Published in J Neurosci Methods on November 24, 2004
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. J Neurosci (2010) 3.47
A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell (2009) 3.28
Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. Proc Natl Acad Sci U S A (2009) 2.97
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron (2010) 2.75
Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron (2008) 2.41
A genetic approach to access serotonin neurons for in vivo and in vitro studies. Proc Natl Acad Sci U S A (2005) 2.02
NMDA receptors in dopaminergic neurons are crucial for habit learning. Neuron (2011) 2.02
Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction. Neuron (2011) 1.83
Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission. Neuron (2013) 1.74
Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol (2007) 1.72
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. Proc Natl Acad Sci U S A (2006) 1.69
Regulation of presynaptic neurotransmission by macroautophagy. Neuron (2012) 1.52
Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons. Neuron (2015) 1.47
Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits (2014) 1.32
Serotonergic neurons signal reward and punishment on multiple timescales. Elife (2015) 1.30
α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. J Neurosci (2011) 1.25
Dopamine neuron glutamate cotransmission: frequency-dependent modulation in the mesoventromedial projection. Neuroscience (2009) 1.24
Forging links between human mental retardation-associated CNVs and mouse gene knockout models. PLoS Genet (2009) 1.23
Serotonergic versus nonserotonergic dorsal raphe projection neurons: differential participation in reward circuitry. Cell Rep (2014) 1.18
The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA. Neuron (2010) 1.16
RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc Natl Acad Sci U S A (2007) 1.11
Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala. Mol Psychiatry (2011) 1.11
Transient activation of specific neurons in mice by selective expression of the capsaicin receptor. Nat Commun (2012) 1.10
Organization of monosynaptic inputs to the serotonin and dopamine neuromodulatory systems. Cell Rep (2014) 1.10
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol Neurodegener (2012) 1.10
Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol (2010) 1.07
Sidekick 2 directs formation of a retinal circuit that detects differential motion. Nature (2015) 1.06
An Interglomerular Circuit Gates Glomerular Output and Implements Gain Control in the Mouse Olfactory Bulb. Neuron (2015) 1.05
Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences. Neuropsychopharmacology (2011) 1.03
Transgene expression in target-defined neuron populations mediated by retrograde infection with adeno-associated viral vectors. J Neurosci (2013) 1.02
The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning. J Neurosci (2011) 0.99
Inducible gene manipulations in serotonergic neurons. Front Mol Neurosci (2009) 0.99
Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5-B9) to the forebrain and brainstem. Brain Struct Funct (2014) 0.98
Considerations when using cre-driver rodent lines for studying ventral tegmental area circuitry. Neuron (2015) 0.98
Development and characterization of a new Parkinson's disease model resulting from impaired autophagy. J Neurosci (2012) 0.97
Attenuating GABA(A) receptor signaling in dopamine neurons selectively enhances reward learning and alters risk preference in mice. J Neurosci (2011) 0.95
Disruption of dopamine neuron activity pattern regulation through selective expression of a human KCNN3 mutation. Neuron (2013) 0.95
Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex. J Neurosci (2012) 0.95
VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function. Cell Rep (2015) 0.95
Postnatal growth defects in mice with constitutive depletion of central serotonin. ACS Chem Neurosci (2012) 0.95
The Use of Lentiviral Vectors and Cre/loxP to Investigate the Function of Genes in Complex Behaviors. Front Mol Neurosci (2009) 0.93
The multilingual nature of dopamine neurons. Prog Brain Res (2014) 0.93
Modality-specific thalamocortical inputs instruct the identity of postsynaptic L4 neurons. Nature (2014) 0.93
Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum. J Neurosci (2014) 0.92
Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. J Neurosci (2013) 0.92
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. PLoS One (2010) 0.92
Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain. Neuropsychopharmacology (2012) 0.91
Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors. AAPS J (2006) 0.91
Sorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response. Neuron (2014) 0.89
A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling. Mol Cell Neurosci (2010) 0.88
Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study. Genes Brain Behav (2012) 0.86
Principles of designing interpretable optogenetic behavior experiments. Learn Mem (2015) 0.86
Restoration of dopamine signaling to the dorsal striatum is sufficient for aspects of active maternal behavior in female mice. Endocrinology (2013) 0.85
Addictive drugs and plasticity of glutamatergic synapses on dopaminergic neurons: what have we learned from genetic mouse models? Front Mol Neurosci (2012) 0.84
Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality. PLoS One (2011) 0.84
Defining functional gene-circuit interfaces in the mouse nervous system. Genes Brain Behav (2013) 0.84
Generation of Pet1210-Cre transgenic mouse line reveals non-serotonergic expression domains of Pet1 both in CNS and periphery. PLoS One (2014) 0.83
Reward processing by the dorsal raphe nucleus: 5-HT and beyond. Learn Mem (2015) 0.82
Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons. J Neurosci (2015) 0.82
The Interglomerular Circuit Potently Inhibits Olfactory Bulb Output Neurons by Both Direct and Indirect Pathways. J Neurosci (2016) 0.81
Marked decrease of LSD-induced stimulus control in serotonin transporter knockout mice. Pharmacol Biochem Behav (2007) 0.81
Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proc Natl Acad Sci U S A (2014) 0.81
Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A (2016) 0.80
Visualization of plasticity in fear-evoked calcium signals in midbrain dopamine neurons. Learn Mem (2014) 0.80
Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory. Biol Psychiatry (2015) 0.80
Differential Excitation of Distally versus Proximally Targeting Cortical Interneurons by Unitary Thalamocortical Bursts. J Neurosci (2016) 0.80
Stimulus control by 5-methoxy-N,N-dimethyltryptamine in wild-type and CYP2D6-humanized mice. Pharmacol Biochem Behav (2011) 0.80
Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway. PLoS Genet (2013) 0.80
Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII. J Neurosci (2015) 0.79
Thalamic NMDA receptor function is necessary for patterning of the thalamocortical somatosensory map and for sensorimotor behaviors. J Neurosci (2014) 0.79
Spatial and temporal lineage analysis of a Pitx3-driven Cre-recombinase knock-in mouse model. PLoS One (2012) 0.78
Brain patterning perturbations following PTEN loss. Front Mol Neurosci (2014) 0.77
Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology (2014) 0.77
Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1. Nature (2017) 0.76
rAAV-compatible MiniPromoters for restricted expression in the brain and eye. Mol Brain (2016) 0.76
Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience (2015) 0.76
Divergent in vivo activity of non-serotonergic and serotonergic VGluT3-neurones in the median raphe region. J Physiol (2016) 0.75
An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice. PLoS One (2015) 0.75
Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency. J Neurosci (2016) 0.75
Cell type-specific pharmacology of NMDA receptors using masked MK801. Elife (2015) 0.75
Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model. Cell Death Dis (2016) 0.75
Control of amygdala circuits by 5-HT neurons via 5-HT and glutamate co-transmission. J Neurosci (2017) 0.75
Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity. Proc Natl Acad Sci U S A (2017) 0.75
Genetic Isolation of Hypothalamic Neurons that Regulate Context-Specific Male Social Behavior. Cell Rep (2016) 0.75
Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation. Nat Commun (2017) 0.75
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell (2008) 5.93
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci U S A (2006) 5.83
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron (2009) 5.20
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature (2011) 5.17
Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (2004) 4.31
Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature (2008) 4.09
Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature (2002) 3.92
A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell (2009) 3.28
Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron (2004) 3.26
Repeated cortico-striatal stimulation generates persistent OCD-like behavior. Science (2013) 3.26
Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci (2008) 3.13
Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci (2006) 3.00
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron (2007) 2.98
Hippocampal neurogenesis: regulation by stress and antidepressants. Biol Psychiatry (2006) 2.94
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron (2010) 2.75
5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron (2010) 2.75
Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus. Neuron (2013) 2.74
Different data from different labs: lessons from studies of gene-environment interaction. J Neurobiol (2003) 2.68
Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology (2009) 2.63
Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron (2011) 2.54
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (2006) 2.49
Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J Neurosci (2004) 2.45
Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol Psychiatry (2008) 2.35
Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res (2010) 2.25
Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science (2011) 2.25
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci (2009) 2.21
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nat Neurosci (2012) 2.15
Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology (2007) 2.11
Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice. J Neurosci (2008) 2.11
