Published in Development on February 01, 2004
Anaplastic lymphoma kinase: signalling in development and disease. Biochem J (2009) 3.05
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer (2013) 2.17
Asymmetric Mbc, active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila. Development (2011) 1.11
NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases. J Signal Transduct (2012) 1.02
Anterograde Jelly belly ligand to Alk receptor signaling at developing synapses is regulated by Mind the gap. Development (2010) 0.96
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase. Elife (2015) 0.91
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet (2013) 0.83
Receptor tyrosine kinases in Drosophila development. Cold Spring Harb Perspect Biol (2013) 0.83
Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation. BMC Dev Biol (2007) 0.78
Distinct genetic programs guide Drosophila circular and longitudinal visceral myoblast fusion. BMC Cell Biol (2014) 0.77
The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation. PLoS One (2014) 0.77
Characterisation of the role of Vrp1 in cell fusion during the development of visceral muscle of Drosophila melanogaster. BMC Dev Biol (2010) 0.76
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator. EMBO Rep (2005) 2.80
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer (2013) 2.17
The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning. EMBO J (2007) 2.06
Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila. J Cell Sci (2007) 1.67
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion. Nature (2003) 1.59
Replacement by Drosophila melanogaster protamines and Mst77F of histones during chromatin condensation in late spermatids and role of sesame in the removal of these proteins from the male pronucleus. Mol Cell Biol (2005) 1.56
The Wiskott-Aldrich syndrome protein (WASP) is essential for myoblast fusion in Drosophila. Dev Biol (2007) 1.55
Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. Cell (2007) 1.46
kette and blown fuse interact genetically during the second fusion step of myogenesis in Drosophila. Development (2004) 1.44
Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J (2007) 1.38
WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. J Cell Sci (2008) 1.35
Myoblast fusion in Drosophila melanogaster is mediated through a fusion-restricted myogenic-adhesive structure (FuRMAS). Dev Dyn (2007) 1.33
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. EMBO Rep (2003) 1.24
Characterization of the expression of the ALK receptor tyrosine kinase in mice. Gene Expr Patterns (2006) 1.24
Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo. Biochem J (2002) 1.17
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma. Dis Model Mech (2012) 1.14
Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (2004) 1.14
FuRMAS: triggering myoblast fusion in Drosophila. Dev Dyn (2009) 1.13
Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684. Biochem J (2011) 1.11
Distinct functions of Mst77F and protamines in nuclear shaping and chromatin condensation during Drosophila spermiogenesis. Eur J Cell Biol (2010) 1.10
Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy. Cancer Res (2010) 1.07
Stress-induced PARP activation mediates recruitment of Drosophila Mi-2 to promote heat shock gene expression. PLoS Genet (2011) 1.05
Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines. Blood (2004) 1.02
Crizotinib--latest champion in the cancer wars? N Engl J Med (2010) 1.01
Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. Syst Biol Reprod Med (2010) 0.98
Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth. Neural Dev (2008) 0.95
Blown fuse regulates stretching and outgrowth but not myoblast fusion of the circular visceral muscles in Drosophila. Differentiation (2006) 0.94
The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. PLoS Genet (2011) 0.92
The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo. Transl Oncol (2011) 0.91
The ligand Jelly Belly (Jeb) activates the Drosophila Alk RTK to drive PC12 cell differentiation, but is unable to activate the mouse ALK RTK. J Exp Zool B Mol Dev Evol (2007) 0.91
A new translational repression element and unusual transcriptional control regulate expression of don juan during Drosophila spermatogenesis. Mech Dev (2002) 0.90
The formation of syncytia within the visceral musculature of the Drosophila midgut is dependent on duf, sns and mbc. Mech Dev (2002) 0.90
