev (2002) 0.90
Zebrafish grainyhead-like1 is a common marker of different non-keratinocyte epidermal cell lineages, which segregate from each other in a Foxi3-dependent manner. Int J Dev Biol (2010) 0.90
The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling. J Biol Chem (2012) 0.89
Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene. Development (2013) 0.88
fras1 shapes endodermal pouch 1 and stabilizes zebrafish pharyngeal skeletal development. Development (2012) 0.88
Loss of maternal Smad5 in zebrafish embryos affects patterning and morphogenesis of optic primordia. Dev Dyn (2003) 0.87
Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis. Dev Biol (2006) 0.86
Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas. Mol Biol Cell (2012) 0.86
Molecular genetics of pituitary development in zebrafish. Semin Cell Dev Biol (2007) 0.86
Expression of the somatolactin beta gene during zebrafish embryonic development. Gene Expr Patterns (2005) 0.85
Biosynthesis of Wdr16, a marker protein for kinocilia-bearing cells, starts at the time of kinocilia formation in rat, and wdr16 gene knockdown causes hydrocephalus in zebrafish. J Neurochem (2007) 0.84
Fgf signaling induces posterior neuroectoderm independently of Bmp signaling inhibition. Dev Dyn (2004) 0.84
A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner ear. PLoS One (2009) 0.83
Differential expression of four protocadherin alpha and gamma clusters in the developing and adult zebrafish: DrPcdh2gamma but not DrPcdh1gamma is expressed in neuronal precursor cells, ependymal cells and non-neural epithelia. Dev Genes Evol (2007) 0.82
How to make a teleost adenohypophysis: molecular pathways of pituitary development in zebrafish. Mol Cell Endocrinol (2009) 0.80
Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development (2013) 0.79
BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin. PLoS One (2011) 0.79
Basement membrane diseases in zebrafish. Methods Cell Biol (2011) 0.78
The HMG-box transcription factor Sox4b is required for pituitary expression of gata2a and specification of thyrotrope and gonadotrope cells in zebrafish. Mol Endocrinol (2012) 0.76