Paradoxical influence of hippocampal neurogenesis on working memory. Proc Natl Acad Sci U S A (2007) 1.96
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol Psychiatry (2003) 1.94
Dendritic inhibition in the hippocampus supports fear learning. Science (2014) 1.92
Functional connectome of the striatal medium spiny neuron. J Neurosci (2011) 1.89
Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J Neurosci (2008) 1.80
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest (2015) 1.67
Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus (2010) 1.67
Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. J Neurosci (2003) 1.64
Neurogenesis and affective disorders. Eur J Neurosci (2011) 1.64
Role of adult hippocampal neurogenesis in persistent pain. Pain (2016) 1.56
Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. J Neurosci (2006) 1.55
Adult-born hippocampal neurons promote cognitive flexibility in mice. Hippocampus (2012) 1.50
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. J Neurosci (2009) 1.50
4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning. Hippocampus (2011) 1.47
Neurodevelopmental origins of depressive disorders. Curr Opin Pharmacol (2006) 1.44
Mechanism of the 5-hydroxytryptamine 2A receptor-mediated facilitation of synaptic activity in prefrontal cortex. Proc Natl Acad Sci U S A (2007) 1.42
Genetics of affective and anxiety disorders. Annu Rev Psychol (2006) 1.40
Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path. J Neurosci (2012) 1.38
Brain injury and neurofunctional deficit in neonatal mice with hypoxic-ischemic encephalopathy. Behav Brain Res (2003) 1.31
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. J Neurosci (2011) 1.27
Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biol Psychiatry (2012) 1.25
5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology (2009) 1.24
Increased fear response to contextual cues in mice lacking the 5-HT1A receptor. Neuropsychopharmacology (2006) 1.24
NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination. J Neurosci (2012) 1.22
Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology (2009) 1.20
Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression. Neuropsychopharmacology (2013) 1.16
Impact of D2 receptor internalization on binding affinity of neuroimaging radiotracers. Neuropsychopharmacology (2009) 1.15
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. J Neurosci (2004) 1.10
Late measures of brain injury after neonatal hypoxia-ischemia in mice. Stroke (2004) 1.10
Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter. Am J Physiol Gastrointest Liver Physiol (2002) 1.08
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep (2012) 1.08
Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philos Trans R Soc Lond B Biol Sci (2012) 1.07
Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry (2008) 1.07
Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc Natl Acad Sci U S A (2007) 1.06
Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus? Learn Mem (2013) 1.04
Neuronal plasticity and antidepressant actions. Trends Neurosci (2013) 1.03
c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta. J Physiol (2008) 1.02
Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. Int J Neuropsychopharmacol (2007) 1.01
Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. Neuroscientist (2010) 1.00
Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats. J Neurosci (2008) 1.00
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B. J Neurosci (2008) 1.00
Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology (2007) 1.00
Serotonergic regulation of calcium-activated potassium currents in rodent prefrontal cortex. Eur J Neurosci (2005) 0.99
Oxidative stress is the new stress. Nat Med (2005) 0.99
Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus. Hippocampus (2014) 0.99
Flexible Accelerated STOP Tetracycline Operator-knockin (FAST): a versatile and efficient new gene modulating system. Biol Psychiatry (2010) 0.99
The when and where of BDNF and the antidepressant response. Biol Psychiatry (2008) 0.96
Hippocampal neurogenesis and depression. Novartis Found Symp (2008) 0.94
Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. Eur J Neurosci (2006) 0.94
Modeling treatment-resistant depression. Neuropharmacology (2011) 0.93
Dorsal vs ventral hippocampal neurogenesis: implications for cognition and mood. Neuropsychopharmacology (2011) 0.93
Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens. BMC Neurosci (2007) 0.93
Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice. Int J Neuropsychopharmacol (2009) 0.92
Modification of serotonin neuron properties in mice lacking 5-HT1A receptors. Eur J Pharmacol (2002) 0.92
Lentiviral-mediated targeted transgene expression in dorsal spinal cord glia: tool for the study of glial cell implication in mechanisms underlying chronic pain development. J Neurosci Methods (2007) 0.92
Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain. Neuropsychopharmacology (2012) 0.91
Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function. Eur Neuropsychopharmacol (2006) 0.91
Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. J Psychiatry Neurosci (2004) 0.90
Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology (2013) 0.90