Published in J Biol Chem on December 16, 2003
alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons. J Biol Chem (2007) 1.17
Structural answers and persistent questions about how nicotinic receptors work. Front Biosci (2008) 0.93
Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways. Brain Res (2007) 0.89
Coupling of ionic events to protein kinase signaling cascades upon activation of alpha7 nicotinic receptor: cooperative regulation of alpha2-integrin expression and Rho kinase activity. J Biol Chem (2009) 0.89
Agrin mediates a rapid switch from electrical coupling to chemical neurotransmission during synaptogenesis. J Cell Biol (2005) 0.87
Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance. Acta Pharmacol Sin (2009) 0.83
Gene-centric analysis of serum cotinine levels in African and European American populations. Neuropsychopharmacology (2011) 0.80
PACAP/PAC1R signaling modulates acetylcholine release at neuronal nicotinic synapses. Mol Cell Neurosci (2009) 0.80
Src kinases regulate de novo actin polymerization during exocytosis in neuroendocrine chromaffin cells. PLoS One (2014) 0.78
Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Mol Pharmacol (2011) 0.78
Neuron membrane trafficking and protein kinases involved in autism and ADHD. Int J Mol Sci (2015) 0.78
Nicotinic Acetylcholine Receptor (nAChR) Dependent Chorda Tympani Taste Nerve Responses to Nicotine, Ethanol and Acetylcholine. PLoS One (2015) 0.78
Sigma receptors [σRs]: biology in normal and diseased states. J Recept Signal Transduct Res (2015) 0.78
Modulation of nicotinic receptor channels by adrenergic stimulation in rat pinealocytes. Am J Physiol Cell Physiol (2014) 0.77
Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's disease. Prion (2016) 0.75
Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res (2009) 4.68
c-Src and cooperating partners in human cancer. Cancer Cell (2004) 4.22
Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers. J Clin Pathol (2007) 2.48
Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J Neurosci (2007) 2.37
Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors. Mol Pharmacol (2004) 1.84
Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion. Cancer Res (2008) 1.82
Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation. Cancer Res (2011) 1.61
STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor. J Biol Chem (2002) 1.60
Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II. Mol Cell Biol (2004) 1.60
Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression. Cancer Res (2006) 1.59
Nicotinic alpha5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers. J Neurochem (2007) 1.57
Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer (2008) 1.54
Specific immunotherapy of experimental myasthenia gravis by a novel mechanism. Ann Neurol (2010) 1.53
Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res (2004) 1.44
Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation. J Biol Chem (2002) 1.37
Epidermal growth factor receptor translocation to the mitochondria: regulation and effect. J Biol Chem (2009) 1.36
Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice. Mol Pharmacol (2005) 1.34
Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors. J Neurosci (2003) 1.34
Ionizing radiation induces prostate cancer neuroendocrine differentiation through interplay of CREB and ATF2: implications for disease progression. Cancer Res (2008) 1.33
Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis. Oncogene (2003) 1.32
Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator. J Biol Chem (2005) 1.29
Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells. J Biol Chem (2004) 1.28
Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis. Mol Carcinog (2005) 1.27
Neuronal control of swimming behavior: comparison of vertebrate and invertebrate model systems. Prog Neurobiol (2010) 1.24
The neuroendocrine-derived peptide parathyroid hormone-related protein promotes prostate cancer cell growth by stabilizing the androgen receptor. Cancer Res (2009) 1.22
Loss of PTEN is associated with progression to androgen independence. Prostate (2006) 1.20
p190RhoGAP is cell cycle regulated and affects cytokinesis. J Cell Biol (2003) 1.18
Increased nicotinic acetylcholine receptor protein underlies chronic nicotine-induced up-regulation of nicotinic agonist binding sites in mouse brain. J Pharmacol Exp Ther (2011) 1.15
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proc Natl Acad Sci U S A (2007) 1.15
Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. J Biol Chem (2005) 1.13
Neuroendocrine cells in prostate cancer. Crit Rev Eukaryot Gene Expr (2004) 1.12
Structural determinants of alpha4beta2 nicotinic acetylcholine receptor trafficking. J Neurosci (2005) 1.10
Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the alpha6 subunit. Mol Pharmacol (2004) 1.04
Detection and isolation of circulating tumor cells: principles and methods. Biotechnol Adv (2013) 1.04
Synaptic connections of starburst amacrine cells and localization of acetylcholine receptors in primate retinas. J Comp Neurol (2003) 1.04
Immunolabeling demonstrates the interdependence of mouse brain alpha4 and beta2 nicotinic acetylcholine receptor subunit expression. J Comp Neurol (2006) 1.04
Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells. Cancer Res (2007) 1.03
Associations between childhood refraction and parental smoking. Invest Ophthalmol Vis Sci (2006) 1.02
The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. FASEB J (2004) 1.02
The unique α4+/-α4 agonist binding site in (α4)3(β2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (α4)2(β2)3 subtype. J Pharmacol Exp Ther (2013) 1.01
Raft-dependent endocytosis of autocrine motility factor is phosphatidylinositol 3-kinase-dependent in breast carcinoma cells. J Biol Chem (2007) 1.00
Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models. Carcinogenesis (2012) 0.98
Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines. Clin Nutr (2007) 0.97
p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells. Exp Cell Res (2009) 0.95
Knockdown of scavenger receptor class B type I reduces prostate specific antigen secretion and viability of prostate cancer cells. Prostate (2011) 0.95
Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells. Mol Endocrinol (2005) 0.95
Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models. Breast Cancer Res (2014) 0.94
Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis. Cell Cycle (2008) 0.93
Presynaptic targeting of alpha4beta 2 nicotinic acetylcholine receptors is regulated by neurexin-1beta. J Biol Chem (2009) 0.93
Identification of Redeye, a new sleep-regulating protein whose expression is modulated by sleep amount. Elife (2014) 0.93
Pharmacological and immunochemical characterization of alpha2* nicotinic acetylcholine receptors (nAChRs) in mouse brain. Acta Pharmacol Sin (2009) 0.92
Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine Fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells. Cancer Res (2006) 0.92
Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis. J Biol Chem (2010) 0.91
PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15. Mol Cell Biol (2008) 0.90
Inhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation. J Thorac Cardiovasc Surg (2002) 0.90
Comprehensive expression analysis of L-dopa decarboxylase and established neuroendocrine markers in neoadjuvant hormone-treated versus varying Gleason grade prostate tumors. Hum Pathol (2006) 0.90
In vitro and in vivo histone deacetylase inhibitor therapy with vorinostat and paclitaxel in ovarian cancer models: does timing matter? Gynecol Oncol (2010) 0.89
Alcohol modulation of neuronal nicotinic acetylcholine receptors is alpha subunit dependent. Alcohol Clin Exp Res (2002) 0.89
The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism. J Biol Chem (2004) 0.88
Regulation of global gene expression in the bone marrow microenvironment by androgen: androgen ablation increases insulin-like growth factor binding protein-5 expression. Prostate (2007) 0.88
TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling. Int J Cancer (2013) 0.88
Local-distributed integration by a novel neuron ensures rapid initiation of animal locomotion. J Neurophysiol (2010) 0.87
In vitro inhibition of adrenal catecholamine secretion by steroidal metabolites of ginseng saponins. Biochem Pharmacol (2003) 0.87
Nicotinic acetylcholine receptor subunits in rhesus monkey retina. Invest Ophthalmol Vis Sci (2008) 0.87
Antisense oligonucleotide targeting of insulin-like growth factor-1 receptor (IGF-1R) in prostate cancer. Prostate (2010) 0.83
Mutations of cytosolic loop residues impair assembly and maturation of alpha7 nicotinic acetylcholine receptors. J Neurochem (2009) 0.83
Relaxin stimulates leukocyte adhesion and migration through a relaxin receptor LGR7-dependent mechanism. J Biol Chem (2005) 0.83
Effect of simvastatin on castration-resistant prostate cancer cells. Lipids Health Dis (2014) 0.82
Carbidopa abrogates L-dopa decarboxylase coactivation of the androgen receptor and delays prostate tumor progression. Int J Cancer (2011) 0.82
Neuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling. Prostate (2012) 0.81
The Tumor Suppressor, p190RhoGAP, Differentially Initiates Apoptosis and Confers Docetaxel Sensitivity to Breast Cancer Cells. Genes Cancer (2011) 0.81
CaMKII-γ mediates phosphorylation of BAD at Ser170 to regulate cytokine-dependent survival and proliferation. Biochem J (2012) 0.81
Relaxin promotes clustering, migration, and activation states of mononuclear myelocytic cells. Ann N Y Acad Sci (2009) 0.81
Positive feedback loops sustain repeating bursts in neuronal circuits. J Biol Phys (2010) 0.80
Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacol Biochem Behav (2012) 0.80
Identification of cholinoceptive glycinergic neurons in the mammalian retina. J Comp Neurol (2003) 0.80
MMTV-EGF receptor transgene promotes preneoplastic conversion of multiple steroid hormone-responsive tissues. J Cell Biochem (2008) 0.79
Specialized brain regions and sensory inputs that control locomotion in leeches. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2011) 0.79
Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice. Genomics Proteomics Bioinformatics (2013) 0.79
Mechnisms underlying different facilitation forms at the lobster neuromuscular synapse. Brain Res (2004) 0.78
The human papillomavirus E7 proteins associate with p190RhoGAP and alter its function. J Virol (2014) 0.78
Human prostate cancer xenografts in lit/lit mice exhibit reduced growth and androgen-independent progression. Prostate (2010) 0.77
Expression of alpha 4 and alpha 7 nicotinic receptors in the brainstem of female rabbits after coitus. Brain Res (2004) 0.77
LKB1 and Src: antagonistic regulators of tumor growth and metastasis. Cancer Cell (2010) 0.76
A mechanistic study of the effect of doxorubicin/adriamycin on the estrogen response in a breast cancer model. Oncology (2012) 0.76
Demonstration of upregulated H2 relaxin mRNA expression during neuroendocrine differentiation of LNCaP prostate cancer cells and production of biologically active mammalian recombinant 6 histidine-tagged H2 relaxin. Ann N Y Acad Sci (2005) 0.76
The impact of diet and micronutrient supplements on the expression of neuroendocrine markers in murine Lady transgenic prostate. Prostate (2008) 0.76
A taxonomic framework for assessing governance challenges and environmental effects of integrated food-energy systems. Environ Sci Technol (2015) 0.75
Nicotine and alpha-bungarotoxin modify the dendritic growth of cholinoceptive neurons in the developing chick tectum. Brain Res Dev Brain Res (2003) 0.75