Drosophila rolling pebbles colocalises and putatively interacts with alpha-Actinin and the Sls isoform Zormin in the Z-discs of the sarcomere and with Dumbfounded/Kirre, alpha-Actinin and Zormin in the terminal Z-discs. J Muscle Res Cell Motil (2006) 0.89
Three levels of regulation lead to protamine and Mst77F expression in Drosophila. Dev Biol (2013) 0.88
Miple1 and miple2 encode a family of MK/PTN homologues in Drosophila melanogaster. Dev Genes Evol (2005) 0.88
The role of LamininB2 (LanB2) during mesoderm differentiation in Drosophila. Cell Mol Life Sci (2011) 0.87
Fusion of circular and longitudinal muscles in Drosophila is independent of the endoderm but further visceral muscle differentiation requires a close contact between mesoderm and endoderm. Mech Dev (2009) 0.86
Transcriptional regulation of Profilin during wound closure in Drosophila larvae. J Cell Sci (2012) 0.86
ALK and NSCLC: Targeted therapy with ALK inhibitors. F1000 Med Rep (2011) 0.85
Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation. EMBO J (2013) 0.85
The bromodomain-containing protein tBRD-1 is specifically expressed in spermatocytes and is essential for male fertility. Biol Open (2012) 0.85
Subunits of the histone chaperone CAF1 also mediate assembly of protamine-based chromatin. Cell Rep (2013) 0.83
Mutation of Drosophila focal adhesion kinase induces bang-sensitive behavior and disrupts glial function, axonal conduction and synaptic transmission. Eur J Neurosci (2008) 0.83
Kinesin-2 differentially regulates the anterograde axonal transports of acetylcholinesterase and choline acetyltransferase in Drosophila. J Neurobiol (2006) 0.83
Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. BMC Dev Biol (2008) 0.83
Drosophila Swiprosin-1/EFHD2 accumulates at the prefusion complex stage during Drosophila myoblast fusion. J Cell Sci (2011) 0.83
The bHLH transcription factor Hand is regulated by Alk in the Drosophila embryonic gut. Biochem Biophys Res Commun (2006) 0.83
Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt. Cell Microbiol (2006) 0.83
Multinucleated smooth muscles and mononucleated as well as multinucleated striated muscles develop during establishment of the male reproductive organs of Drosophila melanogaster. Dev Biol (2012) 0.82
Jeb/Alk signalling regulates the Lame duck GLI family transcription factor in the Drosophila visceral mesoderm. Development (2013) 0.82
Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity. FEBS J (2006) 0.82
The ADAM metalloprotease Kuzbanian is crucial for proper heart formation in Drosophila melanogaster. Mech Dev (2006) 0.81
Drosophila Anaplastic Lymphoma Kinase regulates Dpp signalling in the developing embryonic gut. Differentiation (2007) 0.81
Myosin heavy chain-like localizes at cell contact sites during Drosophila myoblast fusion and interacts in vitro with Rolling pebbles 7. Exp Cell Res (2012) 0.81
In Drosophila melanogaster, the rolling pebbles isoform 6 (Rols6) is essential for proper Malpighian tubule morphology. Mech Dev (2005) 0.81
Pattern of tissue invasion by Propionibacterium acnes in acne vulgaris. J Dermatol Sci (2012) 0.81
Intragenic anaplastic lymphoma kinase (ALK) rearrangements: translocations as a novel mechanism of ALK activation in neuroblastoma tumors. Genes Chromosomes Cancer (2014) 0.80
Tethering membrane fusion: common and different players in myoblasts and at the synapse. J Neurogenet (2014) 0.80
Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3 proteins. Biochem J (2010) 0.78
Distinct genetic programs guide Drosophila circular and longitudinal visceral myoblast fusion. BMC Cell Biol (2014) 0.77
The Hydra FGFR, Kringelchen, partially replaces the Drosophila Heartless FGFR. Dev Genes Evol (2012) 0.77
The syncytial visceral and somatic musculature develops independently of β3-Tubulin during Drosophila embryogenesis, while maternally supplied β1-Tubulin is stable until the early steps of myoblast fusion. Eur J Cell Biol (2012) 0.76
Characterisation of the role of Vrp1 in cell fusion during the development of visceral muscle of Drosophila melanogaster. BMC Dev Biol (2010) 0.76
The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. PLoS One (2010) 0.75
Spatial distribution of bacterial-fungal communities in facial skin. J Dermatol Sci (2012) 0.75
Microbiology of folliculitis: a histological study of 39 cases. APMIS (2013) 0.75
Simultaneous visualization of Propionibacterium acnes and Propionibacterium granulosum with immunofluorescence and fluorescence in situ hybridization. Anaerobe (2013) 0.75
Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation. Br J Haematol (2006) 0.75