Published in Cancer Res on October 15, 2008
Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol (2009) 2.41
Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility. Curr Opin Cell Biol (2009) 1.99
Cowpea mosaic virus nanoparticles target surface vimentin on cancer cells. Nanomedicine (Lond) (2011) 1.49
Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem (2010) 1.43
Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. Cell Adh Migr (2012) 1.41
Caveolin-1 tumor-promoting role in human melanoma. Int J Cancer (2009) 1.23
The role of caveolin-1 in prostate cancer: clinical implications. Prostate Cancer Prostatic Dis (2009) 1.20
Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition. Mol Biol Cell (2012) 1.16
Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer. Cancer Res (2010) 1.14
Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol (2012) 1.13
CpG island shore methylation regulates caveolin-1 expression in breast cancer. Oncogene (2012) 1.12
Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells. BMC Cancer (2009) 1.11
Listeria monocytogenes internalin and E-cadherin: from bench to bedside. Cold Spring Harb Perspect Biol (2009) 1.08
Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion. Breast Cancer Res (2011) 1.07
Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27. J Biol Chem (2009) 1.06
Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation. Mol Biol Cell (2009) 1.04
PIPKIγ regulates focal adhesion dynamics and colon cancer cell invasion. PLoS One (2011) 1.04
Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation. J Cell Biol (2012) 1.03
KiSS1 suppresses TNFalpha-induced breast cancer cell invasion via an inhibition of RhoA-mediated NF-kappaB activation. J Cell Biochem (2009) 1.03
Association of genetic variation in mitotic kinases with breast cancer risk. Breast Cancer Res Treat (2009) 1.02
Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol (2010) 1.01
Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize. Mol Cancer Res (2010) 1.01
Bidirectional control of the inner dynamics of focal adhesions promotes cell migration. Cell Adh Migr (2009) 1.00
Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae. J Cell Mol Med (2009) 0.99
Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer. Trends Biotechnol (2015) 0.99
The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness. Cell Cycle (2013) 0.99
Cavin fever: regulating caveolae. Nat Cell Biol (2009) 0.98
Keratin 8/18 modulation of protein kinase C-mediated integrin-dependent adhesion and migration of liver epithelial cells. Mol Biol Cell (2010) 0.98
Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells. J Biomed Sci (2012) 0.95
Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. PLoS One (2012) 0.93
Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events. J Cell Sci (2010) 0.93
Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis. Int J Cancer (2013) 0.92
Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness. Mol Cell Proteomics (2013) 0.91
Lipid raft association restricts CD44-ezrin interaction and promotion of breast cancer cell migration. Am J Pathol (2012) 0.91
Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements. PLoS Biol (2010) 0.91
Galectin-3- and phospho-caveolin-1-dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells. Mol Biol Cell (2013) 0.88
Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells. Am J Physiol Cell Physiol (2011) 0.88
A model for phospho-caveolin-1-driven turnover of focal adhesions. Cell Adh Migr (2011) 0.86
Serum caveolin-1, a biomarker of drug response and therapeutic target in prostate cancer models. Cancer Biol Ther (2012) 0.86
Src-mediated caveolin-1 phosphorylation affects the targeting of active Src to specific membrane sites. Mol Biol Cell (2013) 0.85
Enhanced live cell imaging via photonic crystal enhanced fluorescence microscopy. Analyst (2014) 0.85
A role for KAI1 in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase. J Biol Chem (2010) 0.85
Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression (Review). Oncol Lett (2014) 0.84
Caveolins and lung function. Adv Exp Med Biol (2012) 0.84
Caveolin-1 as a promoter of tumour spreading: when, how, where and why. J Cell Mol Med (2013) 0.84
Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions. J Biol Chem (2008) 0.83
Tagging strategies strongly affect the fate of overexpressed caveolin-1. Traffic (2015) 0.83
Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits tumor metastasis in mouse melanoma through suppression of the Rho/ROCK pathway. Clin Exp Metastasis (2010) 0.83
Galectin-3 Overrides PTRF/Cavin-1 Reduction of PC3 Prostate Cancer Cell Migration. PLoS One (2015) 0.82
Association of caveolin-1 and -2 genetic variants and post-treatment serum caveolin-1 with prostate cancer risk and outcomes. Prostate (2010) 0.82
Cyr61 as mediator of Src signaling in triple negative breast cancer cells. Oncotarget (2015) 0.82
Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression. J Pineal Res (2015) 0.82
Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma. PLoS One (2014) 0.81
Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2). PLoS One (2011) 0.79
Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities. Expert Rev Mol Med (2015) 0.78
Reciprocal activating crosstalk between c-Met and caveolin 1 promotes invasive phenotype in hepatocellular carcinoma. PLoS One (2014) 0.78
Raft-dependent endocytosis of autocrine motility factor/phosphoglucose isomerase: a potential drug delivery route for tumor cells. PLoS One (2008) 0.78
Caveolin-1 P132L mutation in human cancers: 1 CAVeat to be voiced. J Mol Diagn (2010) 0.76
Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis. Biochem Biophys Res Commun (2013) 0.76
Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo. Oncotarget (2016) 0.76
Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. Br J Anaesth (2015) 0.75
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis. Oncotarget (2016) 0.75
Quantitative Imaging of Cell Membrane-associated Effective Mass Density Using Photonic Crystal Enhanced Microscopy (PCEM). Prog Quantum Electron (2016) 0.75
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells. BMC Cancer (2015) 0.75
Prognostic value of caveolin-1 in genitourinary cancer: a meta-analysis. Int J Clin Exp Med (2015) 0.75
MiR-199a/b-5p inhibits hepatocellular carcinoma progression by post-transcriptionally suppressing ROCK1. Oncotarget (2017) 0.75
The phospho-caveolin-1 scaffolding domain dampens force fluctuations in focal adhesions and promotes cancer cell migration. Mol Biol Cell (2017) 0.75
Sensing of micropillars by osteoblasts involves complex intracellular signaling. J Mater Sci Mater Med (2017) 0.75
The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells. Oncogene (2017) 0.75
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat Methods (2007) 45.04
Circos: an information aesthetic for comparative genomics. Genome Res (2009) 40.02
Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol (2009) 22.22
The Genome sequence of the SARS-associated coronavirus. Science (2003) 16.68
The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature (2012) 11.91
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet (2010) 10.97
Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst (2009) 10.91
De novo assembly and analysis of RNA-seq data. Nat Methods (2010) 9.69
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med (2010) 8.74
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res (2008) 7.39
Ovarian carcinoma subtypes are different diseases: implications for biomarker studies. PLoS Med (2008) 5.19
Alternative expression analysis by RNA sequencing. Nat Methods (2010) 5.02
Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res (2009) 4.68
A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clin Cancer Res (2010) 4.61
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep (2013) 3.85
Sequence biases in large scale gene expression profiling data. Nucleic Acids Res (2006) 3.83
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science (2004) 3.73
Systematic analysis of breast cancer morphology uncovers stromal features associated with survival. Sci Transl Med (2011) 3.68
High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. PLoS Biol (2007) 3.22
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature (2011) 3.22
IslandPath: aiding detection of genomic islands in prokaryotes. Bioinformatics (2003) 3.02
De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data. Genome Biol (2009) 2.99
Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL). Blood (2005) 2.69
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol (2010) 2.60
Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers. J Clin Pathol (2007) 2.48
Modeling precision treatment of breast cancer. Genome Biol (2013) 2.42
Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol (2009) 2.41
Metabolism, cell surface organization, and disease. Cell (2009) 2.41
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res (2008) 2.37
The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. Genes Dev (2007) 2.34
DGIdb: mining the druggable genome. Nat Methods (2013) 2.26
Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. PLoS One (2009) 2.20
CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer. Breast Cancer Res (2012) 2.11
Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers. J Clin Oncol (2006) 2.11
Cost-effectiveness of using a molecular diagnostic test to improve preoperative diagnosis of thyroid cancer. Value Health (2012) 2.06
Caveolin-1 in tumor progression: the good, the bad and the ugly. Cancer Metastasis Rev (2008) 2.05
A multi-institutional evaluation of active surveillance for low risk prostate cancer. J Urol (2009) 1.97
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas. J Pathol (2011) 1.91
Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement. Am J Surg Pathol (2012) 1.83
Plasma membrane domain organization regulates EGFR signaling in tumor cells. J Cell Biol (2007) 1.82
