Published in Mol Gen Genet on January 17, 1978
Mechanisms of microbial resistance and detoxification of mercury and organomercury compounds: physiological, biochemical, and genetic analyses. Microbiol Rev (1984) 2.97
Preparation of a DNA gene probe for detection of mercury resistance genes in gram-negative bacterial communities. Appl Environ Microbiol (1985) 2.52
Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes. Proc Natl Acad Sci U S A (1984) 2.45
Cloning of replication, incompatibility, and stability functions of R plasmid NR1. J Bacteriol (1980) 2.40
Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1. J Bacteriol (1979) 2.33
Amikacin resistance mediated by multiresistance transposon Tn2424. J Bacteriol (1983) 2.15
Tn5 insertion mutations in the mercuric ion resistance genes derived from plasmid R100. J Bacteriol (1983) 1.94
Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1. J Bacteriol (1979) 1.90
Genetic and physical map of plasmid NR1: comparison with other IncFII antibiotic resistance plasmids. Microbiol Rev (1988) 1.65
Polypeptides encoded by the mer operon. J Bacteriol (1982) 1.65
Characterization of Tn2411 and Tn2410, two transposons derived from R-plasmid R1767 and related to Tn2603 and Tn21. J Bacteriol (1983) 1.57
Biochemical and immunological characterization of an R plasmid-encoded protein with properties resembling those of major cellular outer membrane proteins. J Bacteriol (1980) 1.45
Gene copy number effects in the mer operon of plasmid NR1. J Bacteriol (1979) 1.39
Nucleotide sequence analysis of the complement resistance gene from plasmid R100. J Bacteriol (1982) 1.38
Cointegrate formation between homologous plasmids in Escherichia coli. J Bacteriol (1982) 1.30
The incompatibility product of IncFII R plasmid NR1 controls gene expression in the plasmid replication region. J Bacteriol (1982) 1.28
Dissection of the r-determinant of the plasmid R100.1: the sequence at the extremities of Tn21. Nucleic Acids Res (1981) 1.28
Wide-host-range plasmids function in the genus thiobacillus. Appl Environ Microbiol (1983) 1.25
Properties of lambda transducing bacteriophages carrying R100 plasmid DNA: mercury resistance genes. J Bacteriol (1978) 1.21
Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100. J Bacteriol (1982) 1.20
Rosanilins: indicator dyes for chloramphenicol-resistant enterobacteria containing chloramphenicol acetyltransferase. J Bacteriol (1982) 1.19
Resistance to fusidic acid in Escherichia coli mediated by the type I variant of chloramphenicol acetyltransferase. A plasmid-encoded mechanism involving antibiotic binding. Biochem J (1983) 1.18
Some mercurial resistance plasmids from different incompatibility groups specify merR regulatory functions that both repress and induce the mer operon of plasmid R100. J Bacteriol (1985) 1.14
Homologous sequences other than insertion elements can serve as recombination sites in plasmid drug resistance gene amplification. J Bacteriol (1983) 1.13
Transition of deletion mutants of the composite resistance plasmid NR1 in Escherichia coli and Salmonella typhimurium. J Bacteriol (1984) 1.12
Cloning, mapping, and sequencing of plasmid R100 traM and finP genes. J Bacteriol (1986) 1.11
Regulation of transcription of the repA1 gene in the replication control region of IncFII plasmid NR1 by gene dosage of the repA2 transcription repressor protein. J Bacteriol (1985) 1.07
Deletions in the r-determinant mer region of plasmid R100-1 selected for loss of mercury hypersensitivy. J Bacteriol (1979) 1.04
Recombination sites in plasmid drug resistance gene amplification. J Bacteriol (1985) 0.99
Chloramphenicol acetyltransferase may confer resistance to fusidic acid by sequestering the drug. J Bacteriol (1983) 0.93
Recombination between two IS/s flanking the r-determinant of R100-1: involvement of dor and recA gene functions in Salmonella typhimurium. J Bacteriol (1982) 0.92
Effect of gene amplification on mercuric ion reduction activity of Escherichia coli. Appl Environ Microbiol (1991) 0.89
Transcription of the stability operon of IncFII plasmid NR1. J Bacteriol (1991) 0.86
Salmonella typhimurium LT2 mutation affecting the deletion of resistance determinants on R plasmids. J Bacteriol (1980) 0.84
Incompatibility mutants of IncFII plasmid NR1 and their effect on replication control. J Bacteriol (1985) 0.81
Asymmetric transcription of R plasmid NR1 in Proteus mirabilis. J Bacteriol (1979) 0.75
dnaB analog function associated with plasmid R100drd-1. J Bacteriol (1983) 0.75
A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science (1995) 15.20
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell (1995) 9.82
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci U S A (1994) 8.92
DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev (1998) 7.78
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc Natl Acad Sci U S A (1994) 6.93
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (1989) 4.79
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci U S A (1989) 4.17
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science (1989) 4.08
Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis. J Cell Biol (1999) 3.77
Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet (2001) 3.51
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc Natl Acad Sci U S A (1991) 2.93
EcoRI restriction endonuclease map of the composite R plasmid NR1. J Bacteriol (1976) 2.90
cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat Cell Biol (2000) 2.83
Functional genomics of Escherichia coli in Japan. Res Microbiol (2000) 2.59
Frequency of choroidal abnormalities in neurofibromatosis type 1. Lancet (2000) 2.48
Cloning of replication, incompatibility, and stability functions of R plasmid NR1. J Bacteriol (1980) 2.40
Restriction endonuclease analysis of ribosomal DNA from Saccharomyces cerevisiae. Mol Gen Genet (1976) 2.34
Method for obtaining more-accurate covalently closed circular plasmid-to-chromosome ratios from bacterial lysates by dye-buoyant density centrifugation. J Bacteriol (1977) 2.27
Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med (1997) 2.17
Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion. J Biol Chem (2001) 2.14
Comparison of haemodynamic responses to tracheal intubation using the Airway Scope(®) and Macintosh laryngoscope in normotensive and hypertensive patients. Anaesthesia (2011) 2.13
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem (1999) 2.12
Bacteriophage lambda carrying the Escherichia coli chromosomal region of the replication origin. Proc Natl Acad Sci U S A (1978) 2.11
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J (1994) 2.09
Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. Thorax (1998) 2.04
Body fat mass and lean mass as predictors of survival in hemodialysis patients. Kidney Int (2006) 2.04
toxB gene on pO157 of enterohemorrhagic Escherichia coli O157:H7 is required for full epithelial cell adherence phenotype. Infect Immun (2001) 2.04
Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation. J Biol Chem (2000) 2.04
Two novel heat shock genes encoding proteins produced in response to heterologous protein expression in Escherichia coli. J Bacteriol (1992) 1.98
The genetics of alkaline phosphatase formation in Bacillus subtilis. Genetics (1965) 1.96
The differentiation of anxiety and depression by rating scales. Acta Psychiatr Scand (1988) 1.95
Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J (1993) 1.92
Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1. J Bacteriol (1979) 1.90
Organization of the lexA gene of Escherichia coli and nucleotide sequence of the regulatory region. Nucleic Acids Res (1981) 1.90
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway. J Cell Biol (2001) 1.85
Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science (2001) 1.84
Transition of the R factor NR1 and Proteus mirabilis: level of drug resistance of nontransitioned and transitioned cells. J Bacteriol (1975) 1.73
Control of cell division by sex factor F in Escherichia coli. I. The 42.84-43.6 F segment couples cell division of the host bacteria with replication of plasmid DNA. J Mol Biol (1984) 1.73
Construction and restriction endonuclease mapping of hybrid plasmids containing Saccharomyces cerevisiae ribosomal DNA. Mol Gen Genet (1977) 1.70
Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability. Oncogene (1999) 1.70
Properties of a Saccharomyces cerevisiae mtDNA segment conferring high-frequency yeast transformation. Proc Natl Acad Sci U S A (1982) 1.69
Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor. Cell (1994) 1.67
Genetic and physical map of plasmid NR1: comparison with other IncFII antibiotic resistance plasmids. Microbiol Rev (1988) 1.65
Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets. Biochem Mol Med (1997) 1.63
The nucleotide sequence surrounding the promoter region of colicin E1 gene. Gene (1981) 1.63
Generation of miniplasmids from copy number mutants of the R plasmid NR1. J Bacteriol (1977) 1.62
IncFII plasmid incompatibility product and its target are both RNA transcripts. J Bacteriol (1984) 1.61
Expression cloning of a human dual-specificity phosphatase. Proc Natl Acad Sci U S A (1992) 1.59
Copy-number mutants of the plasmid carrying the replication origin of the Escherichia coli chromosome: evidence for a control region of replication. Proc Natl Acad Sci U S A (1980) 1.58
Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics. Nat Genet (1996) 1.58
Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice. Circ Res (2001) 1.56
Western blot (immunoblot) assay of small, round-structured virus associated with an acute gastroenteritis outbreak in Tokyo. J Clin Microbiol (1989) 1.55
The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases. Proc Natl Acad Sci U S A (1990) 1.54
Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group. Am J Hum Genet (1997) 1.52
Molecular basis of electrocardiographic ST-segment elevation. Circ Res (2000) 1.51
Organization of unc gene cluster of Escherichia coli coding for proton-translocating ATPase of oxidative phosphorylation. Proc Natl Acad Sci U S A (1980) 1.51
Loss of genes on the long arm of chromosome 22 in human meningiomas. Mol Biol Med (1988) 1.50
Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA. Oncogene (2006) 1.49
A pilot case-control study on the alveolar bone density measurement in risk assessment for bisphosphonate-related osteonecrosis of the jaw. Osteoporos Int (2009) 1.48
Alzheimer's disease and DLST genotype. Lancet (1997) 1.48
Primary structure of the human fgr proto-oncogene product p55c-fgr. Mol Cell Biol (1988) 1.48
Control of cell division by sex factor F in Escherichia coli. II. Identification of genes for inhibitor protein and trigger protein on the 42.84-43.6 F segment. J Mol Biol (1984) 1.48
Transition of R factor NR1 in Proteus mirabilis: molecular structure and replication of NR1 deoxyribonucleic acid. J Bacteriol (1975) 1.47
Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A (2001) 1.46
Cloning and physical mapping of the dnaA region of the Escherichia coli chromosome. J Bacteriol (1979) 1.46
Nucleotide sequence of the phoS gene, the structural gene for the phosphate-binding protein of Escherichia coli. J Bacteriol (1984) 1.45
Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure. Kidney Int (1999) 1.45
A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map. DNA Res (1996) 1.45
Two origins of replication in composite R plasmid DNA. Nature (1976) 1.43
Antigenic characterization of small, round-structured viruses by immune electron microscopy. J Clin Microbiol (1990) 1.41
A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. DNA Res (1996) 1.41
Comparison of the myotonic dystrophy associated CTG repeat in European and Japanese populations. J Med Genet (1992) 1.41
Hanshin-Awaji earthquake and acute myocardial infarction. Lancet (1995) 1.40
Central diabetes insipidus associated with a missense mutation in the arginine vasopressin gene that replaces Ala at the carboxyterminus of the signal peptide with Thr. Intern Med (1998) 1.40
High-resolution separation of PCR product and gene diagnosis by capillary gel electrophoresis. Biomed Chromatogr (1995) 1.39
Dating of a fault by electron spin resonance on intrafault materials. Science (1982) 1.39
Gene copy number effects in the mer operon of plasmid NR1. J Bacteriol (1979) 1.39
Intravenous co-infusion of adenosine and norepinephrine preconditions the heart without adverse hemodynamic effects. J Thorac Cardiovasc Surg (1997) 1.38
Low doses of oral dexamethasone for hormone-refractory prostate carcinoma. Cancer (2000) 1.38
Specialized transducing phage lambda carrying the genes for coupling factor of oxidative phosphorylation of Escherichia coli: increased synthesis of coupling factor on induction of prophage lambda asn. Proc Natl Acad Sci U S A (1979) 1.37
Transcription of the uvrD gene of Escherichia coli is controlled by the lexA repressor and by attenuation. Nucleic Acids Res (1983) 1.36
Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors. Cancer Res (1991) 1.34
Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features. DNA Res (1997) 1.33
Prevalence of small round structured virus infections in acute gastroenteritis outbreaks in Tokyo. Microbiol Immunol (1989) 1.33
Genetic organization and nucleotide sequence of the stability locus of IncFII plasmid NR1. J Mol Biol (1988) 1.32
A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. DNA Res (1996) 1.31
Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers. Am J Hum Genet (1996) 1.31
Cloning of human immunoglobulin epsilon chain genes: evidence for multiple C epsilon genes. Proc Natl Acad Sci U S A (1982) 1.30
Cointegrate formation between homologous plasmids in Escherichia coli. J Bacteriol (1982) 1.30
The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells. Proc Natl Acad Sci U S A (1991) 1.29
Expansion of unstable DNA region in Japanese myotonic dystrophy patients. Lancet (1992) 1.29
The incompatibility product of IncFII R plasmid NR1 controls gene expression in the plasmid replication region. J Bacteriol (1982) 1.28
Transcription of the replication control region of the IncFII R-plasmid NR1 in vitro and in vivo. J Mol Biol (1985) 1.28