Published in Proc Natl Acad Sci U S A on September 17, 2009
The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci U S A (2010) 4.35
Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol (2010) 3.45
Microbiota-mediated colonization resistance against intestinal pathogens. Nat Rev Immunol (2013) 2.89
Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc Natl Acad Sci U S A (2011) 2.22
Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging. Proc Natl Acad Sci U S A (2010) 2.14
Complete genome sequence of the probiotic Lactobacillus rhamnosus ATCC 53103. J Bacteriol (2009) 2.12
The genome of Akkermansia muciniphila, a dedicated intestinal mucin degrader, and its use in exploring intestinal metagenomes. PLoS One (2011) 1.90
Microbes inside--from diversity to function: the case of Akkermansia. ISME J (2012) 1.80
Mucosal adhesion properties of the probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED pilin subunits. Appl Environ Microbiol (2010) 1.71
Mucin-bacterial interactions in the human oral cavity and digestive tract. Gut Microbes (2010) 1.65
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Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization. PLoS One (2010) 1.56
Analysis of the Lactobacillus casei supragenome and its influence in species evolution and lifestyle adaptation. BMC Genomics (2012) 1.42
Characterization of a probiotic-derived soluble protein which reveals a mechanism of preventive and treatment effects of probiotics on intestinal inflammatory diseases. Gut Microbes (2012) 1.40
Characterization of the SpaCBA pilus fibers in the probiotic Lactobacillus rhamnosus GG. Appl Environ Microbiol (2012) 1.39
Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions. Proc Natl Acad Sci U S A (2013) 1.36
Diversity, ecology and intestinal function of bifidobacteria. Microb Cell Fact (2014) 1.35
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Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells. Appl Environ Microbiol (2011) 1.31
Exopolysaccharides of Lactobacillus rhamnosus GG form a protective shield against innate immune factors in the intestine. Microb Biotechnol (2010) 1.30
At the crossroads of vaginal health and disease, the genome sequence of Lactobacillus iners AB-1. Proc Natl Acad Sci U S A (2010) 1.30
Comparative metaproteomics and diversity analysis of human intestinal microbiota testifies for its temporal stability and expression of core functions. PLoS One (2012) 1.28
Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features. PLoS One (2011) 1.25
Lactobacillus adhesion to mucus. Nutrients (2011) 1.22
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera. Nat Commun (2015) 1.22
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Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG. PLoS Genet (2013) 1.21
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Lactobacillus paracasei comparative genomics: towards species pan-genome definition and exploitation of diversity. PLoS One (2013) 1.18
Anti-infective activities of lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents. Clin Microbiol Rev (2014) 1.17
Genetic and biochemical characterization of the cell wall hydrolase activity of the major secreted protein of Lactobacillus rhamnosus GG. PLoS One (2012) 1.14
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A refined palate: bacterial consumption of host glycans in the gut. Glycobiology (2013) 1.11
Characterization of pro-inflammatory flagellin proteins produced by Lactobacillus ruminis and related motile Lactobacilli. PLoS One (2012) 1.09
Microbiota/host crosstalk biomarkers: regulatory response of human intestinal dendritic cells exposed to Lactobacillus extracellular encrypted peptide. PLoS One (2012) 1.07
The role of cell surface architecture of lactobacilli in host-microbe interactions in the gastrointestinal tract. Mediators Inflamm (2013) 1.07
Functional genomics of lactic acid bacteria: from food to health. Microb Cell Fact (2014) 1.06
Functional characterization of a mucus-specific LPXTG surface adhesin from probiotic Lactobacillus rhamnosus GG. Appl Environ Microbiol (2011) 1.06
Genomic adaptation of the Lactobacillus casei group. PLoS One (2013) 1.05
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Probiotics: progress toward novel therapies for intestinal diseases. Curr Opin Gastroenterol (2010) 1.05
Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer. Appl Environ Microbiol (2015) 1.05
Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution. Am J Physiol Gastrointest Liver Physiol (2013) 1.05
Comparative functional genomics of Lactobacillus spp. reveals possible mechanisms for specialization of vaginal lactobacilli to their environment. J Bacteriol (2014) 1.02
Proteomics and transcriptomics characterization of bile stress response in probiotic Lactobacillus rhamnosus GG. Mol Cell Proteomics (2010) 1.02
Functional dynamics of the gut microbiome in elderly people during probiotic consumption. MBio (2015) 0.99
Pilus biogenesis in Lactococcus lactis: molecular characterization and role in aggregation and biofilm formation. PLoS One (2012) 0.97
Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches. Front Microbiol (2015) 0.97