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res (2011) 1.76
Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. Cancer Res (2010) 1.75
Automated quantitative analysis of estrogen receptor expression in breast carcinoma does not differ from expert pathologist scoring: a tissue microarray study of 3,484 cases. Breast Cancer Res Treat (2007) 1.75
Lipid rafts, caveolae, and their endocytosis. Int Rev Cell Mol Biol (2010) 1.73
Meta-analysis of colorectal cancer gene expression profiling studies identifies consistently reported candidate biomarkers. Cancer Epidemiol Biomarkers Prev (2008) 1.72
Distinct caveolae-mediated endocytic pathways target the Golgi apparatus and the endoplasmic reticulum. J Cell Sci (2003) 1.71
Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum. J Biol Chem (2001) 1.66
Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE. BMC Genomics (2009) 1.63
Whole-genome profiling of mutagenesis in Caenorhabditis elegans. Genetics (2010) 1.62
Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression. Cancer Res (2006) 1.59
Glycosylation, galectins and cellular signaling. Curr Opin Cell Biol (2011) 1.59
Galectin binding to Mgat5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells. Mol Cell Biol (2006) 1.57
Progesterone receptor is a significant factor associated with clinical outcomes and effect of adjuvant tamoxifen therapy in breast cancer patients. Breast Cancer Res Treat (2009) 1.55
Proteomic analysis of the secretome of Leishmania donovani. Genome Biol (2008) 1.54
Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer (2008) 1.54
Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1. J Cell Biol (2008) 1.52
A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen. Clin Cancer Res (2012) 1.52
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. Am J Hum Genet (2013) 1.51
Adaptive regulation at the cell surface by N-glycosylation. Traffic (2009) 1.50
Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen. Proc Natl Acad Sci U S A (2011) 1.50
Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial. Clin Cancer Res (2012) 1.47
Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major forest pest. Genome Biol (2013) 1.46
Basal breast cancer molecular subtype predicts for lower incidence of axillary lymph node metastases in primary breast cancer. Clin Breast Cancer (2008) 1.45
Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res (2004) 1.44
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer. Proc Natl Acad Sci U S A (2009) 1.42
ESR1 gene amplification in breast cancer: a common phenomenon? Nat Genet (2008) 1.33
Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis. Oncogene (2003) 1.32
BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics (2012) 1.31
Diagnosis of ovarian carcinoma cell type is highly reproducible: a transcanadian study. Am J Surg Pathol (2010) 1.29
Systematic recovery and analysis of full-ORF human cDNA clones. Genome Res (2004) 1.28
Text-mining assisted regulatory annotation. Genome Biol (2008) 1.26
Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes. Breast Cancer Res (2008) 1.25
Upregulation of the tissue inhibitor of metalloproteinase-1 protein is associated with progression of human non-small-cell lung cancer. J Clin Oncol (2004) 1.23
Synaptojanin 2 functions at an early step of clathrin-mediated endocytosis. Curr Biol (2003) 1.23
ALEXA: a microarray design platform for alternative expression analysis. Nat Methods (2008) 1.23
A Ki67/BCL2 index based on immunohistochemistry is highly prognostic in ER-positive breast cancer. J Pathol (2011) 1.23
Optimal immunohistochemical markers for distinguishing lung adenocarcinomas from squamous cell carcinomas in small tumor samples. Am J Surg Pathol (2010) 1.22
Loss of PTEN is associated with progression to androgen independence. Prostate (2006) 1.20
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. BMC Cancer (2012) 1.18
FOXA1 is an independent prognostic marker for ER-positive breast cancer. Breast Cancer Res Treat (2011) 1.17
Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis. BMC Cancer (2009) 1.14
Ganglioside GM1 levels are a determinant of the extent of caveolae/raft-dependent endocytosis of cholera toxin to the Golgi apparatus. J Cell Sci (2004) 1.14
Diagnostic utility of galectin-3 in thyroid cancer. Am J Pathol (2010) 1.14
A survey of genomic properties for the detection of regulatory polymorphisms. PLoS Comput Biol (2007) 1.14
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer. Breast Cancer Res (2010) 1.14
Transcriptome and full-length cDNA resources for the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major insect pest of pine forests. Insect Biochem Mol Biol (2012) 1.13
Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment. Ann Surg Oncol (2006) 1.13
Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. J Biol Chem (2005) 1.13
Fluid flows and forces in development: functions, features and biophysical principles. Development (2012) 1.12