Published in Mol Cell Biol on January 01, 2004
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
Multiple links between transcription and splicing. RNA (2004) 4.90
Epigenetics in alternative pre-mRNA splicing. Cell (2011) 4.74
Alternative splicing: a pivotal step between eukaryotic transcription and translation. Nat Rev Mol Cell Biol (2013) 3.33
P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner. Mol Biol Cell (2005) 2.53
Paraspeckles. Cold Spring Harb Perspect Biol (2010) 1.48
Cotranscriptional exon skipping in the genotoxic stress response. Nat Struct Mol Biol (2010) 1.39
Transcriptional activity of androgen receptor is modulated by two RNA splicing factors, PSF and p54nrb. Mol Cell Biol (2007) 1.35
SWI/SNF associates with nascent pre-mRNPs and regulates alternative pre-mRNA processing. PLoS Genet (2009) 1.22
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22
Protein arginine methyltransferase 6 regulates multiple aspects of gene expression. Nucleic Acids Res (2010) 1.21
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Global dissection of alternative splicing in paleopolyploid soybean. Plant Cell (2014) 1.15
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The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity. Proc Natl Acad Sci U S A (2009) 1.10
Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles. J Cell Biol (2015) 1.10
Nuclear receptor coactivators: structural and functional biochemistry. Biochemistry (2010) 1.06
Coactivators in PPAR-Regulated Gene Expression. PPAR Res (2010) 1.04
HIFs enhance the transcriptional activation and splicing of adrenomedullin. Mol Cancer Res (2014) 1.03
SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexes. PLoS One (2012) 1.01
Where splicing joins chromatin. Nucleus (2011) 0.98
Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res (2008) 0.96
Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation. J Biol Chem (2009) 0.95
Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing. J Steroid Biochem Mol Biol (2007) 0.95
The role of nuclear bodies in gene expression and disease. Biology (Basel) (2013) 0.91
Acinus-S' represses retinoic acid receptor (RAR)-regulated gene expression through interaction with the B domains of RARs. Mol Cell Biol (2008) 0.90
Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation. Nucleic Acids Res (2007) 0.89
RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J (2014) 0.89
A G-tract element in apoptotic agents-induced alternative splicing. Nucleic Acids Res (2008) 0.88
How to build a paraspeckle. Genome Biol (2009) 0.88
Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro. J Biol Chem (2009) 0.87
Regulation of ERK1 gene expression by coactivator proteins. Biochem J (2005) 0.87
Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature (2016) 0.87
VEGF spliced variants: possible role of anti-angiogenesis therapy. J Nucleic Acids (2011) 0.86
Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol (2007) 0.86
RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing. Genet Res Int (2011) 0.84
Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors. J Cell Biochem (2009) 0.84
Hypoxia regulates alternative splicing of HIF and non-HIF target genes. Mol Cancer Res (2014) 0.83
Bipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activation. EMBO J (2009) 0.81
Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function. J Virol (2015) 0.80
Identification and characterization of PNRC splicing variants. Gene (2008) 0.79
Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway. PLoS One (2011) 0.79
Heterogeneous nuclear ribonucleoprotein R cooperates with mediator to facilitate transcription reinitiation on the c-Fos gene. PLoS One (2013) 0.78
Vitamin D and alternative splicing of RNA. J Steroid Biochem Mol Biol (2014) 0.78
The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing. J Lipid Res (2014) 0.78
EBV noncoding RNA EBER2 interacts with host RNA-binding proteins to regulate viral gene expression. Proc Natl Acad Sci U S A (2016) 0.77
The RNA Binding Complexes NF45-NF90 and NF45-NF110 Associate Dynamically with the c-fos Gene and Function as Transcriptional Coactivators. J Biol Chem (2015) 0.76
NFAT1 and NFAT3 cooperate with HDAC4 during regulation of alternative splicing of PMCA isoforms in PC12 cells. PLoS One (2014) 0.76
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors. Nat Commun (2016) 0.75
RNA Splicing Factors and RNA-Directed DNA Methylation. Biology (Basel) (2014) 0.75
LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies. Int J Mol Sci (2017) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
An extensive network of coupling among gene expression machines. Nature (2002) 11.84
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Messenger-RNA-binding proteins and the messages they carry. Nat Rev Mol Cell Biol (2002) 8.81
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A unified theory of gene expression. Cell (2002) 7.61
Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature (2002) 7.60
Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem Sci (2000) 7.54
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PSF and p54(nrb)/NonO--multi-functional nuclear proteins. FEBS Lett (2002) 3.06
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell (2000) 3.00
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Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase. J Biol Chem (2002) 2.01
The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J (2001) 1.92
A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. J Biol Chem (1999) 1.92
PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors. Mol Cell Biol (2001) 1.85
Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing. EMBO J (2001) 1.76
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
PSF and p54nrb bind a conserved stem in U5 snRNA. RNA (2002) 1.66
Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM). J Biol Chem (2001) 1.66
Modulation of an RNA-binding protein by abscisic-acid-activated protein kinase. Nature (2002) 1.65
A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2. Mol Cell (1998) 1.61
Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm. Bioessays (2001) 1.59
NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss. Mol Cell Biol (1993) 1.57
Coordination between transcription and pre-mRNA processing. FEBS Lett (2001) 1.45
Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator. Proc Natl Acad Sci U S A (2000) 1.43
Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR. J Biol Chem (2000) 1.42
Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol (2002) 1.42
Promoter architecture modulates CFTR exon 9 skipping. J Biol Chem (2002) 1.41
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein. Mol Cell Biol (2000) 1.41
The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO. Mol Cell Biol (1997) 1.41
Cloning and characterization of RAP250, a novel nuclear receptor coactivator. J Biol Chem (2000) 1.31
Identification of N(G)-methylarginine residues in human heterogeneous RNP protein A1: Phe/Gly-Gly-Gly-Arg-Gly-Gly-Gly/Phe is a preferred recognition motif. Biochemistry (1997) 1.28