Functional characterization of probiotic surface layer protein-carrying Lactobacillus amylovorus strains. BMC Microbiol (2014) 0.97
Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts. Microb Cell Fact (2011) 0.95
Genome sequence of Lactobacillus rhamnosus ATCC 8530. J Bacteriol (2012) 0.95
Cell wall structure and function in lactic acid bacteria. Microb Cell Fact (2014) 0.95
The antimicrobial peptide cathelicidin protects mice from Escherichia coli O157:H7-mediated disease. PLoS One (2012) 0.94
Comparative genome analysis of Lactobacillus casei strains isolated from Actimel and Yakult products reveals marked similarities and points to a common origin. Microb Biotechnol (2013) 0.94
Functionality of sortase A in Lactococcus lactis. Appl Environ Microbiol (2010) 0.94
A comparative pan-genome perspective of niche-adaptable cell-surface protein phenotypes in Lactobacillus rhamnosus. PLoS One (2014) 0.94
Glutamine synthetase and glucose-6-phosphate isomerase are adhesive moonlighting proteins of Lactobacillus crispatus released by epithelial cathelicidin LL-37. J Bacteriol (2012) 0.94
Towards a better understanding of Lactobacillus rhamnosus GG--host interactions. Microb Cell Fact (2014) 0.93
Epithelial adhesion mediated by pilin SpaC is required for Lactobacillus rhamnosus GG-induced cellular responses. Appl Environ Microbiol (2014) 0.93
Using recombinant Lactococci as an approach to dissect the immunomodulating capacity of surface piliation in probiotic Lactobacillus rhamnosus GG. PLoS One (2013) 0.93
Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli. Microb Biotechnol (2011) 0.92
BopA does not have a major role in the adhesion of Bifidobacterium bifidum to intestinal epithelial cells, extracellular matrix proteins, and mucus. Appl Environ Microbiol (2013) 0.92
The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro. BMC Microbiol (2014) 0.92
Ability of Bifidobacterium breve to grow on different types of milk: exploring the metabolism of milk through genome analysis. Appl Environ Microbiol (2011) 0.91
Measuring kinetic dissociation/association constants between Lactococcus lactis bacteria and mucins using living cell probes. Biophys J (2011) 0.90
Genome instability in Lactobacillus rhamnosus GG. Appl Environ Microbiol (2013) 0.89
The highly autoaggregative and adhesive phenotype of the vaginal Lactobacillus plantarum strain CMPG5300 is sortase dependent. Appl Environ Microbiol (2013) 0.89
Immunoregulatory effects triggered by immunobiotic Lactobacillus jensenii TL2937 strain involve efficient phagocytosis in porcine antigen presenting cells. BMC Immunol (2016) 0.89
Comparative genome analysis of Lactobacillus rhamnosus clinical isolates from initial stages of dental pulp infection: identification of a new exopolysaccharide cluster. PLoS One (2014) 0.89
Mitis group streptococci express variable pilus islet 2 pili. PLoS One (2011) 0.88
Lactobacillus casei ferments the N-Acetylglucosamine moiety of fucosyl-α-1,3-N-acetylglucosamine and excretes L-fucose. Appl Environ Microbiol (2012) 0.88
Functional analysis of the Lactobacillus casei BL23 sortases. Appl Environ Microbiol (2012) 0.88
Genome Sequence of the Probiotic Strain Lactobacillus rhamnosus (Formerly Lactobacillus casei) LOCK900. Genome Announc (2013) 0.88
Lectin microarray reveals binding profiles of Lactobacillus casei strains in a comprehensive analysis of bacterial cell wall polysaccharides. Appl Environ Microbiol (2011) 0.87
Intestinal barrier: A gentlemen's agreement between microbiota and immunity. World J Gastrointest Pathophysiol (2014) 0.87
Phenotypical analysis of the Lactobacillus rhamnosus GG fimbrial spaFED operon: surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis. PLoS One (2014) 0.86
Impact of Lactobacillus plantarum sortase on target protein sorting, gastrointestinal persistence, and host immune response modulation. J Bacteriol (2012) 0.86
Piliation of Lactobacillus rhamnosus GG promotes adhesion, phagocytosis, and cytokine modulation in macrophages. Appl Environ Microbiol (2015) 0.86
Probiogenomics as a tool to obtain genetic insights into adaptation of probiotic bacteria to the human gut. Bioeng Bugs (2012) 0.86
Metatranscriptome analysis for insight into whole-ecosystem gene expression during spontaneous wheat and spelt sourdough fermentations. Appl Environ Microbiol (2010) 0.86
Functional identification of conserved residues involved in Lactobacillus rhamnosus strain GG sortase specificity and pilus biogenesis. J Biol Chem (2014) 0.84
Surface proteome analysis of a natural isolate of Lactococcus lactis reveals the presence of pili able to bind human intestinal epithelial cells. Mol Cell Proteomics (2013) 0.84
Functional genomics of Lactobacillus casei establishment in the gut. Proc Natl Acad Sci U S A (2014) 0.84
Nonpathogenic Lactobacillus rhamnosus activates the inflammasome and antiviral responses in human macrophages. Gut Microbes (2012) 0.84
Lactobacillus rhamnosus GG: An Updated Strategy to Use Microbial Products to Promote Health. Funct Food Rev (2012) 0.84
Catabolic flexibility of mammalian-associated lactobacilli. Microb Cell Fact (2013) 0.83
