Published in J Mol Biol on January 16, 2004
Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet (2006) 3.38
Molecular identification of a malaria merozoite surface sheddase. PLoS Pathog (2005) 2.06
An IgG-like domain in the minor pilin GBS52 of Streptococcus agalactiae mediates lung epithelial cell adhesion. Structure (2007) 1.64
Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications. Proc Natl Acad Sci U S A (2005) 1.54
Biotechnological Aspects and Perspective of Microbial Keratinase Production. Biomed Res Int (2015) 0.94
Functional insight into the C-terminal extension of halolysin SptA from haloarchaeon Natrinema sp. J7. PLoS One (2011) 0.87
Insights into the maturation of hyperthermophilic pyrolysin and the roles of its N-terminal propeptide and long C-terminal extension. Appl Environ Microbiol (2012) 0.86
Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism. Proc Natl Acad Sci U S A (2011) 0.82
Metagenomic Analysis of Hot Springs in Central India Reveals Hydrocarbon Degrading Thermophiles and Pathways Essential for Survival in Extreme Environments. Front Microbiol (2017) 0.81
Enhancement of the catalytic efficiency and thermostability of Stenotrophomonas sp. keratinase KerSMD by domain exchange with KerSMF. Microb Biotechnol (2015) 0.77
Cloning and expression of islandisin, a new thermostable subtilisin from Fervidobacterium islandicum, in Escherichia coli. Appl Environ Microbiol (2005) 0.76
Purification and Characterization of a Keratinase from a Feather-Degrading Fungus, Aspergillus flavus Strain K-03. Mycobiology (2007) 0.75
Molecular Modeling of Cloned Bacillus subtilis Keratinase and Its Insinuation in Psoriasis Treatment Using Docking Studies. Indian J Microbiol (2017) 0.75
Enterotypes of the human gut microbiome. Nature (2011) 24.36
Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med (2013) 20.65
Small CRISPR RNAs guide antiviral defense in prokaryotes. Science (2008) 17.79
Evolution and classification of the CRISPR-Cas systems. Nat Rev Microbiol (2011) 17.11
Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A (2003) 8.40
Richness of human gut microbiome correlates with metabolic markers. Nature (2013) 6.93
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence. Proc Natl Acad Sci U S A (2011) 6.89
Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol (2002) 6.74
Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology (2012) 6.04
Structural basis for CRISPR RNA-guided DNA recognition by Cascade. Nat Struct Mol Biol (2011) 6.02
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A (2013) 5.88
Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One (2009) 4.93
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3. Mol Cell (2012) 4.84
Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein. Proc Natl Acad Sci U S A (2009) 4.61
Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol (2004) 4.05
Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: effective recovery of bacterial and archaeal DNA using mechanical cell lysis. J Microbiol Methods (2010) 3.58
Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ Microbiol (2009) 3.57
Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA. Appl Environ Microbiol (2002) 3.43
Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women. Gut (2012) 3.09
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine. Nature (2002) 3.05
Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second. Opt Express (2010) 3.04
Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head. Invest Ophthalmol Vis Sci (2008) 3.01
Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol (2007) 3.00
Colonic microbiota signatures across five northern European countries. Appl Environ Microbiol (2005) 2.98
The genome sequence of the extreme thermophile Thermus thermophilus. Nat Biotechnol (2004) 2.95
Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology (2011) 2.79
A microbial world within us. Mol Microbiol (2006) 2.76
Fighting fruit flies: a model system for the study of aggression. Proc Natl Acad Sci U S A (2002) 2.66
S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. Proc Natl Acad Sci U S A (2008) 2.65
Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser. Opt Express (2011) 2.62
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes. Biol Chem (2011) 2.59
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity. Annu Rev Genet (2012) 2.56
Anaerobic microbial dehalogenation. Annu Rev Microbiol (2004) 2.51
Metagenomic species profiling using universal phylogenetic marker genes. Nat Methods (2013) 2.51
Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes (2011) 2.46
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nat Struct Biol (2003) 2.42
Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance. Proc Natl Acad Sci U S A (2009) 2.29
Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography. Opt Express (2008) 2.24
Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc Natl Acad Sci U S A (2011) 2.22
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism. Nature (2008) 2.22
Analysis of growth of Lactobacillus plantarum WCFS1 on a complex medium using a genome-scale metabolic model. J Biol Chem (2006) 2.17
The Lrp family of transcriptional regulators. Mol Microbiol (2003) 2.15
The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract. Appl Environ Microbiol (2007) 2.09
Identification of Lactobacillus plantarum genes that are induced in the gastrointestinal tract of mice. J Bacteriol (2004) 2.06
