Published in J Neurosci on January 14, 2004
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci (2009) 2.21
Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci Biobehav Rev (2008) 1.65
Pharmacological targeting of the serotonergic system for the treatment of obesity. J Physiol (2008) 1.48
Role of the corticotropin-releasing factor receptor type 2 in the control of food intake in mice: a meal pattern analysis. Eur J Neurosci (2007) 1.15
The role of serotonin receptor subtypes in treating depression: a review of animal studies. Psychopharmacology (Berl) (2010) 1.08
Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philos Trans R Soc Lond B Biol Sci (2012) 1.07
Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc Natl Acad Sci U S A (2007) 1.06
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology (2013) 0.99
Annual Research Review: New frontiers in developmental neuropharmacology: can long-term therapeutic effects of drugs be optimized through carefully timed early intervention? J Child Psychol Psychiatry (2011) 0.95
Neonatal serotonin depletion alters behavioral responses to spatial change and novelty. Brain Res (2007) 0.94
Structure and function of serotonin G protein-coupled receptors. Pharmacol Ther (2015) 0.94
Behavioral destabilization induced by the selective serotonin reuptake inhibitor fluoxetine. Mol Brain (2011) 0.90
The nucleus accumbens 5-HTR₄-CART pathway ties anorexia to hyperactivity. Transl Psychiatry (2012) 0.85
Alteration by p11 of mGluR5 localization regulates depression-like behaviors. Mol Psychiatry (2015) 0.84
Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin. PLoS One (2015) 0.84
Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy'). Psychopharmacology (Berl) (2010) 0.84
Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model. PLoS One (2015) 0.83
Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants. Neuroscientist (2014) 0.82
Treatment-resistant depression: are animal models of depression fit for purpose? Psychopharmacology (Berl) (2015) 0.81
Four exons of the serotonin receptor 4 gene are associated with multiple distant branch points. RNA (2010) 0.80
Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass. Obesity (Silver Spring) (2012) 0.79
The role of different serotonin receptor subtypes in seizure susceptibility. Exp Brain Res (2013) 0.79
Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice. PLoS One (2010) 0.78
Serotonin receptors in depression: from A to B. F1000Res (2017) 0.77
Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4 receptor and its consequences in early BALB/c mouse embryonic development. BMC Dev Biol (2007) 0.77
The use of animal models to decipher physiological and neurobiological alterations of anorexia nervosa patients. Front Endocrinol (Lausanne) (2015) 0.77
Functional associations among G protein-coupled neurotransmitter receptors in the human brain. BMC Neurosci (2014) 0.77
Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs. Front Neurosci (2016) 0.77
Familial risk for major depression is associated with lower striatal 5-HT₄ receptor binding. Int J Neuropsychopharmacol (2014) 0.76
Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link? Front Pharmacol (2015) 0.76
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor. Angiogenesis (2012) 0.75
Brain serotonin 4 receptor binding is inversely associated with verbal memory recall. Brain Behav (2017) 0.75
How Does the Brain Implement Adaptive Decision Making to Eat? J Neurosci (2015) 0.75
The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors. Front Cell Neurosci (2017) 0.75
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet (2002) 7.40
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci U S A (2006) 5.83
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron (2009) 5.20
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature (2011) 5.17
Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (2004) 4.31
Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature (2008) 4.09
Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature (2002) 3.92
Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron (2004) 3.26
Repeated cortico-striatal stimulation generates persistent OCD-like behavior. Science (2013) 3.26
Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci (2008) 3.13
Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci (2006) 3.00
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron (2007) 2.98
Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci (2005) 2.96
Hippocampal neurogenesis: regulation by stress and antidepressants. Biol Psychiatry (2006) 2.94
Targeted gene expression in dopamine and serotonin neurons of the mouse brain. J Neurosci Methods (2004) 2.80
5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron (2010) 2.75
Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus. Neuron (2013) 2.74
Different data from different labs: lessons from studies of gene-environment interaction. J Neurobiol (2003) 2.68
Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology (2009) 2.63
Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron (2011) 2.54
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (2006) 2.49
Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J Neurosci (2004) 2.45
Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol Psychiatry (2008) 2.35
Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders. Proc Natl Acad Sci U S A (2007) 2.29