New insights into probiotic mechanisms: a harvest from functional and metagenomic studies. Gut Microbes (2012) 0.83
Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919. Genome Biol Evol (2015) 0.83
Adhesion Properties of Lactic Acid Bacteria on Intestinal Mucin. Microorganisms (2016) 0.82
Lactobacillus rhamnosus GG and its SpaC pilus adhesin modulate inflammatory responsiveness and TLR-related gene expression in the fetal human gut. Pediatr Res (2015) 0.82
Impact of genomics on the field of probiotic research: historical perspectives to modern paradigms. Antonie Van Leeuwenhoek (2014) 0.82
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model. PLoS One (2015) 0.82
Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Mol Microbiol (2012) 0.82
Growth phase-associated changes in the proteome and transcriptome of Lactobacillus rhamnosus GG in industrial-type whey medium. Microb Biotechnol (2011) 0.82
Purification, crystallization and preliminary crystallographic analysis of the SpaA backbone-pilin subunit from probiotic Lactobacillus rhamnosus GG. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.82
Influence of fermentation conditions on the surface properties and adhesion of Lactobacillus rhamnosus GG. Microb Cell Fact (2012) 0.81
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Stabilizing isopeptide bonds revealed in gram-positive bacterial pilus structure. Science (2007) 4.10
Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology (2006) 3.96
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Pili in Gram-negative and Gram-positive bacteria - structure, assembly and their role in disease. Cell Mol Life Sci (2009) 2.69
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Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance. Proc Natl Acad Sci U S A (2009) 2.29
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Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells. Am J Physiol Cell Physiol (2005) 2.07
Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut (2003) 2.00
Detecting pathogenicity islands and anomalous gene clusters by iterative discriminant analysis. FEMS Microbiol Lett (2003) 1.90
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Successful treatment of relapsing Clostridium difficile colitis with Lactobacillus GG. Lancet (1987) 1.88
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Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase. Appl Environ Microbiol (2009) 1.73
Expression of two distinct types of pili by a hospital-acquired Enterococcus faecium isolate. Microbiology (2008) 1.62
Lactobacillus bacteremia during a rapid increase in probiotic use of Lactobacillus rhamnosus GG in Finland. Clin Infect Dis (2002) 1.57
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Comparative genomics and transcriptional analysis of prophages identified in the genomes of Lactobacillus gasseri, Lactobacillus salivarius, and Lactobacillus casei. Appl Environ Microbiol (2006) 1.28
Sortase D forms the covalent bond that links BcpB to the tip of Bacillus cereus pili. J Biol Chem (2009) 1.25
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Staphylococcus aureus adheres to human intestinal mucus but can be displaced by certain lactic acid bacteria. Microbiology (2006) 1.21
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Genome sequence and characteristics of Lrm1, a prophage from industrial Lactobacillus rhamnosus strain M1. Appl Environ Microbiol (2008) 0.98
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Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology (2012) 6.04
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CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3. Mol Cell (2012) 4.84
Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol (2004) 4.05
Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov Disord (2014) 3.97
Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science (2008) 3.80
Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One (2010) 3.64
Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: effective recovery of bacterial and archaeal DNA using mechanical cell lysis. J Microbiol Methods (2010) 3.58
Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ Microbiol (2009) 3.57
Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol (2010) 3.45
Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA. Appl Environ Microbiol (2002) 3.43
Indole-3-acetic acid in microbial and microorganism-plant signaling. FEMS Microbiol Rev (2007) 3.21
Are data from different gene expression microarray platforms comparable? Genomics (2004) 3.13
Genes and molecules of lactobacilli supporting probiotic action. Microbiol Mol Biol Rev (2008) 3.12
Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women. Gut (2012) 3.09
Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol (2007) 3.00
Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am J Gastroenterol (2005) 2.99
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S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. Proc Natl Acad Sci U S A (2008) 2.65
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Metagenomic species profiling using universal phylogenetic marker genes. Nat Methods (2013) 2.51