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry. Anal Chem (2006) 2.06
Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range. Opt Express (2009) 2.03
Exploring Lactobacillus plantarum genome diversity by using microarrays. J Bacteriol (2005) 2.02
Initial mutations direct alternative pathways of protein evolution. PLoS Genet (2011) 2.01
HTRA proteases: regulated proteolysis in protein quality control. Nat Rev Mol Cell Biol (2011) 2.01
Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Proc Natl Acad Sci U S A (2004) 1.99
Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. J Am Chem Soc (2006) 1.96
The micro-Petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms. Proc Natl Acad Sci U S A (2007) 1.94
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation. Nature (2003) 1.92
The genome of Akkermansia muciniphila, a dedicated intestinal mucin degrader, and its use in exploring intestinal metagenomes. PLoS One (2011) 1.90
Probiotic and other functional microbes: from markets to mechanisms. Curr Opin Biotechnol (2005) 1.89
Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. PLoS One (2011) 1.88
Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus. Appl Environ Microbiol (2008) 1.85
Biodiversity-based identification and functional characterization of the mannose-specific adhesin of Lactobacillus plantarum. J Bacteriol (2005) 1.85
Quantification of uncultured Ruminococcus obeum-like bacteria in human fecal samples by fluorescent in situ hybridization and flow cytometry using 16S rRNA-targeted probes. Appl Environ Microbiol (2002) 1.82
The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates. ISME J (2012) 1.81
Molecular machines for protein degradation. Chembiochem (2005) 1.81
Microbes inside--from diversity to function: the case of Akkermansia. ISME J (2012) 1.80
Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities. EMBO J (2002) 1.79
Development of bacterial and bifidobacterial communities in feces of newborn babies. Anaerobe (2003) 1.78
Therapeutic potential of fecal microbiota transplantation. Gastroenterology (2013) 1.78
Microarray analysis and barcoded pyrosequencing provide consistent microbial profiles depending on the source of human intestinal samples. Appl Environ Microbiol (2011) 1.76
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO J (2004) 1.75
Isolation of RNA from bacterial samples of the human gastrointestinal tract. Nat Protoc (2006) 1.75
Genetic diversity of viable, injured, and dead fecal bacteria assessed by fluorescence-activated cell sorting and 16S rRNA gene analysis. Appl Environ Microbiol (2005) 1.74
Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol (2007) 1.73
Mucosal adhesion properties of the probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED pilin subunits. Appl Environ Microbiol (2010) 1.71
Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila. Front Microbiol (2011) 1.69
Phase-sensitive optical coherence tomography at up to 370,000 lines per second using buffered Fourier domain mode-locked lasers. Opt Lett (2007) 1.69
Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment. Appl Environ Microbiol (2005) 1.69
Mucin-bacterial interactions in the human oral cavity and digestive tract. Gut Microbes (2010) 1.65
Intestinal microbiota in human health and disease: the impact of probiotics. Genes Nutr (2011) 1.63
Phylogenetic analysis of dysbiosis in ulcerative colitis during remission. Inflamm Bowel Dis (2013) 1.63
K-space linear Fourier domain mode locked laser and applications for optical coherence tomography. Opt Express (2008) 1.62
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism. Proc Natl Acad Sci U S A (2003) 1.62
An agr-like two-component regulatory system in Lactobacillus plantarum is involved in production of a novel cyclic peptide and regulation of adherence. J Bacteriol (2005) 1.61
Cell to cell communication by autoinducing peptides in gram-positive bacteria. Antonie Van Leeuwenhoek (2002) 1.61
Comparative genomics of Lactobacillus. Microb Biotechnol (2010) 1.60
The intestinal LABs. Antonie Van Leeuwenhoek (2002) 1.60
Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements. Biol Direct (2009) 1.58
Improved spectral optical coherence tomography using optical frequency comb. Opt Express (2008) 1.58
Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution. Proc Natl Acad Sci U S A (2002) 1.57
The function of our microbiota: who is out there and what do they do? Front Cell Infect Microbiol (2012) 1.54
Aggression in invertebrates. Curr Opin Neurobiol (2003) 1.53
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. Proc Natl Acad Sci U S A (2003) 1.52
Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectives. Microbiology (2010) 1.50
Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev (2007) 1.50
Identification of prebiotic fructooligosaccharide metabolism in Lactobacillus plantarum WCFS1 through microarrays. Appl Environ Microbiol (2007) 1.48
Diversity, dynamics, and activity of bacterial communities during production of an artisanal Sicilian cheese as evaluated by 16S rRNA analysis. Appl Environ Microbiol (2002) 1.48
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A (2008) 1.48
Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. Proc Natl Acad Sci U S A (2005) 1.47
NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides. J Biol Chem (2004) 1.47
RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements. Cold Spring Harb Perspect Biol (2012) 1.47