Engineering GPCR signaling pathways with RASSLs. Nat Methods (2008) 2.29
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiol Dis (2009) 2.29
Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science (2011) 2.25
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci (2009) 2.21
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nat Neurosci (2012) 2.15
Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology (2007) 2.11
Paradoxical influence of hippocampal neurogenesis on working memory. Proc Natl Acad Sci U S A (2007) 1.96
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol Psychiatry (2003) 1.94
Dendritic inhibition in the hippocampus supports fear learning. Science (2014) 1.92
Functional connectome of the striatal medium spiny neuron. J Neurosci (2011) 1.89
Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain (2007) 1.83
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus (2010) 1.67
Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods. J Comb Chem (2007) 1.66
Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. J Neurosci (2003) 1.64
Neurogenesis and affective disorders. Eur J Neurosci (2011) 1.64
GPCR interacting proteins (GIP). Pharmacol Ther (2004) 1.61
Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward. Neuropsychopharmacology (2005) 1.60
Plant insecticide L-canavanine repels Drosophila via the insect orphan GPCR DmX. PLoS Biol (2009) 1.60
Role of adult hippocampal neurogenesis in persistent pain. Pain (2016) 1.56
Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. J Neurosci (2006) 1.55
Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis. Brain Res (2002) 1.53
Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. Curr Med Res Opin (2006) 1.53
Adult-born hippocampal neurons promote cognitive flexibility in mice. Hippocampus (2012) 1.50
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. J Neurosci (2009) 1.50
4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning. Hippocampus (2011) 1.47
Neurodevelopmental origins of depressive disorders. Curr Opin Pharmacol (2006) 1.44
A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL). J Biol Chem (2002) 1.42
Molecular characterization of a purified 5-HT4 receptor: a structural basis for drug efficacy. J Biol Chem (2005) 1.41
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. J Cell Sci (2004) 1.40
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.40
Genetics of affective and anxiety disorders. Annu Rev Psychol (2006) 1.40
Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path. J Neurosci (2012) 1.38
Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Cell Tissue Res (2006) 1.38
GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem (2009) 1.36
Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach. EMBO J (2002) 1.35
GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation. Trends Pharmacol Sci (2007) 1.33
Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy. Exp Neurol (2008) 1.33
Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J Neurosci (2004) 1.32
The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks. FEBS Lett (2003) 1.32
5-HT7 receptor is coupled to G alpha subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology. J Neurosci (2005) 1.31
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors. Mol Pharmacol (2009) 1.29
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. J Neurosci (2011) 1.27
Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biol Psychiatry (2012) 1.25
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem (2004) 1.25
Increased fear response to contextual cues in mice lacking the 5-HT1A receptor. Neuropsychopharmacology (2006) 1.24
NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination. J Neurosci (2012) 1.22
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient. J Biol Chem (2011) 1.21
The albumin in acute stroke trial (ALIAS); design and methodology. Int J Stroke (2007) 1.21
Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology (2009) 1.20
Epileptiform activity induces vascular remodeling and zonula occludens 1 downregulation in organotypic hippocampal cultures: role of VEGF signaling pathways. J Neurosci (2011) 1.19
Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome. J Biol Chem (2003) 1.18
Epac mediates PACAP-dependent long-term depression in the hippocampus. J Physiol (2008) 1.17
Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression. Neuropsychopharmacology (2013) 1.16
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol Cell Neurosci (2002) 1.15
Altered circulating leukocytes and their chemokines in a clinical trial of therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy*. Pediatr Crit Care Med (2013) 1.13
Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis (2005) 1.12
Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors. J Biol Chem (2008) 1.11
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol (2007) 1.10
Sequencing and genetic variation of multidrug resistance plasmids in Klebsiella pneumoniae. PLoS One (2010) 1.10
5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice. Am J Physiol Gastrointest Liver Physiol (2002) 1.09
The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology (2010) 1.09
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling. Mol Biol Cell (2008) 1.08
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proc Natl Acad Sci U S A (2005) 1.08
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep (2012) 1.08