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Flagella-driven chemotaxis towards exudate components is an important trait for tomato root colonization by Pseudomonas fluorescens. Mol Plant Microbe Interact (2002) 2.42
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Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification. World J Gastroenterol (2009) 2.39
Quorum sensing and swarming migration in bacteria. FEMS Microbiol Rev (2004) 2.38
Prevention of sports injuries: systematic review of randomized controlled trials. Arch Intern Med (2007) 2.36
Gene expression in human NAFLD. Am J Physiol Gastrointest Liver Physiol (2008) 2.33
Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance. Proc Natl Acad Sci U S A (2009) 2.29
Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc Natl Acad Sci U S A (2011) 2.22
Diversity and seasonal dynamics of bacterial community in indoor environment. BMC Microbiol (2008) 2.22
Analysis of growth of Lactobacillus plantarum WCFS1 on a complex medium using a genome-scale metabolic model. J Biol Chem (2006) 2.17
The Lrp family of transcriptional regulators. Mol Microbiol (2003) 2.15
The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract. Appl Environ Microbiol (2007) 2.09
Identification of Lactobacillus plantarum genes that are induced in the gastrointestinal tract of mice. J Bacteriol (2004) 2.06
Exploring Lactobacillus plantarum genome diversity by using microarrays. J Bacteriol (2005) 2.02
Longitudinal study of Finnish Campylobacter jejuni and C. coli isolates from humans, using multilocus sequence typing, including comparison with epidemiological data and isolates from poultry and cattle. Appl Environ Microbiol (2006) 2.01
New horizons for (p)ppGpp in bacterial and plant physiology. Trends Microbiol (2005) 2.00
Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy. J Allergy Clin Immunol (2004) 1.96
The micro-Petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms. Proc Natl Acad Sci U S A (2007) 1.94
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island. BMC Genomics (2010) 1.90
The genome of Akkermansia muciniphila, a dedicated intestinal mucin degrader, and its use in exploring intestinal metagenomes. PLoS One (2011) 1.90
Probiotic and other functional microbes: from markets to mechanisms. Curr Opin Biotechnol (2005) 1.89
Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. PLoS One (2011) 1.88
Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus. Appl Environ Microbiol (2008) 1.85
Biodiversity-based identification and functional characterization of the mannose-specific adhesin of Lactobacillus plantarum. J Bacteriol (2005) 1.85
Comparison of real-time PCR with SYBR Green I or 5'-nuclease assays and dot-blot hybridization with rDNA-targeted oligonucleotide probes in quantification of selected faecal bacteria. Microbiology (2003) 1.84
Lactobacillus bacteremia, clinical significance, and patient outcome, with special focus on probiotic L. rhamnosus GG. Clin Infect Dis (2003) 1.84
Quantification of uncultured Ruminococcus obeum-like bacteria in human fecal samples by fluorescent in situ hybridization and flow cytometry using 16S rRNA-targeted probes. Appl Environ Microbiol (2002) 1.82
The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates. ISME J (2012) 1.81
Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort. J Allergy Clin Immunol (2009) 1.80
Microbes inside--from diversity to function: the case of Akkermansia. ISME J (2012) 1.80
O-antigen structural variation: mechanisms and possible roles in animal/plant-microbe interactions. FEMS Microbiol Rev (2002) 1.79
Development of bacterial and bifidobacterial communities in feces of newborn babies. Anaerobe (2003) 1.78
Therapeutic potential of fecal microbiota transplantation. Gastroenterology (2013) 1.78
Microarray analysis and barcoded pyrosequencing provide consistent microbial profiles depending on the source of human intestinal samples. Appl Environ Microbiol (2011) 1.76
Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers. BMC Gastroenterol (2009) 1.76
Isolation of RNA from bacterial samples of the human gastrointestinal tract. Nat Protoc (2006) 1.75
Genetic diversity of viable, injured, and dead fecal bacteria assessed by fluorescence-activated cell sorting and 16S rRNA gene analysis. Appl Environ Microbiol (2005) 1.74
Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial. Pediatrics (2008) 1.74
Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase. Appl Environ Microbiol (2009) 1.73
Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol (2007) 1.73
Mucosal adhesion properties of the probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED pilin subunits. Appl Environ Microbiol (2010) 1.71
Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila. Front Microbiol (2011) 1.69
Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment. Appl Environ Microbiol (2005) 1.69
Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome--a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol (2005) 1.67
Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol (2006) 1.66
Mucin-bacterial interactions in the human oral cavity and digestive tract. Gut Microbes (2010) 1.65