Published in Nature on January 08, 2004
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol (2005) 7.44
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity (2006) 7.22
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 5.59
Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity (2007) 5.50
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell (2010) 5.28
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol (2009) 5.20
SAP-controlled T-B cell interactions underlie germinal centre formation. Nature (2008) 5.14
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med (2004) 5.08
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat Immunol (2008) 4.52
Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids. PLoS Biol (2005) 4.01
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol (2005) 4.01
HIV-infected T cells are migratory vehicles for viral dissemination. Nature (2012) 3.57
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med (2006) 3.57
Immunological mechanisms of vaccination. Nat Immunol (2011) 3.35
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J Exp Med (2004) 3.30
The functional network of ion channels in T lymphocytes. Immunol Rev (2009) 3.21
Intravital imaging. Cell (2011) 3.18
Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. J Exp Med (2005) 3.14
Functional anatomy of T cell activation and synapse formation. Annu Rev Immunol (2010) 3.01
Conduits mediate transport of low-molecular-weight antigen to lymph node follicles. Immunity (2009) 2.98
In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor. J Exp Med (2007) 2.89
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo. Nat Immunol (2005) 2.89
Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol (2008) 2.86
Stromal cell contributions to the homeostasis and functionality of the immune system. Nat Rev Immunol (2009) 2.82
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity (2011) 2.81
CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J Exp Med (2007) 2.81
CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells. J Immunol (2008) 2.69
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature (2009) 2.59
Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues. Immunity (2014) 2.58
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med (2012) 2.58
Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones. Blood (2009) 2.58
Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. J Exp Med (2005) 2.54
Directed migration of positively selected thymocytes visualized in real time. PLoS Biol (2005) 2.46
CD8(+) T cells: foot soldiers of the immune system. Immunity (2011) 2.45
Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs. Nat Immunol (2012) 2.45
Random migration precedes stable target cell interactions of tumor-infiltrating T cells. J Exp Med (2006) 2.43
Immune homeostasis enforced by co-localized effector and regulatory T cells. Nature (2015) 2.42
Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity (2011) 2.41
DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells. J Exp Med (2004) 2.38
Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med (2006) 2.30
Mechanisms and consequences of dendritic cell migration. Immunity (2008) 2.25
Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med (2005) 2.23
Dangerous liaisons at the virological synapse. J Clin Invest (2004) 2.23
In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. J Exp Med (2005) 2.21
Lymph node topology dictates T cell migration behavior. J Exp Med (2007) 2.19
HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat Rev Immunol (2012) 2.18
Fluorescence imaging beyond the ballistic regime by ultrasound pulse guided digital phase conjugation. Nat Photonics (2012) 2.18
Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response. J Exp Med (2006) 2.18
Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol (2009) 2.15
Mechanisms maintaining peripheral tolerance. Nat Immunol (2009) 2.14
Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection. J Exp Med (2005) 2.13
Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells. J Exp Med (2009) 2.10
Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory. J Immunol (2009) 2.08
CD4 T cells integrate signals delivered during successive DC encounters in vivo. J Exp Med (2005) 1.99
Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends Cell Biol (2008) 1.99
Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes. Immunity (2009) 1.96
Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell (2012) 1.95
Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization. Immunity (2006) 1.95
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells. J Exp Med (2011) 1.95
A decade of imaging cellular motility and interaction dynamics in the immune system. Science (2012) 1.94
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature (2009) 1.94
Follicular helper T cells in immunity and systemic autoimmunity. Nat Rev Rheumatol (2012) 1.89
A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J Cell Biol (2005) 1.88
Impaired lymphatic contraction associated with immunosuppression. Proc Natl Acad Sci U S A (2011) 1.88
CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation. Immunity (2012) 1.85
Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature (2011) 1.80
In situ imaging of the endogenous CD8 T cell response to infection. Science (2007) 1.78
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J Exp Med (2011) 1.78
T cell receptor signalling networks: branched, diversified and bounded. Nat Rev Immunol (2013) 1.77
In vivo imaging in cancer. Cold Spring Harb Perspect Biol (2010) 1.76
Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone. J Immunol (2008) 1.75
Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors. Immunity (2015) 1.74
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. J Exp Med (2007) 1.71
Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes. Cell (2012) 1.70
The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol Rev (2009) 1.70
Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells. Nat Immunol (2005) 1.65
CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion. PLoS Pathog (2013) 1.65
Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node. Immunity (2013) 1.65
A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity. Infect Immun (2006) 1.63
Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proc Natl Acad Sci U S A (2005) 1.62
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Cell (2014) 1.62
Regulation of lymph node vascular growth by dendritic cells. J Exp Med (2006) 1.62
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion. Proc Natl Acad Sci U S A (2007) 1.60
Plasticity in programming of effector and memory CD8 T-cell formation. Immunol Rev (2010) 1.59
In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity. Immunity (2016) 1.59
Keratinocytes function as accessory cells for presentation of endogenous antigen expressed in the epidermis. J Invest Dermatol (2009) 1.59
Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. EMBO J (2009) 1.58
Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis. J Clin Invest (2012) 1.57
Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity. PLoS Biol (2008) 1.57
The impact of negative selection on thymocyte migration in the medulla. Nat Immunol (2009) 1.56
Immunological synapse arrays: patterned protein surfaces that modulate immunological synapse structure formation in T cells. Proc Natl Acad Sci U S A (2006) 1.56
Elimination of self-reactive T cells in the thymus: a timeline for negative selection. PLoS Biol (2013) 1.55
Understanding the structure and function of the immunological synapse. Cold Spring Harb Perspect Biol (2010) 1.54
A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction. Immunity (2008) 1.52
Analysing immune cell migration. Nat Rev Immunol (2009) 1.52
Novel multiwavelength microscopic scanner for mouse imaging. Neoplasia (2005) 1.52
Intravital microscopy: a novel tool to study cell biology in living animals. Histochem Cell Biol (2010) 1.51
Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science (2014) 1.51
Generation and maintenance of memory CD4(+) T Cells. Curr Opin Immunol (2009) 1.50
Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen. Proc Natl Acad Sci U S A (2012) 1.50
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature (2003) 7.56
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature (2007) 4.88
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature (2010) 3.71
CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function. J Exp Med (2002) 3.28
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity (2007) 3.07
The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity (2004) 2.54
Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. J Virol (2004) 2.35
Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes. Cell (2012) 1.70
Travellers in many guises: the origins and destinations of dendritic cells. Immunol Cell Biol (2002) 1.38
Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas. Hum Pathol (2005) 1.26
How antigen quantity and quality determine T-cell decisions in lymphoid tissue. Mol Cell Biol (2008) 1.20
Defining the quantitative limits of intravital two-photon lymphocyte tracking. Proc Natl Acad Sci U S A (2011) 1.17
CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes. J Exp Med (2004) 1.15
Towards estimating the true duration of dendritic cell interactions with T cells. J Immunol Methods (2009) 0.98
Trafficking of murine hematopoietic stem and progenitor cells in health and vascular disease. Microcirculation (2009) 0.78
Gene expression profiling in malignant lymphomas. Adv Exp Med Biol (2007) 0.77
Detecting and characterizing individual molecules with single nanopores. Methods Mol Biol (2012) 0.76
Integrating clinical perspectives into graduate education. Clin Immunol (2011) 0.75
Approaching process improvement from a human factors perspective: seeking leverage from a systems approach. Surgery (2008) 0.75
SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19. medRxiv (2020) 0.75