Heterogeneous ribonucleoprotein A1 is part of an exon-specific splice-silencing complex controlled by oncogenic signaling pathways. J Biol Chem (2000) 1.23
Multifunctional proteins suggest connections between transcriptional and post-transcriptional processes. Bioessays (1997) 1.21
NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on. Genes Dev (2002) 1.10
Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specific DNA-binding protein. Biochem J (1999) 1.10
Insulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA. Proc Natl Acad Sci U S A (2001) 1.06
The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain. J Biol Chem (1997) 0.99
Delivering messages from the 3' end. Proc Natl Acad Sci U S A (2001) 0.93
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Combinatorial control of gene expression by nuclear receptors and coregulators. Cell (2002) 8.01
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell (2002) 4.31
Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev (2004) 3.74
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer (2009) 3.33
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell (2007) 2.69
Nuclear receptor coregulators and human disease. Endocr Rev (2007) 2.65
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell (2007) 2.57
The expanding cosmos of nuclear receptor coactivators. Cell (2006) 2.57
Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (2002) 2.53
Retracted Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell (2009) 2.48
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
Transoral robotic surgery for advanced oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg (2010) 2.31
Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell (2007) 2.31
Transoral robotic surgery: radical tonsillectomy. Arch Otolaryngol Head Neck Surg (2007) 2.28
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res (2004) 2.07
Minireview: nuclear receptor coactivators--an update. Endocrinology (2002) 2.04
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol (2007) 2.02
Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol (2006) 1.94
Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab (2011) 1.89
Reproductive functions of progesterone receptors. Recent Prog Horm Res (2002) 1.82
Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell (2005) 1.82
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A (2008) 1.80
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol (2008) 1.75
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol (2005) 1.74
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A (2010) 1.72
Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A (2005) 1.72
Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell (2005) 1.66
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A (2013) 1.66
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A (2008) 1.62
A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol (2002) 1.61
Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res (2005) 1.60
Expanding functional diversity of the coactivators. Trends Biochem Sci (2005) 1.57
SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol Cell (2006) 1.57
Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem (2010) 1.57
Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet (2013) 1.56
Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol (2012) 1.55
In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release (2004) 1.53
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res (2008) 1.53
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest (2015) 1.53
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
Transoral robotic surgery: supraglottic partial laryngectomy. Ann Otol Rhinol Laryngol (2007) 1.51
Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins. Laryngoscope (2012) 1.49
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol (2005) 1.45
Transoral robotic surgery alone for oropharyngeal cancer: an analysis of local control. Arch Otolaryngol Head Neck Surg (2012) 1.44
Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes. Proc Natl Acad Sci U S A (2004) 1.44
Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol (2002) 1.42
Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol (2002) 1.42
A repressive role for prohibitin in estrogen signaling. Mol Endocrinol (2007) 1.40
Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol (2005) 1.36
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A (2002) 1.35
Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci U S A (2002) 1.35
Transoral robotic surgery and human papillomavirus status: Oncologic results. Head Neck (2010) 1.33
Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol (2007) 1.32
Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev (2005) 1.32
Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends Endocrinol Metab (2008) 1.31
Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years. Otolaryngol Head Neck Surg (2009) 1.30
Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem (2002) 1.30
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell (2008) 1.29
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology (2003) 1.28
Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord (2002) 1.28
Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. Proc Natl Acad Sci U S A (2007) 1.27
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell (2008) 1.27
Transoral robotic surgery for oropharyngeal carcinoma and its impact on patient-reported quality of life and function. Head Neck (2011) 1.26
Transoral robotic surgery: does the ends justify the means? Curr Opin Otolaryngol Head Neck Surg (2009) 1.26
Unfolding the action of progesterone receptors. J Biol Chem (2003) 1.26
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol (2005) 1.25
Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1. Proc Natl Acad Sci U S A (2007) 1.25
Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol (2005) 1.25
SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci (2003) 1.24
Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol (2011) 1.23
Rush hour at the promoter: how the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription. J Steroid Biochem Mol Biol (2005) 1.23
Nuclear receptor coactivators: master regulators of human health and disease. Annu Rev Med (2013) 1.22
Absence of the steroid receptor coactivator-3 induces B-cell lymphoma. EMBO J (2006) 1.22
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22
Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Mol Cell Endocrinol (2011) 1.22
Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Mol Cell Biol (2003) 1.22
Inhibition of NK cell activity through TGF-beta 1 by down-regulation of NKG2D in a murine model of head and neck cancer. J Immunol (2005) 1.21
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol Endocrinol (2006) 1.21
Protein arginine methyltransferase 6 regulates multiple aspects of gene expression. Nucleic Acids Res (2010) 1.21
CREB-binding protein/p300 co-activation of crystallin gene expression. J Biol Chem (2002) 1.20
A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med (2012) 1.20
Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology (2005) 1.20
Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol (2006) 1.19