Published in Immunity on January 01, 2004
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92
Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A (2005) 6.32
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci U S A (2007) 4.81
Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest (2005) 4.25
Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. J Exp Med (2009) 4.03
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med (2012) 3.33
SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood (2005) 3.22
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J Clin Invest (2006) 2.79
The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood (2005) 2.79
Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood (2006) 2.67
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood (2005) 2.64
Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood (2005) 2.48
Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. Blood (2005) 2.32
Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo. PLoS One (2007) 2.06
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol (2005) 1.93
Cardiac muscle regeneration: lessons from development. Genes Dev (2011) 1.86
Niche recycling through division-independent egress of hematopoietic stem cells. J Exp Med (2009) 1.62
High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc Natl Acad Sci U S A (2006) 1.56
Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells. Proc Natl Acad Sci U S A (2007) 1.50
An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells. PLoS One (2011) 1.47
Stem cell heterogeneity: implications for aging and regenerative medicine. Blood (2012) 1.38
Musculin/MyoR is expressed in kidney side population cells and can regulate their function. J Cell Biol (2005) 1.31
LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells. Stem Cell Reports (2013) 1.28
Hematopoietic stem cell origin of adipocytes. Exp Hematol (2009) 1.28
Stem cell-like properties of the endometrial side population: implication in endometrial regeneration. PLoS One (2010) 1.27
The chemokine GRObeta mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment. Blood (2007) 1.25
Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: mesenchymal cells and fibrocytes. J Comp Neurol (2006) 1.19
IL-6 blocks a discrete early step in lymphopoiesis. Blood (2005) 1.14
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology (2007) 1.13
A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity. Blood (2005) 1.10
Advances in complex multiparameter flow cytometry technology: Applications in stem cell research. Cytometry B Clin Cytom (2009) 1.10
Eicosanoid regulation of hematopoiesis and hematopoietic stem and progenitor trafficking. Leukemia (2010) 1.09
The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs. Blood (2011) 1.02
Integrating new discoveries into the "vicious cycle" paradigm of prostate to bone metastases. Cancer Metastasis Rev (2014) 1.00
Amelioration of a mouse model of osteogenesis imperfecta with hematopoietic stem cell transplantation: microcomputed tomography studies. Exp Hematol (2010) 0.99
Suppression of myeloid cell leukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cells. Gastric Cancer (2012) 0.99
Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. Immunol Rev (2010) 0.97
Reconstitution of the central and peripheral nervous system during salamander tail regeneration. Proc Natl Acad Sci U S A (2012) 0.96
Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche? Blood Cancer J (2012) 0.96
Aging stem cells, latexin, and longevity. Exp Cell Res (2008) 0.94
DeltaNp63α protein triggers epithelial-mesenchymal transition and confers stem cell properties in normal human keratinocytes. J Biol Chem (2011) 0.94
Predicting clonal self-renewal and extinction of hematopoietic stem cells. Proc Natl Acad Sci U S A (2011) 0.94
CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. Leukemia (2013) 0.94
MCP1 directs trafficking of hematopoietic stem cell-derived fibroblast precursors in solid tumor. Am J Pathol (2010) 0.89
Prenatal transplantation of cytokine-stimulated marrow improves early chimerism in a resistant strain combination but results in poor long-term engraftment. Exp Hematol (2006) 0.87
Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver. Development (2016) 0.87
Signal transduction pathways, intrinsic regulators, and the control of cell fate choice. Biochim Biophys Acta (2012) 0.86
"Homing to Niche," a new criterion for hematopoietic stem cells? Immunity (2004) 0.86
Stem cell-like differentiation potentials of endometrial side population cells as revealed by a newly developed in vivo endometrial stem cell assay. PLoS One (2012) 0.84
Hematopoietic stem cells are pluripotent and not just "hematopoietic". Blood Cells Mol Dis (2013) 0.83
Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement. Immunol Allergy Clin North Am (2010) 0.82
Migration and differentiation of transplanted enteric neural crest-derived cells in murine model of Hirschsprung's disease. Cytotechnology (2014) 0.82
Mapping of BrdU label-retaining dental pulp cells in growing teeth and their regenerative capacity after injuries. Histochem Cell Biol (2010) 0.82
A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repair. BMC Biotechnol (2009) 0.81
Hematopoietic stem cells give rise to osteo-chondrogenic cells. Blood Cells Mol Dis (2012) 0.81
Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy. Stem Cells Int (2009) 0.81
Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement. Hematol Oncol Clin North Am (2011) 0.80
An efficient method for single hematopoietic stem cell engraftment in mice based on cell-cycle dormancy of hematopoietic stem cells. Exp Hematol (2010) 0.79
Protective Effect of Ginsenoside Rg1 on Hematopoietic Stem/Progenitor Cells through Attenuating Oxidative Stress and the Wnt/β-Catenin Signaling Pathway in a Mouse Model of d-Galactose-induced Aging. Int J Mol Sci (2016) 0.79
Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity. FASEB J (2014) 0.79
The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis. PLoS Comput Biol (2015) 0.78
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model. Elife (2016) 0.78
Hematopoietic stem cells. Methods Enzymol (2006) 0.78
Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5. PLoS One (2015) 0.77
Responses of BrdU label-retaining dental pulp cells to allogenic tooth transplantation into mouse maxilla. Histochem Cell Biol (2011) 0.77
Decitabine enhances stem cell antigen-1 expression in cigarette smoke extract-induced emphysema in animal model. Exp Biol Med (Maywood) (2015) 0.75
Image-guided transplantation of single cells in the bone marrow of live animals. Sci Rep (2017) 0.75
The hematopoietic stem-cell niche in health and leukemia. Cell Mol Life Sci (2016) 0.75
Hematopoietic stem cell cultures and assays. Methods Mol Biol (2014) 0.75
Regeneration and adult stem cells in the human female reproductive tract. Stem Cells Cloning (2008) 0.75
Unperturbed vs. post-transplantation hematopoiesis: both in vivo but different. Curr Opin Hematol (2016) 0.75
Therapeutic potential of dental stem cells. J Tissue Eng (2017) 0.75
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
"Stemness": transcriptional profiling of embryonic and adult stem cells. Science (2002) 15.55
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol (2009) 6.39
TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proc Natl Acad Sci U S A (2004) 4.60
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nat Med (2006) 4.18
Generation of transgenic non-human primates with germline transmission. Nature (2009) 4.06
Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. J Exp Med (2009) 4.03
New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (2006) 3.98
Identification of a putative intestinal stem cell and early lineage marker; musashi-1. Differentiation (2003) 3.41
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord. Nat Med (2006) 3.28
A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol (2005) 3.19
Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron (2013) 2.90
RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. Proc Natl Acad Sci U S A (2002) 2.79
Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. J Neurosci (2006) 2.79
Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood (2004) 2.72
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science (2005) 2.72
Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell (2008) 2.69
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med (2006) 2.67
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci U S A (2010) 2.52
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature (2004) 2.48
Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood (2005) 2.48
Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice. Hepatology (2007) 2.34
Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol (2005) 2.34
Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation (2003) 2.27
Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet (2011) 2.26
Failure of bone marrow to reconstitute lung epithelium. Am J Respir Cell Mol Biol (2005) 2.26
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain (2012) 2.18
Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proc Natl Acad Sci U S A (2006) 2.17
Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells. Dev Biol (2004) 2.17
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest (2011) 2.13
New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron (2010) 2.12
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett (2003) 2.10
Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci U S A (2011) 2.09
Development of mesenchymal stem cells partially originate from the neural crest. Biochem Biophys Res Commun (2009) 2.08
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell (2003) 2.05
Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation. Mol Ther (2005) 1.99
Dose-dependent response of FGF-2 for lymphangiogenesis. Proc Natl Acad Sci U S A (2004) 1.98
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol (2005) 1.93
The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Cancer Cell (2005) 1.90
Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science (2014) 1.85
In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. FASEB J (2005) 1.80
Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor. J Natl Cancer Inst (2012) 1.76
Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression. Dev Biol (2005) 1.72
Visualization of peripheral nerve degeneration and regeneration: monitoring with diffusion tensor tractography. Neuroimage (2008) 1.70
Gene therapy of prostate cancer with the soluble vascular endothelial growth factor receptor Flk1. Cancer Biol Ther (2002) 1.67
Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells. Stem Cells (2008) 1.67
The RNA-binding protein HuD regulates neuronal cell identity and maturation. Proc Natl Acad Sci U S A (2005) 1.66
Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat Neurosci (2008) 1.65
An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Res (2005) 1.63
Diffusion-tensor neuronal fiber tractography and manganese-enhanced MR imaging of primate visual pathway in the common marmoset: preliminary results. Radiology (2008) 1.57
Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. J Cell Biol (2008) 1.56
Molecular identity of periglomerular and short axon cells. J Neurosci (2010) 1.55
Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo. Haematologica (2005) 1.55
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature (2011) 1.53
Sema3A regulates bone-mass accrual through sensory innervations. Nature (2013) 1.53
Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (2007) 1.53
Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells. Proc Natl Acad Sci U S A (2007) 1.50
Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation. J Neurosurg (2010) 1.50
Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea. Stem Cells (2006) 1.49
Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways. Mol Cell Biol (2008) 1.47
Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. Development (2004) 1.47
Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cereb Cortex (2011) 1.45
Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell. Clin Cancer Res (2007) 1.44
Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells (2010) 1.43
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43
Tumor initiating potential of side population cells in human gastric cancer. Int J Oncol (2009) 1.42
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Mol Biol Cell (2006) 1.40
Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neurooncol (2009) 1.40
An epidural cooling catheter protects the spinal cord against ischemic injury in pigs. Ann Thorac Surg (2005) 1.39
CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Blood (2007) 1.39
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nat Commun (2012) 1.36
Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res (2006) 1.36
Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans. Development (2005) 1.35
Establishment of novel embryonic stem cell lines derived from the common marmoset (Callithrix jacchus). Stem Cells (2005) 1.35
Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α. Nat Protoc (2012) 1.34
Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J Neurochem (2005) 1.34
Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents. J Clin Invest (2010) 1.33
Evaluation of in vitro proliferative activity of human fetal neural stem/progenitor cells using indirect measurements of viable cells based on cellular metabolic activity. J Neurosci Res (2002) 1.33
Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus. J Neurosci (2007) 1.32
Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression. J Clin Invest (2004) 1.31
Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila. Nat Cell Biol (2002) 1.31
Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival. Mol Cancer (2010) 1.31
Musculin/MyoR is expressed in kidney side population cells and can regulate their function. J Cell Biol (2005) 1.31
Beta-catenin activation and epithelial-mesenchymal transition in the pathogenesis of pterygium. Invest Ophthalmol Vis Sci (2007) 1.30
Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils. J Neurosci Res (2004) 1.30
Separation of mu-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. J Neurosci (2006) 1.30
Exogenous control of mammalian gene expression via modulation of translational termination. Nat Med (2006) 1.30
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A (2006) 1.30
Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells. J Clin Invest (2013) 1.30
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. J Clin Invest (2008) 1.29
A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis. J Allergy Clin Immunol (2013) 1.29
LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells. Stem Cell Reports (2013) 1.28
Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy. J Neurosci (2011) 1.28
Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development. Mol Cell Biol (2009) 1.28
Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury. PLoS One (2009) 1.28